Search results for "plastic"

Evaluation of anti-androgenic activity of di-(2-ethylhexyl)phthalate

2005

International audience; DEHP is a widely used platiciser in the manufacture of PVC-based materials. It is known to disrupt the reproductive tract development in male rats. We have performed the Hershberger assay with DEHP on an immature castrated rat model to check if DEHP antagonise the testosterone propionate androgenic effect on the accessory sex organs development. DEHP significantly decreased the BC/LA muscles, the prostate, and the seminal vesicles relative weights from 100, 200, and 400 mg/kg bw/day, respectively. DEHP increased the liver relative weight from 100 mg/kg bw/day. A study was also performed on MDA-MB453 cell line stably transfected with pMMTVneo-Luc with DEHP and its maj…

A controlled and versatile NCA polymerization method for the synthesis of polypeptides

2013

A versatile and simple methodology for the preparation of well-defined polyglutamate nanocarriers is described. For the first time ammonium salts with non-nucleophilic tetrafluoroborate anions are used as initiators for the ring opening polymerization of alpha-N-carboxyanhydrides (NCAs) allowing a multigram scale polyglutamate synthesis with defined molecular weight (up to 800 units), low polydispersity (<1.2), controlled chain end functionality and adequate stereoselectivity and absence of any trace of toxic impurity to allow biomedical applications.

Conformation of a chain polyelectrolyte in solution with low molecular weight salt: small angle neutron scattering measurements

1986

Small angle neutron scattering measurements have been carried out on the tetramethylammonium salt of the polystyrenesulfonic acid withDP w =310 and 1060 in water solution with tetramethylammonium chloride with ionic strength between 0.02 M and 1.0 M. The scattering curves in the scattering vector range 0.05 nm−1≤Q≤1.8nm−1 have been fitted using the form factor of a worm-like chain of finite thickness. The conformational parameters mean square radius of gyration, statistic chain element, mass per unit length and mean square radius of the cross-section have been determined experimentally and used for describing the conformation of the coils. By these molecular weights and ionic strengths, exc…

Cytotoxic phytochemicals from the crude extract of Tetrapleura tetraptera fruits towards multi-factorial drug resistant cancer cells.

2020

Abstract Ethnopharmacological relevance Tetrapleura tetraptera is an African medicinal spice used in traditional medicine to treat several ailments including cancer. Aim of the study The present study was designed to evaluate the cytotoxicity of the dichloromethane-methanol (1:1) extract of the fruits of Tetrapleura tetraptera (TTF) and its constituents: (3R, 4S)-3,4-dimethyloxetan-2-one (1), luteolin (2), stigmasterol (4), 3-O-[6′-O-undecanoyl-β-D-glucopyranosyl]stigmasterol (6), olean-12-en-3-β-O-D-glucopyranoside (7), 3-O-β-D-glucopyranosyl-(1 → 6)-β-D-glucopyranosylurs-12-en-28-oic acid (8), 3-O-β-D-glucopyranosyl-(1 → 3)-β-D-glucopyranosyl-27-hydroxyolean-12-ene-28-oic acid (9), methyl…

2-Hydroxyoleic Acid Induces ER Stress and Autophagy in Various Human Glioma Cell Lines

2012

Background: 2-Hydroxyoleic acid is a synthetic fatty acid with potent anti-cancer activity which does not induce undesired side effects. However, the molecular and cellular mechanisms by which this compound selectively kills human glioma cancer cells without killing normal cells is not fully understood. The present study was designed to determine the molecular bases underlying the potency against 1321N1, SF-767 and U118 human glioma cell lines growth without affecting non cancer MRC-5 cells. Methodology/Principal Findings: The cellular levels of endoplasmic reticulum (ER) stress, unfolded protein response (UPR) and autophagy markers were determined by quantitative RT-PCR and immunoblotting …

Magnetic Resonance Imaging and Ultrasound Evaluation after Breast Autologous Fat Grafting Combined with Platelet-Rich Plasma

2014

Zinc oxide application in the textile industry: surface tailoring and water barrier attributes as parameters with direct implication in comfort perfo…

2013

The present study focuses on surface tailoring and water barrier attributes of zinc oxide (ZnO)-polyester composite textile materials. The surface properties, such as surface topography and roughness, composite compositions as well as thermal stability of ZnO-100% polyester textile composite materials treated through a padding process with different concentrations of ZnO dispersions as active agent in water and methanol were studied. The results show that 3% ZnO-textile composite material have enhanced water barrier properties compared with the other compositions; a fact which promises improved properties in terms of comfort. ZnO modification of polyester surfaces leads to a dramatic decre…

Evaluation of dermal toxicity of antibacterial cotton textile coated by sol-gel technology

2017

AbstractThis paper reports about cotton textile modification by sol-gel technology with the purpose of obtaining antibacterial properties, evaluation of antibacterial properties and dermal toxicity tests of cotton textile with Zn and Si coating. Antibacterial properties evaluation against pathogenic microorganisms Pseudomonas aeruginosa, Staphylococcus aureus, and Escherichia coli made using the Parallel streak method in accordance with ATCC147 standard. For more specific evaluation of the coated textile, in vitro cytotoxicity test with epidermal HaCat cells was done. It is concluded that the coatings containing Zn and Si obtained by the sol-gel technology can impart antibacterial propertie…

Integrazione di celle fotovoltaiche ibride nel vetromattone

2012

L’invenzione riguarda l’integrazione del vetromattone con celle solari ibride (organiche/inorganiche), conosciute come Dye-sensitized Solar Cell (DSC). La combinazione del vetromattone con le DSC consente di migliorare le prestazioni del prodotto originario rendendolo in grado di produrre energia pulita. Le caratteristiche di trasparenza e isolamento termo-acustico del prodotto possono essere regolate agendo sulla configurazione delle DSC. Il prodotto può essere assemblato a formare pannelli fotovoltaici per la realizzazione di facciate traslucide energeticamente “attive” in varie condizioni luminose (condizioni di luce diffusa o artificiale) e indipendentemente dall’angolo di radiazione so…

Pannello precompresso di vetromattoni assemblati a secco per la realizzazione di involucri traslucidi

2012

L’invenzione riguarda la realizzazione di un pannello di vetromattoni montati “a secco” -da impiegare per la realizzazione di involucri edilizi traslucidi anche nel caso di edifici alti- che è in grado di rispondere adeguatamente alle sollecitazioni orizzontali (quali quelle dovute a vento e sisma) grazie all’applicazione della tecnica della precompressione mondirezionale. Per offrire una risposta ai limiti imposti dalla tecnica di assemblaggio tradizionale dei vetromattoni (“ad umido”), l’applicazione della precompressione consente, infatti, di dare ai pannelli preassemblati “a secco” una rigidezza adeguata anche in direzione normale al loro piano di posa, sfruttando le buone caratteristic…