Search results for "ligand"

showing 10 items of 2559 documents

Equilibrium and structural studies of complexes with a hexadentate ligand containing amide, amine and pyridyl nitrogen donors. Crystal structures of …

2002

A novel potentially hexadentate ligand, 1,8-bis(2-pyridylcarbamoyl)-3,6-diazaoctane (pyctrien) has been synthesised as its tetrahydrochloride salt; its protonation constants and the stability constants of the copper(II) and nickel(II) chelates have been determined by potentiometry. Amide group deprotonation permits the formation of [MLH−1]+ and [MLH−2] species in all cases, whereas the detection of the neutral or the protonated species depends on the nature of the metal ions. The solid complexes of copper, nickel and cobalt with the neutral and the deprotonated ligand have been synthesised and characterised by IR and UV–VIS spectroscopy. The amidic groups are coordinated through the oxygen …

inorganic chemicals010405 organic chemistryLigandInorganic chemistrychemistry.chemical_elementProtonationGeneral Chemistry[CHIM.INOR]Chemical Sciences/Inorganic chemistry010402 general chemistry01 natural sciencesSquare pyramidal molecular geometry0104 chemical scienceschemistry.chemical_compoundNickelCrystallographyDeprotonationchemistryAmidePyridine[CHIM.COOR]Chemical Sciences/Coordination chemistryCobaltComputingMilieux_MISCELLANEOUS
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Structural Origin of Metal Specificity in Isatin Hydrolase from Labrenzia aggregata Investigated by Computer Simulations.

2017

We performed quantum-chemical calculations, ab initio molecular dynamics, hybrid quantum mechanics/molecular mechanics (QM/MM) and enhanced sampling metadynamics simulations to investigate the origin of metal specificity in isatin hydrolase from Labrenzia aggregata. The peculiar octahedral binding geometry of the Mn2+ ion in the Michaelis complex includes both the isatin substrate and the catalytic water within the first coordination shell of the cation. Our calculations show that the same arrangement of the ligands cannot be efficiently achieved in the presence of other small divalent metal cations such as Zn2+ or Cu2+ . On the contrary, bulkier alkaline-earth cations such as Mg2+ , which …

inorganic chemicals0301 basic medicineIsatinCations DivalentHydrolasesMolecular Dynamics SimulationLigands01 natural sciencesCatalysisQM/MMMetal03 medical and health sciencesMolecular dynamicschemistry.chemical_compoundNucleophileBacterial Proteins0103 physical sciencesHydrolaseMoietyComputer SimulationRhodobacteraceae010306 general physicsIsatinOrganic ChemistryMetadynamicsWaterGeneral ChemistryCrystallography030104 developmental biologychemistryMetalsvisual_artvisual_art.visual_art_mediumQuantum TheoryThermodynamicsProtein BindingChemistry (Weinheim an der Bergstrasse, Germany)
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Asymmetric [N–I–N]+halonium complexes in solution?

2020

Assessment of the solution equilibria of [bis(pyridine)iodine(I)]+ complexes by ESI-MS and NMR reveals the preference of iodine(I) to form complexes with a more basic pyridine. Mixtures of symmetric [bis(pyridine)iodine(I)]+ complexes undergo statistical ligand exchange, with a predominant entropic driving force favoring asymmetric systems. The influence of ligand basicity, concentration, temperature, and ligand composition is evaluated. Our findings are expected to facilitate the investigations, and the supramolecular and synthetic applications of halonium ions’ halogen bonds. peerReviewed

inorganic chemicals2019-20 coronavirus outbreakliuoksetLigandMetals and AlloysSupramolecular chemistrychemistry.chemical_elementliganditkompleksiyhdisteetGeneral ChemistryIodineMedicinal chemistryCatalysisSurfaces Coatings and FilmsElectronic Optical and Magnetic MaterialsIonjodichemistry.chemical_compoundchemistryPyridineHalogenMaterials ChemistryCeramics and CompositesHalonium ionChemical Communications
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On the Complexation of Cu(II) and Cd(II) With Polycarboxyl Ligands. Potentiometric Studies With ISE-H+, ISE-Cu2+, and ISE-Cd2+

2009

The interaction of Cu2+ and Cd2+ ions with polyacrylates (PAA, 2 kDa and 100 kDa), polymetacrylate(PMA, 5.4 kDa), and alginate (AA, 70 kDa to 100 kDa) was studied by potentiometry, using ISE-Cu2+, ISE-Cd2+, and ISE-H+ electrodes. The investigations were performed in NaNO3 aqueous solutions, in the ionic strength range 0.10 e I (mol ·L-1) e 0.75, at T ) 298.15 K. The “diprotic-like model” was used to explain the acid-base behavior of the polycarboxylates under investigation (for this model, the monomeric unit of the polyelectrolyte is considered as a dicarboxylate). The results give evidence for the formation of the ML species in all the systems investigated. In addition, the MLH species was…

inorganic chemicalsAcrylate polymerchemistry.chemical_classificationSequestering abilitypolycarboxylic acidsLigandGeneral Chemical EngineeringIonic strength dependencePotentiometric titrationInorganic chemistryGeneral ChemistryUronic acidComplexation Potentiometric study polyelectrolytesPolysaccharidePolyelectrolytechemistry.chemical_compoundchemistryIonic strengthSodium nitrateSettore CHIM/01 - Chimica Analiticapolycarboxylic acids; Sequestering ability; Ionic strength dependenceNuclear chemistryJournal of Chemical & Engineering Data
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Impact of Organoaluminum Compounds on Phenoxyimine Ligands in Coordinative Olefin Polymerization. A Theoretical Study

2013

The reduction of the phenoxyimine moiety in three individual species—namely free ligand, aluminum complex, and titanium complex—with aluminum alkyls and aluminum hydride has been studied by means of DFT. It was demonstrated that the free phenoxyimine ligand in an equimolar mixture with trimethylaluminum does not undergo reduction. Instead, experimentally observed formation of the six-membered cyclic aluminum–phenoxyimine complex, useful in the ring-opening polymerization of lactones, takes place as the kinetically and thermodynamically favored process. However, it is anticipated that a 2-fold excess of the aluminum compound, especially aluminum hydride, acting on the resulting cyclic comple…

inorganic chemicalsAluminum ComplexChemistryLigandOrganic ChemistryALUMINUM HYDRIDEchemistry.chemical_elementcomplex mixturesInorganic ChemistryAluminiumPolymer chemistryMoietyOlefin polymerizationPhysical and Theoretical ChemistryTitaniumOrganometallics
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An Off-On-Off Fluorescent Sensor for pH Windows Based on the 13aneN4-Zn 2+ System

2016

International audience; The new ligand L was prepared and features a 13-membered tetraaza macrocyclic ring with a 1,8-naphthalimide fluorophore appended to a C atom of its backbone. The protonation constants of L as well as its complexation constants with Zn2+ ions were determined in 1:1 water/methanol solutions by potentiometric titrations. Fluorimetric pH titrations were performed with L alone and L in the presence of Zn2+ ions (1:1), and the species distributions (%) versus pH were compared. A window-shaped fluorescence trend was observed with pH for the L/Zn2+ system, which behaves as an off-on-off pH sensor. The on window is centred in the 6.5-7.5 pH range, in correspondence with the f…

inorganic chemicalsFluorophorePotentiometric titrationInorganic chemistryProtonationYeast cellsSensors; Fluorescence; Zinc; Yeast cells; Macrocyclic ligands010402 general chemistry01 natural sciencesMicelleFluorescenceInorganic Chemistrychemistry.chemical_compoundMacrocyclic ligandsCyclamLipophilicity[SDV.IDA]Life Sciences [q-bio]/Food engineeringEquilibriaMicellesIonsChemosensors010405 organic chemistryLigandSensorsChelation-enhanced fluorescencezinc[ SDV.IDA ] Life Sciences [q-bio]/Food engineeringMetal-complexesFluorescence0104 chemical scienceschemistryCyclamTitrationMacrocycles
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The fnr Gene of Bacillus licheniformis and the Cysteine Ligands of the C-Terminal FeS Cluster

1998

Many of the O2-responsive gene regulators of bacteria are members of the fumarate nitrate reductase-cyclic AMP receptor protein family of transcriptional regulators (12, 13, 15, 17) with predicted structures similar to those of the cyclic AMP receptor protein (11). The Fnr (stands for fumarate nitrate reductase regulator) protein from Escherichia coli (FnrEc) controls the expression of a variety of genes, mainly of anaerobic respiration and metabolism (5, 13). It contains a N-terminal cluster of three essential cysteine residues which are supposed to bind together with Cys122 a [4Fe 4S]2+ cluster which is required for O2 sensing (4, 7, 8, 10, 16). A wide variety of gram-negative bacteria co…

inorganic chemicalsIron-Sulfur ProteinsMolecular Sequence DataRestriction MappingMutantBacillusGenetics and Molecular BiologySequence alignmentmacromolecular substancesBacillus subtilisLigandsNitrate reductaseenvironment and public healthMicrobiologyBacterial ProteinsAmino Acid SequenceCysteineBacillus licheniformisMolecular BiologyPeptide sequenceBacillus megateriumSequence Homology Amino AcidbiologyEscherichia coli ProteinsGene Expression Regulation Bacterialbiology.organism_classificationenzymes and coenzymes (carbohydrates)KineticsBiochemistryBacillus megateriumbacteriaSequence AlignmentBacillus subtilisTranscription FactorsCysteineJournal of Bacteriology
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Synthesis, Characterization, and Cu(2+) Coordination Studies of a 3-Hydroxy-4-pyridinone Aza Scorpiand Derivative.

2016

The synthesis, acid-base behavior, and Cu(2+) coordination chemistry of a new ligand (L1) consisting of an azamacrocyclic core appended with a lateral chain containing a 3-hydroxy-2-methyl-4(1H)-pyridinone group have been studied by potentiometry, cyclic voltammetry, and NMR and UV-vis spectroscopy. UV-vis and NMR studies showed that phenolate group was protonated at the highest pH values [log K = 9.72(1)]. Potentiometric studies point out the formation of Cu(2+) complexes of 1:2, 2:2, 4:3, 1:1, and 2:1 Cu(2+)/L1 stoichiometries. UV-vis analysis and electrochemical studies evidence the implication of the pyridinone moieties in the metal coordination of the 1:2 Cu(2+)/L1 complexes. L1 shows …

inorganic chemicalsMagnetic Resonance SpectroscopyStereochemistryPyridinesPyridonesPotentiometric titrationProtonationChemistry Techniques Synthetic010402 general chemistry010403 inorganic & nuclear chemistryElectrochemistryCrystallography X-Ray01 natural sciencesMedicinal chemistryAntioxidantsCoordination complexInorganic Chemistrychemistry.chemical_compoundStructure-Activity RelationshipCoordination ComplexesHumansChelationPhysical and Theoretical ChemistryCell ProliferationChelating Agentschemistry.chemical_classificationLigandHydrogen-Ion Concentration0104 chemical scienceschemistryPotentiometrySpectrophotometry UltravioletCyclic voltammetryDerivative (chemistry)CopperHeLa CellsInorganic chemistry
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Tailoring polymers through interplay of ligands within precatalysts: 8-(Nitro/benzhydryl-arylimino)-7,7-dimethyl-5,6-dihydroquinolylnickel halides in…

2017

A series of 8-(nitro/benzhydryl-substituted arylimino)-7,7-dimethyl-5,6-dihydroquinolines and the corresponding nickel halide complexes were synthesized and characterized. Molecular structures of representative nickel complexes were determined by single crystal X-ray diffraction, showing the dinuclear dimers with distorted square-pyramidal geometry around the nickel center. The binding energies determined by X-ray photoelectron spectroscopy (XPS) indicate the effective coordination between the sp2-nitrogen and nickel atoms as well as the influence of both the halogen ligands and the substituents within dihydroquinolines on the strength of the NiN bond. Ethylene polymerization with the nicke…

inorganic chemicalsPolymers and PlasticsMethylaluminoxaneSubstituentHalidechemistry.chemical_element010402 general chemistry01 natural sciencesvinylene groupnickelchemistry.chemical_compoundBromideVinylene groupPolymer chemistryMaterials ChemistryOrganic chemistrynitro substituent010405 organic chemistryChemistryLigandOrganic Chemistryhomogeneous catalysis0104 chemical sciencesNickelPolymerizationpolymerization
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Bis[S-hexyl 3-(thiophen-2-ylmethylidene)dithiocarbazato-κ2N3,S]palladium(II)

2016

In the title complex, [Pd(C12H17N2S3)2], the PdIIatom exhibits a square-planar coordination geometry with theN,S-chelating ligands arranged in atransconfiguration. Intramolecular C—H...S hydrogen bonds are observed. In the crystal, molecules are linked by weak C—H...N hydrogen-bond interactions, forming chains parallel to thebaxis.

inorganic chemicalsQuantitative Biology::Biomoleculescrystal structureChemistryStereochemistryHydrogen bondThio-chemistry.chemical_elementGeneral MedicineCrystal structure010402 general chemistry010403 inorganic & nuclear chemistry01 natural sciencesMedicinal chemistryhumanitiespalladium(II) complex0104 chemical sciencesCrystalTrans configurationlcsh:QD901-999lcsh:Crystallographydithiocarbazate ligandCoordination geometryPalladiumIUCrData
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