Search results for "porter"

Astrocytes and hypothalamic glucose sensing: metabolic role and involvement of astroglial connexins

2012

The hypothalamus plays a pivotal role in the nervous control of glucose homeostasis. This area contains gluco-sensitive neurons. Some of them detect increases in glucose levels and regulate glucose homeostasis by stimulating insulin secretion or inhibiting food intake. It is widely accepted that astrocytes are metabolically coupled to neurons. Lactate, resulting from the metabolism of glucose by astrocytes, is transported via the monocarboxylate transporters (MCTs). In addition, gap junctions (GJ), that form networks within astrocytes, are essential to transfer glucose from the bloodstream to the active neurons. These astroglial GJ mainly consist of connexins 43 and 30 (Cxs).The aims of my …

Arbuscular mycorrhiza (AM): the first glomeromycotan sugar transporter is characterized by using the unique geosiphon symbiosis with cyanobacteria to…

2007

International audience; In the arbuscular mycorrhizas (AM), the symbiotic interface is the site of nutrient exchange where the mycobiont receives up to 20% of the photosynthates of the photobiont as carbohydrates. We have, for the first time, functionally characterised a monosaccharide transporter type, represented by GpMST1, putatively playing a role in this process (Schüßler, A., Martin, H., Cohen, D., Fitz, M., and Wipf, D. 2006. Characterization of a carbohydrate transporter from symbiotic glomeromycotan fungi. Nature 444:933-936.). Together with the arbuscular mycorrhizal (AM) fungi, forming endomycorrhiza with the majority of land plants, Geosiphon pyriformis belongs to the Glomeromyc…

Photosynthesis mediates expression of Sorghum bicolor transporters in arbuscular mycorrhizal symbiosis

2014

Expression of Sorghum bicolor ammonium transporters upon colonization with arbuscular mycorrhizal fungi

2012

Arbuscular mycorrhizal fungi (AMF) are important plant symbionts, trading mineral nutrients beyond the reach of roots, in particular ammonium, in exchange to their host’s photosynthetic products. Sorghum bicolor is one of the world's leading cereal crops, providing food, fibre and fuel across a range of environments and production systems. It has a particular ability to be productive even under strongly adverse conditions, tolerating much more severe drought than most other grain crops. As its genome has recently been sequenced, we have characterized all eight members of the ammonium transporter (AMT) family and studied their expression in different tissues of field-grown plants. While most…

Sulfate transporters in the plant’s response to drought and salinity: regulation and possible functions

2014

International audience; Drought and salinity are two frequently combined abiotic stresses that affect plant growth, development, and crop productivity. Sulfate, and molecules derived from this anion such as glutathione, play important roles in the intrinsic responses of plants to such abiotic stresses. Therefore, understanding how plants facing environmental constraints re-equilibrate the flux of sulfate between and within different tissues might uncover perspectives for improving tolerance against abiotic stresses. In this review, we took advantage of genomics and post-genomics resources available in Arabidopsis thaliana and in the model legume species Medicago truncatula to highlight and …

Les fanzines : un média identitaire des groupes de supporters Ultras de football.

2007

National audience

Les stratégies de gestion identitaire chez les groupes de supporters en rugby : l'avènement du phénomène ultra ? In V. Bonnet (Ed.), Rugby, medias & …

2010

Distinct 5' SCL enhancers direct transcription to developing brain, spinal cord, and endothelium: neural expression is mediated by GATA factor bindin…

1999

The SCL gene encodes a basic helix-loop-helix transcription factor with a pivotal role in the development of endothelium and of all hematopoietic lineages. SCL is also expressed in the central nervous system, although its expression pattern has not been examined in detail and its function in neural development is unknown. In this article we present the first analysis of SCL transcriptional regulation in vivo. We have identified three spatially distinct regulatory modules, each of which was both necessary and sufficient to direct reporter gene expression in vivo to three different regions within the normal SCL expression domain, namely, developing endothelium, midbrain, and hindbrain/spinal …

Context-dependent Pax-5 repression of a PU.1/NF-κB regulated reporter gene in B lineage cells

2001

Enhancers located in the 3' end of the locus in part regulate immunoglobulin heavy chain (IgH) gene expression. One of these enhancers, HS 1,2, is developmentally regulated by DNA binding proteins like NF-kappaB, Pax-5 and the protein complex NF-alphaP in B lineage cells. Here we report that NF-alphaP is the ets protein PU.1. A glutathione-S-transferase (GST)-pulldown assay demonstrated that PU.1 can physically interact with NF-kappaB in solution. Experiments in COS cells showed that PU.1 and NF-kappaB (p50/c-Rel) can activate transcription of an enhancer linked reporter gene. The paired domain protein Pax-5 has previously been shown to repress enhancer-dependent transcription. Additional c…

Social Interactions of Dat-Het Epi-Genotypes Differing for Maternal Origins: The Development of a New Preclinical Model of Socio-Sexual Apathy

2021

Social interaction is essential for life but is impaired in many psychiatric disorders. We presently focus on rats with a truncated allele for dopamine transporter (DAT). Since heterozygous individuals possess only one non-mutant allele, epigenetic interactions may unmask latent genetic predispositions. Homogeneous “maternal” heterozygous offspring (termed MAT-HET) were born from dopamine-transporter knocked-out (DAT-KO) male rats and wild-type (WT) mothers