Search results for "peripheral"
showing 10 items of 1028 documents
Antithrombotische Therapie bei peripherer arterieller Verschlusskrankheit
2018
Was ist neu? Antithrombotische Therapie bei stabiler PAVK Die aktuellen deutschen und europäischen Leitlinien empfehlen bei Patienten mit einer peripheren arteriellen Verschlusskrankheit (PAVK) die Monotherapie mit einem Thrombozytenaggregationshemmer (ASS 100 mg oder Clopidogrel 75 mg).In der COMPASS (Cardiovascular OutcoMes for People using Anticoagulation StrategieS) -Studie wurde Patienten mit PAVK 2 × 2,5 mg Rivaroxaban zusätzlich zu ASS 100 mg gegeben. Dies führte zur signifikanten Reduktion kardiovaskulärer Ereignisse (MACE = Major Adverse Cardiovascular Events) wie kardiovaskulärer Tod, Myokardinfarkt und Schlaganfall. Ebenfalls signifikant reduziert wurden periphere Ereignisse (MAL…
Untersuchungen �ber die Beurteilung der Hautdurchblutung durch zentrale und periphere Temperaturmessungen
1974
Zur Diagnose und Therapie eines Schockgeschehens sind neben zentralen Parametern auch Angaben uber die periphere Durchblutung notwendig. Das am einfachsten zu erreichende Capillargebiet ist das der Haut. Die Hautdurchblutung stellt den wichtigsten Regulator fur den Warmestrom dar, so das ein Zusammenhang zwischen Hauttemperatur und Hautdurchblutung zu erwarten ist. Vergleiche der tatsachlichen Hautdurchblutung gemessen durch Δλ mit verschiedenen Hauttemperaturen, integrierte Hauttemperatur und Burton-Indices liesen keinen Zusammenhang erkennen. Jedoch ist die Korrelation mit der Rectum-Zehen-Temperaturdifferenz ΔT statistisch hoch signifikant. Sie kann ohne technischen Aufwand als orientier…
Akutes Nierenversagen auf dem Boden einer Hyperkalzämie und periphere Polyneuropathie – seltene Manifestationen einer Sarkoidose
2000
Hintergrund: Als Systemerkrankung kann die Sarkoidose alle Organsysteme befallen. Neben dem haufigen Befall von Lungen und thorakalen Lymphknoten kommen auch seltene Manifestationen wie Nierenversagen und eine Beteiligung des Nervensystems vor. Fallbericht: Ein 57-jahriger Patient wurde nach einem Urlaub im Suden mit Belastungsdyspnoe und akutem Nierenversagen bei Hyperkalzamie stationar aufgenommen. Der klinische Verdacht einer Sarkoidose als Grunderkrankung mit den ausergewohnlichen extrapulmonalen Manifestationen einer Kalziumnephropathie sowie einer sensiblen Polyneuropathie lies sich bestatigen. Schlusfolgerung: Dieser Fall zeigt, dase eine asymptomatische Sarkoidose durch vermehrte UV…
The role of exercise on peripheral nerve regeneration: from animal model to clinical application
2021
Peripheral nerve injury is a complex condition with a variety of signs and symptoms depending on the severity and nerves involved. Peripheral nerve damage may lead to sensory and motor functions deficits and even lifelong disability, causing important socioeconomic costs worldwide. Despite the increase in knowledge of the mechanisms of injury and regeneration, a full functional recovery is still unsatisfying in the majority of patients. It is well known that exercise promotes physical and psychological well-being, by ameliorating general health. In the last years, there has been a growing interest in evaluating the effects of exercise on the peripheral nervous system. Experimental works wit…
Macrophagic myofasciitis in a 3-month-old child
2015
Macrophagic myofasciitis (MMF) is a rare inflammatory myopathy which occurs after injection of aluminium-containing vaccines against hepatitis B virus (HBV), hepatitis A virus, and tetanus toxoid. Most of the cases reported are from France and are adult patients. We report a rare case of MMF in a 3-month-old male child of Indian origin. He was immunized for HBV at birth after which he developed generalized hypotonia, and central nervous system and peripheral nervous system manifestations at 1 month of age. Muscle biopsy showed typical features of MMF and aluminium could be detected in the muscle biopsy macrophages by ultrastructural examination and LAMMA technique. Our case is the youngest …
Ultrastructural localization of interferon-producing cells in the livers of patients with chronic hepatitis B
1991
Cells expressing alpha- and gamma-interferon were localized in the liver tissue of patients with chronic hepatitis B by means of light and electron microscopy using monoclonal antibodies. Interferon-positive cells were regularly seen in the infiltrating mononuclear cells, and the number showed a good correlation with the degree of the necroinflammatory activity of the disease. In chronic persistent hepatitis and in normal livers, they were infrequent or virtually absent. alpha-Interferon was shown to be positive in lymphocytes, polymorphonuclear leukocytes and fibroblasts, Kupffer cells and, weakly, in the cytoplasm of a few hepatocytes in cases of active hepatitis, whereas gamma-interferon…
Gamma-delta T-cell lymphomas.
2009
Peripheral T-cell lymphomas (TCLs) are uncommon neoplasms, accounting for about 12% of all lymphoid tumors worldwide. TCLs in which gammadelta T-cell receptors are expressed (gammadelta TCLs) are extremely aggressive and rare (<1% of lymphoid neoplasms). gammadelta TCLs originate from gammadelta T cells, a small subset of peripheral T cells with direct antigen recognition capability acting at the interface between innate and adaptive immunity. Two distinct gammadelta TCL entities are recognized: hepatosplenic T-cell lymphoma (HSTL) and primary cutaneous gammadelta T-cell lymphoma (PCGD-TCL). HSTL is a well-characterized extranodal lymphoma that has a disguised onset, secondary to intrasinus…
158 Timing of Fascia Iliaca Compartment Block (FICB) for Neck of Femur (NOF) fracture in the Accident and Emergency Department (AED) and the operatin…
2021
Background and Aims FICB is recommended for NOF fracture in the AED to improve analgesia1 and as an adjuvant to anaesthesia during surgery2. Surgical repair of the fracture should be performed on the day of, or the day after, admission3. We evaluated the provision of FICB in AED and its potential to cause local anaesthetic (LA) toxicity when followed by a further block at time of surgery. Methods All patients admitted to our institution with NOF fracture during October 2019 were retrospectively screened for FICBs. We recorded the time of: admission, FICB in AED, surgery, FICB in theatre and LA dose. Data was cross-referenced and validated against National Hip Fracture Database (NHFD) tables…
Nervenläsionen bei der Hüft-TEP-Implantation - Strategien zur Lähmungsprophylaxe
2003
Aim Nerve lesions are a serious complication of total hip arthroplasty. The incidence of lesions of large nerves exceeds those of luxation and septic loosening. An analysis of damage causes should lead to prophylactic strategies and improvement of operative technique. Patients are more aware of this complication and malpractice cases are increasing. Between 1977 and 2001 the medical association of North Rhine dealt with 126 cases of nerve lesions. Method All potential intraoperative causes for nerve damage are investigated. Results Incorrectly placed Hohmann retractors offer the largest damage potential. Electro surgery and self-cutting screws have a hazardous potential. Sharp injuries, ret…