Search results for "lino"

showing 10 items of 1310 documents

Loss of endocytic clathrin-coated pits upon acute depletion of phosphatidylinositol 4,5-bisphosphate.

2007

Phosphatidylinositol 4,5-bisphosphate [PI(4,5) P 2 ], a phosphoinositide concentrated predominantly in the plasma membrane, binds endocytic clathrin adaptors, many of their accessory factors, and a variety of actin-regulatory proteins. Here we have used fluorescent fusion proteins and total internal reflection fluorescence microscopy to investigate the effect of acute PI(4,5) P 2 breakdown on the dynamics of endocytic clathrin-coated pit components and of the actin regulatory complex, Arp2/3. PI(4,5) P 2 breakdown was achieved by the inducible recruitment to the plasma membrane of an inositol 5-phosphatase module through the rapamycin/FRB/FKBP system or by treatment with ionomycin. PI(4,5)…

DynaminsPhosphatidylinositol 45-DiphosphateEpsinEndocytic cyclemacromolecular substancesEndocytosisClathrinClathrin coatModels Biologicalchemistry.chemical_compoundChlorocebus aethiopsAnimalsHumansDynaminSirolimusMultidisciplinarybiologyCell MembraneClathrin-Coated VesiclesBiological SciencesActinsEndocytosisCell biologyAdaptor Proteins Vesicular TransportPhosphatidylinositol 45-bisphosphatechemistryActin-Related Protein 3Actin-Related Protein 2COS Cellsbiology.proteinLamellipodiumProceedings of the National Academy of Sciences of the United States of America
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Effects of modulation of body fat in production of adiponectin in mice : consequences on hepatic metabolism of lipids

2010

Adiponectin (ApN), a 30-kDa adipokine abundantly produced by adipose tissue has been described for the first time in 1995. Early findings demonstrating serum adiponectin levels are inversely correlated with obesity initiated intense investigation of the relationship between adiponectin and all symptoms of the metabolic syndrome. Of these studies, strong evidence suggests that a weight loss induced by medication or hypocaloric diet led to increased circulating ApN levels and improvement of biochemical parameters. Thus, high levels of ApN have been correlated with an improvement of insulin sensitivity and lipid parameters reducing cardiovascular risk. However mechanisms involved in the improv…

E-oxydation[SDV.SA] Life Sciences [q-bio]/Agricultural sciences[SDV.MHEP] Life Sciences [q-bio]/Human health and pathologyTissu adipeuxStreptozotocineNo english keywordsGlitazoneAdiponectineObésitéFoieExplantAcide linoléique conjuguéMétabolisme des lipides
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"Variable bin $m_{Z\ell}$ for SR4$\ell$ " of "Search for trilepton resonances from chargino and neutralino pair production in $\sqrt{s}$ = 13 TeV $pp…

2021

The observed data and post-fit SM background expectation as a function of $m_{Z\ell}$ in SR4$\ell$. The $m_{Z\ell}$ binning is the same as used in the fit and the yield is normalized to the bin width, with the last bin normalized using a width of 200 GeV. the "Other" category mostly consists of $tWZ$, $t\bar{t}W$, and $tZ$ processes. The hatched bands indicate the combined theoretical, experimental, and MC statistical uncertainties. The bottom panel shows the significance of the differences between the observed data and expected yields, computed following the profile likelihood method described in ref.[arxiv: physics/0702156]

ElectroweakDN/D$m_{Z\ell}$Proton-Proton ScatteringP P --> CHARGINO- CHARGINO+ XP P --> CHARGINO+ NEUTRALINO1 XSUSYSupersymmetryP P --> CHARGINO+ CHARGINO- X13000P P --> CHARGINO- NEUTRALINO1 X
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"Variable bin $m_{Z\ell}$ for SR3$\ell$ " of "Search for trilepton resonances from chargino and neutralino pair production in $\sqrt{s}$ = 13 TeV $pp…

2021

The observed data and post-fit SM background expectation as a function of $m_{Z\ell}$ in SR3$\ell$. The $m_{Z\ell}$ binning is the same as used in the fit and the yield is normalized to the bin width, with the last bin normalized using a width of 200 GeV. the "Other" category mostly consists of $tWZ$, $t\bar{t}W$, and $tZ$ processes. The hatched bands indicate the combined theoretical, experimental, and MC statistical uncertainties. The bottom panel shows the significance of the differences between the observed data and expected yields, computed following the profile likelihood method described in ref.[arxiv: physics/0702156]

ElectroweakDN/D$m_{Z\ell}$Proton-Proton ScatteringP P --> CHARGINO- CHARGINO+ XP P --> CHARGINO+ NEUTRALINO1 XSUSYSupersymmetryP P --> CHARGINO+ CHARGINO- X13000P P --> CHARGINO- NEUTRALINO1 X
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"Variable bin $m_{Z\ell}$ for SRFR " of "Search for trilepton resonances from chargino and neutralino pair production in $\sqrt{s}$ = 13 TeV $pp$ col…

2021

The observed data and post-fit SM background expectation as a function of $m_{Z\ell}$ in SRFR. The $m_{Z\ell}$ binning is the same as used in the fit and the yield is normalized to the bin width, with the last bin normalized using a width of 200 GeV. the "Other" category mostly consists of $tWZ$, $t\bar{t}W$, and $tZ$ processes. The hatched bands indicate the combined theoretical, experimental, and MC statistical uncertainties. The bottom panel shows the significance of the differences between the observed data and expected yields, computed following the profile likelihood method described in ref.[arxiv: physics/0702156]

ElectroweakDN/D$m_{Z\ell}$Proton-Proton ScatteringP P --> CHARGINO- CHARGINO+ XP P --> CHARGINO+ NEUTRALINO1 XSUSYSupersymmetryP P --> CHARGINO+ CHARGINO- X13000P P --> CHARGINO- NEUTRALINO1 X
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"$\ell=\tau$, Exp_0 " of "Search for trilepton resonances from chargino and neutralino pair production in $\sqrt{s}$ = 13 TeV $pp$ collisions with th…

2021

Exclusion curves for the simplified model of $\tilde\chi^{\pm}_{1}\tilde\chi^{\mp}_{1} + \tilde\chi^{0}_{1}\tilde\chi^{0}_{1}$ pair-production as a function of $\tilde\chi^{\pm}_{1}/\tilde\chi^{0}_{1}$ mass and branching fraction to $Z$ bosons. curves are derived separately when requiring that the charged-lepton decays of the $\tilde\chi^{\pm}_{1}/\tilde\chi^{0}_{1}$ are to a $\tau$-leptons only. the expected 95% CL exclusion (dashed black line) is shown with $\pm1~\sigma_{\mathrm{exp}}$ (yellow band) from systematic and statistical uncertainties on the expected yields. the observed 95% CL exclusion (solid red line) is shown with the $\pm1~\sigma_{\mathrm{theory}}^{\mathrm{susy}}$ (dotted r…

ElectroweakProton-Proton ScatteringCLSP P --> CHARGINO- CHARGINO+ XHigh Energy Physics::PhenomenologyP P --> CHARGINO+ NEUTRALINO1 XSUSYHigh Energy Physics::ExperimentSupersymmetryP P --> CHARGINO+ CHARGINO- X13000P P --> CHARGINO- NEUTRALINO1 X
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"$\ell=(e, \mu, \tau)$, Exp_0_Down " of "Search for trilepton resonances from chargino and neutralino pair production in $\sqrt{s}$ = 13 TeV $pp$ col…

2021

Exclusion curves for the simplified model of $\tilde\chi^{\pm}_{1}\tilde\chi^{\mp}_{1} + \tilde\chi^{0}_{1}\tilde\chi^{0}_{1}$ pair-production as a function of $\tilde\chi^{\pm}_{1}/\tilde\chi^{0}_{1}$ mass and branching fraction to $Z$ bosons. curves are derived separately when requiring that the charged-lepton decays of the $\tilde\chi^{\pm}_{1}/\tilde\chi^{0}_{1}$ are to any lepton with equal probability. the expected 95% CL exclusion (dashed black line) is shown with $\pm1~\sigma_{\mathrm{exp}}$ (yellow band) from systematic and statistical uncertainties on the expected yields. the observed 95% CL exclusion (solid red line) is shown with the $\pm1~\sigma_{\mathrm{theory}}^{\mathrm{susy}…

ElectroweakProton-Proton ScatteringCLSP P --> CHARGINO- CHARGINO+ XHigh Energy Physics::PhenomenologyP P --> CHARGINO+ NEUTRALINO1 XSUSYHigh Energy Physics::ExperimentSupersymmetryP P --> CHARGINO+ CHARGINO- X13000P P --> CHARGINO- NEUTRALINO1 X
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"$\ell=\tau$, Obs_0_Up " of "Search for trilepton resonances from chargino and neutralino pair production in $\sqrt{s}$ = 13 TeV $pp$ collisions with…

2021

Exclusion curves for the simplified model of $\tilde\chi^{\pm}_{1}\tilde\chi^{\mp}_{1} + \tilde\chi^{0}_{1}\tilde\chi^{0}_{1}$ pair-production as a function of $\tilde\chi^{\pm}_{1}/\tilde\chi^{0}_{1}$ mass and branching fraction to $Z$ bosons. curves are derived separately when requiring that the charged-lepton decays of the $\tilde\chi^{\pm}_{1}/\tilde\chi^{0}_{1}$ are to a $\tau$-leptons only. the expected 95% CL exclusion (dashed black line) is shown with $\pm1~\sigma_{\mathrm{exp}}$ (yellow band) from systematic and statistical uncertainties on the expected yields. the observed 95% CL exclusion (solid red line) is shown with the $\pm1~\sigma_{\mathrm{theory}}^{\mathrm{susy}}$ (dotted r…

ElectroweakProton-Proton ScatteringCLSP P --> CHARGINO- CHARGINO+ XHigh Energy Physics::PhenomenologyP P --> CHARGINO+ NEUTRALINO1 XSUSYHigh Energy Physics::ExperimentSupersymmetryP P --> CHARGINO+ CHARGINO- X13000P P --> CHARGINO- NEUTRALINO1 X
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"$\ell=\tau$, Obs_0_Down " of "Search for trilepton resonances from chargino and neutralino pair production in $\sqrt{s}$ = 13 TeV $pp$ collisions wi…

2021

Exclusion curves for the simplified model of $\tilde\chi^{\pm}_{1}\tilde\chi^{\mp}_{1} + \tilde\chi^{0}_{1}\tilde\chi^{0}_{1}$ pair-production as a function of $\tilde\chi^{\pm}_{1}/\tilde\chi^{0}_{1}$ mass and branching fraction to $Z$ bosons. curves are derived separately when requiring that the charged-lepton decays of the $\tilde\chi^{\pm}_{1}/\tilde\chi^{0}_{1}$ are to a $\tau$-leptons only. the expected 95% CL exclusion (dashed black line) is shown with $\pm1~\sigma_{\mathrm{exp}}$ (yellow band) from systematic and statistical uncertainties on the expected yields. the observed 95% CL exclusion (solid red line) is shown with the $\pm1~\sigma_{\mathrm{theory}}^{\mathrm{susy}}$ (dotted r…

ElectroweakProton-Proton ScatteringCLSP P --> CHARGINO- CHARGINO+ XHigh Energy Physics::PhenomenologyP P --> CHARGINO+ NEUTRALINO1 XSUSYHigh Energy Physics::ExperimentSupersymmetryP P --> CHARGINO+ CHARGINO- X13000P P --> CHARGINO- NEUTRALINO1 X
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"$\ell=\tau$, Exp_0_Up " of "Search for trilepton resonances from chargino and neutralino pair production in $\sqrt{s}$ = 13 TeV $pp$ collisions with…

2021

Exclusion curves for the simplified model of $\tilde\chi^{\pm}_{1}\tilde\chi^{\mp}_{1} + \tilde\chi^{0}_{1}\tilde\chi^{0}_{1}$ pair-production as a function of $\tilde\chi^{\pm}_{1}/\tilde\chi^{0}_{1}$ mass and branching fraction to $Z$ bosons. curves are derived separately when requiring that the charged-lepton decays of the $\tilde\chi^{\pm}_{1}/\tilde\chi^{0}_{1}$ are to a $\tau$-leptons only. the expected 95% CL exclusion (dashed black line) is shown with $\pm1~\sigma_{\mathrm{exp}}$ (yellow band) from systematic and statistical uncertainties on the expected yields. the observed 95% CL exclusion (solid red line) is shown with the $\pm1~\sigma_{\mathrm{theory}}^{\mathrm{susy}}$ (dotted r…

ElectroweakProton-Proton ScatteringCLSP P --> CHARGINO- CHARGINO+ XHigh Energy Physics::PhenomenologyP P --> CHARGINO+ NEUTRALINO1 XSUSYHigh Energy Physics::ExperimentSupersymmetryP P --> CHARGINO+ CHARGINO- X13000P P --> CHARGINO- NEUTRALINO1 X
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