Search results for "leave"

showing 10 items of 372 documents

Polyoxygenated Cyclohexenes and Other Constituents of Cleistochlamys kirkii Leaves.

2016

Thirteen new metabolites, including the polyoxygenated cyclohexene derivatives cleistodiendiol (1), cleistodienol B (3), cleistenechlorohydrins A (4) and B (5), cleistenediols A-F (6-11), cleistenonal (12), and the butenolide cleistanolate (13), 2,5-dihydroxybenzyl benzoate (cleistophenolide, 14), and eight known compounds (2, 15-21) were isolated from a MeOH extract of the leaves of Cleistochlamys kirkii. The purified metabolites were identified by NMR spectroscopic and mass spectrometric analyses, whereas the absolute configurations of compounds 1, 17, and 19 were established by single-crystal X-ray diffraction. The configuration of the exocyclic double bond of compound 2 was revised base…

Double bondStereochemistryCyclohexenesPlasmodium falciparumCyclohexenePharmaceutical ScienceBreast Neoplasms01 natural sciencesAnalytical Chemistrychemistry.chemical_compoundAntimalarialsInhibitory Concentration 50X-Ray DiffractionDrug DiscoveryCyclohexenesHumansta116metabolitesCleistochlamys kirkiiButenolidePharmacologychemistry.chemical_classificationMolecular Structure010405 organic chemistryOrganic Chemistryspectrometric analysesMass spectrometricAntineoplastic Agents Phytogenic3. Good health0104 chemical sciencesPlant Leaves010404 medicinal & biomolecular chemistryCleistophenolideHEK293 CellsComplementary and alternative medicinechemistryMolecular MedicineJournal of natural products
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Evaluation of the Fermentation Dynamics of Commercial Baker’s Yeast in Presence of Pistachio Powder to Produce Lysine-Enriched Breads

2019

The present work was carried out to evaluate the microbiological, physicochemical, and sensory characteristics of fortified pistachio breads. Pistachio powder (5% w/w) was added to flour or semolina and fermented by a commercial baker’s yeast (Saccharomyces cerevisiae). Pistachio powder did not influence the biological leavening of the doughs. The kinetics of pH and total titratable acidity (TTA) during dough fermentation showed that the leavening process occurred similarly for all trials. The concentration of yeasts increased during fermentation and reached levels of 108 CFU/g after 2 h. Pistachio powder decreased the height and softness of the final breads and increased cell density…

Dough fermentationlcsh:TP500-660lysinebiologyChemistrybiological leaveningdigestive oral and skin physiologyLysineSaccharomyces cerevisiaefood and beveragesTitratable acidPlant Sciencelcsh:Fermentation industries. Beverages. Alcoholbiology.organism_classificationBiochemistry Genetics and Molecular Biology (miscellaneous)Yeastbread fortificationcommercial baker’s yeastCell densityFermentationFood sciencepistachio powderSettore AGR/16 - Microbiologia AgrariaFood ScienceLeavening agentFermentation
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Chemical composition and antimicrobial activity of the essential oils of some species of Anthemis sect. Anthemis (Asteraceae) from Sicily

2017

The chemical composition of the essential oils isolated from the aerial parts of Anthemis arvensis L. subsp. arvensis, Anthemis cretica subsp. messanensis (Brullo) Giardina & Raimondo and from flowers and leaves of Anthemis cretica subsp. columnae (Ten.) Frezén were determinated by GC–FID and GC–MS analyses. Torreyol (85.4%) was recognised as the main constituent of the Anthemis arvensis subsp. arvensis essential oil, while in the essential oils of Anthemis cretica subsp. messanensis, collected on the rock and cultivated in Hortus Botanicus Panormitanus, (E)-chrysanthenyl acetate (28.8 and 24.2% resp.), 14-hydroxy-α-humulene (8.1 and 5.3% resp.), santolina triene (8 and 5.8% resp.) and …

Drug Evaluation PreclinicalRaimondoAnthemis arvensisFlowersMicrobial Sensitivity TestsPlant Science01 natural sciencesBiochemistryGas Chromatography-Mass Spectrometryessential oillaw.inventionAnalytical Chemistrychemistry.chemical_compoundBridged Bicyclo CompoundsAnti-Infective Agentsantibacterial activitylawSantolinaBotanyOils VolatileAnthemisSettore BIO/15 - Biologia FarmaceuticaChemical compositionSicilyAnthemis arvensis L. subsp. arvensiEssential oiltorreyolBicyclic MonoterpenesPolycyclic Sesquiterpenesalpha-PineneEucalyptolbiology010405 organic chemistryOrganic ChemistryAnthemis cretica subsp. columnae (Ten.) FrezénAsteraceaebiology.organism_classificationCyclohexanols0104 chemical sciencesPlant Leaves010404 medicinal & biomolecular chemistryEucalyptolchemistryMonoterpenesAnthemis cretica subsp. messanensis (Brullo) Giardina &ampAnthemisSesquiterpenes
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From In Silico to Experimental Validation: Tailoring Peptide Substrates for a Serine Protease.

2020

Smart nanocarriers for the transport of drugs to tumor cells are nowadays of great interest for treating cancer. The use of enzymatic stimuli to cleave peptide-based drug nanocapsules for the selective release of nanocapsule cargo in close proximity to tumor cells opens new possibilities in cancer research. In the present work, we demonstrate a methodology for finding and optimizing cleavable substrate sequences by the type II transmembrane serine protease hepsin, which is highly overexpressed in prostate cancer. The design and screening of combinatorial libraries in silico against the binding cavity of hepsin allow the identification of a panel of promising substrates with high-calculated …

DrugMalePolymers and PlasticsIn silicoHepsinmedia_common.quotation_subjectBioengineeringPeptide02 engineering and technology010402 general chemistry01 natural sciencesNanocapsulesBiomaterialsCleaveCell Line TumorMaterials ChemistryHumansComputer Simulationmedia_commonSerine proteasechemistry.chemical_classificationbiologyChemistryProstatic Neoplasms021001 nanoscience & nanotechnology0104 chemical sciencesBiochemistrybiology.proteinNanocarriersSerine Proteases0210 nano-technologyPeptidesBiomacromolecules
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Solar UV-B radiation affects leaf quality and insect herbivory in the southern beech tree Nothofagus antarctica

2004

We examined the effects of solar ultraviolet-B (UV-B) radiation on plant-insect interactions in Tierra del Fuego (55°S), Argentina, an area strongly affected by ozone depletion because of its proximity to Antarctica. Solar UV-B under Nothofagus antarctica branches was manipulated using a polyester plastic film to attenuate UV-B (uvb-) and an Aclar film to provide near-ambient UV-B (uvb+). The plastic films were placed on both north-facing (i.e., high solar radiation in the Southern Hemisphere) and south-facing branches. Insects consumed 40% less leaf area from north- than from south-facing branches, and at least 30% less area from uvb+ branches than from uvb-branches. The reduced herbivory …

EcophysiologyInsectaUltraviolet RaysPlastic filmAntarctic RegionsTreesGALLIC ACIDCiencias Biológicaschemistry.chemical_compoundBotanyAnimalsOZONE DEPLETIONBeechEcosystemEcology Evolution Behavior and SystematicsNothofagusbiologyFLAVONOIDSbiology.organism_classificationOzone depletionFagaceaePlant LeavesAglyconechemistryLarvaSunlightNothofagus antarcticaOtros Tópicos BiológicosHERBIVORYNOTHOFAGUSCIENCIAS NATURALES Y EXACTAS
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Dalle Cronache del mal d’amore al ciclo dell’Amica geniale: continuità ed evoluzione nella narrativa di Elena Ferrante

2019

The paper analyzes the whole narrative production of Elena Ferrante, emphasizing its unity and cohesion. Cohesion coexists with discontinuity: the publication of My Brilliant Friend marks an inventive turning point and reveals new strategies. But it’s even remarkable Ferrante’s predilection for a narrative in which «the flow of storytelling that despite its density manages to sweep you away».

Elena Ferrante Troubling love The days of abandonment The lost daughter Neapolitan novels My Brilliant Friend The Story of a New Name Those Who Leave and Those Who Stay The Story of the Lost Child friendship melodramatic imagination frantumaglia dissolving margins.Settore L-FIL-LET/11 - Letteratura Italiana Contemporanea
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New Alkenylresorcinols with Cytotoxic and Antimicrobial Activities from the Leaves of Embelia schimperi.

2020

AbstractA phytochemical study of the methanol extract of the leaves of Embelia schimperi resulted in the isolation of three new alkenylresorcinols, 1 – 3, together with the known analogs 4 – 7. Their structures were established by a combination of spectroscopic techniques. Compounds 1 – 7 exhibited moderate cytotoxic activity against human cervical cancer cells HeLa-S3 and more pronounced antimicrobial properties towards bacteria and filamentous fungi. The present study falls into an ongoing research project on the characterization of bioactive phenolic lipids from plants of the family Primulaceae.

EmbeliaPhytochemicalsPharmaceutical ScienceEmbelia01 natural sciencesAnalytical ChemistryAnti-Infective AgentsDrug DiscoveryCytotoxic T cellHumansCytotoxicityPharmacologyTraditional medicinebiology010405 organic chemistryChemistryPlant ExtractsOrganic ChemistryIsolation (microbiology)biology.organism_classificationAntimicrobial0104 chemical sciencesPlant Leaves010404 medicinal & biomolecular chemistryPrimulaceaeComplementary and alternative medicinePhytochemicalMolecular MedicineBacteriaPlanta medica
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Job insecurity and sickness absence: Correlations between attrition and absence in 36 occupational groups

2012

Aims: To investigate how job insecurity, as indicated by attrition rates out of employment, affects sickness absence among remaining workers. Methods: A longitudinal analysis investigated how the percentage of workers absent due to sickness was affected by attrition out of employment in Norwegian Labour Force Surveys from 1997 to 2005, between 31 quarterly observations at the level of 36 occupational groups. Results: Rising attrition is associated with more sickness absence. Conclusions: Previous research has argued that job insecurity can lead to more absence because of a stressor effect as well as to less absence because of a disciplinary effect. This research indicates that the stressor…

EmploymentSickness absenceOccupational groupJob stressJob insecurityNorwayLongitudinal databusiness.industryUncertaintyPublic Health Environmental and Occupational HealthGeneral Medicinemedicine.diseaseEnvironmental healthAbsenteeismPersonnel DownsizingAbsenteeismmedicineHumansAttritionLongitudinal StudiesOccupationsSick LeavebusinessStress PsychologicalScandinavian Journal of Public Health
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Work incapacity among family caregivers : a record linkage study

2022

BackgroundFamily caregiving-related physical and mental health problems may lead to work incapacity in employed caregivers. The aim of this study was to quantify sickness absences and disability pensions (SADP) among high-intensity family caregivers available to the labour market compared with a control population.MethodsThe study sample included all individuals in Finland, who had received caregiver’s allowance and were available to the labour market in 2012 (n=16 982) and their controls (n=35 371). Information on the number of sickness absence (spells >10 days) and disability pension (SADP) days and related diagnoses according to ICD-10 were obtained from national registers for the yea…

EmploymentSwedenSTRESSIMPACTEpidemiologyPublic Health Environmental and Occupational Healthsairauspoissaolot3142 Public health care science environmental and occupational healthmielenterveysongelmatPensionsCaregiversomaishoitajatmielenterveyshäiriötoccupational healthINFORMAL CAREGIVERSrecord linkageHumansDisabled PersonsHEALTHGENDERSick LeaveTERM SICKNESS ABSENCEmental healthtyökyvyttömyys
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Rare earths and trace elements contents in leaves: A new indicator of the composition of atmospheric dust

2017

The relationship between the trace element distribution in atmospheric particles and leaves of some exposed plants in the environment was recently demonstrated. This indication would suggest that the trace element analysis of leaves in these plants could provide information about the composition, nature and origin of the atmospheric dust dispersed in the environment. In order to corroborate this hypothesis, the distribution of trace elements and Rare Earths were studied in leaves of some endemic plants, in the atmospheric fallout and in soils of rural, urban and industrial ecosystems in Sicily. These elements have been chosen to discriminate the source and nature of different source on atmo…

Environmental Engineering010504 meteorology & atmospheric sciencesHealth Toxicology and MutagenesisSettore AGR/13 - Chimica Agraria010501 environmental sciencesPlant Roots01 natural sciencesSoilREE La anomaly Leaves anthropogenic signature trace elementsEnvironmental ChemistryEcosystemSoil compositionSicily0105 earth and related environmental sciencesAtmosphereAnomaly (natural sciences)Public Health Environmental and Occupational HealthTrace elementDustGeneral MedicineGeneral ChemistryAtmospheric dustPollutionTrace ElementsSettore GEO/08 - Geochimica E VulcanologiaPlant LeavesTrace (semiology)Environmental chemistrySoil waterEnvironmental scienceMetals Rare EarthComposition (visual arts)Environmental MonitoringChemosphere
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