Search results for "pig"
showing 10 items of 2235 documents
Antinociceptive effects of an extract, fraction and an isolated compound of the stem bark of Maytenus rigida
2012
The antinociceptive activity of the Maytenus rigida Mart. (Celastraceae) ethanol extract and its ethyl acetate fraction as well as of (-)-4'-methylepigallocatechin (1), a previously isolated compound, was demonstrated in vivo. ED50 for 1 in the writhing test was 14.14 mg/kg. The acetic acid-induced writhing was inhibited by 98.4, 84.4, and 58.3%, respectively, when mice were treated with the ethanol extract, ethyl acetate fraction, and 1. In the hot plate test, mice pretreated with 1 showed significantly increased reaction times (60-89%). Oral administration of 1 significantly inhibited first and second phases of the formalin-induced pain (50 and 26.5%, respectively), whereas indomethacin i…
LEUKASPIS: UN ELEMENTO INDIGENO NELLA RELIGIOSITA SICELIOTA?
1991
Attraverso l'esame di un'epigrafe proveniente dall'Heraion di Samo si analizza un brano del IV libro della Biblioteca Storica di Diodoro Siculo relativo al culto di eroi sicani nella Sicilia orientale, che secondo l'etnografia antica era invece abitata da Siculi. L'obiettivo è mostrare l'uso della strumento mitico da parte dei Greci a scopo di legittimazione politica.
The colours of Segesta. Searching for the traces of the lost pigments
2023
Many monuments and objects of the ancient civilizations were painted, but unfortunately the pigments are not still present and sometimes only small traces are evident. The analysis of the traces requires a multianalytical approach through the use of non-invasive techniques and only if necessary of a microsampling. Here, the study of the traces of colours found in some architectural elements and findings belonging to the Archeological Park of Segesta (Trapani, Italy) is reported. The traces are identified and characterised via several techniques such as Optical Microscopy, UV-Fluorescence Imaging, Fiber Optical Reflectance Spectroscopy (FORS), X-ray Fluorescence (XRF) and FT-IR Spectroscopy.…
Combinatorial proofs of two theorems of Lutz and Stull
2021
Recently, Lutz and Stull used methods from algorithmic information theory to prove two new Marstrand-type projection theorems, concerning subsets of Euclidean space which are not assumed to be Borel, or even analytic. One of the theorems states that if $K \subset \mathbb{R}^{n}$ is any set with equal Hausdorff and packing dimensions, then $$ \dim_{\mathrm{H}} π_{e}(K) = \min\{\dim_{\mathrm{H}} K,1\} $$ for almost every $e \in S^{n - 1}$. Here $π_{e}$ stands for orthogonal projection to $\mathrm{span}(e)$. The primary purpose of this paper is to present proofs for Lutz and Stull's projection theorems which do not refer to information theoretic concepts. Instead, they will rely on combinatori…
Production of neutron deficient rare isotope beams at IGISOL; on-line and off-line studies
2004
This article reports on recent on-line yield measurements employing the light-ion and heavy-ion reaction-based ion guide systems and new results on a-recoil ion transport properties in ion guides with and without electric fields. In addition, the presently used ion guide designs for fusion evaporation reactions are introduced. The present study investigated different schemes for ion extraction from the gas cell. The addition of an extra ring electrode between the traditional skimmer electrode and the exit hole led to transmission independent of the primary beam intensity as opposed to strong intensity dependence observed earlier with the plain skimmer only. Furthermore, the mass resolving p…
Transgenerational innovation capability in family firms
2020
PurposeBased on the theory of dynamic capabilities, the purpose of this study is to examine how generation influences the effect of innovation capability on family business performance. To achieve this purpose, a moderation model is tested using the generational level as the moderating variable.Design/methodology/approachThis study used a sample of 106 family businesses CEOs who were surveyed by mail using the Limesurvey 2.5 platform. The results obtained were analyzed using the second-generation partial least squares (PLS) structural equation model. The MICOM (Measurement Invariance of Composite Models) approach was used to analyze the moderating effect.FindingsThis research sheds lights o…
Application of ultrasound as clean technology for extraction of specialized metabolites from stinging nettle (Urtica dioica L.)
2022
Nettle is a highly valued medicinal plant that is still largely neglected, both in terms of nutrition and use for pharmacological purposes. Tinctures, i.e., alcoholic extracts, are becoming increasingly popular nettle products, mainly because they allow better availability of phytochemicals and their stability over a longer period of time. The production of alcoholic extracts is a chemically demanding process that is still usually carried out using conventional techniques, which have numerous drawbacks. The use of green technologies such as ultrasound-assisted extraction (UAE), which is characterized by high efficiency of phytochemical extraction, shorter treatment time, and a much lower en…
Histone post-translational modifications as potential therapeutic targets for pain management
2021
Effective pharmacological management of pain associated with tissue pathology is an unmet medical need. Transcriptional modifications in nociceptive pathways are pivotal for the development and the maintenance of pain associated with tissue damage. Accumulating evidence has shown the importance of the epigenetic control of transcription in nociceptive pathways via histone post-translational modifications (PTMs). Hence, histone PTMs could be targets for novel effective analgesics. Here, we discuss the current understanding of histone PTMs in the modulation of gene expression affecting nociception and pain phenotypes following tissue injury. We also provide a critical view of the translationa…
Regulation of cuticular hydrocarbon profile maturation by Drosophila tanning hormone, bursicon, and its interaction with desaturase activity
2016
International audience; Shortly after emergence the exoskeleton (cuticle) of adult insects is rapidly expanded, hardened (sclerotized), and pigmented (melanized). In parallel with this process, the oenocytes, which are large polyploid cells located below the abdominal epidermis, secrete onto the cuticle a cocktail of cuticular hydrocarbons (CHs) and waxes. These improve the waterproofing of the cuticle, and also provide important chemosensory and pheromonal cues linked with gender, age, and species differentiation. The hardening and pigmentation of the new cuticle are controlled by the neurohormone, bursicon, and its receptor, encoded by the DLGR2 receptor, rickets (rk); by contrast, little…
Polymorphisms in ABC transporter genes and concentrations of mercury in newborns - Evidence from two Mediterranean birth cohorts
2014
Background: The genetic background may influence methylmercury (MeHg) metabolism and neurotoxicity. ATP binding cassette (ABC) transporters actively transport various xenobiotics across biological membranes. Objective: To investigate the role of ABC polymorphisms as modifiers of prenatal exposure to MeHg. Methods: The study population consisted of participants (n = 1651) in two birth cohorts, one in Italy and Greece (PHIME) and the other in Spain (INMA). Women were recruited during pregnancy in Italy and Spain, and during the perinatal period in Greece. Total mercury concentrations were measured in cord blood samples by atomic absorption spectrometry. Maternal fish intake during pregnancy w…