Search results for "ministry"
showing 10 items of 256 documents
Detection Of Genomic Variants Of SARS-CoV-2 Circulating In Wastewater By High-Throughput Sequencing
2021
The use of SARS-CoV-2 metagenomics in wastewater can allow the detection of variants circulating at community level. After comparing with clinical databases, we identified three novel variants in the spike gene, and six new variants in the spike detected for the first time in Spain. We finally support the hypothesis that this approach allows the identification of unknown SARS-CoV-2 variants or detected at only low frequencies in clinical genomes.
Portales educativos : la producción de materiales didácticos digitales
2018
El objetivo principal de este artículo es conocer cómo se organiza la producción de los materiales didácticos digitales de creación propia de portales institucionales de recursos educativos, tomando como referencia la perspectiva de sus principales responsables. En concreto, se analiza el caso del repositorio institucional de recursos de la Comunidad Autónoma de Canarias, Ecoescuela 2.0; y del portal de recursos educativos en abierto Procomún (Ministerio de Educación, Cultura y Deporte). Con este estudio se pretende dar respuesta a distintas cuestiones relacionadas con la autoría de los materiales, el proceso y desarrollo, así como los criterios que establecen los portales institucionales p…
Information sources and knowledge on vaccination in a population from southern Italy: The ESCULAPIO project
2016
Vaccine knowledge of the general population is shaped by different information sources and strongly influences vaccination attitudes and uptake. The CCM-Italian Ministry of Health ESCULAPIO project attempted to identify the role of such information sources, in order to address adequate strategies to improve information on vaccines and vaccine preventable diseases. In the present study, data on 632 adults from Southern Italy regarding information sources were collected, and their perceived and actual knowledge on vaccinations were compared and analyzed in relation to socio-demographic characteristics and information sources. The main reported reference sources were general practitioners (GPs…
Neddylation inhibition ameliorates steatosis in NAFLD by boosting hepatic fatty acid oxidation via the DEPTOR-mTOR axis
2021
Objective Neddylation is a druggable and reversible ubiquitin-like post-translational modification upregulated in many diseases, including liver fibrosis, hepatocellular carcinoma, and more recently, non-alcoholic fatty liver disease (NAFLD). Herein, we propose to address the effects of neddylation inhibition and the underlying mechanisms in pre-clinical models of NAFLD. Methods Hepatic neddylation measured by immunohistochemical analysis and NEDD8 serum levels measured by ELISA assay were evaluated in NAFLD clinical and pre-clinical samples. The effects of neddylation inhibition by using a pharmacological small inhibitor, MLN4924, or molecular approaches were assessed in isolated mouse hep…
Poor mothers, unhealthy children: the transmission of health inequalities in the INMA study, Spain
2019
Background The health of pregnant women and their fetuses are especially sensitive to socioeconomic conditions. This study analyzes the impact of maternal socioeconomic status (SES), evaluated by occupation and maternal education level, in preterm births (PTBs) and in small for gestational age (SGA) fetuses, considering the effect of the potential mediating factors on the SES and birth outcomes. Methods A total of 2497 mother/newborn dyads from the INMA-Spain project were studied. We examined maternal occupation and education in relation to PTB and SGA along with covariate data, using logistic regression analysis. Adjusted models for each of the outcome variables in relation to SES indicato…
Evidence for association between structural variants in lissencephaly-related genes and executive deficits in schizophrenia or bipolar patients from …
2008
There is evidence for an association between structural variants in genes for lissencephaly, which are involved in neuronal migration, and prefrontal cognitive deficits in schizophrenia and bipolar patients. On the basis of these intriguing findings, we analyzed 16 markers located in the lissencephaly critical region (LCR in chromosome 17p13.3) in 124 schizophrenic, 56 bipolar, and 141 healthy individuals. All recruits were from a Spanish population isolate of Basque origin that is characterized by low genetic heterogeneity. In addition, we examined whether structural genomic variations in the LCR were associated with executive cognition. Twenty-three patients (12.8%), but none of the contr…
Effects of functional resistance training on fitness and quality of life in females with chronic nonspecific low-back pain.
2018
BACKGROUND: Exercise is important as adjuvant in the chronic low back pain (CLBP) treatment. Functional training could involve benefits for low back pain (LBP) patients. OBJECTIVE: To evaluate the effects of a 12-week period of functional resistance training on health-related quality of life (HRQOL), disability, body pain, and physical fitness in CLBP females. METHODS: Nineteen females CLBP were recruited according to Paris Task Force on Back Pain criteria. Participants were randomly assigned to an exercise group (EG); and a control group (CG). Subjects were tested at baseline and at week 12 after 24 sessions, 2 days per week. Body pain was assessed using visual analog scale (VAS), disabili…
Older and Younger Adults Perform Similarly in an Iterated Trust Game
2021
This work was supported by the Spanish Ministry of Education, Culture and Sports, with pre-doctoral FPU fellowship FPU14/07106 to MT, and the Spanish Ministry of Economy and Competitiveness, with research projects PSI2014-52764-P and PSI2017-84926-P to JL. This research is part of MT’s thesis dissertation under the supervision of JL.
High-resolution stimulated Raman spectroscopy and analysis of the ν 1 band of osmium tetroxide
2012
D.B.P. and R.Z.M. acknowledge the financial support of the Ministry of Science and Innovation through research grant no. FIS2009-08069.
Energy and economic analysis and feasibility of retrofit actions in Italian residential historical buildings
2016
Abstract The application of retrofit actions to existing building stocks can improve the energy performance of the residential sector. In this context, particular attention should be given to historical buildings, which represent a large part of the Italian building stock. To improve the energy performance of them, adequate retrofit actions must be applied. Many studies and regulations have focused on identifying the best refurbishment measures. However, the selection of these measures is difficult due to restrictive regulations, which are dictated by the Ministry of Cultural Heritage and Activities, high retrofit costs, and variable climate zones. Thus, energy renovations in Italian buildi…