Search results for "interval"

showing 10 items of 1703 documents

Association between the 2018 WCRF/AICR and the Low-Risk Lifestyle Scores with Colorectal Cancer Risk in the Predimed Study

2020

Limited longitudinal studies have been conducted to evaluate colorectal cancer (CRC) incidence based on the updated 2018 World Cancer Research Fund/American Institute for Cancer Research (WCRF/AICR) recommendations or other global lifestyle indices, and none in aged populations at high cardiovascular risk. We aimed to assess the association between CRC incidence and adherence to two emerging lifestyles indices (2018 WCRF/AICR score and another low-risk lifestyle (LRL) score comprising smoking status, alcohol consumption, physical activity, diet, and body mass index) in the Spanish PREvencion con DIeta MEDiterranea (PREDIMED) cohort. We studied 7216 elderly men and women at high cardiovascul…

PREDIMEDmedicine.medical_specialtyEstils de vidaColorectal cancerWCRF/AICR scoreLifestyleslcsh:Medicinecolorectal cancerArticle03 medical and health sciences0302 clinical medicineInterquartile rangeCàncer colorectalInternal medicinemedicinelifestyle patterns030212 general & internal medicineAICR scorebusiness.industryIncidence (epidemiology)Hazard ratiolcsh:RGeneral Medicinemedicine.diseasePredimedConfidence intervalWCRFlow-risk lifestyle index030220 oncology & carcinogenesisCohortbusinessBody mass indexJournal of Clinical Medicine
researchProduct

Adverse effects of lingual and buccal orthodontic techniques: A systematic review and meta-analysis

2016

INTRODUCTION: The aim of this systematic review was to assess the prevalence of adverse effects associated with lingual and buccal fixed orthodontic techniques. METHODS: Two authors searched the PubMed, EMBASE, Cochrane Library, and LILACS databases up to October 2014. Agreement between the authors was quantified by the Cohen kappa statistic. The following variables were analyzed: pain, caries, eating and speech difficulties, and oral hygiene. The Newcastle-Ottawa scale was used to assess risk of bias in nonrandomized studies, and the Cochrane Collaboration's tool for assessing risk of bias was used for randomized controlled trials. RESULTS: Eight articles were included in this systematic r…

PainDentistryOdontologíaOrthodonticsCochrane LibraryOral hygienelaw.invention03 medical and health sciences0302 clinical medicineOrthodontic AppliancesTongueRandomized controlled trialTonguelawmedicineHumansOrthodontic Appliance Design030212 general & internal medicineMouthbusiness.industry030206 dentistryOdds ratiomedicine.diseaseConfidence intervalOrtodonciamedicine.anatomical_structureMeta-analysisMalocclusionbusinessMalocclusionAmerican Journal of Orthodontics and Dentofacial Orthopedics
researchProduct

B-mode versus A-mode ultrasonographic measurements of mucosal thickness in vivo

2002

Abstract Objective: The objective of this study was to compare the measurement accuracy of A-mode and B-mode ultrasonographic assessments of palatal masticatory mucosal thickness in vivo. Study Design: Thickness of palatal masticatory mucosa in the molar region of 50 volunteers was measured once with a B-mode ultrasound device (10 MHz) combined with a standoff for intraoral applications. At identical reading points thickness was also assessed with an A-mode device (5 replicates) and by needle probing for determination of true thickness. Results: On average true thickness ranged between 2.9 and 3.3 mm (95% confidence intervals; median, 3.1 mm). B-mode ultrasonography overestimated truth by 0…

Palate HardMolarmedicine.medical_specialtyAccuracy and precisionUltrasound devicebusiness.industryLimits of agreementMouth MucosaReproducibility of ResultsSignal Processing Computer-AssistedConfidence intervalSurgeryMasticatory forceOtorhinolaryngologyReference ValuesIn vivoHumansMedicineSurgeryOral SurgeryUltrasonographybusinessNuclear medicineGeneral DentistryUltrasonographyOral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology
researchProduct

Comparison of minimally invasive parathyroidectomy under local anaesthesia and minimally invasive video-assisted parathyroidectomy for primary hyperp…

2016

Background: Primary hyperparathyroidism (PHPT) origins from a solitary adenoma in 70-95% of cases. Moreover, the advances in methods for localizing an abnormal parathyroid gland made minimally invasive techniques more prominent. This study presents a micro-cost analysis of two parathyroidectomy techniques. Patients and methods: 72 consecutive patients who underwent minimally invasive parathyroidectomy, video-assisted (MIVAP, group A, 52 patients) or "open" under local anaesthesia (OMIP, group B, 20 patients) for PHPT were reviewed. Operating room, consumable, anaesthesia, maintenance costs, equipment depreciation and surgeons/anaesthesiologists fees were evaluated. The patient's satisfactio…

Parathyroidectomymedicine.medical_specialtyCostPrimary hyperparathyroidismmedicine.medical_treatmentVideo-Assisted Surgery03 medical and health sciences0302 clinical medicinePatient satisfactionmedicineHumansMinimally Invasive Surgical ProceduresGeneral anaesthesiaSicilyParathyroidectomyHyperparathyroidismbusiness.industryMinimally invasive parathyroidectomyOdds ratioHyperparathyroidism Primarymedicine.diseaseCosts; Minimally invasive parathyroidectomy; Primary hyperparathyroidism; SurgeryConfidence intervalSurgeryTreatment Outcomemedicine.anatomical_structurePatient Satisfaction030220 oncology & carcinogenesisCosts and Cost AnalysisOriginal ArticleSurgery030211 gastroenterology & hepatologyParathyroid glandbusinessPrimary hyperparathyroidismAnesthesia LocalGiornale di Chirurgia - Journal of Surgery
researchProduct

Cross-sectional study of parental knowledge, behaviour and anxiety in management of paediatric fever among German parents

2021

ObjectivesFever is a common symptom among children. Parental lack of knowledge about fever could cause anxiety and lead to unnecessary measures to subside fever. There is little evidence about German parents’ knowledge and their fever management.DesignA cross-sectional study using a paper-based questionnaire.Setting16 kindergartens in Saarbrücken and Saarlouis regional association accepted to participate in the study. Parents from these kindergartens were requested during the pickup time to answer the questionnaire.Participants481 German parents participated in the study, 394 of them were women. Inclusion criteria were good understanding of German and being a parent of at least one child be…

ParentsHealth Knowledge Attitudes Practicemedicine.medical_specialtyAntipyreticsFeverCross-sectional studyAnxietypaediatric infectious disease & immunisationGermanSurveys and QuestionnairesEpidemiologymedicineHumans1506AntipyreticChildbusiness.industryPublic healthpublic healthRPaediatricsGeneral MedicineConfidence intervallanguage.human_languageCross-Sectional StudiesFamily medicinelanguageAnxietyMedicineFemaleepidemiologymedicine.symptombusinessInclusion (education)1719community child healthmedicine.drugBMJ Open
researchProduct

Caspase 9 and Caspase 3 Immunohistochemical Pattern in Skeletal and Cardiac Muscles at Different Times after Death: An Experimental Study on PMI Esti…

2021

(1) Background: The estimation of the post mortem interval (PMI) is a challenge for forensic pathologists because data emerging from methods commonly applied are not always conclusive, since several conditions exist that may affect the reliability of these parameters. Thus, new approaches have been proposed to overcome such a limit. In recent years, several studies have been performed on proteins analyzing their expression/degradation patterns in relation to the progressing of the post mortem interval. (2) Methods: The immunoreactivity patterns of two apoptosis mediators—Caspase 9 and Caspase 3—have been tested in order to evaluate their potential role as markers of the post mortem interval…

Pathologymedicine.medical_specialtyMedicine (General)cardiac muscleforensic sciencesClinical BiochemistryCaspase 3Article03 medical and health sciences0302 clinical medicineR5-920caspase 3Medicine030216 legal & forensic medicineskeletal musclecaspase 9Caspase030304 developmental biologyPost-mortem intervalCaspase-90303 health sciencespost mortem intervalbiologybusiness.industryCardiac muscleSkeletal musclemedicine.anatomical_structureApoptosisbiology.proteinImmunohistochemistrybusinesstime after deathDiagnostics
researchProduct

Hyperspectral imaging reveals spectral differences and can distinguish malignant melanoma from pigmented basal cell carcinomas : A pilot study

2021

Pigmented basal cell carcinomas can be difficult to distinguish from melanocytic tumours. Hyperspectral imaging is a non-invasive imaging technique that measures the reflectance spectra of skin in vivo. The aim of this prospective pilot study was to use a convolutional neural network classifier in hyperspectral images for differential diagnosis between pigmented basal cell carcinomas and melanoma. A total of 26 pigmented lesions (10 pigmented basal cell carcinomas, 12 melanomas in situ, 4 invasive melanomas) were imaged with hyperspectral imaging and excised for histopathological diagnosis. For 2-class classifier (melanocytic tumours vs pigmented basal cell carcinomas) using the majority of…

Pathologymedicine.medical_specialtySkin Neoplasms010504 meteorology & atmospheric sciencesneural network3122 Cancers0211 other engineering and technologiesmalignant melanomaPilot Projects02 engineering and technologyneuroverkotDermatologytyvisolusyöpä3121 Internal medicine01 natural sciencesSensitivity and SpecificityLesionihosyöpäDiagnosis Differentialbasal cell carcinomamedicineHumansBasal cell carcinomaBasal cellProspective StudiesMelanoma021101 geological & geomatics engineering0105 earth and related environmental sciencesbusiness.industryMelanomaspektrikuvausHyperspectral imagingdeep learningGeneral MedicineHyperspectral Imagingdiagnostiikkamedicine.disease3126 Surgery anesthesiology intensive care radiologyReflectivityConfidence interval3. Good healthkoneoppiminenCarcinoma Basal CellRL1-8033121 General medicine internal medicine and other clinical medicinemedicine.symptomDifferential diagnosisbusiness
researchProduct

Total plasma protein in very preterm babies: prognostic value and comparison with illness severity scores

2013

International audience; OBJECTIVE: We aimed to investigate the predictive value for severe adverse outcome of plasma protein measurements on day one of life in very preterm infants and to compare total plasma protein levels with the validated illness severity scores CRIB, CRIB-II, SNAP-II and SNAPPE-II, regarding their predictive ability for severe adverse outcome. METHODS: We analyzed a cohort of infants born at 24-31 weeks gestation, admitted to the tertiary intensive care unit of a university hospital over 10.5 years. The outcome measure was "severe adverse outcome" defined as death before discharge or severe neurological injury on cranial ultrasound. The adjusted odd ratio (aOR) and 95%…

PediatricsMultivariate analysisCritical Care and Emergency MedicineEpidemiology[ SDV.MHEP.PED ] Life Sciences [q-bio]/Human health and pathology/Pediatricslcsh:MedicinePediatricslaw.inventionCohort Studies0302 clinical medicinelawInfant Very Low Birth Weight030212 general & internal medicineProspective StudiesPediatric Epidemiologylcsh:ScienceMultidisciplinaryArea under the curveBlood ProteinsIntensive care unit3. Good healthCohortMedicineInfant PrematureResearch Articlemedicine.medical_specialtyPediatric Critical CareClinical Research DesignBirth weightFluid Management03 medical and health sciencesHypoproteinemia030225 pediatricsInternal medicinemedicineHumansPrematureRetrospective StudiesNutrition[SDV.MHEP.PED]Life Sciences [q-bio]/Human health and pathology/PediatricsReceiver operating characteristicbusiness.industryVery Low Birth Weightlcsh:RInfant NewbornInfantmedicine.diseaseNewbornConfidence intervallcsh:QNeonatologybusiness
researchProduct

Efficacy of Guanfacine Extended Release in Children and Adolescents with Attention-Deficit/Hyperactivity Disorder and Comorbid Oppositional Defiant D…

2020

OBJECTIVE To assess the efficacy of the non-stimulant guanfacine extended release (GXR) on attention-deficit/hyperactivity disorder (ADHD) symptoms in children and adolescents, with and without comorbid oppositional defiant disorder (ODD). METHODS Data were derived from 4 phase 3, randomized, placebo-controlled trials of dose-optimized GXR monotherapy, in which at least 10% of participants had a diagnosis of comorbid ODD. SPD503-312 and SPD503-316 were 10- to 13-week studies of GXR (1-7 mg/d). SPD503-314 and SPD503-307 were 8-week studies of GXR (1-4 mg/d). Efficacy was assessed using the ADHD Rating Scale IV (ADHD-RS-IV) total scores. RESULTS In total, 1,084 participants were included (SPD…

Pediatricsmedicine.medical_specialtyAdolescentDouble-Blind MethodRating scalemental disordersAdrenergic alpha-2 Receptor AgonistsDevelopmental and Educational PsychologymedicineHumansAttention deficit hyperactivity disorderPooled dataChildPsychiatric Status Rating ScalesDose-Response Relationship Drugbusiness.industrymedicine.diseaseConfidence intervalGuanfacineGuanfacinePsychiatry and Mental healthTreatment OutcomeAttention Deficit Disorder with HyperactivityAttention Deficit and Disruptive Behavior DisordersDelayed-Action PreparationsOppositional defiantPediatrics Perinatology and Child HealthCore symptomsExtended releasebusinessmedicine.drugJournal of Developmental & Behavioral Pediatrics
researchProduct

Alteraciones del comportamiento. Prevalencia en las consultas de pediatría de atención primaria: Comunidad Valenciana, 2009

2012

Background: Childhood and adolescence mental health needs a proper monitoring. The aim is to estimate behavioral disorders preva- lence in paediatric primary care in the Region of Valencia (Spain) and to describe its distribution according to sex, age and impact areas. Methods: Cross-sectional research. Region of Valencia’s Health Surveillance Network observed along 2009 the behavioral disorders in patients primary health care between 3 and 14 years old. Prevalence and confidence intervals at 95% were calculated. Chi-square test (p<0,05) was calculated to explore the differences in behavioral disorders accor- ding to sex, age and impact areas. Results: Total cases notified were 626. Out of …

Pediatricsmedicine.medical_specialtyAdolescentPopulationPopulation surveillanceEpidemologyPrimary careHealth surveillancePrevalenceMedicineIn patientChildeducationImpact areaSalud MentalVigilancia Epidemiológicaeducation.field_of_studybusiness.industryAtención PrimariaGeneral MedicinePrimary careMental healthConfidence intervalDisorders prevalenceAdolescenciaMental healthInfanciaPrevalenciabusinessRevista Española de Salud Pública
researchProduct