Search results for "polyphenol"

showing 10 items of 514 documents

Effect of summer pruning on some fruit quality traits in Hayward kiwifruit

2013

Introduction . The aim of our study was to analyze the effect of various levels of light availability in the fruit microenvironment (induced by summer pruning) on some fruit quality traits. Materials and methods . Two levels of summer pruning were set: removal of either 30% or 60% of the canopy leaf area. These treatments were compared with the control (unpruned vines). Two canopy layers (upper and lower) were identified in each treatment and in the control vines. At harvest, yield per cane and per shoot was recorded in the two canopy layers; fruit fresh weight, flesh firmness, total soluble solid content and total titratable acidity were measured. Fruit Total Antioxidant Capacity (TAC) and…

Canopydefoliationantioxidantleaf area indexActinidia deliciosaFleshCrop yieldfungifood and beveragesTitratable acidfruitHorticultureBiologySettore AGR/03 - Arboricoltura Generale E Coltivazioni ArboreeHorticulturecultivationqualityYield (wine)ShootBotanyLeaf area indexAgronomy and Crop SciencePruningpolyphenolsFood Science
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POMOLOGICAL TRAITS, SENSORY CHARACTERISTICS, AND ANTIOXIDANT ACTIVITY IN FRUITS OF NINE LOQUAT CULTIVARS GROWN IN SICILY

2015

Loquat cultivation in Italy currently aims at offering a wider choice of cultivars to growers. The present study determined commercial quality, characterized the antioxidant capacity, and quantified the major bioactive compounds of some local ('BRT 20', 'Claudia', 'Nespolone di Trabia', 'Sanfilippara') and international ('Algerie', 'El Buenet', 'Bueno', 'Golden Nugget' and 'Peluche') cultivars. Fruit was harvested at commercial ripening and chemical-physical determinations of weight, diameters, skin and flesh color, soluble solid content, tritable acidity, antioxidant activity and polyphenol content, and sensory analyses were carried out. Data showed a large variability among genotypes and …

CarotenoidPolyphenolFruit qualityAntioxidantmedicine.medical_treatmentPlant compositionTitratable acidSettore AGR/15 - Scienze E Tecnologie AlimentariHorticultureBiologySettore AGR/03 - Arboricoltura Generale E Coltivazioni ArboreeHorticultureEriobotrya japonicaPolyphenolSoluble solidsSettore BIO/10 - BiochimicamedicineCrop qualityBioactive compoundCultivarChemical compositionActa Horticulturae
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High pressure processing of carrot juice: Effect of static and multi-pulsed pressure on the polyphenolic profile, oxidoreductases activity and colour.

2020

Abstract The aim of this study was to determine the influence of static and multi-pulsed hydrostatic pressure processing (HPP) treatments on the polyphenolic profile, oxidoreductase activity, colour, and browning index of carrot juice. Phenolic acids, flavonoids, lignans and other polyphenols were the predominant polyphenols detected with Triple-TOF-LC-MS/MS. The highest concentration of ferulic acid, didymin, dihydro-p-coumaric acid, sesaminol and matairesinol isomers were found among all the compounds detected. After HPP treatment, irrespective of the pressures applied, new simple polyphenols like oleuropein, 4-vinylsyringol, isocoumarin, and 4-hydroxybenzaldehyde were detected. Both phen…

Carrot juiceHydrostatic pressureColorBlood Pressure01 natural sciencesAnalytical ChemistryFerulic acidPascalizationchemistry.chemical_compound0404 agricultural biotechnologyOleuropeinTandem Mass SpectrometryBrowningFood scienceMatairesinol010401 analytical chemistryfood and beveragesPolyphenols04 agricultural and veterinary sciencesGeneral Medicine040401 food science0104 chemical sciencesDaucus carotachemistryPolyphenolCatechol OxidaseFood ScienceChromatography LiquidFood chemistry
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Inhibitory effects oftrans-resveratrol analogs molecules on the proliferation and the cell cycle progression of human colon tumoral cells

2008

International audience; Resveratrol may function as a cancer chemopreventive agent. However, few data are available on the antitumoral activities of its dimer, epsilon-viniferin, also present in human diet. So, the effects of resveratrol, epsilon-viniferin, of their acetylated forms (resveratrol triacetate, epsilon-viniferin pentaacetate) and of vineatrol (a wine grape extract) were compared on human adenocarcinoma colon cells. Resveratrol and resveratrol triacetate inhibit cell proliferation and arrest cell cycle. epsilon-Viniferin and epsilon-viniferin pentaacetate slightly reduce cell proliferation. Vineatrol inhibits cell proliferation and favors an accumulation in the S phase of the ce…

Cell Membrane Permeabilityendocrine system diseasesvineatrolMESH: Cell CycleMESH: DNA ReplicationMESH: Flow CytometryresveratrolResveratrolMESH : Antineoplastic Agents PhytogenicWine grapechemistry.chemical_compoundMESH: Structure-Activity RelationshipMESH: StilbenesStilbenesMESH : Structure-Activity RelationshipMESH: Cell Membrane Permeabilityskin and connective tissue diseasesfood and beveragesDNA NeoplasmMESH : Cell DivisionCell cycleFlow CytometryMESH : Colonic Neoplasmscolon cancerBiochemistryColonic NeoplasmsMESH: Cell Divisioncell cycleMESH : DNA NeoplasmCell Divisionhormones hormone substitutes and hormone antagonistsMESH : DNA ReplicationBiotechnologyDNA ReplicationMESH: XenobioticsMESH: Cell Line TumorMESH : Flow CytometryMESH: Antineoplastic Agents PhytogenicMESH: DNA NeoplasmMESH : XenobioticsBiologyXenobioticsMESH : StilbenesStructure-Activity RelationshipCell Line TumorMESH : Cell Cycle[SDV.BBM] Life Sciences [q-bio]/Biochemistry Molecular BiologyHumansStructure–activity relationship[SDV.BBM]Life Sciences [q-bio]/Biochemistry Molecular Biology[ SDV.BBM ] Life Sciences [q-bio]/Biochemistry Molecular BiologypolyphenolsS phaseMESH: Colonic NeoplasmsMESH: HumansMESH : Cell Line TumorCell growthorganic chemicalsMESH : HumansAntineoplastic Agents PhytogenicchemistryMESH : Cell Membrane PermeabilityAcetylationCell cultureCancer researchFood ScienceMolecular Nutrition & Food Research
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Targeting multiple myeloma with natural polyphenols

2019

Multiple myeloma (MM) is still an incurable hematologic malignancy. Although new therapeutic strategies have been developed to target different pathways in malignant cells, such as proliferation, differentiation, and apoptosis, better survival rates have also been achieved by the introduction of autologous stem cell transplantation (ASCT). Hematopoietic stem cell transplantation and novel targeted agents, such as proteasome inhibitors, monoclonal antibodies, immunomodulatory drugs, check-point inhibitors and epigenetic modulators, have significantly achieved long remission time and increased survival rates. However, most patients relapse, develop resistance, and eventually die because of re…

Cell Survivalmedicine.drug_classmedicine.medical_treatmentHematopoietic stem cell transplantationMonoclonal antibody01 natural sciencesNatural polyphenols Multiple myeloma Anticancer drug03 medical and health sciencesAutologous stem-cell transplantationDrug DiscoverymedicineAnimalsHumansEpigeneticsMultiple myelomaCell Proliferation030304 developmental biologyPharmacologyBiological Products0303 health sciences010405 organic chemistryDrug discoveryChemistryOrganic ChemistryTherapeutic effectPolyphenolsfood and beveragesCancerGeneral Medicinemedicine.diseaseSettore CHIM/08 - Chimica FarmaceuticaAntineoplastic Agents Phytogenic0104 chemical sciencesSettore BIO/14 - FarmacologiaCancer researchMultiple MyelomaEuropean Journal of Medicinal Chemistry
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Effects of Zizyphus lotus L. (Desf.) polyphenols on Jurkat cell signaling and proliferation.

2013

We assessed the effects of Zizyphus lotus L. (Desf.) polyphenols (ZLP) on T-cell signaling and proliferation. Our results showed that ZLP exerted no effect on the increases in intracellular free calcium concentrations, [Ca(2+)]i, in human Jurkat T-cells. However, ZLP modulated the thapsigargin-induced increases in [Ca(2+)]i in these cells. ZLP treatment was found to decrease the phosphorylation of extracellular signal-regulated kinase 1/2 (ERK1/2). In addition, ZLP induced a rapid (t1/2=33s) and dose-dependent decrease in intracellular pH (pHi) in human Jurkat T-cells. Furthermore, ZLP significantly curtailed T-cell proliferation by diminishing their progression from S to G2/M phase of cell…

Cell signalingIntracellular pHT-LymphocytesImmunologychemistry.chemical_elementCalciumBiologyJurkat cellsJurkat CellsExtracellularImmunology and AllergyHumansCalcium SignalingRNA MessengerExtracellular Signal-Regulated MAP KinasesCell ProliferationPharmacologyImmunosuppression TherapyInflammationKinasePolyphenolsZiziphusCell cycleCell biologyBiochemistrychemistryGene Expression RegulationFruitPhosphorylationInterleukin-2ThapsigarginInternational immunopharmacology
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Effects of irrigation on fruit ripening behavior and metabolic changes in olive

2012

Olive (Olea europaea, cv Leccino) fruits grown under different water regimes were analyzed by metabolomics and specific transcript accumulation analyses. The fruit from non-irrigated (rain-fed) and irrigated trees cultivated under field conditions, with a seasonal water amount equivalent to the calculated crop evapotranspiration (ETc) was compared in the last developmental phase and, in particular, at commercial harvest. Metabolomics (GC-MS) analysis identified several hundred metabolites in ripe mesocarp, 46 of which showed significantly different contents in the rain-fed and irrigated samples. Some compounds involved in primary metabolism (carbohydrates, amino acids, organic acids) and se…

Chalcone synthasePhenylalanine ammonia-lyaseHorticultureBiologychemistry.chemical_compoundSettore AGR/07 - Genetica AgrariaBotanyMetabolomicsSecondary metabolismOlea europaeaIrrigationfood and beveragesPolyphenolsRipeningbiology.organism_classificationFruit ripeningdevelopmental stage enzyme activity evapotranspiration fruit gene expression hydrological regime irrigation system metabolism metabolite phenol physiological response phytochemistry pigment ripening terpeneFruit ripening Irrigation Metabolomics Olea europaea PolyphenolsHorticulturechemistryCycloartenol synthasePolyphenolOleaAnthocyaninbiology.proteinOlea europaea Oleaceae
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Availability of polyphenols in fruit beverages subjected to in vitro gastrointestinal digestion and their effects on proliferation, cell-cycle and ap…

2009

Abstract Three fruit beverages: Fb (grape–orange–apricot), FbFe (Fb + iron sulphate) and FbFeM (FbFe + skimmed milk) were subjected to in vitro gastrointestinal digestion. Addition of Fe and milk decreased the phenolic content of Fb by 13% and 55%, respectively. The digestion process decreased the phenolic content by 47%, 60%, and 70% in Fb, FbFe and FbFeM with respect to the initial, non-digested, Fb. Caco-2 cells were incubated for 4 h daily for four days or continuously for 24 h with bioaccessible fractions obtained after the digestion (digests). Polyphenols were not metabolised by Caco-2 cells. Fb digest (∼50 μM total phenolics) was the sample that led to the highest inhibition of cell …

ChemistryCell growthfood and beveragesGeneral MedicineCell cycleAnalytical ChemistryBioavailabilityBiochemistryCaco-2ApoptosisPolyphenolFood scienceDigestionIncubationFood ScienceFood Chemistry
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Use of Nanomaterials as Alternative for Controlling Enzymatic Browning in Fruit Juices

2020

Abstract Polyphenol oxidase (PPO) enzyme, present in most of fruits and vegetables, frequently induces browning in juices and beverages during postharvest and processing. Many efforts have been done to prevent or avoid this reaction. Nevertheless, the development of new methods is still of interest since many of the current methods present important drawbacks. An overview of the exiting techniques to inhibit enzymatic browning has been compiled in this chapter, including physical (i.e., thermal treatments, high pressures, irradiation, ultrasonication, pulsed electric fields, and ultrafiltration) and chemical techniques (acidification, addition of antibrowning agents) but with particular att…

ChemistrySonicationFruits and vegetablesBrowningUltrafiltrationPostharvestFood sciencePolyphenol oxidaseSilver nanoparticleNanomaterials
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Effetti dell’essiccamento sull’attività polifenolossidasica e pattern antiossidante di pomodoro ciliegino(Effects of drying process on polyphenol oxi…

2010

Cherry tomato dryng polyphenol oxidase antioxidant activity lycopene phenols ascorbic acid
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