Search results for "imagin."

Visual Contrast Modulates Operant Learning Responses in Larval Zebrafish.

2018

The larval zebrafish is a promising vertebrate model organism to study neural mechanisms underlying learning and memory due to its small brain and rich behavioral repertoire. Here, we report on a high-throughput operant conditioning system for zebrafish larvae, which can simultaneously train 12 fish to associate a visual conditioned pattern with electroshocks. We find that the learning responses can be enhanced by the visual contrast, not the spatial features of the conditioned patterns, highlighted by several behavioral metrics. By further characterizing the learning curves as well as memory extinction, we demonstrate that the percentage of learners and the memory length increase as the co…

AnatomySketch : An Extensible Open-Source Software Platform for Medical Image Analysis Algorithm Development

2021

AbstractThe development of medical image analysis algorithm is a complex process including the multiple sub-steps of model training, data visualization, human–computer interaction and graphical user interface (GUI) construction. To accelerate the development process, algorithm developers need a software tool to assist with all the sub-steps so that they can focus on the core function implementation. Especially, for the development of deep learning (DL) algorithms, a software tool supporting training data annotation and GUI construction is highly desired. In this work, we constructed AnatomySketch, an extensible open-source software platform with a friendly GUI and a flexible plugin interfac…

Highly sensitive olfactory biosensors for the detection of volatile organic compounds by surface plasmon resonance imaging

2018

International audience; Nowadays, monitoring of volatile organic compounds (VOCs) is very important in various domains. In this work, we aimed to develop sensitive olfactory biosensors using odorant binding proteins (OBPs) as sensing materials. Three rat OBP3 derivatives with customized binding properties were designed and immobilized on the same chip for the detection of VOCs in solution by surface plasmon resonance imaging (SPRi). We demonstrated that the proteins kept their binding properties after the immobilization under optimized conditions. The obtained olfactory biosensors exhibited very low limits of detection in both concentration (200pM of beta-ionone) and in molecular weight of …

Ortho -Functionalized Aryltetrazines by Direct Palladium-Catalyzed C−H Halogenation: Application to Fast Electrophilic Fluorination Reactions

2016

International audience; A general catalyzed direct C-H functionalization of s-tetrazines is reported. Under mild reaction conditions, N-directed ortho-C-H activation of tetrazines allows the introduction of various functional groups, thus forming carbon-heteroatom bonds: C-X (X=I, Br, Cl) and C-O. Based on this methodology, we developed electrophilic mono- and poly-ortho-fluorination of tetrazines. Microwave irradiation was optimized to afford fluorinated s-aryltetrazines, with satisfactory selectivity, within only ten minutes. This work provides an efficient and practical entry for further accessing highly substituted tetrazine derivatives (iodo, bromo, chloro, fluoro, and acetate precurso…

Characterization of three-dimensional microstructure of composite materials by X-ray tomography

2016

Analysis methods for X-ray microtomographic images of short fibre composite materials were developed. The methods enable estimation of microstructural properties of the material, e.g., aspect ratio and orientation of fibres. Being based on X-ray microtomography and image analysis, the methods are nondestructive and do not require user intervention. In particular, a method for determination of the aspect ratio of fibres was first developed. The method contains an assumption about similarity of the shape of the fibres. The assumption was relaxed in an improved method that can estimate cross-sectional properties of fibres, too, e.g., cross-sectional area. Additionally, the effect of finite ima…

Język metaforyczny w modelu Wrocławskiej Szkoły Przyszłości

2020

W niniejszym artykule poszukuję odpowiedzi na pytanie: Jakie są sensy i znaczenia metafor we Wrocławskiej Szkole Przyszłości (WSP)? Ukazuję zastosowanie języka metaforycznego w szkole, gdzie metaforę traktuje się jako źródło wiedzy o otaczającym świecie, jako swoiste wspomaganie efektywniejszej komunikacji oraz jako stymulator wyobraźni. We WSP uważa się, że dziecko nie musi być skazane na edukację opartą na stereotypowych zachowaniach. Uważa się tam, że w procesie edukacji potrzebne jest myślenie kreatywne, oparte na rozmaitych skojarzeniach, w których wykorzystywana jest umiejętność tworzenia mapy myśli, wyobraźni, czyli tzw. edukacja z wyobraźnią. Taką edukację we Wrocławskiej Szkole Prz…

Wyobraźnia teoriopolityczna jako dyrektywa poznawcza

2018

The Large Observatory For x-ray Timing

2014

The Large Observatory For x-ray Timing (LOFT) was studied within ESA M3 Cosmic Vision framework and participated in the final down-selection for a launch slot in 2022-2024. Thanks to the unprecedented combination of effective area and spectral resolution of its main instrument, LOFT will study the behaviour of matter under extreme conditions, such as the strong gravitational field in the innermost regions of accretion flows close to black holes and neutron stars, and the supra-nuclear densities in the interior of neutron stars. The science payload is based on a Large Area Detector (LAD, 10 m 2 effective area, 2-30 keV, 240 eV spectral resolution, 1 deg collimated field of view) and a WideFi…

Hydrogels for Three-Dimensional Ionizing-Radiation Dosimetry

2021

Radiation-sensitive gels are among the most recent and promising developments for radiation therapy (RT) dosimetry. RT dosimetry has the twofold goal of ensuring the quality of the treatment and the radiation protection of the patient. Benchmark dosimetry for acceptance testing and commissioning of RT systems is still based on ionization chambers. However, even the smallest chambers cannot resolve the steep dose gradients of up to 30–50% per mm generated with the most advanced techniques. While a multitude of systems based, e.g., on luminescence, silicon diodes and radiochromic materials have been developed, they do not allow the truly continuous 3D dose measurements offered by radiation-se…

"On-the-go" multispectral imaging system embedded on a track laying tractor to characterize the vine foliage

2015

Mutispectral imaging systems are widely used in remote sensing for Precision Viticulture. In this work, this technique was applied in the proximal sensing context to characterize vine foliage. A mobile terrestrial experimental system is presented, composed of a GPS receiver, a multi-spectral camera acquiring visible and near infrared images, and a Greenseeker RT-100 which measures the Normalized Difference Vegetative Index (NDVI). This optical system observes vine foliage in the trellis plan, in natural sunlight. The experimental field is planted with Chardonnay, Pinot Noir and Meunier cultivars in a latin squared pattern. In 2013, six datasets were acquired at various phenological stages.S…