Search results for "prognostic"

TUMORI a CELLULE GERMINALIin ETA' PEDIATRICA: FATTORI PROGNOSTICI del PROTOCOLLO AIEOP TCG 91.

2002

CIRCA IL 20% DEI PAZIENTI CON TUMORI A CELLULE GERMINALI (tcg) SONO RESISTENTI AL TRATTAMENTO. GLI aUTORI HANNO EFFETTUATO UNO STUDIO POLICENTRICO AL FINE DI RILEVARE CORRELAZIONI TRA PARAMETRI CLINOCO/LABORATORISTICI E LA PROGNOSI

A Review on Approaches for Condition Based Maintenance in Applications with Induction Machines located Offshore

2012

Published version of an article in the journal: Modeling, Identification and Control. Also available from the publisher at: http://dx.doi.org/10.4173/mic.2012.2.4 Open access This paper presents a review of different approaches for Condition Based Maintenance (CBM) of induction machines and drive trains in offshore applications. The paper contains an overview of common failure modes, monitoring techniques, approaches for diagnostics, and an overview of typical maintenance actions. Although many papers have been written in this area before, this paper puts an emphasis on recent developments and limits the scope to induction machines and drive trains applied in applications located offshore.

Nivolumab VERSUS Cabozantinib as Second-Line Therapy in Patients With Advanced Renal Cell Carcinoma: A Real-World Comparison

2022

Background: Tyrosine-kinase inhibitors (TKIs) still represent a first-line option for selected patients with metastatic Renal Cell Carcinoma (mRCC). We aimed to compare the real-world efficacy of nivolumab or cabozantinib as second-line therapy in specific mRCC subpopulations. Patients and Methods: We retrospectively collected data from 11 centers from Italy, Spain and US. Overall Survival (OS) and Progression-Free Survival (PFS) were analyzed using Kaplan-Meier curves. Cox proportional models were used at univariate and multivariate analyses. Results: We collected data from 343 patients with mRCC, 123 (36%) treated with cabozantinib and 220 (64%) with nivolumab. The median OS resulted long…

Valore prognostico della TC coronarica nella routine clinica: follow-up a 24 mesi in 166 pazienti con sospetta o nota aterosclerosi coronarica.

2010

Use of Machine Learning and Artificial Intelligence to Drive Personalized Medicine Approaches for Spine Care

2020

Personalized medicine is a new paradigm of healthcare in which interventions are based on individual patient characteristics rather than on “one-size-fits-all” guidelines. As epidemiological datasets continue to burgeon in size and complexity, powerful methods such as statistical machine learning and artificial intelligence (AI) become necessary to interpret and develop prognostic models from underlying data. Through such analysis, machine learning can be used to facilitate personalized medicine via its precise predictions. Additionally, other AI tools, such as natural language processing and computer vision, can play an instrumental part in personalizing the care provided to patients with …

Tumor infiltration by chemokine receptor 7 (CCR7)+ T-lymphocytes is a favorable prognostic factor in metastatic colorectal cancer

2012

The immune interactions occurring within the tumor microenvironment have a critical role in determining the outcome of colorectal cancer patients. We carried-out an immunohistochemical analysis of tumor infiltrating T-lymphocytes expressing chemokine receptor 7 (CCR7) in a series of colorectal cancer patients enrolled in a prospective clinical trial. We demonstrated that a high tumor infiltration score of this lymphocyte subset is predictive of longer progression free survival and overall survival. © 2012 Landes Bioscience.

Urinary MicroRNA Profiling Predicts the Development of Microalbuminuria in Patients with Type 1 Diabetes

2015

Microalbuminuria provides the earliest clinical marker of diabetic nephropathy among patients with Type 1 diabetes, yet it lacks sensitivity and specificity for early histological manifestations of disease. In recent years microRNAs have emerged as potential mediators in the pathogenesis of diabetes complications, suggesting a possible role in the diagnosis of early stage disease. We used quantiative polymerase chain reaction (qPCR) to evaluate the expression profile of 723 unique microRNAs in the normoalbuminuric urine of patients who did not develop nephropathy (n = 10) relative to patients who subsequently developed microalbuminuria (n = 17). Eighteen microRNAs were strongly associated w…

Economic value of a local museum

2004

Abstract The aim of this paper is to determine the economic value of a local cultural history museum, namely, the Museum of Central Finland in Jyvaskyla. This study also seeks to clarify what factors affect the willingness-to-pay for the Museum. Data were gathered from a sample of Jyvaskyla residents aged 18 and over via a postal questionnaire in November and December 1997. The results indicate that in reality, Jyvaskyla residents contribute less in taxes to the Museum than they report that they are willing to pay. This indicates that at least the present amount of tax revenue can justifiably be directed to the Museum. Maintenance of the Museum can thus be legitimised on the basis of the pu…

Weather sensor fault detection in meteorological masts

2020

Wind power has become the world’s fastest growing renewable technology. The world-wide wind power installed capacity has exceeded 597 GW, and the new installations during the last three years was an average of 50 GW per year. A major issue with wind power system and with meteorological masts is the relatively high cost of operation and maintenance (OM). Wind turbines and sensor towers are hard-to-access structures, and they are often located in remote areas. That’s why continuous monitoring of wind turbine health using automated failure detection algorithms can improve turbine reliability and reduce maintenance costs by detecting failures before they reach a catastrophic stage and by elimin…

Factors related to the relative survival of patients with diffuse large B-cell lymphoma in a population-based study in France: does socio-economic st…

2017

IF 7.702; International audience; The survival of patients with diffuse large B-cell lymphoma has increased during the last decade as a result of addition of anti-CD20 to anthracycline-based chemotherapy. Although the trend is encouraging, there are persistent differences in survival within and between the USA and European countries suggesting that non-biological factors play a role. Our aim was to investigate the influence of such factors on relative survival of patients with diffuse large B-cell lymphoma. We conducted a retrospective, multicenter, registry-based study in France on 1165 incident cases of diffuse large B-cell lymphoma between 2002 and 2008. Relative survival analyses were p…