Search results for "kaksostutkimus"

showing 10 items of 45 documents

Effect of physical activity on health in twins: a 30-yr longitudinal study.

2010

Purpose: The aim of this study was to investigate whether persistent leisure-time physical activity, adjusted for genetic liability and childhood experiences, protects against chronic diseases, early signs of disability, and loss of life satisfaction. Methods: From 5663 healthy adult twin pairs, we identified 146 pairs who were discordant for both intensity and volume of leisure physical activity in 1975 and 1981. Of them, both members of 95 pairs were alive and participated in our follow-up study in 2005 when chronic diseases (such as diabetes, cardiovascular disease, and osteoarthritis), life satisfaction, and disability were assessed by a structured telephone interview. The mean age of t…

GerontologyAdultMalemedicine.medical_specialtyLongitudinal studyPhysical Therapy Sports Therapy and RehabilitationPhysical exercisemorbidityDiseaseType 2 diabetesliikuntaleisure-time physical activityInterviews as TopicDiabetes mellitusInternal medicineSurveys and QuestionnairesOdds RatioTwins DizygoticMedicinesairaudetHealth Status IndicatorsHumansOrthopedics and Sports MedicineGenetic Predisposition to DiseaseLongitudinal Studiestwin-studyExerciseFinlandAgedkaksostutkimusbusiness.industryLife satisfactionOdds ratioTwins MonozygoticMiddle Agedmedicine.diseaseTwin studyChronic DiseaseFemalebusinesschronic diseaseMedicine and science in sports and exercise
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Literacy skills seem to fuel literacy enjoyment, rather than vice versa

2023

Children who like to read and write tend to be better at it. This association is typically interpreted as enjoyment impacting engagement in literacy activities, which boosts literacy skills. We fitted direction-of-causation models to partial data of 3690 Finnish twins aged 12. Literacy skills were rated by the twins' teachers and literacy enjoyment by the twins themselves. A bivariate twin model showed substantial genetic influences on literacy skills (70%) and literacy enjoyment (35%). In both skills and enjoyment, shared-environmental influences explained about 20% in each. The best-fitting direction-of-causation model showed that skills impacted enjoyment, while the influence in the othe…

INTRINSIC MOTIVATIONreading abilitycausalityympäristötekijätCognitive NeuroscienceCHILDRENS MOTIVATIONeducationTWINlapset (ikäryhmät)heritabilitybehavioral disciplines and activitieslukeminenkielellinen kehityslukuharrastusDevelopmental and Educational PsychologyACADEMIC-ACHIEVEMENTREADING-ACHIEVEMENTliteracy skillsASSOCIATIONSkaksostutkimusGENDER-DIFFERENCESSELF-DETERMINATION THEORYENGAGEMENT/dk/atira/pure/sustainabledevelopmentgoals/quality_educationhumanities6122 Literature studieslukutaitoSCHOOLkausaliteettigeneettiset tekijätSDG 4 - Quality Educationprint exposureliteracy enjoyment
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FinnTwin12 Cohort: An Updated Review

2019

AbstractThis review offers an update on research conducted with FinnTwin12 (FT12), the youngest of the three Finnish Twin Cohorts. FT12 was designed as a two-stage study. In the first stage, we conducted multiwave questionnaire research enrolling all eligible twins born in Finland during 1983–1987 along with their biological parents. In stage 2, we intensively studied a subset of these twins with in-school assessments at age 12 and semistructured poly-diagnostic interviews at age 14. At baseline, parents of intensively studied twins were administered the adult version of the interview. Laboratory studies with repeat interviews, neuropsychological tests, and collection of DNA were made of in…

MaleGerontologyTwinsphysical activity030508 substance abuseruokavaliotLongitudinal twin-family studydiverse phenotypes0302 clinical medicinemielenterveysEarly adulthoodgeneticsChildkohorttitutkimusFinlandGenetics (clinical)alcoholNeuropsychologyObstetrics and GynecologytwinsmetabolomicsepigenetiikkaCohorttwo-stage designFemalealkoholinkäyttö0305 other medical sciencePsychologyfyysinen aktiivisuusmental healthAdultAdolescentSubstance-Related Disorderslongitudinal twin-family studyPhysical activitypitkittäistutkimusArticlesmoking03 medical and health sciencestupakointiHumanskaksostutkimusperinnöllisyystiedeepigeneticsMental healthPediatrics Perinatology and Child HealthfenotyyppiGene-Environment InteractionSubstance usedietterveysriskit030217 neurology & neurosurgeryFollow-Up StudiesTwin Research and Human Genetics
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Chronic diseases and objectively monitored physical activity profile among aged individuals – a cross-sectional twin cohort study

2019

Introduction: High physical activity (PA) at old age indicates good functional capacity enabling independent living. We investigated how different disease conditions are associated with measured PA indicators in old women and men, and whether they recognize this association. Materials and methods: This cross-sectional twin cohort study in Finland comprised 779 individuals (276 complete twin pairs, including 117 monozygotic pairs), who participated in hip-worn accelerometer monitoring of PA and responded to questions on diseases and mobility limitations at mean age of 73 (range 71 to 75). Results: Of the participants, 23.2% reported having a disease restricting mobility. With sex and age in …

MaleGerontologyTwinsphysical activitymonitorointiDisease030204 cardiovascular system & hematologyBody Mass IndexCohort Studies0302 clinical medicinesedentary behaviorDisease030212 general & internal medicineta315krooniset tauditFinland2. Zero hungerMobility disabilityexerciseLIMITATIONkuntoliikuntata3141ta3142ASSOCIATIONGeneral MedicineSedentary behavior3142 Public health care science environmental and occupational healthTIME3. Good healthOBESITYOriginal ArticleFemaleIndependent Livingfyysinen aktiivisuusikääntyneetCohort studyEXERCISE THERAPYPhysical activityMOBILITY DISABILITY03 medical and health sciencesmedicineHumansMobility LimitationOLDER-ADULTSMETAANALYSISAgedMonitoring Physiologickaksostutkimusdiseasebusiness.industryta1184MORTALITYExercise therapymedicine.diseaseObesityta3124LIFEmonitoringCross-Sectional Studieslimitation of activityChronic DiseasetwinSelf ReportbusinessIndependent livingAnnals of Medicine
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Long-term leisure-time physical activity and other health habits as predictors of objectively monitored late-life physical activity – A 40-year twin …

2018

AbstractIMPORTANCEModerate-to-vigorous physical activity (MVPA) in old age is an important indicator of good health and functional capacity enabling independent living.OBJECTIVETo investigate whether physical activity and other health habits at ages 31-48 years predict objectively measured MVPA decades later.DESIGN, SETTING, AND PARTICIPANTSThis prospective twin cohort study in Finland comprised 616 individuals (197 complete twin pairs, including 91 monozygotic pairs, born 1940-1944), who responded to baseline questionnaires in 1975, 1981, and 1990, and participated in accelerometer monitoring at follow-up (mean age, 73 years).EXPOSURESPrimary exposure was long-term leisure-time physical ac…

MaleMultivariate statisticsFITNESSMonozygotic twinphysical activitylcsh:MedicineDETERMINANTS030204 cardiovascular system & hematologyOverweightCohort StudiesCorrelationHabits0302 clinical medicineEpidemiologyMedicineProspective Studies030212 general & internal medicinelcsh:Sciencetwin stydy2. Zero hungerMultidisciplinarySEDENTARY BEHAVIORRegression analysisMiddle Agedleisure-time3142 Public health care science environmental and occupational healthFemalemedicine.symptomHealth habitsvapaa-aikafyysinen aktiivisuusCohort studymedicine.medical_specialtyPhysical activityArticleSTYLE03 medical and health sciencesLeisure ActivitiesHumansOLDER-ADULTSExerciseSocioeconomic statusAgedMonitoring Physiologickaksostutkimusbusiness.industryDISABILITYMORTALITYlcsh:Rhealth habits030229 sport sciencesTwin studykaksosetpredictorsMOBILITYterveyskäyttäytyminenMultivariate AnalysisRISK-FACTORSlcsh:QFOLLOW-UPbusinessBody mass indexIndependent livingDemographyScientific Reports
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Genetics of Perceived Family Interaction From 12 to 17 Years of Age

2019

We analyzed how the effects of genetic and environmental factors on the perceptions of family interaction change from early to late adolescence. The data were collected by postal surveys on Finnish twins (N = 4808) at 12, 14 and 17 years of age and analyzed using genetic twin modeling. Additive genetic factors explained a modest share of the variation in perceived relational support (a2 = 0.30 in boys and 0.18 in girls) and relational tensions (a2 = 0.13 and 0.14, respectively) at 12 years of age, with the proportions becoming larger through 17 years of age (a2 = 0.53 in boys and 0.49 in girls for relational support; a2 = 0.35 in boys and 0.33 in girls for relational tensions). Simultaneous…

MaleParents0301 basic medicineCHILDHOODTwinsADULTHOODsosiaalinen vuorovaikutusAdolescentsDevelopmental psychology0302 clinical medicinenuoretSurveys and QuestionnairesTwins DizygoticadolescentsChildFinlandGenetics (clinical)media_commonOriginal ResearchHERITABILITYAge Factors1184 Genetics developmental biology physiologyLate adolescence3142 Public health care science environmental and occupational healthETIOLOGYHealth psychologyVariation (linguistics)perhesuhteetADOLESCENCE5141 SociologyFemaleFamily Relationsgeneettiset tekijätPsychologymedicine.medical_specialtyAdolescentmedia_common.quotation_subjectEnvironmentBEHAVIORSFamily interactionENVIRONMENTAL-INFLUENCES03 medical and health sciencesSex FactorsPerceptionmedicineGeneticsHumansFamilyEcology Evolution Behavior and SystematicskaksostutkimusperinnöllisyystiedePublic healthCorrectionTwins MonozygoticHeritabilityfamily interactionkaksosetBODY-MASS INDEX030104 developmental biologyEtiologyGene-Environment InteractionPerceptionBody mass index030217 neurology & neurosurgeryBehavior Genetics
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Motives for physical activity in older men and women : A twin study using accelerometer-measured physical activity

2019

Motives for physical activity may vary considerably by age, sex, and the level of physical activity. We aimed to examine motives for physical activity in older men and women with different physical activity levels as well as whether genetic and/or environmental factors explain those motives. Finnish twins (mean age 72.9 years, 262 full twin pairs) self-reported their motives for physical activity. Time spent on moderate-to-vigorous physical activity was monitored using a hip-worn accelerometer. Comparisons between the different physical activity groups of older twins (n = 764-791/motive dimension) were analyzed using the Wald test, and effect sizes were calculated as Cohen's d. Quantitative…

MalePhysical fitnessPhysical activityPsychological interventionPhysical Therapy Sports Therapy and Rehabilitation030204 cardiovascular system & hematology03 medical and health sciencesSex Factors0302 clinical medicineAGEmotivationPEOPLEaged individualsAccelerometryGenetic modelingHumansOrthopedics and Sports Medicine315 Sport and fitness sciencesAgedmotivaatiokaksostutkimusdevice‐measured physical activityexerciseBARRIERSkuntoliikuntabusiness.industrykiihtyvyysmittaritMean ageexercise motivation030229 sport sciencestwinsTwin study3142 Public health care science environmental and occupational healthdevice-measured physical activity3141 Health care scienceMOTIVATORSHealth maintenanceFemalebusinessPsychologyikääntyneetfyysinen aktiivisuusClinical psychology
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Fat oxidation at rest and during exercise in male monozygotic twins

2019

Abstract Purpose We aimed to investigate if hereditary factors, leisure-time physical activity (LTPA) and metabolic health interact with resting fat oxidation (RFO) and peak fat oxidation (PFO) during ergometer cycling. Methods We recruited 23 male monozygotic twin pairs (aged 32–37 years) and determined their RFO and PFO with indirect calorimetry for 21 and 19 twin pairs and for 43 and 41 twin individuals, respectively. Using physical activity interviews and the Baecke questionnaire, we identified 10 twin pairs as LTPA discordant for the past 3 years. Of the twin pairs, 8 pairs participated in both RFO and PFO measurements, and 2 pairs participated in either of the measurements. We quantif…

MaleSports medicinePhysiologyIntraclass correlationTwinsMonozygotic twinDETERMINANTSlipiditliikuntaglukoosiFats0302 clinical medicineFat oxidationlipid metabolismSUBSTRATE OXIDATIONOrthopedics and Sports MedicineOral glucose tolerance315 Sport and fitness sciencesaineenvaihduntaAdiposityexerciseINSULIN SENSITIVITYhapettuminenArea under the curve1184 Genetics developmental biology physiologytwinsGeneral MedicineVARIABILITYCardiologyOriginal ArticleOxidation-Reductionfyysinen aktiivisuusAdultmedicine.medical_specialtyRest030209 endocrinology & metabolismMotor ActivityDIETARY-FATCAPACITYYoung Adult03 medical and health sciencesTIME PHYSICAL-ACTIVITYPhysiology (medical)Internal medicineCARBOHYDRATEmedicineHumansExerciseOral glucose toleranceMetabolic healthkaksostutkimusbusiness.industryINTENSITYPublic Health Environmental and Occupational HealthCalorimetry IndirectTwins Monozygotic030229 sport sciencesGlucose Tolerance TestConfidence intervalLipid metabolismoral glucose toleranceYOUNGbusiness
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Sport disciplines, types of sports, and waist circumference in young adulthood – a population-based twin study

2017

Purpose: The benefits of physical activity (PA) in preventing abdominal obesity are well recognized, but the role of different sport disciplines remains open. We aimed, therefore, to investigate how participation in different sport disciplines, and the number and types of sports engaged in are associated with waist circumference (WC) in young adulthood. Methods: This population-based cohort study comprised 4027 Finnish twin individuals (1874 men), with a mean age of 34 y (32-37), who answered a survey, including self-measured WC. We extracted the number and identified the types (aerobic, power, and mixed) of the different sport disciplines respondents reported participating in. Results: The…

MaleliikuntaCohort Studies0302 clinical medicineOrthopedics and Sports Medicine030212 general & internal medicinetwin study315 Sport and fitness sciencesYoung adultta315Abdominal obesityRISKeducation.field_of_studyta3141General Medicinewaist circumference3142 Public health care science environmental and occupational healthsport disciplinesWEIGHT-GAINVISCERAL FATADOLESCENCEFemaleHEALTHmedicine.symptomfyysinen aktiivisuusSportsCohort studyAdultCOUNTRIESmedicine.medical_specialtyWaistDizygotic twinPopulationEXERCISE030209 endocrinology & metabolismPhysical Therapy Sports Therapy and Rehabilitationabdominal obesityTIME PHYSICAL-ACTIVITY03 medical and health sciencesmedicineHumanseducationkaksostutkimusPhysical activitybusiness.industryTwin studyBODY-MASS INDEXPhysical therapybusinesshuman activitiesBody mass indexDemographyEuropean Journal of Sport Science
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Early-onset tobacco use and suicide-related behavior – A prospective study from adolescence to young adulthood

2018

Abstract Background Developmental relationships between tobacco use and suicide-related behaviors (SRB) remain unclear. Our objective was to investigate the longitudinal associations of tobacco use in adolescence and SRB in adulthood. Methods Using a prospective design, we examined whether tobacco use in adolescence is associated with SRB (intentional self-injury, suicide ideation) in young adulthood in a population-based sample of 1330 twins (626 males, 704 females). The baseline and follow-up data were collected by professionally administered semi-structured poly-diagnostic interviews at ages 14 and 22, respectively. Results After adjusting for multiple potential confounders, those who re…

Maleself-injuryMedicine (miscellaneous)Suicide AttemptedToxicologytobaccoTobacco Use0302 clinical medicineOdds RatioLongitudinal StudiesProspective Studies030212 general & internal medicineAge of OnsetYoung adultProspective cohort studySuicidal ideationta515FinlanditsetuhokäyttäytyminenEarly onseteducation.field_of_studyDELIBERATE SELF-HARMConfoundingtwins3142 Public health care science environmental and occupational healthPsychiatry and Mental healthClinical PsychologyCohortitsemurhaFemalemedicine.symptomAdolescent515 PsychologytupakkaPopulationQUESTIONNAIREsmokingArticleCigarette SmokingSuicidal IdeationYoung Adult03 medical and health sciencesSex FactorstupakointimedicineHumansCOHORTIDEATIONeducationSUBSTANCE USEkaksostutkimusbusiness.industryMAJOR DEPRESSIONOdds ratio030227 psychiatrysuicidal ideationkaksosetRISK-FACTORSCOMMUNITY SAMPLECIGARETTE-SMOKINGFOLLOW-UPbusinessSelf-Injurious BehaviorDemographyAddictive Behaviors
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