Search results for "nucleus"

showing 10 items of 1803 documents

Experimental techniques for testing the sensitivity of bladder tumours to antineoplastic drugs

1973

A number of laboratory tests can be employed to examine the sensitivity of human bladder tumour cells to various chemotherapeutic agents.-Their principles and methods, and some preliminary results, are described with special reference to certain in vitro and in vivo cytotoxicity tests and to heterotransplantation in the hamster. Satisfactory agreement has sometimes been observed between experimental results and clinical responses, but our experience is still very limited.-The employment of several such tests would probably lead to a greater degree of reliability in the laboratory assessment of the sensitivity of bladder tumours to cytotoxic drugs.

Oncologymedicine.medical_specialtyPathologyAdministration TopicalUrologyTransplantation HeterologousHuman bladderDrug ResistanceHamsterAntineoplastic AgentsBLADDER PAPILLOMAThiophenesFluorescenceCricetinaeInternal medicinemedicineAnimalsHumansGlycosidesMelphalanIn vivo cytotoxicityPodophyllotoxinCell NucleusCarcinoma Transitional Cellbusiness.industryDaunorubicinDemecolcineDNA NeoplasmCytotoxicity Tests ImmunologicMicroscopy FluorescenceUrinary Bladder NeoplasmsDoxorubicinProtein BiosynthesisAntineoplastic DrugsOxidoreductasesbusinessNeoplasm TransplantationThiotepaUrological Research
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Functional Connectivity of Nucleus Accumbens and Medial Prefrontal Cortex With Other Brain Regions During Early-Abstinence Is Associated With Alcohol…

2021

Background: Alcohol dependence (AD) is a chronic recurrent brain disease that causes a heavy disease burden worldwide, partly due to high relapse rates after detoxification. Verified biomarkers are not available for AD and its relapse, although the nucleus accumbens (NAc) and medial prefrontal cortex (mPFC) may play important roles in the mechanism of addiction. This study investigated AD- and relapse-associated functional connectivity (FC) of the NAc and mPFC with other brain regions during early abstinence.Methods: Sixty-eight hospitalized early-abstinence AD male patients and 68 age- and education-matched healthy controls (HCs) underwent resting-functional magnetic resonance imaging (r-f…

Oncologymedicine.medical_specialtyrest-functional magnetic resonance imaginglcsh:RC435-571media_common.quotation_subjectalcohol dependencepredictorNucleus accumbensbehavioral disciplines and activitiesGyrusInternal medicinelcsh:PsychiatrymedicinePrefrontal cortexmedia_commonOriginal ResearchPsychiatryrelapsemedicine.diagnostic_testbusiness.industryAddictionAlcohol dependencefunctional connectivityrelapse severityMagnetic resonance imagingAbstinencePsychiatry and Mental healthmedicine.anatomical_structurenervous systemFunctional magnetic resonance imagingbusinesspsychological phenomena and processesFrontiers in Psychiatry
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Multiple activation pathways of benzene leading to products with varying genotoxic characteristics.

1989

Abstract Benzene and 13 potential metabolites were investigated for genotoxicity in Salmonella typhimurium and V79 Chinese hamster cells. In the presence of NADPH-fortified hepatic postmitochondrial fraction (S9 mix), benzene reverted his- S. typhimurium strains. The effect was strongest in strain TA1535. Among the potential metabolites, only the trans-1,2-dihydrodiol, in the presence of S9 mix, and the diol epoxides, in the presence and absence of S9 mix, proved mutagenic in this strain. The anti-diol epoxide was more potent than the syn-diastereomer. Both enantiomers of the anti-diastereomer showed similar activities. S9 mix did not appreciably affect the mutagenicity of the anti-diol epo…

Oxidoreductases Acting on CH-CH Group DonorsHealth Toxicology and MutagenesisEpoxideSister chromatid exchangeGene mutationIn Vitro Techniquesmedicine.disease_causechemistry.chemical_compoundmedicinepolycyclic compoundsAnimalsBiotransformationCatecholHydroquinoneMutagenicity TestsPublic Health Environmental and Occupational HealthBenzeneQuinoneAlcohol OxidoreductaseschemistryBiochemistryMicronucleus testOxidoreductasesGenotoxicityResearch ArticleMutagensEnvironmental Health Perspectives
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"Table 2" of "Transverse momentum of J / psi produced in p Cu, p U, O-16 Cu, O-16 U and S-32 U collisions at 200-GeV per nucleon."

1991

CONTINUUM MUONS ORIGINATE MAINLY FROM VECTOR MESON DECAYS, SEMI-LEPTONIC DECAYS OF D DBAR PAIRS AND FROM DRELL-YAN MECHANISM.

P CU --> MU- MU+ XS32 U --> MU- MU+ XO16 U --> MU- MU+ XDi-Muon ProductionP NUCLEUS --> MU+ MU- XNuclear TheoryHigh Energy Physics::PhenomenologyDeep Inelastic ScatteringMathematics::General TopologyMuon productionJ/PsiInclusiveSingle Differential Cross SectionHigh Energy Physics::ExperimentDSIG/DPTPsiCharged CurrentO16 CU --> MU- MU+ XNuclear ExperimentTransverse Momentum DependenceNUCLEUS NUCLEUS --> MU+ MU- XP U --> MU- MU+ X
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"Table 3" of "Production of D, D* and D(s) Mesons in 200-GeV/c pi-, K- and p Si Interactions"

1987

No description provided.

P NUCLEUS --> DBAR XInclusiveP NUCLEUS --> D XIntegrated Cross SectionCross SectionSIG
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"Table 14" of "Large-angle production of charged pions by 3 GeV/c - 12.9 GeV/c protons on beryllium, aluminium and lead targets"

2007

Double-differential cross section for PI- production from BE in the LAB system for PI- polar angle from 1.15 to 1.35 radians.

P NUCLEUS --> PI- XInclusiveD2SIG/DP/DTHETAP BE --> PI- XDouble Differential Cross SectionAngular Dependence
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"Table 15" of "Large-angle production of charged pions by 3 GeV/c - 12.9 GeV/c protons on beryllium, aluminium and lead targets"

2007

Double-differential cross section for PI- production from BE in the LAB system for PI- polar angle from 1.35 to 1.55 radians.

P NUCLEUS --> PI- XInclusiveD2SIG/DP/DTHETAP BE --> PI- XDouble Differential Cross SectionAngular Dependence
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"Table 18" of "Large-angle production of charged pions by 3 GeV/c - 12.9 GeV/c protons on beryllium, aluminium and lead targets"

2007

Double-differential cross section for PI- production from BE in the LAB system for PI- polar angle from 1.95 to 2.15 radians.

P NUCLEUS --> PI- XInclusiveD2SIG/DP/DTHETAP BE --> PI- XDouble Differential Cross SectionAngular Dependence
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"Table 13" of "Large-angle production of charged pions by 3 GeV/c - 12.9 GeV/c protons on beryllium, aluminium and lead targets"

2007

Double-differential cross section for PI- production from BE in the LAB system for PI- polar angle from 0.95 to 1.15 radians.

P NUCLEUS --> PI- XInclusiveD2SIG/DP/DTHETAP BE --> PI- XDouble Differential Cross SectionAngular Dependence
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"Table 12" of "Large-angle production of charged pions by 3 GeV/c - 12.9 GeV/c protons on beryllium, aluminium and lead targets"

2007

Double-differential cross section for PI- production from BE in the LAB system for PI- polar angle from 0.75 to 0.95 radians.

P NUCLEUS --> PI- XInclusiveD2SIG/DP/DTHETAP BE --> PI- XDouble Differential Cross SectionAngular Dependence
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