Search results for "mecA"
showing 10 items of 475 documents
How to deal with context? A context-mapping tool for quality and safety in nursing homes and homecare (SAFE-LEAD Context)
2019
Abstract Objective The objective of this paper is to develop a context-mapping tool (SAFE-LEAD Context) adapted to the nursing home and homecare setting. These two contexts represent a substantial variability, but studies focusing on the types and roles of contextual factors in quality and safety in these care settings are lacking. Results We conducted a step-wise collaborative design process consisting of mapping of key contextual factors as perceived by managers in Norwegian nursing homes and homecare, then created a draft tool discussed in a consortium workshop with co-researchers, and ran an international cross-country comparison. The SAFE-LEAD Context tool is inspired by the Consolidat…
Is the pelvis-thorax coordination a valuable outcome instrument to assess patients with Hip osteoarthritis?
2020
Objective: The evaluation of the disease severity in hip osteoarthritis (OA) patients being currently based on subjective instruments. It would be of interest to develop more objective instruments, for example based on gait analysis. The aims of this study were to explore if pelvis-thorax coordination parameters could be valuable instrument outcomes to achieve this evaluation by assessing their reliability, discriminant capacity and responsiveness. Methods: Three groups of subjects; healthy, hip OA patients with severe disease (defined as indication to surgery), hip OA patients with less severe disease (no indication to surgery) were included. Hip OA patients with severe disease were evalua…
Adaptive inputs in an interface for people with Dyskinetic Cerebral Palsy: Learning and usability
2016
This study concerns the difficulty in accessing computers faced by people with Dyskinetic Cerebral Palsy (DCP). Thus diminishing their opportunities to communicate or learn. This population usually needs an alternative input human-computer interface (HCI). The paper presents an alternative multimodal HCI that incorporates a head-mounted interface and superficial electromyography sensors (sEMG). The aim of the study is to assess the usability and the suitability of these two HCI devices. Six non-disabled subjects and ten subjects with DCP participated in the iterative process in which each test follows an improvement of an input. The results indicated that for both systems, the improvements …
El fomento de la mediación y de otros medios alternativos de justicia (también) en relación con la sustracción internacional de menores en Europa
2021
El decidido fomento de la mediación y de otros instrumentos MASC en el ámbito del Derecho de familia internacional constituye una constante, en los últimos tiempos, en el panorama comparado internacional. También en relación con aquellas disputas que involucran a menores. La UE no es ajena a este proceso y contribuye decididamente a éste. Aunque persisten dudas sobre la virtualidad real de estos mecanismos en la práctica diaria internacional.
Implicación de las vías Nrf2/HO-1 y NADPH oxidasa en los modelos experimentales de artritis y osteoporosis postmenópausicas.
2012
Hemos puesto a punto y caracterizado el modelo de artritis postmenopáusica mediante ovariectomía (OVX) y artritis inducida por colágeno (CIA). Además, hemos estudiado la influencia de la vía HO-1 en este modelo animal mediante la administración de tin protoporfirina IX (SnPP) (inhibidor reversible de HO-1) y de CORM-3 (molécula liberadora de CO), así como la influencia de la vía NADPH oxidasa mediante el empleo de ratones con una modificación genética en Ncf1 de manera que no producen especies reactivas del oxigeno por esta vía. En la caracterización del modelo de artritis postmenopáusica, OVX-CIA, se ha demostrado que el déficit de estrógenos potencia la respuesta inflamatoria y facilita e…
[1,2,3]Triazolo[1,5-a]piridinas y compuestos relacionados : aplicaciones en química supramolecular : actividad biológica
2013
Los heterociclos nitrogenados son moléculas clave dentro de numerosos campos científicos. En concreto, los triazoles han encontrado numerosas aplicaciones en química médica como antifúngicos (fluconazol, posaconazol), antidepresivos (trazodona) o anticancerígenos (triazoloacridonas). En este contexto se decidió sintetizar nuevos derivados de [1,2,3]triazolo[1,5-a]piridinas con el fin de explorar su capacidad de interaccionar con ADN y su actividad leishmanicida y antichagásica. Con este objetivo se ha utilizado la química clásica de las triazolopiridinas (reacción de litiación regioselectiva de este heterociclo, seguida de adición de un electrófilo), para obtener nuevos derivados con estruc…
ANALISI DI SICUREZZA DI SISTEMI DELL’IMPIANTO SPES
2014
Il progetto SPES prevede il bombardamento di un bersaglio in carburo di uranio con un fascio di protoni, in modo da generare, tramite reazione nucleare, specie radioattive all’interno del target. Le particelle radioattive generate vengono successivamente estratte, ionizzate, separate in massa ed accelerate come fascio di ioni radioattivo. Il presente lavoro di tesi ha riguardato lo studio di sicurezza di alcune unità dell'impianto SPES e si inserisce nell'ambito di una collaborazione di ricerca tra i Laboratori Nazionali di Legnaro ed il Dipartimento dell'Energia, sezione Nucleare, dell'Università degli Studi di Palermo. Tale attività ha comportato l'analisi sui componenti del sistema di pr…
On the variations of acoustic absorption peak with particle velocity in micro-perforated panels at high level of excitation.
2010
The acoustic behavior of micro-perforated panels (MPP) is studied theoretically and experimentally at high level of pressure excitation. A model based on Forcheimer's regime of flow velocity in the perforations is proposed. This model is valid at relatively high Reynolds numbers and low Mach numbers. The experimental method consists in measuring the acoustical pressure at three different positions in an impedance tube, the two measurement positions usually considered in an impedance tube and one measurement in the vicinity of the rear surface of the MPP. The impedance tube is equipped with a pressure driver instead of the usual loudspeaker and capable of delivering a high sound pressure lev…
Acoustic characterization of Silica aerogel clamped plates for perfect absorption purpose
2017
International audience; Silica aerogel has been widely studied as bulk material for its extremely low density and thermal conductivity. Plates or membranes made of this extremely soft materials exhibits interesting properties for sound absorption. A novel signal processing method for the characterization of an acoustic metamaterial made of silica aerogel clamped plates is presented. The acoustic impedance of a silica aerogel clamped plate is derived from the elastic theory for the flexural waves, while the transfer matrix method is used to model reflection and transmission coefficients of a single plate. Experimental results are obtained by using an acoustic impedance tube. The difference b…
Complex power distribution analysis in plates covered with passive constrained layer damping patches
2012
International audience; The vibration of a plate partially covered with a passive constrained layer damping (PCLD) patch is studied from an energetic point of view. The damped plate is excited by an acoustic plane wave. The study is done with a numerical two-dimensional multilayer plate model. Results of the present model are compared to those obtained with three-dimensional finite element models. It is shown that the present model gives accurate results, even for the layer's inner behavior. It is less expansive in terms of computational cost; hence, it can simulate efficiently the structure for higher frequencies. Mathematical formulas for complex mechanical power are presented, and the li…