Search results for "plates"
showing 10 items of 123 documents
Post-Buckling Analysis of Damaged Multilayered Composite Stiffened Plates by Rayleigh-Ritz Method
2016
A Rayleigh-Ritz approach for the analysis of buckling and post-buckling behavior of cracked composite stiffened plates is presented. The structure is modeled as the assembly of plate elements modeled by the first order shear deformation theory and taking geometric nonlinearities into account through the von Karman’s theory assumptions. Continuity along the plate elements connected edges and the enforcement of rigid and elastic restraints of the plate boundaries are obtained by using penalty techniques, which also allow to straightforwardly implement efficient crack modeling strategies. General symmetric and unsymmetric stacking sequences are considered and numerical procedures have been dev…
Volar and dorsal mid-shaft forearm plating using DCP and LC-DCP: interference with the interosseous membrane and forearm-kinematics.
2010
Purpose To clarify if dorsal plate osteosynthesis of the forearm shaft is associated with impingement of the interosseous membrane (IOM) and if rotational kinematics of the forearm are influenced. Background Forearm fractures are treated by separate incisions. Osteosynthesis via one approach in proximal forearm fractures was associated with higher rates of synostosis. It has been claimed that this is due to IOM impingement. Materials and methods 16 forearms of fresh frozen cadavers were dissected until only radius, ulna and the IOM remained. To preserve physiological forearm rotation, the elbow joint, the distal radio-ulnar joint and the carpus remained intact. In group 1, LC-DC and DC plat…
Dynamic response of equivalent orthotropic plate model for stiffened plate: numerical-experimental assessment
2017
Abstract Over the last two decades, homogenization-based modeling techniques have attracted considerable attention. In fact, through these methods, structures such as corrugated or stiffened plates, commonly referred to as structurally orthotropic plates, can be approximately studied as equivalent flat plates with orthotropic behavior. Specifically, these homogenization techniques allow for the direct determination of the equivalent flexural and torsional rigidities which appear in the governing equation for the deflection of the equivalent orthotropic plate. It is worth noting that, the determined equivalent material properties retain the dependence on the geometric parameters of the origi…
The microsomal epoxide hydrolase has a single membrane signal anchor sequence which is dispensable for the catalytic activity of this protein
1994
The microsomal epoxide hydrolase (mEH) catalyses the hydrolysis of reactive epoxides which are formed by the action of cytochromes P-450 from xenobiotics. In addition it has been suggested that mEH might mediate the transport of bile acids. For the mEH it has been shown that it is co-translationally inserted into the endoplasmic reticulum. Here we demonstrate that the N-terminal 20 amino acid residues of this protein serve as its single membrane anchor signal sequence and that the function of this sequence can also be supplied by a cytochrome P-450 (CYP2B1) anchor signal sequence. The evidence supporting this conclusion is as follows: (i) the rat mEH and a CYP2B1-mEH fusion protein, in whic…
The Large Area Detector onboard the eXTP mission
2018
The eXTP (enhanced X-ray Timing and Polarimetry) mission is a major project of the Chinese Academy of Sciences (CAS) and China National Space Administration (CNSA) currently performing an extended phase A study and proposed for a launch by 2025 in a low-earth orbit. The eXTP scientific payload envisages a suite of instruments (Spectroscopy Focusing Array, Polarimetry Focusing Array, Large Area Detector and Wide Field Monitor) offering unprecedented simultaneous wide-band X-ray spectral, timing and polarimetry sensitivity. A large European consortium is contributing to the eXTP study and it is expected to provide key hardware elements, including a Large Area Detector (LAD). The LAD instrumen…
Baseline design of the filters for the LAD detector on board LOFT
2014
The Large Observatory for X-ray Timing (LOFT) was one of the M3 missions selected for the phase A study in the ESA's Cosmic Vision program. LOFT is designed to perform high-time-resolution X-ray observations of black holes and neutron stars. The main instrument on the LOFT payload is the Large Area Detector (LAD), a collimated experiment with a nominal effective area of ~10 m 2 @ 8 keV, and a spectral resolution of ~240 eV in the energy band 2-30 keV. These performances are achieved covering a large collecting area with more than 2000 large-area Silicon Drift Detectors (SDDs) each one coupled to a collimator based on lead-glass micro-channel plates. In order to reduce the thermal load onto …
Influence of agents that act on DNA and RNA synthesis on the activity of poly(ADP-Rib) polymerase
1975
The activity of poly(ADP-Rib) polymerase is enhanced in the presence of spermine and spermidine. Among the adenosine-like antibiotics tested, only formycin B and showdomycin cause an inhibition of the enzyme, which is competitive to NAD. The activity of poly(ADP-Rib) polymerase is not reduced by rifamycin, alpha-amanitin and 2-phenylethanol.
Self-assembly of metallosupramolecular rhombi from chiral concave 9,9'-spirobifluorene-derived bis(pyridine) ligands.
2014
Two new 9,9’-spirobifluorene-based bis(4-pyridines) were synthesised in enantiopure and one also in racemic form. These ligands act as concave templates and form metallosupramolecular [(dppp)2M2L2] rhombi with cis-protected [(dppp)Pd]2+ and [(dppp)Pt]2+ ions. The self-assembly process of the racemic ligand preferably occurs in a narcissistic self-recognising manner. Hence, a mixture of all three possible stereoisomers [(dppp)2M2{(R)-L}2](OTf)4, [(dppp)2M2{(S)-L}2](OTf)4, and [(dppp)2M2{(R)-L}{(S)-L}](OTf)4 was obtained in an approximate 1.5:1.5:1 ratio which corresponds to an amplification of the homochiral assemblies by a factor of approximately three as evidenced by NMR spectroscopy and m…
A multidomain approach of the SBEM in the plate bending analysis
2009
The aim of this paper is to apply the multidomain approach of the SBEM to the plate bending analysis. The plate is subdivided into macro-elements connected each other along the interface boundary. Every macro-element is defined by an elastic relation which connects the generalized shear force and moments at the interface to the nodal displacements and rotations of the same boundary and to the loads. This approach allows a considerable reduction of the variables through a condensation process which leaves the interface kinematical unknowns, only. The assembly process may be obtained through the regularity conditions prescribed at the interface.
A symmetric Galerkin BEM for plate bending analysis
2009
Abstract The Symmetric Galerkin Boundary Element Method is employed in thin plate bending analysis in accordance with the Love–Kirchhoff kinematical assumption. The equations are obtained through the stationary conditions of the total potential energy, written for a plate whose boundary is discretized in boundary elements. Since the matrix coefficients are made up as double integrals with high order singularities, a strategy is shown to compute these coefficients in closed form. Furthermore, in order to model the kinematical discontinuities and to weight the mechanical quantities along the boundary elements, the Lagrangian quadratic shape functions, rather than C 1 type (spline, Hermitian),…