Search results for "lcsh:TK1-9971"
showing 10 items of 157 documents
The Histone Deacetylase Inhibitor JAHA Down-Regulates pERK and Global DNA Methylation in MDA-MB231 Breast Cancer Cells
2015
The histone deacetylase inhibitor N-1-(ferrocenyl)-N-8-hydroxyoctanediamide (JAHA) down-regulates extracellular-signal-regulated kinase (ERK) and its activated form in triple-negative MDA-MB231 breast cancer cells after 18 h and up to 30 h of treatment, and to a lesser extent AKT and phospho-AKT after 30 h and up to 48 h of treatment. Also, DNA methyltransferase 1 (DNMT1), 3b and, to a lesser extent, 3a, downstream ERK targets, were down-regulated already at 18 h with an increase up to 48 h of exposure. Methylation-sensitive restriction arbitrarily-primed (MeSAP) polymerase chain reaction (PCR) analysis confirmed the ability of JAHA to induce genome-wide DNA hypomethylation at 48 h of expos…
In Vitro Evaluation of the Biological Effects of ACTIVA Kids BioACTIVE Restorative, Ionolux, and Riva Light Cure on Human Dental Pulp Stem Cells
2019
This study aimed to analyze the biological effects of three new bioactive materials on cell survival, migration, morphology, and attachment in vitro. ACTIVA Kids BioACTIVE Restorative (Pulpdent, Watertown, MA, USA) (Activa), Ionolux (Voco, Cuxhaven, Germany), and Riva Light Cure UV (SDI, Bayswater, Australia) (Riva) were handled and conditioned with a serum-free culture medium. Stem cells from human dental pulp (hDPSCs) were exposed to material extracts, and metabolic activity, cell migration, and cell morphology were evaluated. Cell adhesion to the different materials was analyzed by scanning electron microscopy (SEM). The chemical composition of the materials was evaluated by energy-dispe…
A Coupled Fixed Point Theorem in Fuzzy Metric Space Satisfying ϕ-Contractive Condition
2013
The intent of this paper is to prove a coupled fixed point theorem for two pairs of compatible and subsequentially continuous (alternately subcompatible and reciprocally continuous) mappings, satisfyingϕ-contractive conditions in a fuzzy metric space. We also furnish some illustrative examples to support our results.
The influence of building interactions on seismic and elastic body waves
2019
We outline some recent research advances on the control of elastic waves in thin and thick plates, that have occurred since the large scale experiment [S. Brûlé, Phys. Rev. Lett. 112, 133901 (2014)] that demonstrated significant interaction of surface seismic waves with holes structuring sedimentary soils at the meter scale. We further investigate the seismic wave trajectories of compressional body waves in soils structured with buildings. A significant substitution of soils by inclusions, acting as foundations, raises the question of the effective dynamic properties of these structured soils. Buildings, in the case of perfect elastic conditions for both soil and buildings, are shown to int…
PV Reconfiguration Systems: a Technical and Economic Study
2017
Dynamical electrical array reconfiguration strategies for grid-connected PV systems have been proposed as solution to improve energy production due to the mismatch effect of PV plants during partial shading conditions. Strategies are based on the use of dynamic connections between PV panels given by the employment of switches that allow for each panel the series, parallel or exclusion connections, physically changing the electrical connections between the related PV modules, consequentially modifying the layout of the plant. Usually the cost of the dynamic matrix is not taken into account. This novel work evaluates the economic advantages obtained by the use of reconfiguration strategies in…
New Microbe Killers: Self-Assembled Silver(I) Coordination Polymers Driven by a Cagelike Aminophosphine
2019
New Ag(I) coordination polymers, formulated as [Ag(µ
Analysis of Energy Consumption Performance towards Optimal Radioplanning of Wireless Sensor Networks in Heterogeneous Indoor Environments
2014
In this paper the impact of complex indoor environment in the deployment and energy consumption of a wireless sensor network infrastructure is analyzed. The variable nature of the radio channel is analyzed by means of deterministic in-house 3D ray launching simulation of an indoor scenario, in which wireless sensors, based on an in-house CyFi implementation, typically used for environmental monitoring, are located. Received signal power and current consumption measurement results of the in-house designed wireless motes have been obtained, stating that adequate consideration of the network topology and morphology lead to optimal performance and power consumption reduction. The use of radiopl…
Recovery Capabilities of Rateless Codes on Simulated Turbulent Terrestrial Free Space Optics Channel Model
2013
Free Space Optics (FSO) links are affected by several impairments: optical turbulence, scattering, absorption, and pointing. In particular, atmospheric optical turbulence generates optical power fluctuations at the receiver that can degrade communications with fading events, especially in high data rate links. Innovative solutions require an improvement of FSO link performances, together with testing models and appropriate channel codes. In this paper, we describe a high-resolution time-correlated channel model able to predict random temporal fluctuations of optical signal irradiance caused by optical turbulence. Concerning the same channel, we also report simulation results on the error mi…
GA-based Off-Line Parameter Estimation of the Induction Motor Model Including Magnetic Saturation and Iron Losses
2020
This paper, starting from recent papers in the scientific literature dealing with Rotating Induction Motor (RIM) dynamic modelling, as a first step, improves its space-vector dynamic model, including both the magnetic saturation and iron losses; The main original aspects of the proposed model are the following: 1) the magnetic saturation of the iron core has been described on the basis of both current versus flux and flux versus current functions, 3) it includes the iron losses, separating them in hysteresis and eddy current ones, 4) it includes the effect of the load on the magnetic saturation. Afterwards, it proposes an off-line technique for the estimation of electrical parameters of thi…
Decay Heat Removal and Transient Analysis in Accidental Conditions in the EFIT Reactor
2008
The development of a conceptual design of an industrial-scale transmutation facility (EFIT) of several 100 MW thermal power based on accelerator-driven system (ADS) is addressed in the frame of the European EUROTRANS Integral Project. In normal operation, the core power of EFIT reactor is removed through steam generators by four secondary loops fed by water. A safety-related decay heat removal (DHR) system provided with four independent inherently safe loops is installed in the primary vessel to remove the decay heat by natural convection circulation under accidental conditions which are caused by a loss-of-heat sink (LOHS). In order to confirm the adequacy of the adopted solution for decay…