Search results for "pene"

showing 10 items of 1436 documents

Antifungal activity of the carrot seed oil and its major sesquiterpene compounds.

2005

Carrot seed oil is the source of the carotane sesquiterpenes carotol, daucol and β-caryophyllene. These sesquiterpenic allelochemicals were evaluated against Alternaria alternata isolated from the surface of carrot seeds cultivar Perfekcja, a variety widely distributed in horticultural practise in Poland. Alternaria alternata is one of the most popular phytotoxic fungi infesting the carrot plant. The strongest antifungal activity was observed for the main constituent of carrot seed oil, carotol, which inhibited the radial growth of fungi by 65% at the following concentration.

AntifungalAntifungal Agentsmedicine.drug_classcarrot seeds oilSesquiterpeneAlternaria alternataGeneral Biochemistry Genetics and Molecular BiologyCarotolchemistry.chemical_compoundBotanymedicinePlant OilsCultivarAllelopathybiologyantifungal activityAlternariaCarrot seed oilbiology.organism_classificationDaucus carotaRadial growthchemistrycarotolSeedsdaucolSesquiterpenesZeitschrift fur Naturforschung. C, Journal of biosciences
researchProduct

Bioactivity of essential oils in phytopathogenic and post-harvest fungi control

2017

[EN] Commercial thyme and lavender essential oils were analysed by GC/MS. Sixty-six compounds accounting for 98.6¿99.6% of total essential oil were identified. Thymol (52.14 ± 0.21%), followed by pcymene (32.24 ± 0.16%), carvacrol (3.71 ± 0.01%) and ¿-terpinene (3.34 ± 0.02%), were the main compounds in thyme essential oil, while large amounts of oxygenated monoterpenes linalool acetate (37.07 ± 0.24%) and linalool (30.16 ± 0.06%) were found in lavender one. In vitro antifungal activity of the essential oils was evaluated at 200 and 300 ¿g/mL against 10 phytopathogenic and post-harvest fungi, which significantly affect agriculture. Micelial growth inhibition was calculated for each tested f…

AntifungalLavendermedicine.drug_classAcyclic MonoterpenesBOTANICAPlant ScienceFungusCyclohexane MonoterpenesMicrobial Sensitivity Tests01 natural sciencesBiochemistryGas Chromatography-Mass SpectrometryAnalytical Chemistrylaw.inventionThymus Plantchemistry.chemical_compoundLinaloollawLavenderBotanymedicineOils VolatilePlant OilsCarvacrolFood scienceAntifungal activityThymolEssential oilBIOLOGIA VEGETALbiology010405 organic chemistryOrganic ChemistryFungiThymebiology.organism_classificationThymol0104 chemical sciencesFungicides Industrial010404 medicinal & biomolecular chemistryLavandulachemistryEssential oilsMonoterpenesCymenesGrowth inhibition
researchProduct

Studies on puupehenone-metabolites of a Dysidea sp.: structure and biological activity

2007

[EN] Puupchenone (1) and a series of its congeners (2-6) have been isolated from a Dysidea sponge. The unprecedented 20-acetoxyhater-unnadienone (2) exhibiting a five-membered contracted ring, has been characterized. In addition, stereochemical assignment of two previously reported acetone adducts of puupehenone (5 and 6) has been made. Finally, the inhibition of mitochondrial respiratory chain as well as antibacterial and antifungal activities of all compounds has been evaluated. (c) 2006 Elsevier Ltd. All rights reserved.

AntifungalMitochondrial respiratory chainbiologyMarine metabolitesmedicine.drug_classStereochemistryChemistryPuupehenoneOrganic ChemistryBiological activitySponges; Marine metabolites; Sesquiterpene-quinones; Antifungal; Antibacterial; Mitochondrial respiratory chain.biology.organism_classificationAntifungalBiochemistryAdductAntibacterialSpongeMitochondrial respiratory chainSpongesDrug DiscoverymedicineSesquiterpene-quinonesBIOQUIMICA Y BIOLOGIA MOLECULARTetrahedron
researchProduct

Bioactive saponins from plants: An update

2000

Plant saponins are a group of naturally occuring triterpene or steroid glycosides which include a large number of biologically and pharmacologically active compounds. Saponins have been shown in both in vitroand in vivoexperimental test systems during the last decade to possess a broad spectrum of biological and pharmacological activities. This review will summarize some of the recent advances concerning cancer-related activity, immunostimulating, immunoadjuvant, antihepatotoxic, antiphlogistic, antiallergic, molluscicidal, hemolytic, antifungal, antiviral, and hypoglycemic activities. In addition, the effects on the cardiovascular system and the central nervous system will be discussed tog…

Antifungalchemistry.chemical_classificationBroad spectrumchemistryTriterpenemedicine.drug_classmedicine.medical_treatmentmedicineGlycosidePharmacologyBiologyImmunoadjuvantSteroid
researchProduct

Selective oxidation of propane over alkali-doped Mo-V-Sb-O catalysts

2009

[EN] Alkali metal-doped MoVSbO catalysts have been prepared by impregnation of a MoVSbO-mixed oxide (prepared previously by a hydrothermal synthesis) and finally activated at 500 or 600 degrees C in N-2. The catalysts have been characterized and tested for the selective oxidation of propane and propylene. Alkali-doped catalysts improved in general the catalytic performance of MoVSbO, resulting more selective to acrylic acid and less selective to acetic acid than the corresponding alkali-free MoVSbO catalysts. However, the specific behaviour strongly depends on both the alkali metal added and/or the final activation temperature. At isoconversion conditions, catalysts activated at 600 degrees…

AntimonyCarboxylic acidIndustrial catalystsInorganic chemistryLithiumHeterogeneous catalysisAcetic acidCatalysisCatalysisPropeneAcrylic acidchemistry.chemical_compoundAcetic acidTransition metalAcrylic acidchemistry.chemical_classificationMolybdenumSodiumVanadiumGeneral ChemistryCaesiumchemistryPotassiumMetal oxidesPropane oxidation
researchProduct

Effect of Stevia rebaudiana addition on bioaccessibility of bioactive compounds and antioxidant activity of beverages based on exotic fruits mixed wi…

2015

In order to determine the impact of Stevia rebaudiana (SR) addition on bioactive compounds bioaccessibility of a new developed functional beverage based on exotic fruits (mango juice, papaya juice and acai) mixed with orange juice and oat, an in vitro gastrointestinal digestion was performed. Ascorbic acid, total carotenoids, total phenolics, total anthocyanins, total antioxidant capacity and steviol glycosides were evaluated before and after a simulated gastrointestinal digestion. Salivary and gastric digestion had no substantial effect on any of the major phenolic compounds, ascorbic acid, total antioxidant capacity and steviol glycosides, whereas carotenoids and anthocyanins diminished s…

AntioxidantAvenamedicine.medical_treatmentSteviolAscorbic AcidAntioxidantsAnalytical ChemistryAnthocyaninsBeverageschemistry.chemical_compoundGlucosidesPhenolsmedicineHumansSteviaFood scienceCarotenoidOrange juicechemistry.chemical_classificationfood and beveragesGlycosideGeneral MedicineAscorbic acidCarotenoidsStevia rebaudianachemistryBiochemistryFruitDigestionDigestionDiterpenes KauraneFood ScienceFood chemistry
researchProduct

Synthesis and evaluation of diverse thio avarol derivatives as potential UVB photoprotective candidates.

2007

Semisynthesis of 13 new thio avarol derivatives (4-16) and in vitro evaluation on the photodamage response induced by UVB irradiation are described. Their ability to inhibit NF-kappaB activation and TNF-alpha generation in HaCaT cells as well as their antioxidant capacity in human neutrophils has also been studied. Among them we have identified two monophenyl thio avarol derivatives (4-5) lacking cytotoxicity which can be considered promising UVB photoprotective agents through the potent inhibition of NF-kappaB activation with a mild antioxidant pharmacological profile.

AntioxidantMagnetic Resonance SpectroscopyNeutrophilsPhotochemistryUltraviolet Raysmedicine.medical_treatmentChemistry PharmaceuticalClinical BiochemistryMolecular ConformationPharmaceutical ScienceThio-BiochemistryChemical synthesisAntioxidantsCell Line TumorDrug DiscoverymedicineHumansCytotoxicityMolecular Biologyintegumentary systemChemistryTumor Necrosis Factor-alphaOrganic ChemistryNF-kappa BSemisynthesisIn vitroHaCaTmedicine.anatomical_structureBiochemistryModels ChemicalDrug DesignMolecular MedicineKeratinocyteReactive Oxygen SpeciesSesquiterpenesBioorganicmedicinal chemistry letters
researchProduct

Stability of carotenoid extracts of gấc (Momordica cochinchinensis) towards cooxidation — Protective effect of lycopene on β-carotene

2011

International audience; Momordica cochinchinensis, so-called gấc in Vietnam, is considered as a fruit with high nutritional potential. Its antioxidant property, due to a high concentration of carotenes (β-carotene and lycopene), is particularly estimated. In this study, we have investigated the degradation of carotene extracts obtained from gấc aril. These extracts were dispersed in the aqueous phase in Tween 80 micelles or were encapsulated into polylactic acid (PLA) particles. In both cases, carotenes were far less degraded than synthetic β-carotene. However, the degradation of lycopene was still rapid (around 1 mM lycopene degraded per hour), whereas β-carotene was almost not bleached. M…

AntioxidantMomordica cochinchinensismedicine.medical_treatmentIononeMicellePolylactic acid03 medical and health scienceschemistry.chemical_compoundLycopene0404 agricultural biotechnologyPolylactic acidGấcOxidationCarotene cleavage productsmedicineOrganic chemistry[SDV.BBM]Life Sciences [q-bio]/Biochemistry Molecular BiologyXanthine oxidaseCaroteneCarotenoid030304 developmental biologychemistry.chemical_classification0303 health sciencesbiologyCarotene04 agricultural and veterinary sciencesbiology.organism_classification040401 food scienceLycopenechemistryEncapsulationAntioxidantIononeFood ScienceFood Research International
researchProduct

Coffee components and cardiovascular risk: beneficial and detrimental effects

2014

Coffee consists of several biological active compounds, such as caffeine, diterpenes, chlorogenic acids, and melanoidins, which may affect human health. The intake of each compound depends on the variety of coffee species, roasting degree, type of brewing method and serving size. The bioavailability and the distribution of each compound and its metabolites also contribute to coffee mechanisms of action. The health benefits of coffee consumption regarding cardiovascular system and metabolism mostly depend on its antioxidant compounds. In contrast, diterpenes and caffeine may produce harmful effects by raising lipid fraction and affecting endothelial function, respectively. Studying the mecha…

AntioxidantSettore MED/09 - Medicina InternaPolymersmedicine.medical_treatmentLipid fractionCoffee consumptionBiologyHealth benefitsCardiovascular SystemCoffeeHuman healthchemistry.chemical_compoundAlkaloidsCaffeinemedicineHumansFood scienceSettore MED/49 - Scienze Tecniche Dietetiche ApplicatePlant ExtractsPolyphenolscoffee cardiovascular riskDiabetes Mellitus Type 2chemistryCardiovascular DiseasesChlorogenic AcidDiterpenesCaffeineFood Science
researchProduct

Kundmannia sicula (L.) DC: a rich source of germacrene D

2017

AbstractObjective: Kundmannia sicula is an herbaceous plant belonging to the family Apiaceae and is distributed in the Mediterranean coastal areas where it occurs in arid places. In this work, we have analysed the essential oil distilled from the aerial parts of K. sicula from Sicily (Italy) and its biological activity. Methods: GC-MS was used to analyze the chemical composition, whereas its antioxidant capacity and cytotoxicity on three human tumour cells (A375, MDA MB-231 and HCT 116) were evaluated by DPPH, ABTS, FRAP and MTT methods, respectively. Result: The essential oil resulted very rich of the sesquiterpene hydrocarbon germacrene D (81.2%). Moreover, the K. sicula oil displayed rel…

AntioxidantantioxidantDPPHmedicine.medical_treatmentBiologySesquiterpene01 natural sciencesessential oillaw.inventionchemistry.chemical_compoundlawKundmannia siculaBotanygermacrene DmedicineKundmannia siculaEssential oilABTS010405 organic chemistryChemistry (all)Biological activityGeneral ChemistryHerbaceous plant0104 chemical sciences010404 medicinal & biomolecular chemistrychemistrycytotoxicity
researchProduct