Search results for "loop"
showing 10 items of 608 documents
FROM MODELING TO IMPLEMENTING THE PERCEPTION LOOP IN SELF-CONSCIOUS SYSTEMS
2010
Engineering self-conscious robotic systems is a challenging issue because of the intrinsic complexity of such systems; a self-conscious robot has to acquire knowledge, to understand its world and to autonomously interact with its environment. In this paper, the externalist point of view is used for developing a complete process for the design and implementation of a conscious robotic system that is able to interact with a dynamic environment in a human-like fashion without possessing detailed knowledge about the environment and pre-programmed tasks and algorithms. The paper mainly focuses on the configuration part of the whole process that make the robot able to decide and to learn from exp…
Studies in thermal and dynamical duality
2011
Significance of Autologous Interleukin-6 Production in the HA22T/VGH Cell Model of Hepatocellular Carcinoma
2006
Cancer cells may often support their own growth, survival, and drug resistance by autocrine/paracrine loops based on the production of different factors; results from us and others have shown that similar interleukin-6 (IL-6)-related loops are operative in multiple myeloma and prostate or renal cancer. Because this aspect has not been investigated in detail for hepatocellular carcinoma (HCC), we have examined it in HA22T/VGH cells. These differ from other primary liver cancer cell lines (that is, HepG2, HuH-6, and HuH-7) in that enzyme-linked immunosorbent assay (ELISA) showed the HA22T/VGH cells to secrete remarkable amounts of IL-6 (16.8 ng/10(6) cells/24 h); this production, due to const…
Why do Traditional Performance Management Systems in Healthcare not always lead to Improved Performance? Outlining the Unintended Consequences of the…
2021
Researchers all around the globe have not yet come to an end as regards the supposed positive impact of traditional performance management systems in healthcare, and some research has shown that, paradoxically, performance management policies do not always lead to improved hospital performance. Despite the extensive research identifying the “pitfalls” of the NPM reforms around Europe and the unintended consequences for hospital staff and patients, little is known about the mechanisms that caused those negative effects, which essentially creates a research gap worth investigating. This PhD study tries to address this gap and show why do traditional PM Systems in healthcare not always lead to…
Crushing of interstellar gas clouds in supernova remnants. I. The role of thermal conduction and radiative losses
2005
We model the hydrodynamic interaction of a shock wave of an evolved supernova remnant with a small interstellar gas cloud like the ones observed in the Cygnus loop and in the Vela SNR. We investigate the interplay between radiative cooling and thermal conduction during cloud evolution and their effect on the mass and energy exchange between the cloud and the surrounding medium. Through the study of two cases characterized by different Mach numbers of the primary shock (M = 30 and 50, corresponding to a post-shock temperature $T\approx 1.7\times 10^6$ K and $\approx 4.7\times 10^6$ K, respectively), we explore two very different physical regimes: for M = 30, the radiative losses dominate the…
Jejunoileal bypass as the main procedure in the onset of immune-related conditions: the model of BADAS
2013
Bariatric surgery represents a common approach for the control of severe morbid obesity, reducing caloric intake by modifying the anatomy of the gastrointestinal tract. Following jejunoileal bypass, a large spectrum of complications has been described, with rheumatic manifestation present in up to 20% of cases. Although bowel bypass syndrome, also called blind loop syndrome, is a well-recognized complication of jejunoileal bypass, the same syndrome was recognized in patients who had not had intestinal bypass surgery, and the term the 'bowel-associated dermatosis-arthritis syndrome' (BADAS) was coined. The pathogenesis of BADAS is as yet poorly understood and only few data concerning this is…
Design and Validation of a FPGA-Based HIL Simulator for Minimum Losses Control of a PMSM
2021
This work examines the FPGA programmable logic platforms applied to minimum losses control of a Permanent Magnet Synchronous Motor (PMSM), which represents a flexible solution for the implementation of an advanced digital control algorithm, given their intrinsic parallel structure and the capability to be directly reprogrammable in the field. In particular, design and validation of a FPGA-based Hardware-In-the-Loop (HIL) simulator is proposed, by investigating about data format, quantization and discretization effects and other issues arising during the experimental validation of a controller prototype, in order to reduce the embedded software development cycle and test control systems. The…
Numerical Simulations of a Flux Rope Ejection
2015
Coronal mass ejections (CMEs) are the most violent phenomena observed on the Sun. One of the most successful models to explain CMEs is the flux rope ejection model, where a magnetic flux rope is expelled from the solar corona after a long phase along which the flux rope stays in equilibrium while magnetic energy is being accumulated. However, still many questions are outstanding on the detailed mechanism of the ejection and observations continuously provide new data to interpret and put in the context. Currently, extreme ultraviolet (EUV) images from the Atmospheric Imaging Assembly (AIA) on board the Solar Dynamic Observatory (SDO) are providing new insights into the early phase of CME evo…
Small RNA‐binding protein RapZ mediates cell envelope precursor sensing and signaling in Escherichia coli
2019
Abstract The RNA‐binding protein RapZ cooperates with small RNAs (sRNAs) GlmY and GlmZ to regulate the glmS mRNA in Escherichia coli. Enzyme GlmS synthesizes glucosamine‐6‐phosphate (GlcN6P), initiating cell envelope biosynthesis. GlmZ activates glmS expression by base‐pairing. When GlcN6P is ample, GlmZ is bound by RapZ and degraded through ribonuclease recruitment. Upon GlcN6P depletion, the decoy sRNA GlmY accumulates through a previously unknown mechanism and sequesters RapZ, suppressing GlmZ decay. This circuit ensures GlcN6P homeostasis and thereby envelope integrity. In this work, we identify RapZ as GlcN6P receptor. GlcN6P‐free RapZ stimulates phosphorylation of the two‐component sy…
A Robot Architecture Based on Higher Order Perception Loop
2009
The paper discusses the self-consciousness of a robot as based on higher order perceptions of the robot itself. In this sense, the first order perceptions of the robot are the immediate perceptions of the outer world of the robot, while higher order perceptions are the robot perceptions of its own inner world. The resulting architecture based on higher order perceptions has been implemented and tested in a project regarding a robotic touristic guide acting in the Botanical Garden of the University of Palermo.