Search results for "plant root"

showing 10 items of 232 documents

Traditional Chinese Medicine Remedy to Jury: The Pharmacological Basis for the Use of Shikonin as an Anticancer Therapy

2013

Shikonin is the major constituent of the root of Lithospermum erythrorhizon, which has been used in traditional Chinese medicine to treat external wounds, burns, or dermatitis for centuries. Nowadays, this root is commonly used as an herbal medicine against cancer. Studies carried out over the past 30 years have demonstrated that many of the effects historically associated with the use of this root have a scientific basis, with shikonin and its derivatives being responsible for its pharmacological properties. These include both anti-inflammatory and anticancer effects. While previous summaries have focused on the pharmacokinetics and toxicity of shikonin, the aim of this review is to report…

PharmacologyAntitumor activitybiologyTraditional medicinebusiness.industryOrganic ChemistryAnti-Inflammatory AgentsAntineoplastic AgentsTraditional Chinese medicineLithospermum erythrorhizonbiology.organism_classificationPlant RootsBiochemistryNeoplasmsChinese traditionalDrug DiscoveryHumansMolecular MedicineMedicineMedicine Chinese TraditionalbusinessNaphthoquinonesCurrent Medicinal Chemistry
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Secondary metabolites from the roots of Paronychia chionaea

2011

Two novel secondary metabolites, compounds (1–2) were isolated from the roots of Paronychia chionaea. On the basis of spectroscopic data including 1D and 2D NMR experiments (COSY, TOCSY, HSQC, and HMBC), and mass spectroscopy, their structures were established as 6- C-[α-L-arabinopyranosyl-(1→2)-β-D-glucopyranosyl]-7- O-[β-D-glucopyranosyl]-luteolin 3′-methyl ether (1), and 2-(methoxy)-2-(3,5-dimethoxy 4-hydroxyphenyl)-ethane-1,2-diol 1- O-β-D-glucopyranoside (2).

PharmacologyMagnetic Resonance SpectroscopyStereochemistryPlant ScienceGeneral MedicineChrysoeriolmedicine.diseasePlant RootsParonychiachemistry.chemical_compoundComplementary and alternative medicinechemistryDrug DiscoverymedicineGlycosidesParonychiaTwo-dimensional nuclear magnetic resonance spectroscopyHeteronuclear single quantum coherence spectroscopy
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Cycloartane-type saponins from astragalus tmoleus var. tmoleus

2016

Five known cycloartane-type glycosides were isolated from the roots of A. tmoleus Boiss. var. tmoleus. The identification of these compounds was mainly achieved by 1D and 2D NMR spectroscopic techniques and FABMS. The results of our studies confirm that triterpene saponins with the cycloartane-type skeleton might be chemotaxonomically significant for the genus Astragalus.

Pharmacologychemistry.chemical_classificationMagnetic Resonance SpectroscopybiologyTraditional medicinePlant roots010405 organic chemistryGlycosidePlant ScienceGeneral MedicineFabaceaeAstragalus PlantSaponinsbiology.organism_classification01 natural sciencesPlant Roots0104 chemical sciences010404 medicinal & biomolecular chemistryAstragalusComplementary and alternative medicinechemistryTriterpeneGenusDrug DiscoveryAstragalus Plant
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Arabidopsis copper transport protein COPT2 participates in the crosstalk between iron deficiency responses and low phosphate signaling

2013

[EN] Copper and iron are essential micronutrients for most living organisms because they participate as cofactors in biological processes, including respiration, photosynthesis, and oxidative stress protection. In many eukaryotic organisms, including yeast (Saccharomyces cerevisiae) and mammals, copper and iron homeostases are highly interconnected; yet, such interdependence is not well established in higher plants. Here, we propose that COPT2, a high-affinity copper transport protein, functions under copper and iron deficiencies in Arabidopsis (Arabidopsis thaliana). COPT2 is a plasma membrane protein that functions in copper acquisition and distribution. Characterization of the COPT2 expr…

PhysiologyArabidopsisPlant SciencePlant RootsMembranes Transport and BioenergeticsGene Expression Regulation PlantArabidopsisThalianaHomeostasisArabidopsis thalianaSLC31 ProteinsGene-expressionCation Transport ProteinsChlorosisbiologyRevealsIron DeficienciesMetal homeostasisPlantsPlants Genetically ModifiedUp-RegulationTransport proteinPhenotypeBiochemistrySignal TransductionIronRecombinant Fusion ProteinsSaccharomyces cerevisiaechemistry.chemical_elementSaccharomyces cerevisiaeModels BiologicalPhosphatesEthyleneGeneticsmedicineBIOQUIMICA Y BIOLOGIA MOLECULARFamilyIron deficiency (plant disorder)Arabidopsis ProteinsBiological TransportRoot elongationSequence Analysis DNAbiology.organism_classificationmedicine.diseaseCopperPlant LeavesAcquisitionchemistrySeedlingsStarvationMutationCopper deficiencyCopper
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The Arabidopsis COPT6 Transport Protein Functions in Copper Distribution Under Copper-Deficient Conditions

2013

Copper (Cu), an essential redox active cofactor, participates in fundamental biological processes, but it becomes highly cytotoxic when present in excess. Therefore, living organisms have established suitable mechanisms to balance cellular and systemic Cu levels. An important strategy to maintain Cu homeostasis consists of regulating uptake and mobilization via the conserved family of CTR/COPT Cu transport proteins. In the model plant Arabidopsis thaliana, COPT1 protein mediates root Cu acquisition, whereas COPT5 protein functions in Cu mobilization from intracellular storage organelles. The function of these transporters becomes critical when environmental Cu bioavailability diminishes. Ho…

PhysiologyMolecular Sequence DataSaccharomyces cerevisiaeMutantArabidopsisSaccharomyces cerevisiaePlant SciencePlant RootsCofactorCell membraneGene Expression Regulation PlantArabidopsisOrganellemedicineHomeostasisAmino Acid SequenceSLC31 ProteinsbiologyArabidopsis ProteinsMembrane transport proteinCell MembraneGenetic Complementation TestMembrane Transport ProteinsBiological TransportCell BiologyGeneral MedicinePlants Genetically Modifiedbiology.organism_classificationUp-RegulationTransport proteinCell biologyPlant LeavesMutagenesis Insertionalmedicine.anatomical_structureBiochemistrySeedsbiology.proteinPlant Vascular BundleSequence AlignmentCopperPlant ShootsPlant and Cell Physiology
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Functional characterization of the plastidial 3-phosphoglycerate dehydrogenase family in Arabidopsis.

2013

This work contributes to unraveling the role of the phosphorylated pathway of serine (Ser) biosynthesis in Arabidopsis (Arabidopsis thaliana) by functionally characterizing genes coding for the first enzyme of this pathway, 3-phosphoglycerate dehydrogenase (PGDH). We identified two Arabidopsis plastid-localized PGDH genes (3-PGDH and EMBRYO SAC DEVELOPMENT ARREST9 [EDA9]) with a high percentage of amino acid identity with a previously identified PGDH. All three genes displayed a different expression pattern indicating that they are not functionally redundant. pgdh and 3-pgdh mutants presented no drastic visual phenotypes, but eda9 displayed delayed embryo development, leading to aborted emb…

PhysiologyMutantMolecular Sequence DataArabidopsisPlant SciencePlant RootsGene Expression Regulation EnzymologicSerineBiochemistry and MetabolismGene Expression Regulation PlantComplementary DNAArabidopsisGeneticsSerineArabidopsis thalianaMetabolomicsAmino Acid SequencePlastidsPhosphorylationGenePhosphoglycerate DehydrogenasePhylogenyTapetumMicroscopy ConfocalbiologySequence Homology Amino AcidArabidopsis ProteinsReverse Transcriptase Polymerase Chain ReactionGenetic Complementation Testfood and beveragesPlant Components Aerialbiology.organism_classificationPlants Genetically ModifiedPhenotypeIsoenzymesBiochemistryMultigene FamilyMutationSeedsPollenPlant physiology
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Dynamic of the genetic structure of bacterial and fungal communities at different developmental stages of Medicago truncatula Gaertn. cv. Jemalong li…

2006

International audience; The genetic structure of bacterial and fungal communities was characterized in the rhizosphere of Medicago truncatula Gaertn. cv. Jemalong line J5 at five developmental stages (three vegetative and two reproductive stages), and in three compartments (bulk soil, rhizosphere soil and root tissues). The genetic structure of microbial communities was determined by cultivation-independent methods using directly extracted DNA that was characterized by automated ribosomal intergenic spacer analysis (ARISA). Principal component analyses (PCA) indicate that, for all developmental stages, the genetic structure of microbial communities differed significantly by compartment, wit…

PhysiologyRibosomal Intergenic Spacer analysisBulk soilPopulation geneticsPlant ScienceBiologyPlant RootsRhizobiaSoil03 medical and health sciencesSymbiosisMycorrhizaeMedicago truncatulaBotanyMICROBIAL COMMUNITIESEcosystem030304 developmental biology2. Zero hunger0303 health sciencesRhizosphereGENETIC STRUCTUREBacteriaSYMBIOTIC ASSOCIATIONSMEDICAGO TRUNCULATAPLANT DEVELOPMENTFungiANALYSE COMPOSANTE PRINCIPALE04 agricultural and veterinary sciences15. Life on landbiology.organism_classificationMedicago truncatula[SDV.BV.PEP]Life Sciences [q-bio]/Vegetal Biology/Phytopathology and phytopharmacySTADE DEVELOPPEMENTGenetic structure040103 agronomy & agriculture0401 agriculture forestry and fisheriesRhizome
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Detection of a plant enzyme exhibiting chlorogenate-dependant caffeoyltransferase activity in methanolic extracts of arbuscular mycorrhizal tomato ro…

2012

When Glomus intraradices-colonised tomato roots were extracted in methanol at 6 degrees C, chlorogenic acid (5-caffeoylquinic acid), naturally present in the extract, was slowly converted by transesterification into methyl caffeate. The progress of the reaction could be monitored by HPLC. The reaction only occurred when the ground roots were left in contact with the hydro-alcoholic extract and required the presence of 15-35% water in the mixture. When the roots were extracted in ethanol, chlorogenic acid was transformed to ethyl caffeate in the same conditions. The reaction was also detected in Glomus mosseae-colonised tomato root extracts. It was also detectable in non-mycorrhizal root ext…

Physiology[SDV]Life Sciences [q-bio]Arbuscular mycorrhizal fungiPlant SciencePlant RootsSubstrate SpecificityACBIOSYNTHESISchemistry.chemical_compoundTRANSFERASESolanum lycopersicumMycorrhizaeMethyl caffeateSWEET-POTATO ROOTSFood scienceEnzyme InhibitorsGlomusChromatography High Pressure LiquidPlant ProteinsbiologyTemperaturePlant physiologyfood and beveragesChlorogenic acidBiochemistryFUNGUSCOFFEE[SDE]Environmental SciencesGENESMETABOLISMCaffeoyltransferaseTomatoCaffeic AcidsChlorogenic acidTransferasesGenetics[SDV.BV]Life Sciences [q-bio]/Vegetal BiologyEnzyme AssaysEthanolEsterificationPlant ExtractsfungiEthyl caffeatePlant Components Aerialbiology.organism_classificationRootsEnzyme assayEnzyme ActivationPhenylmethylsulfonyl FluorideTransesterificationchemistrybiology.proteinMethanolCAFFEIC ACIDCATALYZED SYNTHESIS
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Localized versus systemic effect of arbuscular mycorrhizal fungi on defence responses to Phytophthora infection in tomato plants

2002

Development of biological control for plant diseases is accepted as a durable and environmentally friendly alternative for agrochemicals. Arbuscular mycorrhizal fungi (AMF), which form symbiotic associations with root systems of most agricultural, horticultural and hardwood crop species, have been suggested as widespread potential bioprotective agents. In the present study the ability of two AMF (Glomus mosseae and Glomus intraradices) to induce local or systemic resistance to Phytophthora parasitica in tomato roots have been compared using a split root experimental system. Glomus mosseae was effective in reducing disease symptoms produced by P. parasitica infection, and evidence points to …

Phytophthora0106 biological sciencesGlycoside HydrolasesPhysiologyPlant SciencePlant Roots01 natural sciences[SDV.BV.BOT] Life Sciences [q-bio]/Vegetal Biology/BotanicsSolanum lycopersicumSymbiosisBotanyMycorrhizaSymbiosisPhycomycetesComputingMilieux_MISCELLANEOUSGlomusPlant Diseases2. Zero hungerbiologySuperoxide Dismutasebeta-GlucosidaseChitinasesfungiFungifood and beveragesGlucan 13-beta-Glucosidase04 agricultural and veterinary sciences[SDV.BV.BOT]Life Sciences [q-bio]/Vegetal Biology/BotanicsPhytophthora nicotianaebiology.organism_classificationImmunity InnateIsoenzymesOxidative StressChitinase040103 agronomy & agriculturebiology.protein0401 agriculture forestry and fisheriesPhytophthoraSolanaceaeSignal TransductionCONTROLE DE MALADIES010606 plant biology & botanyJournal of Experimental Botany
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Crotonic acid as a bioactive factor in carrot seeds (Daucus carota L.)

2004

Water extracts from the carrot seed (Daucus carota L.) var. Perfekcja exhibit plant growth inhibitory properties against cress, cucumber, onion and carrot in a dose-dependant manner. This property results from the action of low-and high-molecular components of the extract. The low-molecular component was identified as crotonic acid ((E)-2-butenoic acid). Its presence was also confirmed in other late varieties of carrot. The determined strong herbicidal properties of crotonic acid and its availability after release to soil combined with its high level in seeds suggest that it might be considered as an allelopathic and autotoxic factor in the seeds.

Plant growthMagnetic Resonance SpectroscopyumbelliferaePlant ScienceHorticulturePlant RootsBiochemistrychemistry.chemical_compoundautotoxic activityOnionsCrotonic acidBotanyBioassayherbicidal activityMolecular BiologyAllelopathyDose-Response Relationship DrugMolecular StructurebiologyHerbicidesPlant ExtractsLiliaceaefood and beveragesGeneral MedicinePesticidebiology.organism_classificationHypocotylDaucus carotaHorticulturechemistrycrotonic acidCrotonatesallelopathyBrassicaceaeSeedsCucumis sativusDaucus carotaPhytochemistry
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