Search results for "pero"

Julien : les années parisiennes

2009

This article intends to scrutinize in what ways Julian’s stay in Gaul as a Caesar were decisive in Julian’s political and military education, and whether a specific ruling style and manner may be detected in the Parisian years of Julian’s government. Relying on a critical analysis of the documentation (Julian himself, Mamertinus, Ammianus, Libanios), the author examines the military and civilian aspects of Julian’s training as an apparently inexperienced ruler but quick learner. She carries out a prosopographical study of the Caesar’s circle and the administrative staff which was then on duty, combining friendly and hostile persons. Gaul offered him a training ground and he became even the …

The Lupa Romana in the Roman provinces

2014

The she-wolf with the twins, Romulus and Remus, was identified as a symbol of Rome by both the Romans themselves and nations under the Roman rule. In this essay I will discuss the Lupa Romana in Roman provincial art. I will present various visual representations of the she-wolf both in the public use and in objects related to private life, and analyze the she-wolf’s symbolic meaning.The Lupa Romana was an iconic scene that was not used randomly in provincial art. It represented in the first place the idea of romanitas, being Roman. In some cases the use of the symbol could have been in consequence of instructions from Rome itself or from provincial authorities that depended on Rome, but in …

Archaeometric analysis of building ceramics and ‘dolia defossa’ from the Roman Imperial estate of Vagnari (Gravina in Puglia, Italy)

2021

Abstract This paper concerns the archaeometric analysis of ceramic finds dating to the Roman Imperial period, brought to light during the excavation campaigns conducted at Vagnari (Puglia) in south-east Italy. On the site of the central village (vicus) of this imperial estate, established by the Roman Emperor in the early 1st century CE, large dolia (wine vats) sunk into the floor of a winery of the 2nd century CE recently were brought to light. Other discoveries include kilns for the production of ceramic roof tiles and also kiln wasters such as misfired tiles. The purpose of the analytical approach was therefore twofold: 1) to establish the composition of local ceramic products and of raw…

Architettura e Costruzione nella Palermo tra le due Guerre. Tre edifici pubblici emblematici

2012

Attraverso l’esame di tre edifici pubblici realizzati a Palermo tra le due guerre il libro ricerca i prodromi della cultura architettonica moderna, diffusasi nel capoluogo siciliano sulla scia delle sperimentazioni formali e funzionali delle architetture di primo Novecento ispirate alle opere di Ernesto Basile e Damiani Almeyda. Il contributo innovativo apportato dalla nuove tecniche costruttive legate all’uso di nuovi materiali –quali il cemento armato- viene messo in evidenza attraverso lo studio delle vicende costruttive dei tre edifici che si pongono come esemplificative di un modus operandi oscillante tra “regola d’arte” e tecnologie “moderne”. L’analisi condotta sul corpo delle fabbri…

AR.TE.HA ARCHITETTURA TECNOLOGIA HABITAT La costruzione del progetto sostenibile

2011

Il volume approfondisce le tematiche e le problematiche dell’attività edilizia: dai saperi necessari per una corretta progettazione, all’ottimizzazione delle scelte costruttive, fino alla gestione esecutiva indirizzata alla qualità ed alla sostenibilità del progetto di architettura. La costruzione del progetto di architettura sostenibile presuppone la consapevolezza critica del dato materiale. Tale consapevolezza va intesa sia come conoscenza delle caratteristiche fisiche, espressive e prestazionali dei materiali, sia delle tecniche e dei sistemi costruttivi. Tanto la nuova costruzione, quanto il recupero edilizio implicano scelte responsabili supportate da una alta coscienza tecnologica vo…

Agathòn

2010

Biological effects of inorganic arsenic on primary cultures of rat astrocytes

2010

It is well established that inorganic arsenic induces neurotoxic effects and neurological defects in humans and laboratory animals. The cellular and molecular mechanisms of its actions, however, remain elusive. Herein we report the effects of arsenite (NaAsO2) on primary cultures of rat astrocytes. Cells underwent induction of heat shock protein 70 only at the highest doses of inorganic arsenic (30 and 60 microM), suggesting a high threshold to respond to stress. We also investigated arsenic genotoxicity with the comet assay. Interestingly, although cells treated with 10 microM arsenite for 24 h maintained >70% viability, with respect to untreated cells, high DNA damage was already observed…

Incipient genome erosion and metabolic streamlining for antibiotic production in a defensive symbiont

2021

Significance Genome reduction is commonly observed in bacteria of several phyla engaging in obligate nutritional symbioses with insects. In Actinobacteria, however, little is known about the process of genome evolution, despite their importance as prolific producers of antibiotics and their increasingly recognized role as defensive partners of insects and other organisms. Here, we show that “Streptomyces philanthi,” a defensive symbiont of digger wasps, has a G+C-enriched genome in the early stages of erosion, with inactivating mutations in a large proportion of genes, causing dependency on its hosts for certain nutrients, which was validated in axenic symbiont cultures. Additionally, overe…

The Peroxisomal 3-keto-acyl-CoA thiolase B Gene Expression Is under the Dual Control of PPARα and HNF4α in the Liver

2011

PPARα and HNF4α are nuclear receptors that control gene transcription by direct binding to specific nucleotide sequences. Using transgenic mice deficient for either PPARα or HNF4α, we show that the expression of the peroxisomal3-keto-acyl-CoA thiolase B(Thb) is under the dependence of these two transcription factors. Transactivation and gel shift experiments identified a novel PPAR response element within intron 3 of theThbgene, by which PPARα but not HNF4α transactivates. Intriguingly, we found that HNF4α enhanced PPARα/RXRα transactivation from TB PPRE3 in a DNA-binding independent manner. Coimmunoprecipitation assays supported the hypothesis that HNF4α was physically interacting with RXR…

Effect of ADH II Deficiency on the Intracellular Redox Homeostasis in Zymomonas mobilis

2011

Mutant strain of the facultatively anaerobic, ethanol-producing bacteriumZymomonas mobilis, deficient in the Fe-containing alcohol dehydrogenase isoenzyme (ADH II), showed impaired homeostasis of the intracellular NAD(P)H during transition from anaerobic to aerobic conditions, and also in steady-state continuous cultures at various oxygen supplies. At the same time, ADH II deficiency in aerobically grown cells was accompanied by a threefold increase of catalase activity and by about 50% increase of hydrogen peroxide excretion. It is concluded that ADH II under aerobic conditions functions to maintain intracellular redox homeostasis and to protect the cells from endogenous hydrogen peroxide.