Search results for "noms"

showing 10 items of 114 documents

A rapid separation of the four major deoxynucleosides and deoxyinosine by high-pressure liquid cation-exchange chromatography

1973

DeoxyribonucleasesChromatographyIon exchangePhosphoric Diester HydrolasesVenomsChemistryDeoxyribonucleotidesIon chromatographyBiophysicsPhosphoric Diester HydrolasesDeoxyribonucleosidesDNACell BiologyAlkaline PhosphataseChromatography Ion ExchangeBiochemistryMicrococcusHigh pressureMethodsPressureMolecular BiologyNucleic acid analogueAnalytical Biochemistry
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Synthesis and comparison of the antiinflammatory activity of manoalide and cacospongionolide B analogues.

1998

We have synthesized analogues of two naturally occurring antiinflammatory marine compounds, manoalide and cacospongionolide B, containing a pyranofuranone moiety which is considered the pharmacophoric group. The two compounds, and hence their analogues, differ in the presence or absence in the dihydropyran ring of an hemiacetal function which was considered essential to irreversibly inactivate phospholipase A 2 (PLA 2 ). The two series of compounds were tested for their inhibitory effects on secretory PLA 2 belonging to the groups I, II, and III, and the activities were found to be similar in both series, irrespective of the presence or absence of the additional hemiacetal function. In addi…

DihydropyranStereochemistrySwineCarrageenanChemical synthesisPhospholipases ACell Linechemistry.chemical_compoundManoalideMiceStructure-Activity RelationshipCytosol4-ButyrolactoneDrug DiscoveryMoietyAnimalsEdemaHumansEnzyme InhibitorsPancreasPyranschemistry.chemical_classificationElapid VenomsPhospholipase AbiologyMolecular StructureTerpenesAnti-Inflammatory Agents Non-SteroidalSynovial MembraneBee VenomsKineticsPhospholipases A2chemistryEnzyme inhibitorDrug Designbiology.proteinMolecular MedicineHemiacetalFemaleLactoneJournal of medicinal chemistry
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A peptide inhibiting the collagen binding function of integrin alpha2I domain.

1999

Integrin alpha2 subunit forms in the complex with the beta1 subunit a cell surface receptor binding extracellular matrix molecules, such as collagens and laminin-1. It is a receptor for echovirus-1, as well. Ligands are recognized by the special "inserted" domain (I domain) in the integrin alpha2 subunit. Venom from a pit viper, Bothrops jararaca, has been shown to inhibit the interaction of platelet alpha2beta1 integrin with collagen because of the action of a disintegrin/metalloproteinase named jararhagin. The finding that crude B. jararaca venom could prevent the binding of human recombinant ralpha2I domain to type I collagen led us to study jararhagin further. Synthetic peptides represe…

EGF-like domainIntegrinIntegrin alpha2PeptideBiologyBiochemistryPeptides CyclicEuropiumAntigens CDCrotalid VenomsDisintegrinHumansAmino Acid SequenceMolecular BiologyRGD motifDNA Primerschemistry.chemical_classificationBase SequenceCell MembraneMetalloendopeptidasesCell BiologyCyclic peptideRecombinant ProteinsBiochemistrychemistryJararhaginbiology.proteinCollagenBinding domainThe Journal of biological chemistry
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ESR Spectra o f Normal Human Serum after Treatment with Complement Activating Agents*

1980

Abstract We describe the appearance of a free-radical signal in the ESR spectrum of normal human serum incubated with several complement activating agents. The intensity of this signal is dependent of dose of activating agents, time and temperature. Signals elicited by different complement activators differ in morphology and kinetics. Inhibition by treatment with EDTA and the presence of the signal in activated C 6-deficient rabbit serum suggest that the con-vertase forming steps of complement activation (C2 to 5) could be the source of free-radical containing molecules.

Elapid VenomsMaleFree RadicalsChemistryKineticsElectron Spin Resonance SpectroscopyZymosanBlood ProteinsComplement System ProteinsGeneral Biochemistry Genetics and Molecular BiologyComplement systemComplement (complexity)Esr spectraBiochemistryHumansFemaleComplement ActivationAfter treatmentZeitschrift für Naturforschung C
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Activation of bee venom phospholipase A2 through a peptide-enzyme complex

1995

AbstractPhospholipase A2 activation by membrane-bound peptides was investigated in order to understand the role of the membrane-induced conformation on activation, and to examine the occurrence of a peptide-enzyme complex at the lipid/water interface. For the peptides studies, bee venom phospholipase A2 was stimulated regardless of the membrane-bound conformation (α-helix, β-sheet or random coil). Using antisera raised against melittin, we were able to demonstrate the occurrence of a calcium-dependent complex involving the enzyme, phospholipid substrate, and peptide.

Enzyme complexProtein ConformationMolecular Sequence DataBiophysicsPhospholipidPeptidePhospholipaseBiochemistrycomplex mixturesAbellesMelittinAntibodiesPhospholipases AProtein Structure Secondarychemistry.chemical_compoundEnzyme activatorPhospholipase A2Structural BiologyGeneticsAnimalsAmino Acid SequencePhospholipaseMolecular BiologyPeptide sequencePeptide-enzyme complexchemistry.chemical_classificationbiologyCircular DichroismMembrane ProteinsMelittinCell BiologyMelittenEnzyme ActivationBee VenomsPhospholipases A2chemistryBiochemistryLiposomesbiology.proteinPèptidsPeptides
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Physicochemical characterization of the fifth (C5), sixth (C6), seventh (C7), eighth (C8) and ninth (C9) component of guinea pig complement.

1971

A physicochemical characterization of the purified guinea pig complement components C5 to C9 is given. For this purpose the sedimentation rate, the diffusion coefficient, the molecular weight and the isoelectric point were determined and compared with the values already known for the guinea pig and human complement system. For the determination of the physicochemical parameters gel filtration on Sephadex G-200, ultracentrifugation applying a sucrose density gradient and thin-layer isoelectric focusing were used. By comparing the values of the human and guinea pig complement a remarkable similarity is shown.

ErythrocytesDensity gradientChemical PhenomenaImmunologySize-exclusion chromatographyGuinea PigsBiologyGuinea pigHemoglobinsCentrifugation Density GradientImmunology and AllergyAnimalsHumansChromatographyIsoelectric focusingChemistry PhysicalVenomsElectric ConductivitySnakesComplement System ProteinsCatalaseComplement systemMolecular WeightIsoelectric pointSephadexImmunoglobulin GImmunologyChromatography GelUltracentrifugeIsoelectric FocusingEuropean journal of immunology
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L'origen, la identitat i el nom de la llengua catalana segons Constantí Llombart

2020

Resum: Al segle xix se situa l’inici de la filologia romànica, i cada vegada més eruditscataloguen i estudien les diferents llengües romàniques i la llengua catalana en particular.Progressivament, en aquest període els erudits i escriptors de la catalanofonia realitzenafirmacions sobre el seu origen —compartit amb la llengua occitana o independent des del’inici—, la seua identitat —subordinada a l’occità o autònoma com la resta de llengüesromàniques— i el nom amb què cal referir-s’hi. Aquest treball analitza els coneixements del’escriptor valencià Constantí Llombart (1848–1893) sobre l’origen, la identitat i el nomde la llengua catalana. Paraules clau: Constantí Llombart, segle xix, Orige…

General Earth and Planetary SciencesCatalà Etimologia NomsGeneral Environmental Science
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Living alone, receiving help, helplessness, and inactivity are strongly related to risk of undernutrition among older home-dwelling people

2012

Solveig T Tomstad1, Ulrika Söderhamn2, Geir Arild Espnes3, Olle Söderhamn21Department of Social Work and Health Science, Faculty of Sciences and Technology Management, NTNU, Trondheim, Norway and Centre for Caring Research – Southern Norway, Faculty of Health and Sport Sciences, University of Agder, Grimstad, Norway; 2Centre for Caring Research – Southern Norway, Faculty of Health and Sport Sciences, University of Agder, Grimstad, Norway; 3Research Centre for Health Promotion and Resources HiST-NTNU, Department of Social Work and Health Science, Faculty of Social Sciences and Technology Management, NTNU, Trondheim, NorwayBackground: Being at risk of und…

GerontologySense of CoherenceHome dwellingLearned helplessnessInternational Journal of General MedicinehjemmeboendeNorgeVDP::Medical disciplines: 700::Health sciences: 800::Nutrition: 811tverrsnittforebyggingkartleggingmattverrsnittstudieself-caremedicineeldreegenomsorgsevneernæringsstatusOriginal Researchdrikkemåltidpasientsikkerhetegenomsorglivskvalitetbusiness.industryscreeningrisikohealthGeneral Medicineopplevelse av sammenhengunderernæringmedicine.diseasePeer reviewhelseMalnutritionnutritionernæringskartleggingSelf carebusinessSense of coherenceernæring
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Lived experiences of self-care among older, home-dwelling individuals identified to be at risk of undernutrition

2012

Solveig T Tomstad,1,2 Ulrika Söderhamn,2 Geir Arild Espnes,3 Olle Söderhamn21Department of Social Work and Health Science, Norwegian University of Science and Technology, Trondheim, Norway; 2Centre for Caring Research – Southern Norway, University of Agder, Grimstad, Norway; 3Research Centre for Health Promotion and Resources HiST-NTNU, Department of Social Work and Health Science, Norwegian University of Science and Technology, Trondheim, NorwayIntroduction: In a society where most older people live in their own homes, it may be expected of older individuals to exercise their potential to take care of themselves in daily life. Nutrition is a central aspect of se…

Gerontologyhealth promotionHome dwellinghjemmeboendeNorgefenomenologiqualitative interviewsforebyggingVDP::Medical disciplines: 700::Health sciences: 800::Nursing science: 808mathelsefremmingeldreegenomsorgsevneMedicineernæringsstatusLicenseGeneral NursingintervjuOriginal Researchdrikkemåltidpasientsikkerhetegenomsorglivskvalitetbusiness.industryJournal of Multidisciplinary HealthcarerisikoVDP::Medical disciplines: 700::Clinical medical disciplines: 750::Geriatrics: 778General Medicineunderernæringmedicine.diseasehelsePeer reviewMalnutritionagedHealth promotionLicenseephenomenologybusinessAttributionDoveernæringJournal of Multidisciplinary Healthcare
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Psychometric testing of the Norwegian version of the Nutritional Form For the Elderly among older home-dwelling people

2012

Ulrika Söderhamn, Bjørg Dale, Kari Sundsli, Solveig T Tomstad, Olle SöderhamnCenter for Caring Research, Southern Norway, Faculty of Health and Sport Sciences, University of Agder, Grimstad, NorwayBackground: Nutritional screening instruments need to be evaluated in terms of reliability and validity and being able to demonstrate sensitivity and specificity for use in clinical practice and research. The aims of this study were to test the reliability and validity of the Norwegian version of the Nutritional Form For the Elderly (NUFFE-NO) in a sample of older home-dwelling people, and to use the short form of the Mini Nutritional Assessment (MNA-SF) as a standard.…

GerontologyvalidityAlternative medicinespecificitytverrsnittkartleggingMultidisciplinary approachHealth careegenomsorgsevneernæringsstatusGeneral NursingOriginal ResearchdrikkemåltidegenomsorgJournal of Multidisciplinary HealthcareVDP::Medical disciplines: 700::Clinical medical disciplines: 750::Geriatrics: 778General MedicineunderernæringtestingMNANUFFE-NOlanguagePredictive validitymedicine.medical_specialtyHome dwellinghjemmeboendeNorwegianNorgeNutritional Form For the ElderlyforebyggingVDP::Medical disciplines: 700::Health sciences: 800::Nursing science: 808mattverrsnittstudieeldremedicinePsychometric testingreliabilitypasientsikkerhetMini Nutritional Assessmentlivskvalitetbusiness.industryscreeningrisikosensitivitylanguage.human_languagehelseernæringskartleggingnutritional screening instrumentvalideringbusinessDoveernæring
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