Search results for "mines"

showing 10 items of 2609 documents

Catalytic Enantioselective Aza-Reformatsky Reaction with Cyclic Imines

2016

A catalytic highly enantioselective aza-Reformatsky reaction with cyclic aldimines and ketimines for the synthesis of chiral b-amino esters with good yields and excellent enantioselectivities is reported.Areadily available diaryl prolinol is used as a chiral ligand, ZnMe2 as a zinc source and ethyl iodoacetate as reagent in the presence of air atmosphere. The reaction with cyclic ketimines generates a quaternary stereocenter with excellent levels of enantioselectivity. Furthermore, five-membered N-sulfonyl ketimines were used as electrophiles with good enantiomeric excesses, under the optimized reaction conditions. Moreover, several chemical transformations were performed with the chiral b-…

AldimineEthyl iodoacetateBeta-amino ester010402 general chemistry01 natural sciencesCatalysisReaccions químiquesStereocenterchemistry.chemical_compoundCatàlisiAsymmetric catalysisOrganic chemistryheterocyclic compoundsReformatsky reactionchemistry.chemical_classification010405 organic chemistryOrganic ChemistryChiral ligandEnantioselective synthesisGeneral Chemistry0104 chemical sciencesProlinolCyclic ketiminesZincchemistryReformatsky reactionFISICA APLICADAReagentQuímica orgànicaChemistry - A European Journal
researchProduct

Luminescence of silica glass containing aluminum oxide

2004

Abstract Optical properties of silica glass with different doping of Al 2 O 3 up to 1.5 mol% were studied. Alumina stimulates creation of a luminescence centers with specific band at 3.3 eV. A new band at 8.2 eV appears in luminescence excitation spectra. There is transport of energy to other luminescence centers associated with an impurity (Ag, Ce) at this energy. Alumina stimulates creation of E′ centers under γ-irradiation beside trapped hole on AlO 4 tetrahedron as well as creation of a silicon related oxygen deficient center (SiODC) under cathodoexcitation. Visually, the samples look inhomogeneous even after γ-irradiation. The explanation could be heterogeneity of the samples. Alumina …

Alkali ionsElectrolysisMaterials scienceSilica glassSiliconDopingAnalytical chemistrychemistry.chemical_elementMineralogyCondensed Matter PhysicsElectronic Optical and Magnetic Materialslaw.inventionchemistryImpuritylawMaterials ChemistryCeramics and CompositesLuminescenceAluminum oxideJournal of Non-Crystalline Solids
researchProduct

Organocatalytic enantioselective functionalization of indoles in the carbocyclic ring with cyclic imines

2019

[EN] An organocatalytic enantioselective functionalization in the carbocyclic ring of indoles with benzoxathiazine 2,2-dioxides is described using a quinine-derived bifunctional organocatalyst. This aza-Friedel-Crafts reaction provides 4-indolyl, 5-indolyl and 7-indolyl sulfamidate derivatives in good yields (up to 99%) and with moderate to high enantioselectivities (up to 86% ee).

Alkylation02 engineering and technologyAlkylation010402 general chemistryRing (chemistry)01 natural sciencesHydroxyindolesCatalysisKetiminesReaccions químiqueschemistry.chemical_compoundMaterials ChemistryFriedel-Crafts reactionBifunctionalFriedel–Crafts reactionConstructionAsymmetric-SynthesisChemistryInhibitorsEnantioselective synthesisGeneral Chemistry021001 nanoscience & nanotechnologyCombinatorial chemistry0104 chemical sciencesFISICA APLICADASurface modification0210 nano-technologyQuímica orgànicaDerivatives
researchProduct

A Combination of Visible-Light Organophotoredox Catalysis and Asymmetric Organocatalysis for the Enantioselective Mannich Reaction of Dihydroquinoxal…

2019

[EN] An enantioselective photooxidative Mannich reaction of dihydroquinoxalinones with ketones by the merger of organophotoredox and asymmetric organocatalysis is described. This protocol features very mild reaction conditions using simple and cheap catalysts (Eosin Y and (S)-Proline) for the synthesis of chiral quinoxaline derivatives with good to high yields (up to 94%) and excellent enantioselectivities (up to 99% ee).

AlkylationActivation010402 general chemistry01 natural sciencesBiochemistryCatalysisReaccions químiqueschemistry.chemical_compoundQuinoxalineCatàlisiComplexesTertiary-AminesAcidOrganic chemistryPhysical and Theoretical ChemistryEosin YFunctionalizationMannich reactionReaction conditions010405 organic chemistryOrganic ChemistryEnantioselective synthesisMethodology0104 chemical sciencesPhotoredox catalysisEfficientchemistryOrganocatalysisFISICA APLICADAHydrogenationQuímica orgànicaVisible spectrum
researchProduct

A Highly Active System for the Metal-Free Aerobic Photocyanation of Tertiary Amines with Visible Light: Application to the Synthesis of Tetraponerine…

2015

A highly efficient metal-free catalytic system for the aerobic photocyanation of tertiary amines with visible light is reported. The use of air as terminal oxidant offers an improved safety profile compared with pure oxygen, the used compact fluorescent lamp (CFL) light sources are highly economical, and no halogenated solvents are required. This system not only proves to be effective for a wide variety of trialkylamines, pharmaceuticals, and alkaloids but remarkably also allows the lowest catalyst loading (0.00001 mol% or 0.1 ppm) ever reported for an organic dye. Bruylants reactions and C-alkylation/decyanations were performed on the obtained α-aminonitriles to demonstrate the postfunctio…

AlkylationLightMolecular Structure010405 organic chemistryChemistryOrganic ChemistryTotal synthesisActive systemsGeneral ChemistryAlkylationIsoquinolines010402 general chemistry01 natural sciencesCatalysis0104 chemical sciencesCatalysisAlkaloidsMetal freeMetalsPhotocatalysisOrganic chemistryMoleculeAminesOxidation-ReductionVisible spectrumChemistry - A European Journal
researchProduct

Design, Synthesis, and Biological Evaluation of Novel Fluorinated Ethanolamines

2011

The preparation of novel fluorinated allylamines and their use as key fragments for the stereoselective synthesis of hydroxyethyl secondary amine (HEA)-type peptidomimetics is described. Our strategy employs chiral sulfinyl imines as synthesis intermediates, by treatment of hemiaminal precursors with two equivalents of vinylmagnesium bromide. The subsequent oxidation of the allylic amines to the corresponding epoxides was achieved by treatment with methyl(trifluoromethyl)dioxirane. Finally, epoxide ring opening with a range of nitrogen nucleophiles provided a library of HEA-derived peptidomimetics with a phenyldifluoromethylene moiety. The biological evaluation of these derivatives revealed…

Allylic rearrangementHalogenationPhthalic AcidsSulfonium CompoundsEpoxideCatalysisNocardiaantimicrobialsMycobacteriumchemistry.chemical_compoundDioxiraneNucleophileAnti-Infective AgentsfluorineMoietyOrganic chemistryAspartic Acid EndopeptidasesHumansEthanolamineTrifluoromethylMolecular StructureAntimicrobialsOrganic ChemistryEthanolaminesStereoisomerismBACE1FluorineGeneral ChemistrychemistryEthanolaminespeptidomimeticsHemiaminalethanolaminesEpoxy CompoundsIminesPeptidomimeticsAmyloid Precursor Protein Secretases
researchProduct

Novel Approach for Asymmetric Synthesis of Fluorinated β-Amino Sulfones and Allylic Amines

2003

[reaction: see text] Enantiomerically pure gamma-fluoroalkyl beta-amino sulfones are readily synthesized in three steps starting from fluorinated imidoyl chlorides and arylmethyl sulfones. A complementary two-step sequence starting from chiral fluorinated beta-amino sulfoxides has also been developed. To illustrate the application of this procedure, a new method for the synthesis of alpha-fluoroalkyl allylic amines in optically pure form involving a Julia methylenation-desulfonylation reaction is presented.

Allylic rearrangementHydrocarbons FluorinatedChemistryorganic chemicalsOrganic ChemistryEnantioselective synthesisStereoisomerismGeneral MedicineCombinatorial chemistryBiochemistryAllyl CompoundsOrganic chemistrySulfonesAminesPhysical and Theoretical ChemistryOrganic Letters
researchProduct

Thermostimulated processes in statically and dynamically disordered luminescent solids

1993

Abstract Trap spectra depending on the concentration of defects in crystalline KBr-T1, LiF-Mg, Ti, A1 2 O 3 and glassy Na 2 O·SiO 2 are investigated. The nature of inhomogeneous broadening and continuous distribution of traps over activation energies at sufficiently high defect concentrations is considered. Impurity hopping controlled recombination of electronic excitations is observed. The presence of enlarged values of process activation energies and frequency factors is discussed in terms of the concept of dynamic disorder, taking into account the fluctuational changes in both the perfectpart and the structure of defects in the solid at high temperatures.

Aluminium oxidesCondensed matter physicsImpurityChemistryInorganic chemistryGeneral EngineeringCharge carrierActivation energyTrappingLuminescenceThermoluminescenceSpectral lineNuclear Tracks and Radiation Measurements
researchProduct

The F-type centres in YAG crystals

2001

The comparative study of optical properties of thermochemically reduced undoped YAG (Y3Al5O12) crystals is reported. A particular type of the centres often observed in YAG crystals synthesized as w...

Aluminium oxidesNuclear and High Energy PhysicsRadiationMaterials sciencePhotoluminescenceOpticsbusiness.industryAnalytical chemistryGeneral Materials ScienceX ray irradiationCondensed Matter PhysicsLuminescencebusinessRadiation Effects and Defects in Solids
researchProduct

Optically detected magnetic resonance studied via the blue luminescence of Ti-doped

1998

The UV-excited blue and green luminescence bands of Ti:sapphire are characterized by ODMR. These emission bands are attributed to two centres, which show very similar properties and are created as a result of a charge-transfer transition of an electron from to ions. In both centres, the d electron of and the hole of are strongly coupled and form triplet states. Doublet systems can be ruled out as sources of the blue-green luminescence. The angular dependence of the ODMR can be explained with an appropriate spin Hamiltonian assuming orthorhombic local symmetry. The orientation of the principal axes of the g-tensor and the crystal-field tensor, found for both centres, suggest that the hole is…

Aluminium oxidesNuclear magnetic resonanceChemistryLocal symmetryDopingSapphireGeneral Materials ScienceOrthorhombic crystal systemElectronCondensed Matter PhysicsLuminescenceMolecular physicsIonJournal of Physics: Condensed Matter
researchProduct