Search results for "ionit"
showing 10 items of 142 documents
A Retrospective Study of the Proportion of Women at High and Low Risk of Intrauterine Infection Meeting Sepsis Criteria
2021
The Surviving Sepsis Campaign recently recommended that qSOFA not be used as a single parameter for identification of sepsis. Thus, we evaluated the efficacy of SIRS and qSOFA scores in identifying intrauterine infection. This case–control study evaluates SIRS and qSOFA criteria fulfillment in preterm premature rupture of membranes (n = 453)—at high infection risk—versus elective cesarean—at low infection risk (n = 2004); secondary outcomes included intrauterine infection and positive culture rates. At admission, 14.8% of the study group and 4.6% of control met SIRS criteria (p = 0.001), as did 12.5% and 5.5% on post-operation day (POD) 1 (p = 0.001), with no signifi…
Modelling Photoionisation in Isocytosine: Potential Formation of Longer‐Lived Excited State Cations in its Keto Form
2021
Abstract Studying the effects of UV and VUV radiation on non‐canonical DNA/RNA nucleobases allows us to compare how they release excess energy following absorption with respect to their canonical counterparts. This has attracted much research attention in recent years because of its likely influence on the origin of our genetic lexicon in prebiotic times. Here we present a CASSCF and XMS‐CASPT2 theoretical study of the photoionisation of non‐canonical pyrimidine nucleobase isocytosine in both its keto and enol tautomeric forms. We analyse their lowest energy cationic excited states including 2π+ , 2nO+ and 2nN+ and compare these to the corresponding electronic states in cytosine. Investigat…
Extracellular Albumin and Endosomal Ions Prime Enterovirus Particles for Uncoating That Can Be Prevented by Fatty Acid Saturation
2019
ABSTRACT There is limited information about the molecular triggers leading to the uncoating of enteroviruses under physiological conditions. Using real-time spectroscopy and sucrose gradients with radioactively labeled virus, we show at 37°C, the formation of albumin-triggered, metastable uncoating intermediate of echovirus 1 without receptor engagement. This conversion was blocked by saturating the albumin with fatty acids. High potassium but low sodium and calcium concentrations, mimicking the endosomal environment, also induced the formation of a metastable uncoating intermediate of echovirus 1. Together, these factors boosted the formation of the uncoating intermediate, and the infectiv…
Linearly polarized gluons and axial charge fluctuations in the glasma
2018
We calculate of the one- and two-point correlation functions of the energy density and the divergence of the Chern-Simons current in the nonequilibrium Glasma state formed in a high-energy nuclear collision. We show that the latter depends on the difference of the total and linearly polarized gluon transverse momentum distributions. Since the divergence of the Chern-Simons current provides the source of axial charge, we infer information about the statistical properties of axial charge production at early times. We further develop a simple phenomenological model to characterize axial charge distributions in terms of distributions of the energy density.
Boosting background suppression in the NEXT experiment through Richardson-Lucy deconvolution
2021
The NEXT collaboration: et al.
Current Transport Mechanism for Heavy-Ion Degraded SiC MOSFETs
2019
IEEE Transactions on Nuclear Science, 66 (7)
Laser spectroscopy with an electrostatic ConeTrap
2017
A compact electrostatic trap has been designed and installed as part of the recent upgrades to the IGISOL IV facility. The ConeTrap provides an in vacuo optical pumping site for low energy (800 eV) ionic ensembles available for interaction periods of 10-100 ms. At present, 6.7(3) % of injected mass A=98 ions can be trapped, stored for 5 ms, extracted and transported to a laser-ion interaction region. This fraction represents those ions for which no perturbation to total energy or energy spread is observed. Proposed enhancements to the trap are designed to improve the trapping efficiency by up to a factor of 5. Differential pumping and reduction in background pressure below the present 10−6 …
Proton Direct Ionization Upsets at Tens of MeV
2023
Experimental monoenergetic proton single-event upset (SEU) cross sections of a 65-nm low core-voltage static random access memory (SRAM) were found to be exceptionally high not only at low energies ($ 3 MeV and extending up to tens of MeV. The SEU cross Section from 20-MeV protons exceeds the 200-MeV proton SEU cross Section by almost a factor of 3. Similarly, monoenergetic neutron cross sections at 14 MeV are about a factor of 3 lower than the 20-MeV proton cross section. Because of Monte Carlo (MC) simulations, it was determined that this strong enhancement is due to the proton direct ionization process as opposed to the elastic and inelastic scattering processes that dominate the SEU res…
Kinetic Interaction of Cold and Hot Protons With an Oblique EMIC Wave Near the Dayside Reconnecting Magnetopause
2021
STR acknowledges support from the ISSI international team Cold plasma of ionospheric origin in the Earth's magnetosphere and of the Ministry of Economy and Competitiveness (MINECO) of Spain (grant FIS2017-90102-R). Research at IRAP was supported by CNRS, CNES and the University of Toulouse. JHL and DLT acknowledge support from NASA Grant 80NSSC18K1378. RED was supported by NASA grants 80NSSC19K070 and 80NSSC19K0254. MA was supported by SNSA Grant 56/18. SKV and RCA acknowledge support from NASA Grant 80NSSC19K0270. Work performed by MMS team members is supported by NASA contract NNG04EB99C.
Jet quenching as a probe of the initial stages in heavy-ion collisions
2019
Jet quenching provides a very flexible variety of observables which are sensitive to different energy- and time-scales of the strongly interacting matter created in heavy-ion collisions. Exploiting this versatility would make jet quenching an excellent chronometer of the yoctosecond structure of the evolution process. Here we show, for the first time, that a combination of jet quenching observables is sensitive to the initial stages of heavy-ion collisions, when the approach to local thermal equilibrium is expected to happen. Specifically, we find that in order to reproduce at the same time the inclusive particle production suppression, $R_{AA}$, and the high-$p_T$ azimuthal asymmetries, $v…