Search results for "iOS"
showing 10 items of 8115 documents
An Efficient Synthesis of γ-Aminoacids and Attempts to Drive Its Enantioselectivity
2008
Addition of carboxylic acid dianions to bromoacetonitrile lead, in good yields,to the corresponding gamma-cyanoacids, which on hydrogenation yielded gamma-amino acids. This two step methodology improves upon previously described results. Poor e.e's resultedfrom our attempts to drive the enantioselectivity of this transformation by chiral amide induction.
A simple synthesis of γ-aminoacids
2007
The addition of dianions of carboxylic acids to bromoacetonitrile, leads, in good yields, to the corresponding γ-cyanoacids that give γ-aminoacids on hydrogenation. This two-step methodology improves the results previously described.
Closure of oroantral communications with Bichat´s buccal fat pad. Level of patient satisfaction
2015
Purpose: To report the closure of oroantral communications with the pedicled buccal fat pad in a series of patients, and to determine the level of patient satisfaction after the surgery. Study Design: A prospective study of patients diagnosed of unilateral or bilateral oroantral communication (OAC) closed using the buccal fat pad between May 2012 and January 2013 was performed. Data analysis extended to: age, sex, and cause, location and size of oroantral communication. Complications and success related to buccal fat pad surgery were evaluated. Also, patient satisfaction was assessed after six months of surgery. Results: Nine patients (3 men and 6 women) with a mean age of 50.5 years and 11…
Barrier effects on the spatial distribution of Xylella fastidiosa in Alicante, Spain
2021
AbstractSpatial models often assume isotropy and stationarity, implying that spatial dependence is direction invariant and uniform throughout the study area. However, these assumptions are violated when dispersal barriers are present in the form of geographical features or disease control interventions. Despite this, the issue of non-stationarity has been little explored in the context of plant health. The objective of this study was to evaluate the influence of different barriers in the distribution of the quarantine plant pathogenic bacterium Xylella fastidiosa in the demarcated area in Alicante, Spain. Occurrence data from the official surveys in 2018 were analyzed with four spatial Baye…
Biosynthesis of Sinapigladioside, an Antifungal Isothiocyanate from Burkholderia Symbionts
2021
Abstract Sinapigladioside is a rare isothiocyanate‐bearing natural product from beetle‐associated bacteria (Burkholderia gladioli) that might protect beetle offspring against entomopathogenic fungi. The biosynthetic origin of sinapigladioside has been elusive, and little is known about bacterial isothiocyanate biosynthesis in general. On the basis of stable‐isotope labeling, bioinformatics, and mutagenesis, we identified the sinapigladioside biosynthesis gene cluster in the symbiont and found that an isonitrile synthase plays a key role in the biosynthetic pathway. Genome mining and network analyses indicate that related gene clusters are distributed across various bacterial phyla including…
Insect-associated bacteria assemble the antifungal butenolide gladiofungin by non-canonical polyketide chain termination
2020
Abstract Genome mining of one of the protective symbionts (Burkholderia gladioli) of the invasive beetle Lagria villosa revealed a cryptic gene cluster that codes for the biosynthesis of a novel antifungal polyketide with a glutarimide pharmacophore. Targeted gene inactivation, metabolic profiling, and bioassays led to the discovery of the gladiofungins as previously‐overlooked components of the antimicrobial armory of the beetle symbiont, which are highly active against the entomopathogenic fungus Purpureocillium lilacinum. By mutational analyses, isotope labeling, and computational analyses of the modular polyketide synthase, we found that the rare butenolide moiety of gladiofungins deriv…
Fire severity estimation in southern of the Buenos Aires province, Argentina, using Sentinel-2 and its comparison with Landsat-8
2018
[EN] Assessment of rural fire severity is fundamental to evaluate fire damages and to analyze recovery processes in a low-cost and efficient way. Burnt areas covering shrubs and grasslands were estimated in more than 30,000 km2 in Argentina from December 2016 to January 2017. The study area presented in this work is located in the South of the Buenos Aires province, and it covers a semiarid area with the presence of xerophilous shrubs and grasslands. This is one of the most abundant ecosystem in Central and Southern Argentina. Field campaigns were carried out over the area affected by the fire in order to georreference the burnt plots and characterized the fire severity in 5 levels. The obj…
El antiterrorismo como coartada
2001
Contre l'anti-terrorisme comme alibi
2001
Se trata de la versión francesa del artículo "El antiterrorismo como coartada", publicado en "El País" el 10 de noviembre de 2001. El texto en francés supuestamente fue publicado en la revista de "Les amis de 'Le monde diplomatique'", aunque la versión de la que se dispone no es la publicada.