Search results for "outer"

showing 10 items of 252 documents

Susceptibility of Pseudomonas aeruginosa isolates to ceftazidime is unrelated to the expression of the outer membrane protein OprC.

1997

Previously, it has been postulated that the porin OprC facilitates the diffusion of ceftazidime through the outer membrane of Pseudomonas aeruginosa. To further investigate this claim, the outer membrane protein (OMP) profiles of 22 ceftazidime-susceptible clinical isolates were analyzed. No correlation was found between MIC values and the level of expression of OprC. Further, OprC was either undetectable or expressed in reduced amounts in 12 isolates. In contrast, OprF and OprE were present in all isolates studied. This study suggests that OprC is dispensable for the permeation of ceftazidime through the outer membrane of P. aeruginosa.

CeftazidimePorinsmedicine.disease_causePorinaCeftazidimeMicrobiologyBacterial ProteinsDrug DiscoverymedicineHumansPharmacology (medical)Antibacterial agentPharmacologybiologyPseudomonas aeruginosaGeneral Medicinebiology.organism_classificationCephalosporinsImipenemInfectious DiseasesOncologyMembrane proteinSpainPorinPseudomonas aeruginosaThienamycinsBacterial outer membranePseudomonadaceaemedicine.drugBacterial Outer Membrane ProteinsChemotherapy
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The translocation of signaling molecules in dark adapting mammalian rod photoreceptor cells is dependent on the cytoskeleton.

2008

In vertebrate rod photoreceptor cells, arrestin and the visual G-protein transducin move between the inner segment and outer segment in response to changes in light. This stimulus dependent translocation of signalling molecules is assumed to participate in long term light adaptation of photoreceptors. So far the cellular basis for the transport mechanisms underlying these intracellular movements remains largely elusive. Here we investigated the dependency of these movements on actin filaments and the microtubule cytoskeleton of photoreceptor cells. Co-cultures of mouse retina and retinal pigment epithelium were incubated with drugs stabilizing and destabilizing the cytoskeleton. The actin a…

Cell signalingCytochalasin Dgenetic structuresLightPaclitaxelPhalloidineDark AdaptationBiologyHeterocyclic Compounds 4 or More RingsMicrotubulesRetinaMiceStructural BiologyMicrotubuleRetinal Rod Photoreceptor CellsCytoskeletal drugsThiabendazolemedicineArrestinAnimalsTransducinCytoskeletonMicroscopy ImmunoelectronActinCytoskeletonVision OcularMice KnockoutRetinal pigment epitheliumArrestinHomozygoteCell BiologyDarknessRod Cell Outer Segmenteye diseasesActinsCell biologyMice Inbred C57BLActin CytoskeletonProtein Transportmedicine.anatomical_structureMicroscopy Fluorescencesense organsTransducinCell Migration AssaysSignal TransductionCell motility and the cytoskeleton
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BIOACTIVE GLASS CERAMIC

1983

The practicability of the bioactive glass ceramic Cernvitnl® in ear surgery was tested in animals. The histological findings are presented. Over the last 3 years implants of bioactive glass ceramic were used in humans. Prostheses for the total or partial reconstruction of the ossicular chain and the reconstruction of the bony wall of the outer ear canal were fashioned. We have conducted about 300 tympanoplasties and 60 total or partial reconstructions of the bony wall of the outer ear canal. The otoscopic and functional results were satisfactory.

CeramicsTympanic Membranemedicine.medical_treatmentHearing Loss ConductiveDentistryBiocompatible Materialslaw.inventionTympanoplastyOsteogenesislawotorhinolaryngologic diseasesmedicineOuter earAnimalsHumansCeramicEar OssiclesOssicular chainbusiness.industryProstheses and ImplantsTympanoplastymedicine.anatomical_structureOtorhinolaryngologyBioactive glassvisual_artvisual_art.visual_art_mediumGlassRabbitssense organsbusinessEar CanalThe Laryngoscope
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Tissue reactions to glass ceramics in the middle ear

1981

The bioactive glass ceramic "Ceravital" was used to fashion prostheses for the replacement of various ossicles in the middle ear. They were tested in 70 rabbit ears, where they were accepted in osseous areas without formation of surrounding fibrous tissue. Histological examinations regularly showed an osseous bond with the surrounding bony tissue. Mucous membrane covered these ossicular chain prostheses and showed no evidence of inflammatory reactions. Glass ceramic implants were also used to reconstruct the ossicular chain and the posterior wall of the outer ear canal in 100 patients. The functional results were satisfactory in all cases.

Ceramicsmedicine.medical_treatmentEar MiddleDentistrylaw.inventionTympanoplastylawotorhinolaryngologic diseasesmedicineOuter earAnimalsCeramicOssicular chainOssiclesbusiness.industryMucous membraneProstheses and ImplantsAnatomyTympanoplastymedicine.anatomical_structureOtorhinolaryngologyBioactive glassvisual_artvisual_art.visual_art_mediumMiddle earRabbitssense organsbusinessClinical Otolaryngology
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Neurons of the medial cortex outer plexiform layer of the lizard Podarcis hispanica: Golgi and immunocytochemical studies.

1994

The study of Golgi-impregnated lizard brains has revealed a scarce but heterogeneous neuronal population in the outer plexiform layer of the medial cortex. Some of the neuronal types detected here resemble the neurons of the dentate molecular layer of the mammalian hippocampus. According to their morphology, five intrinsic neuronal types have been clearly identified: short axon aspinous bipolar neuron (type 1, or sarmentous neuron), short axon aspinous juxtasomatic neuron (type 2, or coral neuron), short axon sparsely spinous multipolar neuron (type 3, or stellate neuron), short axon sparsely spinous juxtasomatic multipolar neuron (type 4, or deep stellate neuron, and sparsely spinous juxta…

Cerebral CortexMaleNeuronsMedial cortexGeneral NeuroscienceHippocampusOuter plexiform layerLizardsBiologyImmunohistochemistryAxonsMultipolar neuronmedicine.anatomical_structureParvalbuminsnervous systemBipolar neuronmedicineAnimalsFemaleNeuronAxonUnipolar neuronNeurosciencegamma-Aminobutyric AcidThe Journal of comparative neurology
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Long-spined polymorphic neurons of the medial cortex of lizards: a Golgi, Timm, and electron-microscopic study.

1988

The morphology, ultrastructure, and principal synaptic input of longspined neurons located in the inner plexiform layer of the medial cortex in three related species of lizards is described. Golgi impregnations have been used to define the external morphology of these neurons and their axonal trajectories. Their most striking characteristic is the presence of very long spines or “microdendrites” especially abundant on the distal dendritic segments. Axons have ascendent trajectories, pass through the cell layer, and ramify in the outer plexiform layer. Combined Golgi-electron microscopy as well as standard electron microscopy permitted the definition of the ultrastructure of these neurons. T…

Cerebral CortexNeuronsDendritic spineMedial cortexHistocytochemistryGeneral NeuroscienceOuter plexiform layerDendriteLizardsAnatomyDendritesBiologyInner plexiform layerMicroscopy ElectronZincmedicine.anatomical_structurenervous systemCerebral cortexMetalsmedicineBiophysicsUltrastructureAnimalsFascia dentataThe Journal of comparative neurology
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On the automorphism group of the integral group ring of Sk wr Sn

1992

Abstract Let G = SkwrSn be the wreath product of two symmetric groups Sk and Sn. We prove that every normalized automorphism θ of the integral group ring Z G can be written in the form θ = γ ° τu, where γ is an automorphism of G and τu denotes the inner automorphism induced by a unit u in Q G.

CombinatoricsAlgebra and Number TheoryInner automorphismHolomorphSymmetric groupMathematical analysisOuter automorphism groupAlternating groupAutomorphismUnit (ring theory)Group ringMathematicsJournal of Pure and Applied Algebra
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Automorphisms of the integral group ring of the hyperoctahedral group

1990

The purpose of this paper is to verify a conjecture of Zassenhaus [3] for hyperoctahedral groups by proving that every normalized automorphism () of ZG can be written in the form () = Tu 0 I where I is an automorphism of ZG obtained by extending an automorphism of G linearly to ZG and u is a unit of (JJG. A similar result was proved for symmetric groups by Peterson in [2]; the reader should consult [3] or the survey [4] for other results of this kind. 1989

CombinatoricsAlgebra and Number TheoryMatrix groupSymmetric groupAutomorphisms of the symmetric and alternating groupsOuter automorphism groupAlternating groupHyperoctahedral groupTopologyAutomorphismMathematicsGroup ringCommunications in Algebra
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Hausdorff measures and dimension

1995

CombinatoricsHausdorff distancePacking dimensionHausdorff dimensionMinkowski–Bouligand dimensionDimension functionHausdorff measureOuter measureEffective dimensionMathematics
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Characterization of chain geometries of finite dimension by their automorphism group

1990

A large class of chain geometries of finite dimension is characterized as strong chain spaces possessing a distinguished group of automorphisms fixing two distant points.

CombinatoricsInner automorphismChain (algebraic topology)HolomorphSymmetric groupSO(8)Alternating groupOuter automorphism groupGeometry and TopologyAutomorphismMathematicsGeometriae Dedicata
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