Search results for "manifold"
showing 10 items of 415 documents
Simultaneous dissolution profiles of two drugs in pharmaceutical formulations by an FIA manifold
2002
Abstract This article deals with the simultaneous determination of dissolution profiles of two drugs with overlapped spectra, present in the same pharmaceutical formulation. The official procedure for the dissolution profile is adapted to the continuous-flow methodology; the dissolution vessel is connected to an FIA manifold, in which the sample aliquots from the dissolution vessel are treated in order to adjust to the suitable pH and dilution degree to be monitored. The resulting solution is injected into the carrier stream, an acetic acid–acetate buffer at pH 4.3 and forced to the flow-cell of the spectrophotometer. The simultaneous determination of both profiles is based on the first der…
Complex powers and non-compact manifolds
2002
We study the complex powers $A^{z}$ of an elliptic, strictly positive pseudodifferential operator $A$ using an axiomatic method that combines the approaches of Guillemin and Seeley. In particular, we introduce a class of algebras, ``extended Weyl algebras,'' whose definition was inspired by Guillemin's paper on the subject. An extended Weyl algebra can be thought of as an algebra of ``abstract pseudodifferential operators.'' Many algebras of pseudodifferential operators are extended Weyl algebras. Several results typical for algebras of pseudodifferential operators (asymptotic completeness, construction of Sobolev spaces, boundedness between apropriate Sobolev spaces, >...) generalize to…
Positive solutions for singular double phase problems
2021
Abstract We study the existence of positive solutions for a class of double phase Dirichlet equations which have the combined effects of a singular term and of a parametric superlinear term. The differential operator of the equation is the sum of a p-Laplacian and of a weighted q-Laplacian ( q p ) with discontinuous weight. Using the Nehari method, we show that for all small values of the parameter λ > 0 , the equation has at least two positive solutions.
On deformation of Poisson manifolds of hydrodynamic type
2001
We study a class of deformations of infinite-dimensional Poisson manifolds of hydrodynamic type which are of interest in the theory of Frobenius manifolds. We prove two results. First, we show that the second cohomology group of these manifolds, in the Poisson-Lichnerowicz cohomology, is ``essentially'' trivial. Then, we prove a conjecture of B. Dubrovin about the triviality of homogeneous formal deformations of the above manifolds.
The linearized Calderón problem on complex manifolds
2019
International audience; In this note we show that on any compact subdomain of a Kähler manifold that admits sufficiently many global holomorphic functions , the products of harmonic functions form a complete set. This gives a positive answer to the linearized anisotropic Calderón problem on a class of complex manifolds that includes compact subdomains of Stein manifolds and sufficiently small subdomains of Kähler manifolds. Some of these manifolds do not admit limiting Carleman weights, and thus cannot by treated by standard methods for the Calderón problem in higher dimensions. The argument is based on constructing Morse holo-morphic functions with approximately prescribed critical points.…
Making nonlinear manifold learning models interpretable: The manifold grand tour
2015
Smooth nonlinear topographic maps of the data distribution to guide a Grand Tour visualisation.Prioritisation of data linear views that are most consistent with data structure in the maps.Useful visualisations that cannot be obtained by other more classical approaches. Dimensionality reduction is required to produce visualisations of high dimensional data. In this framework, one of the most straightforward approaches to visualising high dimensional data is based on reducing complexity and applying linear projections while tumbling the projection axes in a defined sequence which generates a Grand Tour of the data. We propose using smooth nonlinear topographic maps of the data distribution to…
Active spike transmission in the neuron model with a winding threshold manifold
2012
International audience; We analyze spiking responses of excitable neuron model with a winding threshold manifold on a pulse stimulation. The model is stimulated with external pulse stimuli and can generate nonlinear integrate-and-fire and resonant responses typical for excitable neuronal cells (all-or-none). In addition we show that for certain parameter range there is a possibility to trigger a spiking sequence with a finite number of spikes (a spiking message) in the response on a short stimulus pulse. So active transformation of N incoming pulses to M (with M>N) outgoing spikes is possible. At the level of single neuron computations such property can provide an active "spike source" comp…
Integrable systems, Frobenius manifolds and cohomological field theories
2022
In this dissertation, we study the underlying geometry of integrable systems, in particular tausymmetric bi-Hamiltonian hierarchies of evolutionary PDEs and differential-difference equations.First, we explore the close connection between the realms of integrable systems and algebraic geometry by giving a new proof of the Witten conjecture, which constructs the string taufunction of the Korteweg-de Vries hierarchy via intersection theory of the moduli spaces of stable curves with marked points. This novel proof is based on the geometry of double ramification cycles, tautological classes whose behavior under pullbacks of the forgetful and gluing maps facilitate the computation of intersection…
Classification générique de synthèses temps minimales avec cible de codimension un et applications
1997
In this article we consider the problem of constructing the optimal closed loop control in the time minimal control problem, with terminal constraints belonging to a manifold of codimension one, for systems of the form v = X + uY, v ϵ R2, R3, |u| ≤ 1 under generic assumptions. The analysis is localized near the terminal manifold and is motivated by the problem of controlling a class of chemical systems.
Comparing the relative volume with a revolution manifold as a model
1993
Given a pair (P, M), whereM is ann-dimensional connected compact Riemannian manifold andP is a connected compact hypersurface ofM, the relative volume of (P, M) is the quotient volume(P)/volume(M). In this paper we give a comparison theorem for the relative volume of such a pair, with some bounds on the Ricci curvature ofM and the mean curvature ofP, with respect to that of a model pair\(\left( {\mathcal{P},\mathcal{M}} \right)\) where ℳ is a revolution manifold and\(\mathcal{P}\) a “parallel” of ℳ.