Search results for "milieu"

showing 10 items of 19813 documents

Development and Validation of Hepamet Fibrosis Scoring System-A Simple, Noninvasive Test to Identify Patients With Nonalcoholic Fatty Liver Disease W…

2020

HEPAmet Registry.

AdultLiver CirrhosisMalemedicine.medical_specialtySteatosis[SDV]Life Sciences [q-bio]BiopsyLikelihood ratios in diagnostic testingGastroenterologySeverity of Illness IndexDecision Support Techniques03 medical and health sciences0302 clinical medicineFibrosisNon-alcoholic Fatty Liver DiseasePositive predicative valueInternal medicineNonalcoholic fatty liver diseaseHOMAMedicineHumansComputingMilieux_MISCELLANEOUSAged2. Zero hungerNASH FIBROSISHepatologymedicine.diagnostic_testReceiver operating characteristicbusiness.industryPrognostic FactorGastroenterologyOdds ratioMiddle Agedmedicine.diseasePrognosis3. Good healthCross-Sectional StudiesDiagnostic ToolCirrhosisLiver030220 oncology & carcinogenesisLiver biopsyDiagnostic odds ratio030211 gastroenterology & hepatologyFemalebusinessClinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association
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A deep learning framework for automatic diagnosis of unipolar depression.

2019

Abstract Background and purpose In recent years, the development of machine learning (ML) frameworks for automatic diagnosis of unipolar depression has escalated to a next level of deep learning frameworks. However, this idea needs further validation. Therefore, this paper has proposed an electroencephalographic (EEG)-based deep learning framework that automatically discriminated depressed and healthy controls and provided the diagnosis. Basic procedures In this paper, two different deep learning architectures were proposed that utilized one dimensional convolutional neural network (1DCNN) and 1DCNN with long short-term memory (LSTM) architecture. The proposed deep learning architectures au…

AdultMale020205 medical informaticsComputer science[SDV]Life Sciences [q-bio]Health Informatics02 engineering and technologyElectroencephalographyMachine learningcomputer.software_genreConvolutional neural network03 medical and health sciencesAutomation0302 clinical medicineDeep LearningEeg data0202 electrical engineering electronic engineering information engineeringmedicineHumans030212 general & internal medicineComputingMilieux_MISCELLANEOUSDepression (differential diagnoses)Depressive Disordermedicine.diagnostic_testbusiness.industryDeep learningElectroencephalographyCase-Control StudiesFemaleArtificial intelligenceNeural Networks ComputerbusinesscomputerInternational journal of medical informatics
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Whole genome paired-end sequencing elucidates functional and phenotypic consequences of balanced chromosomal rearrangement in patients with developme…

2019

BackgroundBalanced chromosomal rearrangements associated with abnormal phenotype are rare events, but may be challenging for genetic counselling, since molecular characterisation of breakpoints is not performed routinely. We used next-generation sequencing to characterise breakpoints of balanced chromosomal rearrangements at the molecular level in patients with intellectual disability and/or congenital anomalies.MethodsBreakpoints were characterised by a paired-end low depth whole genome sequencing (WGS) strategy and validated by Sanger sequencing. Expression study of disrupted and neighbouring genes was performed by RT-qPCR from blood or lymphoblastoid cell line RNA.ResultsAmong the 55 pat…

AdultMale0301 basic medicineCandidate geneAdolescentDNA Copy Number VariationsDevelopmental Disabilities030105 genetics & heredityGenomeTranslocation GeneticStructural variationChromosome BreakpointsStructure-Activity RelationshipYoung Adult03 medical and health sciencessymbols.namesakeposition effectGeneticsHumansChildGeneGenetic Association StudiesGenetics (clinical)Paired-end tagComputingMilieux_MISCELLANEOUSchromosomal rearrangementsChromosome AberrationsGene RearrangementWhole genome sequencingGeneticsSanger sequencingwhole genome sequencingbiologystructural variationInfantNFIXPhenotype030104 developmental biology[SDV.GEN.GH]Life Sciences [q-bio]/Genetics/Human geneticsintellectual disabilityChild Preschoolbiology.proteinsymbolsFemaleBiomarkers
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A meta-analysis of 120 246 individuals identifies 18 new loci for fibrinogen concentration

2015

Genome-wide association studies have previously identified 23 genetic loci associated with circulating fibrinogen concentration. These studies used HapMap imputation and did not examine the X-chromosome. 1000 Genomes imputation provides better coverage of uncommon variants, and includes indels. We conducted a genome-wide association analysis of 34 studies imputed to the 1000 Genomes Project reference panel and including similar to 120 000 participants of European ancestry (95 806 participants with data on the X-chromosome). Approximately 10.7 million single-nucleotide polymorphisms and 1.2 million indels were examined. We identified 41 genome-wide significant fibrinogen loci ; of which, 18 …

AdultMale0301 basic medicineNetherlands Twin Register (NTR)Single-nucleotide polymorphismGenome-wide association studyBiologyPolymorphism Single NucleotideWhite People03 medical and health sciencesINDEL MutationGenetics/dk/atira/pure/keywords/cohort_studies/netherlands_twin_register_ntr_Humans1000 Genomes ProjectInternational HapMap ProjectIndelMolecular BiologyGenetics (clinical)ComputingMilieux_MISCELLANEOUSAgedGenetic associationAged 80 and overGeneticsAssociation Studies ArticlesFibrinogen[SDV.MHEP.HEM]Life Sciences [q-bio]/Human health and pathology/HematologyGeneral MedicineMiddle AgedGenetic architecture030104 developmental biologyGenetic LociFemaleGENOME-WIDE ASSOCIATION ; C-REACTIVE PROTEIN ; CARDIOVASCULAR-DISEASE ; CIRCULATING FIBRINOGEN ; GENETIC ARCHITECTURE ; VARIANTS ; DESIGN ; HEMOSTASIS ; RESOURCE ; HEALTHImputation (genetics)Genome-Wide Association Study
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Decision-Making Skills Moderate the Relationship between Psychological and Physical Pain with Suicidal Behavior in Depressed Patients

2019

International audience

AdultMale050103 clinical psychologyAdolescentDecision MakingMEDLINEPainSuicide AttemptedYoung Adult03 medical and health sciences[SCCO]Cognitive science0302 clinical medicineHumansMedicine0501 psychology and cognitive sciencesYoung adultApplied PsychologyComputingMilieux_MISCELLANEOUSAged[SDV.NEU.PC]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Psychology and behaviorDepressionbusiness.industry05 social sciencesGeneral MedicineMiddle Aged16. Peace & justice030227 psychiatryPsychiatry and Mental healthClinical PsychologySuicidal behaviorPain psychologyFemalebusinessClinical psychologyMESH: Decision making; Depression/psychology; Pain/psychology; Suicide Attempt/psychology; Young Adult
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Technical, tactical and movement analysis of men's professional tennis on hard courts.

2018

Background There is very little information in tennis relating performance to both the movement of the players and the effectiveness of their shots. This study aimed to identify differences between winners and losers in the volume and intensity of their movements, as well as in the effectiveness of their shots. Methods Matches (N.=8) at the 2011 ATP 500 tournament in Valencia (Spain) were recorded and analyzed using SAGIT, a computerized vision-tracking system. Data were split into points for movement analysis, and into games for stroke analysis. Results Players winning points used more offensive strategies and spent more time in the offensive zone than point losers. They also forced point …

AdultMale060101 anthropologyMovementComputingMilieux_PERSONALCOMPUTINGOffensivePhysical Therapy Sports Therapy and RehabilitationAdvertising030229 sport sciences06 humanities and the artsAthletic PerformanceMovement analysis03 medical and health sciencesYoung Adult0302 clinical medicineSpainTennisHumans0601 history and archaeologyOrthopedics and Sports MedicineTournamentSports and Recreational FacilitiesPsychologyThe Journal of sports medicine and physical fitness
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Type I interferons as the potential mechanism linking mRNA COVID-19 vaccines to Bell's palsy

2021

Therapies - Sous presse. Epreuves corrigees par l'auteur. Disponible en ligne depuis le mardi 13 avril 2021

AdultMale2019-20 coronavirus outbreakCoronavirus disease 2019 (COVID-19)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)COVID-19 vaccines030226 pharmacology & pharmacyArticle03 medical and health sciencesPharmacovigilance0302 clinical medicineBell's palsyPhase 3 clinical trialsBell PalsymedicineType I interferonsHumansBell's palsyPharmacology (medical)Potential mechanismComputingMilieux_MISCELLANEOUSAgedCOVID-19 coronavirus disease 2019Vaccines SyntheticMessenger RNASARS-CoV-2business.industryCOVID-19Bell’s palsyMiddle Agedmedicine.diseaseVirologymRNA messenger RNA3. Good healthInterferon Type IFemale[SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologiebusiness
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Selective deficits in episodic feeling of knowing in ageing: A novel use of the general knowledge task

2015

Failure to recall an item from memory can be accompanied by the subjective experience that the item is known but currently unavailable for report. The feeling of knowing (FOK) task allows measurement of the predictive accuracy of this reflective judgement. Young and older adults were asked to provide answers to general knowledge questions both prior to and after learning, thus measuring both semantic and episodic memory for the items. FOK judgements were made at each stage for all unrecalled responses, providing a measure of predictive accuracy for semantic and episodic knowledge. Results demonstrated a selective effect of age on episodic FOK resolution, with older adults found to have impa…

AdultMaleAgingMemory Episodicmedia_common.quotation_subjectEmotionsExperimental and Cognitive Psychology[SHS]Humanities and Social SciencesTask (project management)Developmental psychologyJudgmentYoung Adult[SCCO]Cognitive scienceArts and Humanities (miscellaneous)Memory[ SHS ] Humanities and Social SciencesMetamemoryDevelopmental and Educational PsychologyHumansLearningSemantic memoryGeneral knowledgeEpisodic memoryComputingMilieux_MISCELLANEOUSAgedmedia_commonRecallAutobiographical memoryRecognition PsychologyGeneral MedicineAwarenessMiddle AgedSemanticsKnowledgeFeelingMental RecallFemale[ SCCO ] Cognitive sciencePsychologyCognitive psychologyActa Psychologica
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Symmetry, averageness, and feature size in the facial attractiveness of women

2004

International audience; Female facial attractiveness was investigated by comparing the ratings made by male judges with the metric characteristics of female faces. Three kinds of facial characteristics were considered: facial symmetry, averageness, and size of individual features. The results suggested that female face attractiveness is greater when the face is symmetrical, is close to the average, and has certain features (e.g., large eyes, prominent cheekbones, thick lips, thin eyebrows, and a small nose and chin). Nevertheless, the detrimental effect of asymmetry appears to result solely from the fact that an asymmetrical face is a face that deviates from the norm. In addition, a factor …

AdultMaleAttractivenessVisual perceptionmedia_common.quotation_subjectExperimental and Cognitive PsychologyAsymmetry050105 experimental psychologyBeautyJudgment03 medical and health sciences0302 clinical medicineSocial DesirabilityArts and Humanities (miscellaneous)Developmental and Educational PsychologymedicineHumans0501 psychology and cognitive sciencesComputingMilieux_MISCELLANEOUSmedia_common[SCCO.NEUR]Cognitive science/Neuroscience05 social sciences030206 dentistryGeneral Medicine[SCCO.LING]Cognitive science/LinguisticsChinmedicine.anatomical_structureFacial AsymmetryAveragenessFaceFace (geometry)Beauty[SCCO.PSYC]Cognitive science/PsychologyVisual PerceptionFemalePsychologySocial psychologyFacial symmetry
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A new approach to examine the relationships between sensory and gas chromatography-olfactometry data using generalized procrustes analysis applied to…

2003

Six French Chardonnay wines were submitted to both sensory and combined headspace/gas chromatography-olfactometry analyses. The detection frequencies allowed five hierarchical levels to be distinguished: P25, the odorant areas (OAs) having a detection frequencyor =25% (the complete olfactogram without the odor noise); P40,or =40%; P55,or =55%; P70,or =70%; and P85,or =85%. Moreover, the detection frequencies were analyzed to distinguish 21 discriminative OAs. Wines tested by sensory analysis and the headspace samples analyzed by gas chromatography-olfactometry (GC-O) were described by a heterogeneous vocabulary distributed into nine overall classes of descriptors. The new statistical treatm…

AdultMaleChromatography GasSensory systemWine01 natural sciencesSensory analysisCorrespondence analysis0404 agricultural biotechnologyDiscriminative modelOlfactometry[SDV.IDA]Life Sciences [q-bio]/Food engineeringHumansComputingMilieux_MISCELLANEOUSMathematicsChromatographybusiness.industry010401 analytical chemistryGeneralized Procrustes analysisPattern recognition04 agricultural and veterinary sciencesGeneral Chemistry[SDV.IDA] Life Sciences [q-bio]/Food engineering040401 food science0104 chemical sciencesOdorTasteOdorantsFemaleArtificial intelligenceGas chromatographyFranceVolatilizationGeneral Agricultural and Biological Sciencesbusiness
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