Search results for "intermediate"
showing 10 items of 440 documents
Measurement of high energy resolution inelastic proton scattering at and close to zero degrees
2009
13 pages, 15 figures.-- Printed version published Jul 1, 2009.
Probing the Merits of Different Event Parameters for the Identification of Light Charged Particles in CHIMERA CsI(Tl Detectors With Digital Pulse Sha…
2013
We investigated the merits of different event parameters in the identification of Light Charged Particles (LCPs) with CsI(Tl) scintillators read out by photodiodes at high incident energy (400 MeV/u). This investigation is made possible by digital signal processing the output signals. As in the conventional analogue case, the digitized signals allow the discrimination of light charged particles by computing the fast and slow components. In addition other identification parameters as the rise time of the output pulses of the CsI(Tl) come out nearly for free. Aim of this paper is the investigation of novel identification plots and the probe of their merits, in particular at relativistic energ…
Measurement of the beam-helicity asymmetry in photoproduction of π0η pairs on carbon, aluminum, and lead
2020
The beam-helicity asymmetry was measured, for the first time, in photoproduction of $\pi^{0}\eta$ pairs on carbon, aluminum, and lead, with the A2 experimental setup at MAMI. The results are compared to an earlier measurement on a free proton and to the corresponding theoretical calculations. The Mainz model is used to predict the beam-helicity asymmetry for the nuclear targets. The present results indicate that the photoproduction mechanism for $\pi^{0}\eta$ pairs on nuclei is similar to photoproduction on a free nucleon. This process is dominated by the $D_{33}$ partial wave with the $\eta\Delta(1232)$ intermediate state.
Search for right-handed W bosons in top quark decay
2005
We present a measurement of the fraction f+ of right-handed W bosons produced in top quark decays, based on a candidate sample of $t\bar{t}$ events in the lepton+jets decay mode. These data correspond to an integrated luminosity of 230pb^-1, collected by the DO detector at the Fermilab Tevatron $p\bar{p}$ Collider at sqrt(s)=1.96 TeV. We use a constrained fit to reconstruct the kinematics of the $t\bar{t}$ and decay products, which allows for the measurement of the leptonic decay angle $\theta^*$ for each event. By comparing the $\cos\theta^*$ distribution from the data with those for the expected background and signal for various values of f+, we find f+=0.00+-0.13(stat)+-0.07(syst). This …
0.1-10 MeV Neutron Soft Error Rate in Accelerator and Atmospheric Environments
2021
Neutrons with energies between 0.1-10 MeV can significantly impact the Soft Error Rate (SER) in SRAMs manufactured in scaled technologies, with respect to high-energy neutrons. Their contribution is evaluated in accelerator, ground level and avionic (12 km of altitude) environments. Experimental cross sections were measured with monoenergetic neutrons from 144 keV to 17 MeV, and results benchmarked with Monte Carlo simulations. It was found that even 144 keV neutrons can induce upsets due to elastic scattering. Moreover, neutrons in the 0.1-10 MeV energy range can induce more than 60% of the overall upset rate in accelerator applications, while their contribution can exceed 18% in avionics.…
Critères de substitution: méthodes de validation et état des lieux en cancérologie digestive
2009
In oncology, overall survival is often referred to as the gold standard for the evaluation of a novel therapy in phase III clinical trials. The use of an earlier endpoint (intermediate endpoint) would allow to reduce the duration, the number of patients and/or the cost of the studies. Before being used as primary endpoint, it has to be validated as surrogate for overall survival. Two main statistical methods have been developed. The first evaluates the proportion of treatment effect on overall survival that can be attributable to the effect on the surrogate endpoint. The second, the meta-analytic approach, estimates the correlation between the treatment effect on the surrogate and its effec…
Intermediate and Advanced Hepatocellular Carcinoma Management in four Italian Centers: Patterns of Treatment and Costs.
2015
A RANDOMISED STUDY EVALUATING MAINTENANCE SCHEDULE IN EARLY ADJUVANT CHEMOTHERAPY FOR INTERMEDIATE RISK NON-MUSCLE-INVASIVE BLADDER CANCER
2008
ABSTRACT Introduction and Objective: Adjuvant intravesical chemotherapy or BCG immunotherapy after transurethral resection (TUR) is a standard treatment for non–muscle-invasive transitional cell cancer of the bladder (NMI TCCB) at intermediate risk. Although the clinical value of early intravesical adjuvant chemotherapy is well established, the optimal schedule regimen and the role of maintenance is still debated. Methods: Between May 2002 and August 2003, 577 patients, undergoing TUR for NMI TCCB, were recruited. All patients underwent TUR and early (within 6 hours) intravesical chemotherapy with epirubicin at the dose of 80 mg diluted in 60 ml of saline solution. When histology was availa…
The Recomposition of Bureaucratic Forms in Territorial Development. Territorial Engineering and Intermediation in Project Territories
2013
L’ingénierie territoriale mobilise un répertoire de savoirs et d’objets intermédiaires au cœur du processus de création territoriale. Cet équipement cognitif est nécessaire à la cohésion de l’action publique multiniveaux au sein du territoire de projet. Dans ce contexte, bien que les modalités de gestion des contrats d’action publique ne dénaturent par la fonction médiatrice de ce répertoire, elles sont standardisées par les forces de l’isomorphisme institutionnel. L’ingénierie territoriale se bureaucratisant, elle administre des procédures qui font des territoires des segments d’exécution d’une politique définie indépendamment des enjeux territoriaux. At the heart of territorial processing…
Enhanced susceptibility of cholesteryl sulfate-enriched low density lipoproteins to copper-mediated oxidation
1995
AbstractCholesteryl sulfate (CS) is a minor component of cell membranes, also present in lipoproteins, and its exact function is unknown. Since oxidation of low density lipoproteins (LDL) is thought to be an important determinant of atherogenesis, we investigated the influence of CS enrichment on copper-mediated oxidation of LDL. CS was found to act as a pro-oxidant, as measured by lipid oxidation parameters. The results also suggest that these effects were dependent on the sulfate group since pure cholesterol or cholesteryl acetate did not promote Cu2+-mediated oxidation. Our findings imply that CS may affect the oxidizability and hence the potential atherogenicity of LDL.