Search results for "maintenance"

showing 10 items of 392 documents

Good moments in parents' spousal relationships: A daily relational maintenance perspective

2010

This study examined positively experienced spousal moments among couples with young children. The diary data were gathered from 95 women and 55 men in 95 Finnish families over a seven-day period using an open-ended question. Seven kinds of activities were identified in the descriptions of moments: doings, conversations, presence, positivity, physical intimacy, support, and conflict management. Doings related to shared tasks and favors as well as conversations concerning catching up and family issues were more often mentioned by women than by men. Notably, positive spousal moments also often included children who were described as a landscape for the spousal relationship, as participants in …

Sociology and Political ScienceSocial PsychologySpousal relationshipsPerspective (graphical)Context (language use)Relationship maintenanceFamily lifeDevelopmental psychologyPhysical intimacyAnthropologyConflict managementPsychologySocial psychologyPeriod (music)Family Science
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Defining the Process for Making Software System Modernization Decisions

2006

This paper outlines a process for software system modernization decisions. The rationale of the process is explained and the process is defined in a way that allows its adaptation for other organizations and situations. The process is a light-weight one and is based on the use of objective data. The procedures for collecting the data are explained. The process has been used to solve a real industrial decision making situation in which the process was successful.

Software Engineering Process GroupProcess managementComputer scienceProcess (engineering)business.industryBusiness processSoftware developmentSystems engineeringSoftware maintenanceSoftware systemAdaptation (computer science)businessModernization theory
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Solunto: dalla conoscenza alla conservazione

2016

Per l’antica città di Solunto (Santa Flavia-Palermo), solo alla fine del XVIII sec., inizia un processo di analisi finalizzato alla sua conservazione, mediante tutela e restauro, che prosegue fino ai nostri giorni. Pertanto il mio saggio vuole essere un contributo per conoscere e meglio conservare questo patrimonio rappresentato da materiali e strutture, attraverso continue cure, al fine di assicurare vita alla vita delle testimonianze, per la nostra generazione, ma soprattutto per quelle che ci seguiranno. To the ancient city of Solunto (Santa Flavia-Palermo), only in the late Eighteenth century, begins a process of analysis aimed at its preservation, through protection and restoration, wh…

Solunto (Palermo) manutenzione restauro conservazione fruizione e valorizzazione dei siti archeologiciSettore ICAR/19 - RestauroSolunto (Palermo) maintenance restoration conservation use and enhancement of archaeological sites
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Molecular mechanisms of sorafenib action in liver cancer cells.

2012

Sorafenib, a multikinase inhibitor, recently received FDA approval for the treatment of advanced hepatocellular carcinoma (HCC). However, as the clinical application of sorafenib evolves, there is increasing interest in defining the mechanisms underlying its anti-tumor activity. Considering that this specific inhibitor could target unexpected molecules depending on the biologic context, a precise understanding of its mechanism of action could be critical to maximize its treatment efficacy, while minimizing adverse effects. Two human HCC cell lines (HepG2 and Huh7), carrying different biological and genetic characteristics, were used in this study to examine the intracellular events leading …

SorafenibDNA ReplicationNiacinamideCarcinoma HepatocellularDNA RepairTranscription GeneticAngiogenesisCell SurvivalPyridinesApoptosisPharmacologyBiologysorafenib HCC mini-chromosome maintenance genes Dickkopf1 Harakiri Acheron/LARP6 YAP1 cell cycle microarray global gene expression analysisCell Line TumormedicineCell AdhesionHumansneoplasmsMolecular BiologyProtein Kinase InhibitorsCell ProliferationYAP1Neovascularization PathologicCell growthGene Expression ProfilingPhenylurea CompoundsBenzenesulfonatesCell CycleLiver NeoplasmsBiological TransportCell BiologyCell cycleSorafenibmedicine.diseasedigestive system diseasesMechanism of actionHepatocellular carcinomaProtein Biosynthesismedicine.symptomMitogen-Activated Protein KinasesLiver cancerDevelopmental Biologymedicine.drugSignal Transduction
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Sorafenib In Combination with Standard Induction and Consolidation Therapy In Elderly AML Patients: Results From a Randomized, Placebo-Controlled Pha…

2010

Abstract Abstract 333 Background: Standard chemotherapy for elderly AML patients results in a median overall survival of only about one year. Case reports and early phase I/II data have shown that the kinase inhibitor Sorafenib might show clinical benefit for Flt3-ITD-positive AML patients (Metzelder S Blood 2009; 113:6567) and that its addition to standard chemotherapy is feasible (Ravandi F JCO 2010; 28:1856). Sorafenib is a potent Raf, c-Kit and FLT3 inhibitor that may also affect AML blasts and bone marrow (BM) stroma cells via VEGFR and PDGFR-β inhibition. Therefore, we performed a multicenter, randomized, placebo-controlled, double-blind phase II trial in elderly (>60 y) AML pa…

SorafenibOncologymedicine.medical_specialtybusiness.industryImmunologyPhases of clinical researchInduction chemotherapyCell BiologyHematologyNeutropeniamedicine.diseaseBiochemistryChemotherapy regimenSurgeryRegimenMaintenance therapyInternal medicinemedicinebusinessFebrile neutropeniamedicine.drugBlood
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How sustainability factors influence maintenance of water distribution systems feeding manufacturing industries

2022

This work aims to analyse the role played by relevant sustainability factors towards the implementation of maintenance interventions in the manufacturing industrial sector. In this context, we focus on industrial water distribution systems, on whose effective work depends the functioning of core plants as well as general industrial facilities. In detail, we propose aMulti-Criteria Decision-Making (MCDM) application based on the use of the Analytic Network Process (ANP) as amethodological way to prioritise maintenance interventions while considering the influence of some of themost relevant sustainability factors identified in literature. The main advantage of such an approach consists in th…

Sustainability FactorIdustrial SystemsMulit-Criteria Decision-MakingMaintenanceManagementANP
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Evaluating Fleet and Maintenance Management Strategies through System Dynamics Model in a City Bus Company

System DynamicMaintenance Management StrategiesEvaluating Fleet
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Methods of Condition Monitoring and Fault Detection for Electrical Machines

2021

Nowadays, electrical machines and drive systems are playing an essential role in different applications. Eventually, various failures occur in long-term continuous operation. Due to the increased influence of such devices on industry, industrial branches, as well as ordinary human life, condition monitoring and timely fault diagnostics have gained a reasonable importance. In this review article, there are studied different diagnostic techniques that can be used for algorithms’ training and realization of predictive maintenance. Benefits and drawbacks of intelligent diagnostic techniques are highlighted. The most widespread faults of electrical machines are discussed as well as techniques fo…

TechnologyControl and OptimizationComputer scienceHuman lifeReliability (computer networking)condition monitoringfailure detectionEnergy Engineering and Power TechnologyFault (power engineering)Fuzzy logicPredictive maintenanceFault detection and isolationVDP::Teknologi: 500::Elektrotekniske fag: 540Electrical and Electronic EngineeringEngineering (miscellaneous)Artificial neural networkRenewable Energy Sustainability and the EnvironmentTCondition monitoringfault diagnosisartificial intelligenceReliability engineeringVDP::Teknologi: 500machine learningfuzzy logicEnergy (miscellaneous)Energies
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La scoperta, sistemazione e conservazione della grande Iscrizione di Gortina, nell'isola di Creta (1884-1921): la protezione delle testimonianze e le…

2013

La scoperta e la conservazione della Grande Iscrizione di Gortina a Creta, da parte degli studiosi italiani, fra la fine del XIX sec. e i primi decenni del XX sec., rappresentò un grande riconoscimento scientifico-culturale per la giovane nazione italiana. Nel passato, l’isola di Creta era stata legata alla Repubblica di Venezia e anche questo rapporto favorì l’invio a Creta del giovane epigrafista F. Halbherr, il quale fra notevoli peripezie rinvenne, assieme all’epigrafista tedesco E. Fabricius, la famosa l’iscrizione nell’antica città di Gortina. L’iscrizione, fra le più antiche e complete finora conosciute in tutta Europa, conteneva le norme sulla famiglia, l’eredità e in generale i dir…

The discovery and preservation of the Great Inscription of Gortyna in Crete by Italian researchers in the late nineteenth century. and the first decades of the twentieth century. was an important cultural and scientific recognition for the young Italian nation. In the past the island of Crete had been tied to the Republic of Venice and this report also favored sending in Crete the young epigraphist F. Halbherr who among considerable vicissitudes came to together to the epigraphist german E. Fabricius the inclusion of the famous ancient city of Gortyna. The inscription among the oldest and most comprehensive so far known throughout Europe the rules contained on the family's legacy in general and the rights and duties of some of the people of the Minoan civilization (480-450 BC). The inscription was carved on blocks organic limestone a restored ancient building which later in Roman times was turned into odeon. The Laws of Gortyn were engraved on the remains of the wall forming the passageway in front of the steps of the odeon. The essay traces the events that led to the discovery and subsequent storage made by Halbherr especially with the help of archaeologist L. Pernier and finally with the help of architect E. Stefani who designed a modern cover on the top of the ambulatory of the segments containing the inscription. This coverage was made to perform during the First World War on the basis of the Italian project from the Greek Government in order to protect the membership from possible war damage but especially from vandalism. The roof brick clay of the Laws of Gortyna still serves its function and ensures the use of the monument bearing witness to the preservation of Italian culture in Greece and more generally in the world. But in Sicily in the remains of the Villa del Casale in Piazza Armerina (Enna) its elegant protection (built in 1957) is representative of a whole period of culture of the Italian restoration is removed and replaced because it has not been able to make a ongoing maintenance is due. A bad example of conservation and management of a UNESCO monument from which arise after the work for the construction of new roofs an equally insulting to the archaeological heritage and scenic Italian and world.Settore ICAR/19 - Restauro
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L'intonaco Li Vigni nell'architettura del XX secolo a Palermo. Nuove conoscenze e applicazioni diagnostiche per la manutenzione

2013

Il saggio presenta lo studio degli intonaci formulati per imitare le pietre e i marmi naturali che si diffondono in Sicilia all’inizio del XX secolo ed evidenzia che le prime applicazioni e la diffusione delle nuove malte, anche nel resto dell’Italia, risentono delle sperimentazioni condotte in tutta l’Europa. Il contributo riassume i risultati di una rigorosa e capillare ricognizione tra i brevetti conservati presso l’Archivio Centrale dello Stato a Roma inerenti alle malte per il confezionamento dell’intonaco a “finta pietra”, ne analizza i contenuti in modo critico e pone in risalto i contatti culturali con le sperimentazioni dei materiali in atto nell’ambito dei grandi cantieri di resta…

The paper presents the study of the plaster formulated to imitate the natural stones and marbles that are popular in Sicily in the early twentieth century and points out that the first applications and the dissemination of new mortars also in the rest of Italy feels the influence of the experiments conducted throughout Europe . The contribution summarizes the results of a rigorous and thorough reconnaissance of patents kept in the Archivio Centrale dello Stato in Rome relating to mortars for plastering an artificial stone critically analyzes the content and emphasizes cultural contacts with the experiments on large-scale restoration projects in Italy and France in the late nineteenth century. The analysis of the architectural surfaces is developed with instrumental tests: the levels of adhesion of finishing surface are characterized in particular through a campaign of thermographic investigations and diagnosis is drawn to show that the consolidation of the layers and reintegration are interventions to be introduced ​​within the restoration project and maintenance program.Settore ICAR/19 - Restauro
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