Search results for "nucleus"
showing 10 items of 1803 documents
Protoparvovirus Knocking at the Nuclear Door
2017
Protoparvoviruses target the nucleus due to their dependence on the cellular reproduction machinery during the replication and expression of their single-stranded DNA genome. In recent years, our understanding of the multistep process of the capsid nuclear import has improved, and led to the discovery of unique viral nuclear entry strategies. Preceded by endosomal transport, endosomal escape and microtubule-mediated movement to the vicinity of the nuclear envelope, the protoparvoviruses interact with the nuclear pore complexes. The capsids are transported actively across the nuclear pore complexes using nuclear import receptors. The nuclear import is sometimes accompanied by structural chan…
2021
Parvoviruses are small single-stranded (ss) DNA viruses, which replicate in the nucleoplasm and affect both the structure and function of the nucleus. The nuclear stage of the parvovirus life cycle starts at the nuclear entry of incoming capsids and culminates in the successful passage of progeny capsids out of the nucleus. In this review, we will present past, current, and future microscopy and biochemical techniques and demonstrate their potential in revealing the dynamics and molecular interactions in the intranuclear processes of parvovirus infection. In particular, a number of advanced techniques will be presented for the detection of infection-induced changes, such as DNA modification…
$^{78}$Ni revealed as a doubly magic stronghold against nuclear deformation
2019
Nuclear magic numbers, which emerge from the strong nuclear force based on quantum chromodynamics, correspond to fully occupied energy shells of protons, or neutrons inside atomic nuclei. Doubly magic nuclei, with magic numbers for both protons and neutrons, are spherical and extremely rare across the nuclear landscape. While the sequence of magic numbers is well established for stable nuclei, evidence reveals modifications for nuclei with a large proton-to-neutron asymmetry. Here, we provide the first spectroscopic study of the doubly magic nucleus $^{78}$Ni, fourteen neutrons beyond the last stable nickel isotope. We provide direct evidence for its doubly magic nature, which is also predi…
Non-symmetrized Hyperspherical Harmonics Method for Non-equal Mass Three-Body Systems
2018
The non-symmetrized hyperspherical harmonics method for a three-body system, composed by two particles having equal masses, but different from the mass of the third particle, is reviewed and applied to the $^3$H, $^3$He nuclei and $^3_{\Lambda}$H hyper-nucleus, seen respectively as $nnp$, $ppn$ and $NN\Lambda$ three-body systems. The convergence of the method is first tested in order to estimate its accuracy. Then, the difference of binding energy between $^3$H and $^3$He due to the difference of the proton and the neutron masses is studied using several central spin-independent and spin-dependent potentials. Finally, the $^3_{\Lambda}$H hypernucleus binding energy is calculated using diffe…
Understanding the Significance of the Hypothalamic Nature of the Subthalamic Nucleus
2021
AbstractThe subthalamic nucleus (STN) is an essential component of the basal ganglia and has long been considered to be a part of the ventral thalamus. However, recent neurodevelopmental data indicated that this nucleus is of hypothalamic origin which is now commonly acknowledged. In this work, we aimed to verify whether the inclusion of the STN in the hypothalamus could influence the way we understand and conduct research on the organization of the whole ventral and posterior diencephalon. Developmental and neurochemical data indicate that the STN is part of a larger glutamatergic posterior hypothalamic region that includes the premammillary and mammillary nuclei. The main anatomic charact…
"Table 3" of "Measurement of very forward energy and particle production at midrapidity in pp and p-Pb collisions at the LHC"
2022
Pb-remnant side ZN signal normalized to MB value vs. ZN centrality percentile in p-Pb collisions at 5.02 TeV
"Table 5" of "Measurement of very forward energy and particle production at midrapidity in pp and p-Pb collisions at the LHC"
2022
p-remnant side ZN signal normalized to MB value vs. ZN centrality percentile in p-Pb collisions at 5.02 TeV
"Table 9" of "Measurement of very forward energy and particle production at midrapidity in pp and p-Pb collisions at the LHC"
2022
p-remnant side ZN signal normalized to MB value vs. average Ncoll in p-Pb collisions at 5.02 TeV
"Table 7" of "Measurement of very forward energy and particle production at midrapidity in pp and p-Pb collisions at the LHC"
2022
Pb-remnant side ZN signal normalized to MB value vs. average Ncoll in p-Pb collisions at 5.02 TeV
Evidence of oblate-prolate shape coexistence in the strongly-deformed nucleus 119Cs
2021
International audience; Prolate-oblate shape coexistence close to the ground state in the strongly-deformed proton-rich A≈120 nuclei is reported for the first time. One of the four reported bands in 119Cs, built on a 11/2− state at 670 keV, consists of nearly degenerate signature partners, and has properties which unequivocally indicate the strongly-coupled πh11/2[505]11/2− configuration associated with oblate shape. Together with the decoupled πh11/2[541]3/2− band built on the 11/2− prolate state at 110 keV, for which a half-life of T1/2=55(5)μs has been measured, the new bands bring evidence of shape coexistence at low spin in the proton-rich strongly deformed A≈120 nuclei, a phenomenon p…