Search results for "modelling and simulation"
showing 10 items of 97 documents
Robust dynamical pattern formation from a multifunctional minimal genetic circuit.
2010
Abstract Background A practical problem during the analysis of natural networks is their complexity, thus the use of synthetic circuits would allow to unveil the natural mechanisms of operation. Autocatalytic gene regulatory networks play an important role in shaping the development of multicellular organisms, whereas oscillatory circuits are used to control gene expression under variable environments such as the light-dark cycle. Results We propose a new mechanism to generate developmental patterns and oscillations using a minimal number of genes. For this, we design a synthetic gene circuit with an antagonistic self-regulation to study the spatio-temporal control of protein expression. He…
Strain gradient plasticity, strengthening effects and plastic limit analysis
2010
Abstract Within the framework of isotropic strain gradient plasticity, a rate-independent constitutive model exhibiting size dependent hardening is formulated and discussed with particular concern to its strengthening behavior. The latter is modelled as a (fictitious) isotropic hardening featured by a potential which is a positively degree-one homogeneous function of the effective plastic strain and its gradient. This potential leads to a strengthening law in which the strengthening stress, i.e. the increase of the plastically undeformed material initial yield stress, is related to the effective plastic strain through a second order PDE and related higher order boundary conditions. The plas…
A second strain gradient elasticity theory with second velocity gradient inertia – Part I: Constitutive equations and quasi-static behavior
2013
Abstract A multi-cell homogenization procedure with four geometrically different groups of cell elements (respectively for the bulk, the boundary surface, the edge lines and the corner points of a body) is envisioned, which is able not only to extract the effective constitutive properties of a material, but also to assess the “surface effects” produced by the boundary surface on the near bulk material. Applied to an unbounded material in combination with the thermodynamics energy balance principles, this procedure leads to an equivalent continuum constitutively characterized by (ordinary, double and triple) generalized stresses and momenta. Also, applying this procedure to a (finite) body s…
Fast relaxation phenomena and slow mode in extended thermodynamics of superfluids
2003
A macroscopic monofluid model of liquid helium II which is based on extended thermodynamics was formulated in previous works, both in the presence and in the absence of dissipative phenomena. In all these studies, the time evolution of the nonequilibrium stress tensor was neglected, putting the relaxation times @t"0 and @t"2 of the nonequilibrium pressure and of the stress deviator equal to zero. In this work, the time evolution of these fields is not neglected and the complete model with 14 fields is studied, in the linear approximation. The propagation of waves is studied and a dispersion relation of degree 14 is obtained. The solutions of this equation are carried out, perturbing the sol…
Comparing the use of ERA5 reanalysis dataset and ground-based agrometeorological data under different climates and topography in Italy
2022
Study region: The study region is represented by seven irrigation districts distributed under different climate and topography conditions in Italy. Study focus: This study explores the reliability and consistency of the global ERA5 single levels and ERA5-Land reanalysis datasets in predicting the main agrometeorological estimates commonly used for crop water requirements calculation. In particular, the reanalysis data was compared, variable-by-variable (e.g., solar radiation, R; air temperature, T; relative humidity, RH; wind speed, u; reference evapotranspiration, ET), with in situ agrometeorological observations obtained from 66 automatic weather stations (2008–2020). In addition, the pre…
Free energy and states of fractional-order hereditariness
2014
AbstractComplex materials, often encountered in recent engineering and material sciences applications, show no complete separations between solid and fluid phases. This aspect is reflected in the continuous relaxation time spectra recorded in cyclic load tests. As a consequence the material free energy cannot be defined in a unique manner yielding a significative lack of knowledge of the maximum recoverable work that can extracted from the material. The non-uniqueness of the free energy function is removed in the paper for power-laws relaxation/creep function by using a recently proposed mechanical analogue to fractional-order hereditariness.
A new invariant-based method for building biomechanical behavior laws - Application to an anisotropic hyperelastic material with two fiber families
2013
Abstract In this article, we present a general constructive and original approach that allows us to calculate the invariants associated with an anisotropic hyperelastic material made of two families of collagen fibers. This approach is based on mathematical techniques from the theory of invariants: • Definition of the material symmetry group. • Analytical calculation of a set of generators using the Noether’s theorem. • Analytical calculation of an integrity basis. • Comparison between the proposed invariants and the classical ones.
Geostatistical computing of acoustic maps in the presence of barriers
2009
Acoustic maps are the main diagnostic tools used by authorities for addressing the growing problem of urban acoustic contamination. Geostatistics models phenomena with spatial variation, but restricted to homogeneous prediction regions. The presence of barriers such as buildings introduces discontinuities in prediction areas. In this paper we investigate how to incorporate information of a geographical nature into the process of geostatistical prediction. In addition, we study the use of a Cost-Based distance to quantify the correlation between locations.
Conceptual design and simulation of a water Cherenkov muon veto for the XENON1T experiment
2014
XENON is a direct detection dark matter project, consisting of a time projection chamber (TPC) that uses xenon in double phase as a sensitive detection medium. XENON100, located at the Laboratori Nazionali del Gran Sasso (LNGS) in Italy, is one of the most sensitive experiments of its field. During the operation of XENON100, the design and construction of the next generation detector (of ton-scale mass) of the XENON project, XENON1T, is taking place. XENON1T is being installed at LNGS as well. It has the goal to reduce the background by two orders of magnitude compared to XENON100, aiming at a sensitivity of $2 \cdot 10^{-47} \mathrm{cm}^{\mathrm{2}}$ for a WIMP mass of 50 GeV/c$^{2}$. With…
Comparison between simulated and observed LHC beam backgrounds in the ATLAS experiment at E beam =4 TeV
2018
Results of dedicated Monte Carlo simulations of beam-induced background (BIB) in the ATLAS experiment at the Large Hadron Collider (LHC) are presented and compared with data recorded in 2012. During normal physics operation this background arises mainly from scattering of the 4 TeV protons on residual gas in the beam pipe. Methods of reconstructing the BIB signals in the ATLAS detector, developed and implemented in the simulation chain based on the FLUKA Monte Carlo simulation package, are described. The interaction rates are determined from the residual gas pressure distribution in the LHC ring in order to set an absolute scale on the predicted rates of BIB so that they can be compared qua…