Search results for "lh"
showing 10 items of 925 documents
Ventricular Fibrillation and Tachycardia Detection Using Features Derived from Topological Data Analysis
2022
A rapid and accurate detection of ventricular arrhythmias is essential to take appropriate therapeutic actions when cardiac arrhythmias occur. Furthermore, the accurate discrimination between arrhythmias is also important, provided that the required shocking therapy would not be the same. In this work, the main novelty is the use of the mathematical method known as Topological Data Analysis (TDA) to generate new types of features which can contribute to the improvement of the detection and classification performance of cardiac arrhythmias such as Ventricular Fibrillation (VF) and Ventricular Tachycardia (VT). The electrocardiographic (ECG) signals used for this evaluation were obtained from…
Endocrine and ovarian response after a 2-day controlled suckling and eCG treatment in lactating rabbit does.
2006
Synchronization methods are used to obtain higher fertility when artificial insemination (AI) is applied to lactating rabbit does. The most common methods are eCG administration or temporary doe–litter separation. Nevertheless, drawbacks have been reported, such as negative side effects of hormonal treatment in the doe and low litter growth due to absence of suckling, respectively. Recently, improved reproductive performance (without visible consequences on young rabbit growth), has been obtained by applying a 2-day controlled nursing method before AI, by allowing for a 10 min nursing of the litter 24 h of separation. The present study was undertaken to examine the pituitary (PRL, LH, FSH) …
Recent European Food Safety Authority toxicological evaluations of major phthalates used in food contact materials
2009
During the 1980s and 1990s, and at the EU level, the Scientific Committee for Food evaluated a number of phthalates that were being used, or were requested for use, as additives in plastics. At this time, peroxisome proliferation was considered as the pivotal effect on which toxicological evaluation of these chemicals was based. At the end of 1990s, a general consensus has been agreed that rodents are highly sensitive to the phenomenon of peroxisome proliferation and that this particular effect should not be used for human risk assessment. Consequently in 2004, it was requested from the newly created European Food Safety Authority to perform a new evaluation of the mainly used phthalates on…
Zvaigžņotā Debess: 2012, Vasara (216)
2012
Contents: “ZVAIGŽŅOTĀ DEBESS” FORTY YEARS AGO: E.Bervalds. From Intention to Reality (abridged) ; A.Egle. Conceptions of Our Ancestry About Heavenly Bodies and Astronomical Phenomena (abridged) ; NEWS: I.Eglītis. Asteroid Discovered at Baldone Observatory Named after Ikaunieks ; A.Alksnis. ALMA Helps to Study Planetary System of Star Fomalhaut ; A.Alksnis. More than Ten Light-Years Long Filament of Cosmic Dust Discovered ; A.Alksnis. Billions of Rocky Planets in the Milky Way ; SPACE RESEARCH and EXPLORATION: M.Sudārs. The Little Secret Space Shuttle Is Flying! ; M.Sudārs. Too Much Litter! Not in Rubbish Dump, but in the Space! ; “ENERĢIJA un PASAULE” VISITS “ZVAIGŽŅOTĀ DEBESS”: Talk with D…
GABA-A receptoru agonista muscimola ietekme uz acetilholīna daudzumu Alcheimera slimības tipa modeļdzīvnieku smadzenēs
2017
Šī darba mērķis bija noskaidrot muscimola ļoti zemu devu (0,01 un 0,05 mg/kg) efektus uz acetilholīna šķelšanu intracerebroventrikulāras (i.c.v.) streptozocīna (STZ) ievadīšanas AD-tipa modelī. Rezultāti rāda, ka: 1.STZ i.c.v. ievadīšana izraisīja būtisku garozas un hipokampa AChE blīvuma palielinājumu. 2.Muscimols 0,01 un 0,05 mg/kg devās normalizēja AChE blīvumu STZ grupas žurku garozā un hipokampā līdz kontroles grupas līmenim. Iegūtie dati ļauj secināt, ka muscimola ļoti mazas devas regulē acetilholīna daudzumu i.c.v. STZ modelī. Iespējams, šis regulācijas mehānisms atbild par iepriekš novērotiem telpiskās atmiņas uzlabojumiem AD-tipa modeļdzīvniekos, tomēr ir nepieciešami tālāki pētīju…
Glutathione metabolism under the influence of hydroperoxides in the lactating mammary gland of the rat. Effect of glucose and extracellular ATP.
1987
Tert-butyl hydroperoxide decreases GSH and total free glutathione (GSH+2GSSG) contents of acini from lactating mammary glands. The decrease in total free glutathione can be explained by an increase in mixed disulfide formation and by excretion of GSS G to the extracellular medium, and subsequent degradation catalyzed by gamma-glutamyl transpeptidase. Low concentrations of glucose prevented the changes in glutathione levels induced by the peroxide. In the presence of extracellular ATP, glucose did not prevent these changes. However, incubations with the peroxide, did not alter the rate of other metabolic pathways by acini.
HISTÓRIA DA LOUCURA E DANAÇÃO DA NORMA: UMA GENEALOGIA DO TRABALHO COMO TECNOLOGIA DE CONTROLE UTILIZADA PELA PSIQUIATRIA CLÁSSICA
2020
Baseados na análise genealógica de Foucault (2014) em História da loucura: na idade clássica, verificamos que a psiquiatria legitima- se como ciência amparada pelo discurso moral da época clássica nos séculos XVII e XVIII. Na obra de Machado et al. (1978) Danação da norma: medicina social e constituição da psiquiatria no Brasil, é apresentado um histórico do surgimento da medicina social e da psiquiatria no Brasil. Foucault (2014) verifica que a época clássica é marcada pela condenação e exclusão da pobreza, por meio do enclausuramento e da prática de trabalhos forçados impostos aos sujeitos considerados improdutivos, pela sociedade. Nesse contexto, a segregação e o uso da força de trabalho…
First experimental study of photon polarization in radiative B0s decays.
2017
The polarization of photons produced in radiative $B^{0}_{s}$ decays is studied for the first time. The data are recorded by the LHCb experiment in $pp$ collisions corresponding to an integrated luminosity of 3fb$^{-1}$ at center-of-mass energies of $7$ and $8$TeV. A time-dependent analysis of the $B^{0}_{s} \to \phi \gamma$ decay rate is conducted to determine the parameter ${\mathcal{A}}^\Delta$, which is related to the ratio of right- over left-handed photon polarization amplitudes in $b \to s \gamma$ transitions. A value of ${\mathcal{A}}^\Delta=-0.98^{\,+0.46\,+0.23}_{\,-0.52\,-0.20}$ is measured. This result is consistent with the Standard Model prediction within two standard deviatio…
Magnetic Monopole Search with the Full MoEDAL Trapping Detector in 13 TeV pp Collisions Interpreted in Photon-Fusion and Drell-Yan Production
2019
MoEDAL is designed to identify new physics in the form of stable or pseudostable highly ionizing particles produced in high-energy Large Hadron Collider (LHC) collisions. Here we update our previous search for magnetic monopoles in Run 2 using the full trapping detector with almost four times more material and almost twice more integrated luminosity. For the first time at the LHC, the data were interpreted in terms of photon-fusion monopole direct production in addition to the Drell-Yan-like mechanism. The MoEDAL trapping detector, consisting of 794 kg of aluminum samples installed in the forward and lateral regions, was exposed to 4.0 fb$^{-1}$ of 13 TeV proton-proton collisions at the LHC…
Redox regulation of genome stability by effects on gene expression, epigenetic pathways and DNA damage/repair
2015
Reactive oxygen and nitrogen species (e.g. H2O2, nitric oxide) confer redox regulation of essential cellular signaling pathways such as cell differentiation, proliferation, migration and apoptosis. In addition, classical regulation of gene expression or activity, including gene transcription to RNA followed by translation to the protein level, by transcription factors (e.g. NF-κB, HIF-1α) and mRNA binding proteins (e.g. GAPDH, HuR) is subject to redox regulation. This review will give an update of recent discoveries in this field, and specifically highlight the impact of reactive oxygen and nitrogen species on DNA repair systems that contribute to genomic stability. Emphasis will be placed …