Search results for "inulin"
showing 10 items of 80 documents
Mucoadhesive micelles based on inulin derivative for ocular release of corticosteroids
2016
Die Bedeutung von Topinambur für die Ernährung des Menschen
1951
Aus dem Kot von Erwachsenen, die mit normaler, gemischter Kost ernahrt waren, und von Menschen und Tieren, denen Inulin in Form von Topinambursirup oder Topinamburknollen zugefuhrt worden war, wurden verschiedene Bakterienarten isoliert. Diese Stamme wurden auf ihre Fahigkeit der Inulinspaltung mit der Methode zur Bestimmung reduzierender Substanzen nachHagedorn-Jensen und der manometrischen Methode zur Bestimmung des Gaswechsels nachWarburg untersucht. Als Vergleich dienten die sicher inulinspaltenden Pneumokokken. Alle im normalen Stuhl vorkommenden bzw. untersuchten Keimarten sind weder unter aeroben noch unter bedingt anaeroben Verhaltnissen in der Lage, Inulin abzubauen. Die von uns un…
Fermentation of Jerusalem artichoke by Zymomonas and Saccharomyces
2008
PurposeThe aim of this study is to find out the appropriate fermentation conditions of Jerusalem artichoke powder (JAP) based media to obtain light beverage containing inulin.Design/methodology/approachJAP water suspension or filtrate were used for preparation of growth media with or without enzymatic hydrolysis of inulin for fermentation by Zymomonas mobilis 113 “S” or Saccharomyces cerevisiae.FindingsIf enzymatic hydrolysis of inulin was not used significantly higher amount of inulin (7.42 per cent) was unconverted by Z. mobilis than by S. cerevisiae (2.22 per cent) while the ethanol concentration was much higher (2.86 per cent) after S. cerevisiae fermentation than after Z. mobilis ferme…
Untersuchungen zur Frage des bakteriellen Inulin-Abbaues im menschlichen Darm
1950
Among the bacteria normally occurring in the intestine no races could be demonstrated that were capable of breaking down inuline. Among other bacteria, only pneumococci proved to be capable of breaking down inuline.
Wirkungen von Acetazolamid, Chlorothiazid und Chlormerodrin auf die Clearance von Inulin, echtem endogenen Kreatinin, PAH und Harnstoff. Abgrenzung n…
1959
Blood volume and extracellular space (ECS) of the whole body and some organs of the rat.
1978
Methods are described for estimation of blood volume and extracellular space (ECS) in the whole body and in some organs with 51Cr, 14C-thiocyanate and 3H-inulin. A mean blood volume of 47 ml/kg, a thiocyanate space of 350 ml/kg and a inulin space of 288 ml/kg were determined in the rat. The corresponding values of organs are shown in figures 1--3.
Der Einflu� von Adrenalektomie und Nebennierenrindenhormonen auf die renalen Clearancen von Inulin, p-Aminohippurat, echtem endogenen Kreatinin und H…
1959
Mucoadhesive PEGylated inulin-based self-assembling nanoparticles: In vitro and ex vivo transcorneal permeation enhancement of corticosteroids
2019
Abstract As transcorneal drug delivery is still a challenge, the scope of the present study was to prepare useful nanosystems able to enhance transcorneal permeation/penetration of drugs. Moreover, this work aims to evaluate the effectiveness of inulin-based nanosystems in the specific field of ocular drug delivery and the effect of PEG chains to promote mucoadhesion, stability and transcorneal penetration/permeation enhancer effect of self-assembling nanoparticles in vitro (transwell systems and HCE) and ex vivo (Franz cells and bovine cornea). In particular, inulin was chosen as the starting natural polysaccharide polymer to design a novel amphiphilic derivative named INU-EDA-RA-PEG capab…
MICELLE POLIMERICHE A BASE DI NUOVI DERIVATI ANFIFILICI DELL’INULINA PER LA SOMMINISTRAZIONE OCULARE TOPICA DI CORTICOSTEROIDI NEL TRATTAMENTO DELLE …
2016
Al giorno d’oggi, la via di somministrazione oftalmica costituisce ancora una sfida per i tecnologi farmaceutici. Si tratta, inoltre, probabilmente di uno degli ambiti che più di ogni altro potrebbe beneficiare dello sviluppo di nuovi Drug Delivery Systems basati sull’utilizzo di nanovettori. Infatti, più del 50% delle patologie oculari maggiormente debilitanti (es. degenerazione maculare legata all’età, retinopatia diabetica ed edema maculare diabetico) ha origine a livello del segmento oculare posteriore. Ad oggi, la terapia intravitreale costituisce il gold standard per garantire il raggiungimento del sito target, ovvero la retina. Tuttavia, la necessità di ricorrere a frequenti somminis…
Biotin-Containing Reduced Graphene Oxide-Based Nanosystem as a Multieffect Anticancer Agent: Combining Hyperthermia with Targeted Chemotherapy
2015
Among the relevant properties of graphene derivatives, their ability of acting as an energy-converting device so as to produce heat (i.e., thermoablation and hyperthermia) was more recently taken into account for the treatment of solid tumors. In this pioneering study, for the first time, the in vitro RGO-induced hyperthermia was assessed and combined with the stimuli-sensitive anticancer effect of a biotinylated inulin-doxorubicin conjugate (CJ-PEGBT), hence, getting to a nanosystem endowed with synergic anticancer effects and high specificity. CJ-PEGBT was synthesized by linking pentynoic acid and citraconic acid to inulin. The citraconylamide pendants, used as pH reversible spacer, were …