Search results for "methods"

showing 10 items of 4526 documents

Functional and Prognostic Implications of the Main Pulmonary ArteryDiameter to Aorta Diameter Ratio from Chest Computed Tomography inKorean COPD Pati…

2016

Background The ratio of the diameter of the main pulmonary artery (mPA) to the diameter of the aorta (Ao) on chest computed tomography is associated with diverse clinical conditions. Herein, we determined the functional and prognostic implications of the mPA/Ao ratio in Korean chronic obstructive pulmonary disease (COPD) patients. Methods The study population comprised 226 chronic obstructive pulmonary disease patients from the Korean Obstructive Lung Disease cohort who underwent chest computed tomography. We analyzed the relationships between the clinical characteristics, including pulmonary function, echocardiography findings, St. George's Respiratory Questionnaire, 6-minute walking (6MW)…

MaleExacerbationPulmonologyPulmonary Functionlcsh:Medicine030204 cardiovascular system & hematologyPulmonary function testingDiagnostic RadiologyPulmonary Disease Chronic Obstructive0302 clinical medicineUltrasound ImagingMedicine and Health SciencesPulmonary Arterieslcsh:ScienceTomographyAortaCOPDMultidisciplinaryRadiology and ImagingArteriesMiddle AgedPrognosisObstructive lung diseaseEchocardiographyCardiologyFemaleAnatomyResearch Articlemedicine.medical_specialtyImaging TechniquesChronic Obstructive Pulmonary DiseaseCardiologyNeuroimagingPulmonary ArteryResearch and Analysis Methods03 medical and health sciencesFEV1/FVC ratioDiagnostic MedicineInternal medicinemedicine.arteryRepublic of KoreamedicineHumansAgedEmphysemaHeart Failurebusiness.industrylcsh:RBiology and Life SciencesOdds ratiomedicine.diseaseComputed Axial Tomography030228 respiratory systemHeart failurePulmonary arteryCardiovascular AnatomyBlood Vesselslcsh:QbusinessTomography X-Ray ComputedNeuroscience
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Semantic anomaly detection in school-aged children during natural sentence reading : A study of fixation-related brain potentials

2018

In this study, we investigated the effects of context-related semantic anomalies on the fixation-related brain potentials of 12–13-year-old Finnish children in grade 6 during sentence reading. The detection of such anomalies is typically reflected in the N400 event-related potential. We also examined whether the representation invoked by the sentence context extends to the orthographic representation level by replacing the final words of the sentence with an anomalous word neighbour of a plausible word. The eye-movement results show that the anomalous word neighbours of plausible words cause similar first-fixation and gaze duration reactions, as do other anomalous words. Similarly, we obser…

MaleEye MovementsPhysiologyVisual SystemSensory Physiologyschool-aged childrenSocial SciencesElectroencephalographylukeminen0302 clinical medicineParietal LobeMedicine and Health SciencesPsychologyAttentionChildEvoked Potentialsta515LanguageClinical NeurophysiologyP600Brain MappingMultidisciplinarymedicine.diagnostic_testQ05 social sciencesRBrainElectroencephalographySensory SystemsSemanticsElectrophysiologyBioassays and Physiological AnalysisBrain ElectrophysiologyPhysical SciencesMedicineAnomaly detectionFemaleAnatomyPsychologySentenceCognitive psychologyResearch ArticleAdolescentImaging TechniquesPermutationScienceNeurophysiologyNeuroimagingResearch and Analysis Methods050105 experimental psychology03 medical and health scienceskouluikäisetreadingmedicineReaction TimeHumanssemantic anomaly detection0501 psychology and cognitive sciencesScalpDiscrete MathematicsElectrophysiological TechniquesCognitive PsychologyBiology and Life SciencesLinguisticsFixation (psychology)Independent component analysisGazeN400Lexical SemanticsCombinatoricsCognitive ScienceConceptual SemanticsClinical MedicineHeadanomaliat030217 neurology & neurosurgeryMathematicsNeurosciencePLoS ONE
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When Geometry Constrains Vision: Systematic Misperceptions within Geometrical Configurations.

2016

International audience; How accurate are we in reproducing a point within a simple shape? This is the empirical question we addressed in this work. Participants were presented with a tiny disk embedded in an empty circle (Experiment 1 and 3) or in a square (Experiment 2). Shortly afterwards the disk vanished and they had to reproduce the previously seen disk position within the empty shape by means of the mouse cursor, as accurately as possible. Several loci inside each shape were tested. We found that the space delimited by a circle and by a square is not homogeneous and the observed distortion appears to be consistent across observers and specific for the two tested shapes. However, a com…

MaleEye MovementsVisionPhysiologyVisual SystemVector SpacesSensory PhysiologySocial Scienceslcsh:Medicine[ SCCO.PSYC ] Cognitive science/Psychology050109 social psychologyGeometrySquare (algebra)SymmetryForm perceptionMedicine and Health SciencesPsychologyAttentionlcsh:ScienceMathematicsMultidisciplinaryExperimental Design05 social sciencesSensory SystemsPattern Recognition VisualResearch Design[ SCCO.NEUR ] Cognitive science/Neuroscience[SCCO.PSYC]Cognitive science/PsychologyPhysical SciencesSensory PerceptionFemaleResearch ArticleAdultGeometryResearch and Analysis Methods050105 experimental psychologyYoung AdultPosition (vector)DistortionHumans0501 psychology and cognitive sciencesPoint (geometry)Vision Ocularshape perception perceptual center perceptual force vector field perceptual distortion visual mislocalization Gestalt eye movements[SCCO.NEUR]Cognitive science/Neurosciencelcsh:RCognitive PsychologyBiology and Life SciencesNull (physics)Form PerceptionAlgebraRadiiLinear AlgebraSpace PerceptionContour lineLinear ModelsCognitive Sciencelcsh:QSymmetry (geometry)MathematicsPhotic StimulationNeurosciencePLoS ONE
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A method for automatic forensic facial reconstruction based on dense statistics of soft tissue thickness.

2019

In this paper, we present a method for automated estimation of a human face given a skull remain. The proposed method is based on three statistical models. A volumetric (tetrahedral) skull model encoding the variations of different skulls, a surface head model encoding the head variations, and a dense statistic of facial soft tissue thickness (FSTT). All data are automatically derived from computed tomography (CT) head scans and optical face scans. In order to obtain a proper dense FSTT statistic, we register a skull model to each skull extracted from a CT scan and determine the FSTT value for each vertex of the skull model towards the associated extracted skin surface. The FSTT values at p…

MaleFOS: Computer and information sciencesDatabases FactualComputer Vision and Pattern Recognition (cs.CV)Statistics as TopicComputer Science - Computer Vision and Pattern RecognitionSocial SciencesDiagnostic RadiologyMathematical and Statistical TechniquesImage Processing Computer-AssistedMedicine and Health SciencesMusculoskeletal SystemTomographyPrincipal Component AnalysisRadiology and ImagingStatisticsQRClinical Laboratory Sciences004Physical SciencesMedicineFemaleAnatomic LandmarksAnatomyResearch ArticleAdultBiometrySoft TissuesImaging TechniquesScienceNeuroimagingNoseResearch and Analysis MethodsDiagnostic MedicineHumansStatistical MethodsSkeletonForensicsSkullBiology and Life SciencesComputed Axial TomographyBiological TissueFaceMultivariate AnalysisForensic AnthropologyLaw and Legal SciencesTomography X-Ray ComputedHeadMathematicsNeurosciencePLoS ONE
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FACTORIAL INVARIANCE OF PERSONALITY RATINGS

1969

Kuusinen, J. Factorial invariance of personality ratings. Scand. J. Psychol., 1969, 10, 33–44—Three studies employing the same set of 33 personality rating scales are described. (I) Five factor structures of the scales, derived from ratings of five groups of stimuli, were compared. (2) One subject rated different personality concepts three times at one week's intervals. (3) 12 individual factor structures were compared to the factor structure computed from peer ratings of a group of 39 subjects. Results: (a) the factor structure of the scales was largely independent of stimuli, (b) the structure for an individual was stable, (c) the group structure represented the individual's structure, (d…

MaleFactorial invarianceAdolescentGroup (mathematics)media_common.quotation_subjectGeneral MedicinePersonality AssessmentFactor structureDevelopmental psychologyGroup structureArts and Humanities (miscellaneous)Rating scaleMethodsDevelopmental and Educational PsychologyHumansPersonalityFemaleFactor Analysis StatisticalSet (psychology)PsychologyGeneral Psychologymedia_commonScandinavian Journal of Psychology
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How work and family caregiving responsibilities interplay and affect registered dietitian nutritionists and their work: A national survey.

2021

Healthcare professionals provide paid care at work and potentially have caregiving responsibilities outside of work; work responsibilities in addition to child and/or elder care is considered double- or triple-duty care. Employees may experience conflict and/or enrichment as their work and family responsibilities interface. This study’s purpose is to explore the work and family interface of Registered Dietitian Nutritionists (RDNs), determine the prevalence of work-family conflict and enrichment, and identify characteristics associated with higher work-family conflict and enrichment scores. A survey instrument assessing caregiving responsibilities and work-family conflict and enrichment was…

MaleFamily ConflictEconomicsSocial SciencesBurnoutSurveys0302 clinical medicineSociologySurveys and QuestionnairesMedicine and Health SciencesPsychology030212 general & internal medicineElder careHuman FamiliesBurnout ProfessionalMultidisciplinary05 social sciencesQRMiddle AgedProfessionsWork (electrical)CaregiversResearch DesignMedicineJob satisfactionFemalePsychologyResearch ArticleEmploymentAdultPolitical ScienceHealth PersonnelSciencePsychological StressAffect (psychology)Research and Analysis MethodsJob Satisfaction03 medical and health sciencesNursing0502 economics and businessMental Health and PsychiatryHumansFamilyNutritionistsNutritionAgedLabor StudiesSurvey ResearchLife satisfactionBiology and Life SciencesUnited StatesDietHealth CareLabor EconomicsPeople and PlacesRegistered dietitianPopulation GroupingsSurvey instrumentDelivery of Health Care050203 business & managementPLoS ONE
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Transforming RNA-Seq Data to Improve the Performance of Prognostic Gene Signatures

2014

Gene expression measurements have successfully been used for building prognostic signatures, i.e for identifying a short list of important genes that can predict patient outcome. Mostly microarray measurements have been considered, and there is little advice available for building multivariable risk prediction models from RNA-Seq data. We specifically consider penalized regression techniques, such as the lasso and componentwise boosting, which can simultaneously consider all measurements and provide both, multivariable regression models for prediction and automated variable selection. However, they might be affected by the typical skewness, mean-variance-dependency or extreme values of RNA-…

MaleGene Expressionlcsh:Medicinecomputer.software_genreBioinformaticslcsh:ScienceExtreme value theoryMultidisciplinaryMultivariable calculusStatisticsRegression analysisGenomicsPrognosisKidney NeoplasmsNeoplasm ProteinsLeukemia Myeloid AcuteMedicineProbability distributionFemaleSequence AnalysisAlgorithmsResearch ArticleStatistical DistributionsRiskBoosting (machine learning)Clinical Research DesignFeature selectionBiostatisticsBiologyMachine learningMolecular GeneticsGenome Analysis ToolsCovariateHumansStatistical MethodsGene PredictionBiologyCarcinoma Renal CellProbabilityClinical GeneticsSequence Analysis RNAbusiness.industrylcsh:RPersonalized MedicineModelingComputational BiologyProbability TheorySurvival AnalysisSkewnessMultivariate AnalysisRNAlcsh:QArtificial intelligenceGenome Expression AnalysisTranscriptomebusinesscomputerMathematicsPLoS ONE
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Novel loci for childhood body mass index and shared heritability with adult cardiometabolic traits

2020

The genetic background of childhood body mass index (BMI), and the extent to which the well-known associations of childhood BMI with adult diseases are explained by shared genetic factors, are largely unknown. We performed a genome-wide association study meta-analysis of BMI in 61,111 children aged between 2 and 10 years. Twenty-five independent loci reached genome-wide significance in the combined discovery and replication analyses. Two of these, located nearNEDD4LandSLC45A3, have not previously been reported in relation to either childhood or adult BMI. Positive genetic correlations of childhood BMI with birth weight and adult BMI, waist-to-hip ratio, diastolic blood pressure and type 2 d…

MaleGenetic-variationNedd4 Ubiquitin Protein LigasesPooled AnalysisBlood Pressure0302 clinical medicineHuman geneticsMendelian RandomizationYoung adultChildhealth care economics and organizationsBody mass indexAdiposityGenetics & Heredity0303 health sciencesStatistics1184 Genetics developmental biology physiologyGenomicsadulto3. Good healthCardiovascular DiseasesChild PreschoolPhysical SciencesMenarchegenetic-variationpresión sanguíneaMonosaccharide Transport ProteinsGenetic locieducationenfermedades cardiovascularesProstate-specific AntigenGenetic correlation03 medical and health sciencesSDG 3 - Good Health and Well-beingDiabetes MellitusGeneticsHumansprostate-specific antigenStatistical MethodsMolecular BiologyEcology Evolution Behavior and Systematicschildhood0604 Genetics[SDV.GEN]Life Sciences [q-bio]/GeneticsScience & TechnologyEarly Growth Genetics ConsortiumBiology and Life SciencesComputational Biologynutritional and metabolic diseasesSingle nucleotide polymorphismsMendelian Randomization AnalysisBiological TissueDiabetes Mellitus Type 2estudio de asociación genómica completagenetic factorsmendelian randomizationanálisis de la aleatorización mendelianaproteínas de transporte de monosacáridosBody mass index030217 neurology & neurosurgeryMathematicsDemographyDevelopmental BiologyCardiovascular RiskCancer ResearchobesityPhysiologyhumanosadolescenteOverweightQH426-470Genome-wide association studiesWaist–hip ratioMathematical and Statistical TechniquesMedicine and Health Sciencesbody mass index (BMI)Genetics of diseaseGenetics (clinical)2. Zero hungeradiposityMetaanalysisPhysiological ParametersConnective Tissue/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingFemalemedicine.symptomAnatomypooled analysisLife Sciences & BiomedicineResearch ArticleAdultcardiovascular riskAdolescentBirth weightmenarquiaAdipose tissueBiology3121 Internal medicineResearch and Analysis MethodsmedicineoverweightGenetic Predisposition to DiseaseObesity030304 developmental biologyMenarcheWaist-Hip Ratioíndice de masa corporalBody WeightCardiometabolic Risk Factorspredisposición genética a la enfermedadHeritabilityOverweightGenome Analysisyoung-adultsGenome-wide Associationíndice cintura-caderaYoung-adultsgenome-wide associationGenome-Wide Association StudyPLoS genetics
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Soft Tissue Response to Titanium Abutments with Different Surface Treatment: Preliminary Histologic Report of a Randomized Controlled Trial

2016

The aim of this preliminary prospective RCT was to histologically evaluate peri-implant soft tissues around titanium abutments treated using different cleaning methods. Sixteen patients were randomized into three groups: laboratory customized abutments underwent Plasma of Argon treatment (Plasma Group), laboratory customized abutments underwent cleaning by steam (Steam Group), and abutments were used as they came from industry (Control Group). Seven days after the second surgery, soft tissues around abutments were harvested. Samples were histologically analyzed. Soft tissues surrounding Plasma Group abutments predominantly showed diffuse chronic infiltrate, almost no acute infiltrate, with …

MaleGenetics and Molecular Biology (all)Pathologymedicine.medical_specialtyPlasma GasesArticle SubjectCleaning methodsImmunology and Microbiology (all)Statistical differencelcsh:MedicineDental AbutmentsBiochemistryGeneral Biochemistry Genetics and Molecular BiologySoft Tissue Responselaw.inventionPlasma Gase03 medical and health sciences0302 clinical medicineRandomized controlled trialDental AbutmentslawCollagen; Female; Humans; Male; Middle Aged; Mouth; Plasma Gases; Titanium; Wound Healing; Dental AbutmentsHumansMedicineddc:610TitaniumMouthWound HealingDental AbutmentBiochemistry Genetics and Molecular Biology (all)General Immunology and Microbiologybusiness.industrySignificant differencelcsh:RSoft tissue030206 dentistryGeneral MedicineMiddle AgedClinical StudyFemaleCollagenWound healingbusinessHuman030215 immunologyBiochemistry; Genetics and Molecular Biology (all); Immunology and Microbiology (all)BioMed Research International
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Mobility Modification Alleviates Environmental Influence on Incident Mobility Difficulty among Community-Dwelling Older People: A Two-Year Follow-Up …

2016

Background Environmental barriers increase risk for mobility difficulties in old age. Mobility difficulty is preceded by a phase where people try to postpone a difficulty through mobility modification. We studied whether perceived environmental mobility barriers outdoors correlate with mobility modification and mobility difficulty, predict development of mobility difficulty over a two-year follow-up, and whether mobility modification alleviates the risk for difficulty. Methods At baseline, 848 people aged 75–90 were interviewed face-to-face. Telephone follow-up interviews were conducted one (n = 816) and two years (n = 761) later. Environmental barriers to mobility were self-reported using …

MaleGerontologyActivities of daily livingMedical DoctorsympäristöPhysiologyHealth Care Providerslcsh:MedicineWalkingolder peopleEndocrinologyMathematical and Statistical Techniques0302 clinical medicineSurveys and QuestionnairesActivities of Daily LivingMedicine and Health SciencesBiomechanics030212 general & internal medicinelcsh:ScienceAged 80 and overMultidisciplinaryCognitive NeurologyFollow up studiesta3141mobilityProfessionsliikkuvuusNeurologyPhysical SciencesRegression AnalysisFemaleIndependent LivingGait AnalysisPsychologyenvironmentStatistics (Mathematics)Research ArticleBiotechnologymedicine.medical_specialtyEndocrine DisordersCognitive NeuroscienceResearch and Analysis MethodsOdds03 medical and health sciencesPhysical medicine and rehabilitationPhysiciansDiabetes MellitusmedicineHumansMobility LimitationStatistical MethodsSelf reportAgedBehaviorBiological Locomotionlcsh:RBiology and Life SciencesHealth CareMobility LimitationMetabolic DisordersPeople and PlacesCognitive ScienceMedical Devices and EquipmentPopulation Groupingslcsh:QSelf ReportOlder peopleMathematics030217 neurology & neurosurgeryIndependent livingFollow-Up StudiesNeuroscience
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