Search results for "lean body mass"

showing 10 items of 109 documents

Plantarflexor Muscle-Tendon Properties are Associated With Mobility in Healthy Older Adults

2015

BACKGROUND: Muscle mass, strength, and power are known determinants of mobility in older adults but there is limited knowledge on the influence of muscle architecture or tendon properties on mobility. The purpose of this study was to examine the relationship between mobility and plantarflexor muscle-tendon properties in healthy older adults.METHODS: A total of 52 subjects (age 70-81 years) were measured for 6-minute walk test (6MWT), timed "up and go"-test (TUG), isometric plantarflexion strength, Achilles tendon stiffness, triceps surae muscle architecture, lower extremity lean mass, isometric leg extension strength, and leg extension power. Partial correlations and multivariate regression…

MaleAgingTendon stiffnesstendonmuscleIsometric exerciseWalkingPhysical performanceTendonsTriceps surae muscleMedicineta315Gait BiomechanicsAchilles tendonta3141SkeletalTendonmedicine.anatomical_structureMuscleFemalemedicine.medical_specialtyGastrocnemius muscleSkeletal/physiologycross-sectional studyMuscle architectureHumanshumanMuscle Strengthskeletal muscleMuscle SkeletalAgedbusiness.industrytendon stiffnessaged; aging; cross-sectional study; female; human; male; muscle strength; physiology; skeletal muscle; tendon; walking Aged; Aging; Cross-Sectional Studies; Female; Humans; Male; Muscle Strength; Muscle Skeletal; Tendons; Walking; Gait Biomechanics; Muscle; Muscle architecture; Physical performance; Tendon stiffnessphysical performancegait biomechanicsAging/physiologybody regionsMuscle Skeletal/physiologyCross-Sectional Studiesmuscle architecturephysiologyPhysical therapyLean body massFascicle lengthGeriatrics and GerontologybusinessMuscle architecturehuman activitiesTendons/physiologyJournals of Gerontology. Series A: Biological Sciences & Medical Sciences
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Physical function and lean body mass as predictors of bone loss after hip fracture: a prospective follow-up study

2020

Abstract Background: Predictors of bone deterioration after hip fracture have not been well characterized. The aim of this study was to examine the associations of physical function and lean body mass (LBM) with loss of bone density and strength in older people recovering from a hip fracture. Methods: A total of 81 over 60-year-old, community-dwelling men and women operated for a hip fracture participated in this 1-year prospective follow-up study. Distal tibia total volumetric bone mineral density (vBMDTOT, mg/cm³) and compressive strength index (BSI, g²/cm⁴) and mid-tibia cortical vBMD (vBMDCO, mg/cm³) and bending strength index (SSI, mm³) were assessed in both legs by peripheral quantita…

MaleAginglcsh:Diseases of the musculoskeletal systemfyysinen toimintakykyluuntiheysWalkingHip fracturemurtumatBone DensityBone mineral densityHumansProspective StudiespQCTAgedAged 80 and overTibiaHip FracturesMiddle AgedPhysical Functional PerformancelonkkaBone Diseases MetabolicikääntyminenlihasmassaLean body massMultivariate AnalysisBody CompositionLinear ModelsPhysical functionFemaleIndependent Livinglcsh:RC925-935human activitiesResearch ArticleFollow-Up StudiesBMC Musculoskeletal Disorders
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Functional Inactivation of the Genome-Wide Association Study Obesity Gene Neuronal Growth Regulator 1 in Mice Causes a Body Mass Phenotype

2012

To date, genome-wide association studies (GWAS) have identified at least 32 novel loci for obesity and body mass-related traits. However, the causal genetic variant and molecular mechanisms of specific susceptibility genes in relation to obesity are yet to be fully confirmed and characterised. Here, we examined whether the candidate gene NEGR1 encoding the neuronal growth regulator 1, also termed neurotractin or Kilon, accounts for the obesity association. To characterise the function of NEGR1 for body weight control in vivo, we generated two novel mutant mouse lines, including a constitutive NEGR1-deficient mouse line as well as an ENU-mutagenised line carrying a loss-of-function mutation …

MaleCandidate geneMutantlcsh:MedicineGenome-wide association studymedicine.disease_causeEndoplasmic ReticulumEatingGene Knockout TechniquesMice0302 clinical medicineEndocrinologylcsh:ScienceObesity; NEGR1; GWAS; body weight control2. Zero hungerGenetics0303 health sciencesMutationMultidisciplinaryNeuronal growth regulator 1GenomicsPhenotypePhenotypeMedicineFemaleFunction and Dysfunction of the Nervous SystemResearch ArticleGenotypeHypothalamusNerve Tissue ProteinsBiologyMotor ActivityDiet High-FatCell Line03 medical and health sciencesGenetic MutationGenome Analysis ToolsmedicineGeneticsGenome-Wide Association StudiesCell AdhesionNeuritesAnimalsHumansObesityGene SilencingGeneBiologyAlleles030304 developmental biologyNutritionlcsh:RBody WeightMembrane ProteinsHuman GeneticsNeuroendocrinologyBody HeightMetabolic DisordersGenetics of DiseaseLean body masslcsh:QEnergy Metabolism030217 neurology & neurosurgeryGenome-Wide Association StudyPLoS ONE
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Effects of a weight management program delivered by social media on weight and metabolic syndrome risk factors in overweight and obese adults: A rand…

2017

Author(s): Jane, Monica; Hagger, Martin; Foster, Jonathan; Ho, Suleen; Kane, Robert; Pal, Sebely | Abstract: IntroductionThe aim of this project was to evaluate the effectiveness of using social media to augment the delivery of, and provide support for, a weight management program delivered to overweight and obese individuals during a twenty four week intervention.MethodsParticipants randomly divided into either one of two intervention groups or a control group. The two intervention groups were instructed to follow identical weight-management program. One group received the program within a Facebook group, along with a support network with the group, and the other intervention group receive…

MaleFacebookPGHealth Behaviorphysical activitySocial ScienceslipiditCardiovascularweight controlravitsemussuosituksetBiochemistrylaw.inventionBody Mass Index0302 clinical medicine7.1 Individual care needsSociologyWeight managementPublic and Occupational Healthlcsh:Sciencemetabolinen oireyhtymäta515Cancerblood pressureSocial Communicationylipainota3141LipidsWaist CircumferenceNetwork Analysisinsulinmedicine.medical_specialtyClinical Trials and Supportive Activitiesinsuliini03 medical and health sciencesSocial supportClinical ResearchHumansvertaisryhmätExerciseLife Styledietary guidelines6.7 Physicalpamphlet groupPreventionlcsh:RBiology and Life SciencesSocial SupportPhysical Activitymedicine.diseaseObesityCommunicationsverenpainelcsh:QManagement of diseases and conditionsBody mass indexSocial MediaPhysiologylcsh:MedicineOverweightOral and gastrointestinalFatsRandomized controlled trialWeight losslawBehavior TherapyRisk FactorsMedicine and Health Sciencesblood glucose030212 general & internal medicinepainoindeksita315Metabolic SyndromeMultidisciplinaryCGMiddle AgedStrokeSelf-Help GroupsTreatment OutcomeSocial NetworksPhysiological ParametersFemalemedicine.symptomResearch ArticleAdultComputer and Information SciencesGeneral Science & Technologysosiaalinen media030209 endocrinology & metabolismpainonhallintaBMIBehavioral and Social ScienceWeight LossmedicineObesityMetabolic and endocrineNutritionpeer groupsbusiness.industryBody WeightEvaluation of treatments and therapeutic interventionsOverweightDietLean body massPhysical therapybusinessPLoS ONE
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Accelerometer-assessed sedentary work, leisure time and cardio-metabolic biomarkers during one year : Effectiveness of a cluster randomized controlle…

2017

BackgroundIt is unknown whether reducing sedentary time at work and during leisure time is possible and effective during one year.MethodsOffice workers with young children were recruited for this one-year cluster-randomized controlled trial through kindergartens and primary schools from 7 clusters in the city of Jyväskylä, Finland. After a lecture, face-to-face tailored counseling was used to set contractually binding goals regarding reducing and breaking up sitting periods and increasing light intensity physical activity during work and leisure time. Primary outcomes of total, work and leisure sedentary time (ResultsParticipants from intervention (N = 71) and control (N = 62) regions were …

MaleParentscardio-metabolic biomarkersLeisure timeSocial Sciencessedentary workbiomarkkeritCardiovascular SystemBiochemistrylaw.invention0302 clinical medicineRandomized controlled trialSociologylawMedicine and Health SciencesCluster AnalysisPublic and Occupational Health030212 general & internal medicineta315Musculoskeletal SystemMultidisciplinaryQRta3142vanhemmatLecturesEngineering and TechnologyLegsMedicineFemaleAnatomyBehavioral and Social Aspects of Healthfyysinen aktiivisuusvapaa-aikaResearch ArticleAdultmedicine.medical_specialtyScienceAccelerationSittingEducation03 medical and health sciencesmedicineHumansistumatyöOccupationsSedentary lifestyleNutritionBehaviorbusiness.industryWork (physics)Limbs (Anatomy)Biology and Life Sciences030229 sport sciencesPhysical ActivityAnthropometryDietleisure timeLight intensitymarkkeritLean body massPhysical therapyRecreationSedentary BehaviorElectronicsAccelerometersbusinessBiomarkers
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Efficacy of a cognitive and behavioral treatment for childhood obesity supported by the ETIOBE web platform

2019

Recently, the prevalence of childhood obesity has increased alar- mingly. Interventions combining eating habits, physical activity (PA), behavioral components, and family support have been shown to be effective, although variables such as self-efficacy beliefs and motivation seem to be important in achieving stable changes. Information and communication technologies (ICTs) can provide additional resources to traditional treatments. The objective is to analyze the efficacy of two treatments: a cognitive and behavioral treatment (CBT) focused on the promotion of healthy eating and PA habits, and this CBT intervention supported by a web platform (ETIOBE). Forty-seven obese children were random…

MalePediatric ObesityMediation (statistics)Family supportPsychological interventionHealth Promotioninformation and communication technologiesChildhood obesity03 medical and health sciences0302 clinical medicineIntervention (counseling)medicineHumansChildhood obesity030212 general & internal medicineChildApplied PsychologyInternetCognitive Behavioral Therapybusiness.industryCognitionmedicine.diseaseSelf Efficacy030227 psychiatryPsychiatry and Mental healthClinical Psychologycognitive and behavioral treatmentTreatment OutcomeLean body massFemaleAnalysis of varianceweb- supported interventionsbusinessClinical psychologyPsychology, Health & Medicine
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Nutritional Status of Maintenance Dialysis Patients: Low Lean Body Mass Index and Obesity Are Common, Protein-Energy Wasting Is Uncommon.

2016

Background and Aims Maintenance dialysis patients are at increased risk of abnormal nutritional status due to numerous causative factors, both nutritional and non-nutritional. The present study assessed the current prevalence of protein-energy wasting, low lean body mass index and obesity in maintenance dialysis patients, and compared different methods of nutritional assessment. Methods In a cross-sectional study conducted in 2014 at Roskilde Hospital, Denmark, we performed anthropometry (body weight, skinfolds, mid-arm, waist, and hip circumferences), and determined plasma albumin and normalized protein catabolic rate in order to assess the prevalence of protein-energy wasting, low lean bo…

MalePediatricsProtein–energy malnutritionPhysiologyCross-sectional study030232 urology & nephrologySocial Scienceslcsh:Medicine030204 cardiovascular system & hematologyBiochemistryBody Mass IndexFats0302 clinical medicinePrevalenceMedicine and Health SciencesYoung adultlcsh:ScienceWastingAged 80 and overMultidisciplinaryAnthropometryMiddle AgedLipidsPhysiological ParametersNephrologyPhysical SciencesBody CompositionEngineering and TechnologyFemalePhysical AnthropologyWaist Circumferencemedicine.symptomResearch ArticleAdultmedicine.medical_specialtyMaterials ScienceNutritional StatusFuelsProtein-Energy MalnutritionYoung Adult03 medical and health sciencesRenal DialysisAlbuminsInternal medicineMedical DialysismedicineHumansObesityMaterials by AttributeAgedNutritionbusiness.industryBody Weightlcsh:RBiology and Life SciencesProteinsAnthropometrymedicine.diseaseObesityEnergy and PowerCross-Sectional StudiesEndocrinologyAnthropologyLean body massKidney Failure Chroniclcsh:QbusinessBody mass indexPLoS ONE
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Validation of two portable bioelectrical impedance analyses for the assessment of body composition in school age children

2017

Background Bioelectrical impedance analysis (BIA) is a convenient and child-friendly method for longitudinal analysis of changes in body composition. However, most validation studies of BIA have been performed on adult Caucasians. The present cross-sectional study investigated the validity of two portable BIA devices, the Inbody 230 (BIA8MF) and the Tanita BC-418 (BIA8SF), in healthy Taiwanese children. Methods Children aged 7–12 years (72 boys and 78 girls) were recruited. Body composition was measured by the BIA8SF and the BIA8MF. Dual X-ray absorptiometry (DXA) was used as the reference method. Results There were strong linear correlations in body composition measurements between the BIA…

MalePediatricsResearch ValidityCross-sectional studylcsh:MedicinePediatricsDiagnostic RadiologyFamilies0302 clinical medicineMathematical and Statistical TechniquesAbsorptiometry PhotonMedicine and Health SciencesElectric ImpedanceMedicine030212 general & internal medicinelcsh:ScienceChildChildrenMusculoskeletal SystemMultidisciplinarySchool age childRadiology and ImagingLimits of agreementResearch AssessmentArmsConcordance correlation coefficientArticle-Level MetricsAdipose TissuePhysical SciencesBody CompositionRegression AnalysisFemaleAnatomyBioelectrical impedance analysisStatistics (Mathematics)Research Articlemedicine.medical_specialtyImaging Techniques030209 endocrinology & metabolismLinear Regression AnalysisResearch and Analysis MethodsFat mass03 medical and health sciencesDiagnostic MedicineLinear regressionHumansAbsorptiometryStatistical MethodsAltmetricsbusiness.industrylcsh:RLimbs (Anatomy)Biology and Life SciencesReproducibility of ResultsBiological TissueCross-Sectional StudiesAge GroupsPeople and PlacesLean body masslcsh:QPopulation GroupingsbusinessNuclear medicineMathematicsPLoS ONE
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Weight Gain Composition in Preterm Infants with Dual Energy X-Ray Absorptiometry

2001

Whole body composition was investigated using dual energy x-ray absorptiometry in 54 healthy preterm infants, birth weight < 1750 g, who were fed fortified human milk (n = 20) and preterm formula (n = 34) when full enteral feeding was attained and then again 3 wk later at around the time of discharge. Weight gain composition was calculated from the difference between the earlier and later measurement. The minimal detectable changes in whole body composition over time according to the variance of the population (within groups of 20 infants) and the minimal detectable changes according to the dietary intervention (between two groups of 20 infants) were determined at 5% significance and 80% po…

MalePediatricsmedicine.medical_specialtyBirth weightPopulationWeight GainEnteral administrationWhole body compositionAbsorptiometry PhotonAnimal sciencemedicineHumansLongitudinal StudieseducationDual-energy X-ray absorptiometryeducation.field_of_studymedicine.diagnostic_testChemistryInfant NewbornPediatrics Perinatology and Child HealthBody CompositionLean body massFemaleComposition (visual arts)medicine.symptomWeight gainInfant PrematurePediatric Research
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Possible Reduction of Cardiac Risk after Supplementation with Epigallocatechin Gallate and Increase of Ketone Bodies in the Blood in Patients with Mu…

2020

Multiple sclerosis (MS) is a neurodegenerative disease that causes anthropometric changes characterised by functional disability, increase in fat mass, and decrease in lean mass. All these variables are related to a greater cardiac risk. The polyphenol epigallocatechin gallate (EGCG) and an increase in ketone bodies in the blood have been shown to have beneficial effects on anthropometric and biochemical variables related to cardiovascular activity. The aim of this study was to analyse the impact of the intervention with EGCG and ketone bodies on cardiac risk in MS patients. A population of 51 MS patients were randomly assigned to a control group and an intervention group (daily dose of 800…

MalePilot ProjectsKetone Bodies030204 cardiovascular system & hematologyEpigallocatechin gallatemultiple sclerosisCatechinBody Mass Indexchemistry.chemical_compound0302 clinical medicineFunctional abilityeducation.field_of_studyNutrition and Dieteticsbiology3-Hydroxybutyric AcidAnthropometryfood and beveragesMiddle AgedPON1C-Reactive ProteinTreatment OutcomeCardiovascular DiseasesKetone bodiesFemalelcsh:Nutrition. Foods and food supplyAdultmedicine.medical_specialtycardiac riskepigallocatechin gallateWaistCardiotonic AgentsMultiple SclerosisPopulationlcsh:TX341-641Article03 medical and health sciencesInternal medicinemedicineHumanseducationSerum AlbuminAnalysis of VarianceWaist-Height Ratiobusiness.industryAryldialkylphosphataseParaoxonaseEndocrinologychemistryHeart Disease Risk FactorsDietary Supplementsketone bodiesLean body massbiology.proteinbusiness030217 neurology & neurosurgeryFood Science
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