Search results for "ligandit"

showing 10 items of 54 documents

Conformation and dynamics of the ligand shell of a water-soluble Au102 nanoparticle

2016

Inorganic nanoparticles, stabilized by a passivating layer of organic molecules, form a versatile class of nanostructured materials with potential applications in material chemistry, nanoscale physics, nanomedicine and structural biology. While the structure of the nanoparticle core is often known to atomic precision, gaining precise structural and dynamical information on the organic layer poses a major challenge. Here we report a full assignment of 1H and 13C NMR shifts to all ligands of a water-soluble, atomically precise, 102-atom gold nanoparticle stabilized by 44 para-mercaptobenzoic acid ligands in solution, by using a combination of multidimensional NMR methods, density functional t…

Magnetic Resonance SpectroscopyScienceGeneral Physics and AstronomyNanoparticleMetal NanoparticlesNanotechnologypara-mercaptobenzoic acid02 engineering and technologyMolecular Dynamics Simulation010402 general chemistry01 natural sciencesGeneral Biochemistry Genetics and Molecular BiologyArticleMolecular dynamicsta116Multidisciplinaryta114LigandligandsQGeneral ChemistryNuclear magnetic resonance spectroscopyliganditCarbon-13 NMR021001 nanoscience & nanotechnology0104 chemical sciencesStructural biologygold nanoparticlesNanomedicineDensity functional theoryGold0210 nano-technologyNature Communications
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Metallogel formation in aqueous DMSO by perfluoroalkyl decorated terpyridine ligands.

2016

Terpyridine based ligands 1 and 2, decorated with a C8F17 perfluorinated tag, are able to form stable thermoreversible gels in the presence of several d-block metal chloride salts. The gel systems obtained have been characterized by NMR, X-ray diffraction, electron microscopies and Tgel experiments in order to gain insights into the observed different behaviour of the two similar ligands, also in terms of the effect of additional common anionic species. peerReviewed

Metal chlorideAqueous solutiongelation capabilitiesligands02 engineering and technologyligandit010402 general chemistry021001 nanoscience & nanotechnology01 natural sciences0104 chemical sciencesInorganic Chemistrychemistry.chemical_compoundchemistrymetallogel formationPolymer chemistryOrganic chemistryTerpyridine0210 nano-technologyDMSOta116Dalton transactions (Cambridge, England : 2003)
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Bipyridine based metallogels: an unprecedented difference in photochemical and chemical reduction in the in situ nanoparticle formation

2017

Metal co-ordination induced supramolecular gelation of low molecular weight organic ligands is a rapidly expanding area of research due to the potential in creating hierarchically self-assembled multi-stimuli responsive materials. In this context, structurally simple O-methylpyridine derivatives of 4,4′-dihydroxy-2,2′-bipyridine ligands are reported. Upon complexation with Ag(I) ions in aqueous dimethyl sulfoxide (DMSO) solutions the ligands spontaneously form metallosupramolecular gels at concentrations as low as 0.6 w/v%. The metal ions induce the self-assembly of three dimensional (3D) fibrillar networks followed by the spontaneous in situ reduction of the Ag-centers to silver nanopartic…

Metal ions in aqueous solutionta221Supramolecular chemistryNanoparticleContext (language use)02 engineering and technology010402 general chemistryPhotochemistry01 natural sciencesSilver nanoparticleInorganic ChemistryBipyridinechemistry.chemical_compoundmetallogelsta116Aqueous solutionligandsLigandChemistryliganditsupramolecular gelation021001 nanoscience & nanotechnology0104 chemical sciencesChemistrynanoparticlesnanohiukkaset0210 nano-technologyDalton Transactions
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Heptacoordinated Molybdenum(VI) Complexes of Phenylenediamine Bis(phenolate): A Stable Molybdenum Amidophenoxide Radical

2013

The syntheses, crystallographic structures, magnetic properties, and theoretical studies of two heptacoordinated molybdenum complexes with N,N′-bis(3,5-di-tert-butyl-2-hydroxyphenyl)-1,2-phenylenediamine (H4N2O2) are reported. A formally molybdenum(VI) complex [Mo(N2O2)Cl2(dmf)] (1) was synthesized by the reaction between [MoO2Cl2(dmf)2] and H4N2O2, whereas the other molybdenum(VI) complex [Mo(N2O2)(HN2O2)] (2) was formed when [MoO2(acac)2] was used as a molybdenum source. Both complexes represent a rare case of the MoVI ion without any multiply bonded terminal ligands. In addition, molecular structures, magnetic measurements, ESR spectroscopy, and density functional theory calculations ind…

Models MolecularMagnetic measurementsFree Radicalssyylliset liganditInorganic chemistryMolecular Conformationchemistry.chemical_elementPhenylenediaminesCrystallography X-RayMolecular conformationIonInorganic ChemistryPhenolsRare casePolymer chemistryOrganometallic CompoundsamidophenoxidePhysical and Theoretical ChemistrySpectroscopyta116Molybdenumradicalta114X-raynon-innocent ligandschemistryMolybdenumradikaalitQuantum TheoryDensity functional theoryamidofenoksidimolybdeeni
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Suitability ofMMGBSAfor the selection of correct ligand binding modes from docking results

2018

The estimation of the correct binding mode and affinity of a ligand into a target protein using computational methods is challenging. However, docking can introduce poses from which the correct binding mode could be identified using other methods. Here, we analyzed the reliability of binding energy estimation using the molecular mechanics-generalized Born surface area (MMGBSA) method without and with energy minimization to identify the likely ligand binding modes within docking results. MMGBSA workflow (a) outperformed docking in recognizing the correct binding modes of androgen receptor ligands and (b) improved the correlation coefficient of computational and experimental results of rescor…

Molecular modelBinding energyta3111LigandsEnergy minimization01 natural sciencesBiochemistrylääkesuunnitteluSubstrate SpecificityCytochrome P-450 CYP2A6Free energy perturbationCoumarinsDrug DiscoveryHumansta317PharmacologyBinding Sitesmolecular modeling010405 organic chemistryChemistryDrug discoveryOrganic Chemistryta1182liganditreceptor and ligandslaskennallinen kemiaLigand (biochemistry)Protein Structure Tertiary0104 chemical sciencesMolecular Docking Simulation010404 medicinal & biomolecular chemistryDocking (molecular)structure based drug-designThermodynamicsMolecular MedicineproteiinitTarget proteinBiological systemProtein BindingChemical Biology & Drug Design
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Series of Near-IR-Absorbing Transition Metal Complexes with Redox Active Ligands

2020

New soluble and intensely near-IR-absorbing transition metal (Ti, Zr, V, Ni) complexes were synthesized using a redox non-innocent N,N&rsquo

Spectrometry Mass Electrospray IonizationMagnetic Resonance SpectroscopyElectronsChemistry Techniques SyntheticCrystallography X-RayLigandsArticlelcsh:QD241-441Magneticslcsh:Organic chemistryX-Ray DiffractionCoordination ComplexesNickelTransition Elementsorgaaniset yhdisteetSpectroscopy Near-InfraredMolecular Structureredox-active ligandnon-innocent ligandsElectrochemical Techniquesliganditkompleksiyhdisteetmetal organic complexMetalsElectronicsOxidation-Reduction
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Synthesis of a labile sulfur-centred ligand, [S(H)C(PPh2S)2]−: structural diversity in lithium(i), zinc(ii) and nickel(ii) complexes

2016

A high-yield synthesis of [Li{S(H)C(PPh2S)2}]2 [Li2·(3)2] was developed and this reagent was used in metathesis with ZnCl2 and NiCl2 to produce homoleptic complexes 4 and 5b in 85 and 93% yields, respectively. The solid-state structure of the octahedral complex [Zn{S(H)C(PPh2S)2}2] (4) reveals notable inequivalence between the Zn-S(C) and Zn-S(P) contacts (2.274(1) Å vs. 2.842(1) and 2.884(1) Å, respectively). Two structural isomers of the homoleptic complex [Ni{S(H)C(PPh2S)2}2] were isolated after prolonged crystallization processes. The octahedral green Ni(ii) isomer 5a exhibits the two monoprotonated ligands bonded in a tridentate (S,S',S'') mode to the Ni(ii) centre with three distinctl…

Stereochemistrychemistry.chemical_elementmetal complexes010402 general chemistry01 natural sciencesisomerizationelectronic structuresInorganic Chemistrychemistry.chemical_compoundelektronirakenteetrikkipohjaiset liganditStructural isomerSinglet stateTriplet stateHomolepticta116010405 organic chemistryLigandsulphur-centered ligands0104 chemical sciencesBond lengthNickelCrystallographyOctahedronchemistryisomerisaatiometallikompleksitDalton Transactions
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“Two-Story” Calix[6]arene-Based Zinc and Copper Complexes: Structure, Properties, and O 2 Binding

2017

International audience; A new “two-story” calix[6]arene-based ligand was synthesized, and its coordination chemistry was explored. It presents a tren cap connected to the calixarene small rim through three amido spacers. X-ray diffraction studies of its metal complexes revealed a six-coordinate ZnII complex with all of the carbonyl groups of the amido arms bound and a five-coordinate CuII complex with only one amido arm bound. These dicationic complexes were poorly responsive toward exogenous neutral donors, but the amido arms were readily displaced by small anions or deprotonated with a base to give the corresponding monocationic complexes. Cyclic voltammetry in various solvents showed a r…

[CHIM.INOR] Chemical Sciences/Inorganic chemistryStereochemistry“two-story” calix[6]arene-based ligand[CHIM.INOR]Chemical Sciences/Inorganic chemistry010402 general chemistry01 natural sciencesRedoxCoordination complexInorganic ChemistryMetalDeprotonationCalixarenePolymer chemistry[CHIM.COOR]Chemical Sciences/Coordination chemistryPhysical and Theoretical ChemistryAnion bindingta116chemistry.chemical_classificationligands010405 organic chemistryChemistryLigandligandit[CHIM.COOR] Chemical Sciences/Coordination chemistry0104 chemical sciencesvisual_artvisual_art.visual_art_mediumCyclic voltammetry
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NHC-Stabilized Au10 Nanoclusters and Their Conversion to Au25 Nanoclusters

2022

Herein, we describe the synthesis of a toroidal Au10 cluster stabilized by N-heterocyclic carbene and halide ligands via reduction of the corresponding NHC−Au−X complexes (X = Cl, Br, I). The significant effect of the halide ligands on the formation, stability, and further conversions of these clusters is presented. While solutions of the chloride derivatives of Au10 show no change even upon heating, the bromide derivative readily undergoes conversion to form a biicosahedral Au25 cluster at room temperature. For the iodide derivative, the formation of a significant amount of Au25 was observed even upon the reduction of NHC−Au−I. The isolated bromide derivative of the Au25 cluster displays a…

absorptiometal clustersanionitligandsnanohiukkasetliganditgoldanionsabsorptionkulta
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Dynamics of the ligand-binding domains of ionotropic glutamate receptors

2010

antagonistsglutamaatitreseptoritligand-binding coresliganditionotrooppiset glutamaattireseptoritligandinsitomistaskutmolecular dynamicsionotropic glutamate receptorshermosolutMD-simulaatiotligand-binding pocketsagonistsvälittäjäaineet
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