Search results for "miR"

Phase-specific modulation of cortical motor output during movement observation.

2001

The effects of different phases of an observed movement on the modulation of cortical motor output were studied by means of transcranial magnetic stimulation (TMS). A video-clip of a reaching-grasping action was shown and single TMS pulses were delivered during its passive observation, Times of cortical stimulation were related to the phases of the shown movement, locking them to the appearance of specific kinematic landmarks. The amplitude of the motor evoked potentials (MEPs) induced by TMS in the first dorsal interosseus (FDI) muscle was modulated by the amount of the observed finger aperture. The presence of such an effect is consistent with the notion of a mirror neuron system in premo…

Pro-inflammatory status is not a limit for longevity: case report of a Sicilian centenarian

2020

Most studies on centenarians represent them as the best model of ageing. They are defined “delayers”, if they exhibit age-related diseases between 80 and 99 years, “survivors” if they show clinically demonstrable diseases before the age of 80 years, and “escapers” when they attain their 100th year of life without any common age-associated pathologies.

miR-126-3p and miR-21-5p as Hallmarks of Bio-Positive Ageing; Correlation Analysis and Machine Learning Prediction in Young to Ultra-Centenarian Sici…

2022

Human ageing can be characterized by a profile of circulating microRNAs (miRNAs), which are potentially predictors of biological age. They can be used as a biomarker of risk for age-related inflammatory outcomes, and senescent endothelial cells (ECs) have emerged as a possible source of circulating miRNAs. In this paper, a panel of four circulating miRNAs including miR-146a-5p, miR-126-3p, miR-21-5p, and miR-181a-5p, involved in several pathways related to inflammation, and ECs senescence that seem to be characteristic of the healthy ageing phenotype. The circulating levels of these miRNAs were determined in 78 healthy subjects aged between 22 to 111 years. Contextually, extracellular miR-1…

Narcissus plays video games

2015

Abstract Two phenomena of our time have fascinated the general public and the scientific community alike: (a) narcissism as a personality characteristic with important implications for daily social functioning, and (b) the (vast) use of digital media such as video games. But how are these phenomena related to one another? To investigate this question, we administered an online survey to 2,891 individuals to assess their levels of narcissistic admiration and rivalry (NARQ; Back et al., 2013) and their video-gaming activities (frequency of playing, reasons for playing, preferred game genre and role). Results revealed that these narcissism dimensions were differentially related to video gaming…

Trait Empathy associated with Agreeableness and rhythmic entrainment in a spontaneous movement to music task: Preliminary exploratory investigations

2017

The simulation theory of empathy suggests that we use motor processing to empathise, through modelling the actions of others. Similarly, research into embodied music cognition posits that music, particularly musical rhythm, is perceived as a motor stimulus. In both cases, the human Mirror Neuron System (MNS) is put forward as a potential underlying mechanism. If this is the case, some overlap may exist between the ability to empathise with others, and the ability to perceive rhythm in music. The present study investigated this relationship indirectly, through the study of individual differences in Trait Empathy and rhythmic entrainment. Undergraduate students ( N = 237) completed a questio…

Optimal timing of power line rights-of-ways management for the conservation of butterflies

2012

Habitat loss, fragmentation, and degradation are the main threats to biodiversity. Human activities also create new habitat types that might fulfil ecological requirements for a variety of species. This study investigates whether the vegetation clearing (=shrub and tree cutting) on drained mire patches on power line rights-of-ways (ROWs) keep plant communities in an early successional stage and thus provide habitats for mire specialist and non-mire butterflies. It was further studied what would be the optimal clearing interval in terms of butterfly species richness and abundance. The results show that tree height, especially the height of birch, increases linearly over the 7-year period fol…

Mujer, poder político y democracia paritaria. “Mujer y representación política institucional en la Comunidad Valenciana. 1977-1995. 2 parte.

2014

Mujer, poder político y democracia paritaria. “Mujer y representación política institucional en la Comunidad Valenciana. 1977-1995. 2 parte. En esta segunda parte se recogen las mujeres que han formado parte de la Administración Local (alcaldesas, diputadas provinciales y FVMP), en los sindicatos, asi como en otras instituciones: Consell Valencià de Cultura, Consejo de Radiotelevisión Valenciana, Sindicatura de Agravios, Academia Valenciana de la Lengua, universidades, direcciones de partidos políticos, y otras organizaciones de la Comunidad Valenciana. “Mujer y representación política institucional en la Comunidad Valenciana. 1977-1995. Diputadas, ministras y cargos institucionales” es la …

Kampania wielkopolska i kujawska Chryzostoma Jana Niemiry Gniazdowskiego

2020

W pracy przedstawiony został przebieg kampanii wielkopolsko-kujawskiej, która trwała dziewięć miesięcy, od lutego do października 1716 r. Przyjętym przez tarnogrodzian celem było rozszerzenie związku konfederackiego na Wielkopolskę właściwą, a następnie Kujawy i Pomorze. Poprowadzona została przez regimentarza, pułkownika Chryzostoma Jana Niemirę Gniazdowskiego - jeśli nie najzdolniejszego, to niewątpliwe najbardziej rzutkiego, skorego do podejmowania ryzykownych akcji, a przy tym skutecznego dowódcę konfederackiego. Jego przeciwnikiem były wojska królewskie złożone z oddziałów saski i polskich, dowodzone przez generała porucznika Kaspra von Seidlitz oraz generałów majorów Aleksandra Dietri…

A descendent tropical Landau–Ginzburg potential for $\mathbb{P}^2$

2016

Enumerative Aspects of the Gross-Siebert Program

2015

For the last decade, Mark Gross and Bernd Siebert have worked with a number of collaborators to push forward a program whose aim is an understanding of mirror symmetry. In this chapter, we’ll present certain elements of the “Gross-Siebert” program. We begin by sketching its main themes and goals. Next, we review the basic definitions and results of two main tools of the program, logarithmic and tropical geometry. These tools are then used to give tropical interpretations of certain enumerative invariants. We study in detail the tropical pencil of elliptic curves in a toric del Pezzo surface. We move on to a basic illustration of mirror symmetry, Gross’s tropical construction for \(\mathbb{P…