Search results for "nAChR"
showing 10 items of 20 documents
Herodotus’ awareness of the Peloponnesian War
2020
AbstractThis article aims to discuss the relationship between Herodotus and Thucydides. New scholarly trends date the composition of Herodotus’Historiesto 413 BC, or even later, against high chronology of 431, and suggest Herodotus’ use of Thucydides’ narrative. Herodotus’ debt to Thucydides has been suggested by scholars either cautiously or boldly. This examination will show cases where Herodotus is alluding to events of the Peloponnesian War or even responding to Thucydides’ narrative. In fact, anachronisms, presentisms, and allusions to Thucydides’ text can be found throughout Herodotus’ narrative. We will explore the reasons for Herodotus’ engaging with the events of that War, conjectu…
Book Clubs and Book Commerce
2019
In the twentieth century, cumulative millions of readers received books by mail from clubs like the Book-of-the-Month Club, the Book Society or Bertelsmann Club. This Element offers an introduction to book clubs as a distribution channel and cultural phenomenon, and shows that book clubs and book commerce are linked inextricably. It argues that a global perspective is necessary to understand the cultural and economic impact of book clubs in the twentieth and into the twenty-first century. It also explores central reasons for book club membership, condensing them into four succinct categories: convenience, community, concession and, most importantly, curation. This title is also available as…
Increased sensitivity of the neuronal nicotinic receptor alpha-2 subunit causes familial epilepsy with nocturnal wandering and ictal fear
2006
Sleep has traditionally been recognized as a precipitating factor for some forms of epilepsy, although differential diagnosis between some seizure types and parasomnias may be difficult. Autosomal dominant frontal lobe epilepsy is characterized by nocturnal seizures with hyperkinetic automatisms and poorly organized stereotyped movements and has been associated with mutations of the α4 and β2 subunits of the neuronal nicotinic acetylcholine receptor. We performed a clinical and molecular genetic study of a large pedigree segregating sleep-related epilepsy in which seizures are associated with fear sensation, tongue movements, and nocturnal wandering, closely resembling nightmares and sleep …
Diffusion of Drone Journalism: the Case of Finland, 2011-2020
2020
This article details Finnish news organizations’ adoption of drones for journalistic purposes from 2011 to 2020. The theoretical starting point of the article is Rogers’ (1962) diffusion of innovations theory, which explains how new ideas and technologies spread in societies. The main empirical data for the study were derived from a phone survey conducted among the 80 most popular newspapers in Finland. The findings reveal that drone journalism in Finland has already diffused from a few pioneering organizations to a large number of newsrooms, including regional, mid-sized newspapers. Most of the newspapers are either using in-house drones, buying commissioned images, or using both strategie…
The overstated generational gap in online news use? A consolidated infrastructural perspective
2021
Recent research by Taneja et al. suggested that digital infrastructures diminish the generational gap in news use by counteracting preference structures. We expand on this seminal work by arguing that an infrastructural perspective requires overcoming limitations of highly aggregated web tracking data used in prior research. We analyze the individual browsing histories of two representative samples of German Internet users collected in 2012 ( N = 2970) and 2018 ( N = 2045) and find robust evidence for a smaller generational gap in online news use than commonly assumed. While short news website visits mostly demonstrated infrastructural factors, longer news use episodes were shaped more by …
Mustan auringon paketti
2015
Black Sun Package. Myths and Melancholy in Irene Larsen’s Collection Sortsolsafari In this article, I analyse how the Sami poet Irene Larsen rewrites Sami oral tradition and mythology in her collection Sortsolsafari (2013, “Black Sun Safari”). I discuss how Larsen’s work differs from the mainstream of contemporary Sami poetry and other indigenous literatures. Sortsolsafari has postmodernist features, which seldom are found in Sami literature. Larsen situates mythological elements in present-day reality: a Sami goddess uses a sewing machine and a shaman logs on to the Internet. These anachronisms create a comical effect. Instead of nostalgia and anti-colonialism, which traditionally characte…
¿Un transhumanismo nietzscheano? Sobre la parcialidad del alegato
2020
espanolEl articulo analiza desde una perspectiva critica las tentativas de interpretar a Nietzsche como un precursor del transhumanismo. Tras una breve contextualizacion del fecundo debate en torno a Nietzsche y el transhumanismo, se evalua el caracter fraccional o parcial del alegato de Stefan Sorgner en favor de un “transhumanismo nietzscheano”. Despues, se investiga la tension entre humanidad, la superacion del ser humano y su cria en los escritos de Nietzsche. Una vez ejecutado este analisis, y sin animo de caer en el anacronismo, se sostiene que Nietzsche anticipa ciertamente un germen de la idea de post-humanidad, en su critica de la cultura humanista y en su invitacion a transformar …
How social network sites and other online intermediaries increase exposure to news
2020
Research has prominently assumed that social media and web portals that aggregate news restrict the diversity of content that users are exposed to by tailoring news diets toward the users’ preferences. In our empirical test of this argument, we apply a random-effects within–between model to two large representative datasets of individual web browsing histories. This approach allows us to better encapsulate the effects of social media and other intermediaries on news exposure. We find strong evidence that intermediaries foster more varied online news diets. The results call into question fears about the vanishing potential for incidental news exposure in digital media environments.
Visualization practices in Scandinavian newsrooms : a qualitative study
2017
The visualization of numeric data is becoming an important element in journalism, and new tools and platforms make the development of data visualization in the news discourse accelerate. In this paper we present an interview study investigating this development in Scandinavian newsrooms. Editorial leaders, data journalists, graphic designers, and developers in 10 major news organizations in Norway, Sweden and Denmark inform the study on a range of issues concerning visual practices and experiences in the newsrooms. Elements of tension are revealed on issues concerning the role and effect of complex, exploratory data visualizations and concerning the role of ordinary journalists in the produ…
Nicotine-induced FGF-2 mRNA in rat brain is preserved during aging
2004
Indirect trophic actions of nicotine on brain during aging are suggested from observations describing nicotine as a cognitive enhancer, increasing vigilance and improving learning and memory, and both in vitro and in vivo models have demonstrated neuroprotective effects of nAChR agonists. Previously, we have reported that an acute intermittent (-)nicotine treatment significantly increases fibroblast growth factor-2 (FGF-2) mRNA and protein in several brain regions of rat brain. The present study was designed to analyse if nicotine-induced FGF-2 expression in the rat brain was preserved during aging. Using in situ hybridization and quantitative RNase protection assay the present paper report…