Search results for "respect"

showing 10 items of 52 documents

Comparing Long-Acting Antipsychotic Discontinuation Rates Under Ordinary Clinical Circumstances: A Survival Analysis from an Observational, Pragmatic…

2021

Background Recent guidelines suggested a wider use of long-acting injectable antipsychotics (LAI) than previously, but naturalistic data on the consequences of LAI use in terms of discontinuation rates and associated factors are still sparse, making it hard for clinicians to be informed on plausible treatment courses. Objective Our objective was to assess, under real-world clinical circumstances, LAI discontinuation rates over a period of 12 months after a first prescription, reasons for discontinuation, and associated factors. Methods The STAR Network ‘Depot Study’ was a naturalistic, multicentre, observational prospective study that enrolled subjects initiating a LAI without restrictions …

MalePediatricsrespectively)0302 clinical medicineDelayed-Action PreparationBrief Psychiatric Rating ScalePharmacology (medical)he STAR Network ‘Depot Study’ prospectively followed 394 subjects initiating treatment with long-acting injections (LAIs) of antipsychotics under naturalistic conditions for 12 months. LAI discontinuation was frequent in everyday clinical practice in ItalyOriginal Research ArticleProspective StudiesProspective cohort studytreatmentMental DisordersHazard ratiowhereas more than half of participants initiating risperidone LAI and olanzapine LAI discontinued during the 12 months of follow-up (51.4 and 62.5%Psychiatric Status Rating ScaleMiddle Agedside efectsPsychiatry and Mental healthItalyMental DisorderFemalehe STAR Network ‘Depot Study’ prospectively followed 394 subjects initiating treatment with long-acting injections (LAIs) of antipsychotics under naturalistic conditions for 12 months. LAI discontinuation was frequent in everyday clinical practice in Italy occurring in almost 40% of the entire sample; side efects participant refusal to continue LAIs and LAIs no longer being required were the most frequently reported reasons for discontinuation. Paliperidone LAI and aripiprazole LAI were the least discontinued medications (33.9 and 35.4% respectively) whereas more than half of participants initiating risperidone LAI and olanzapine LAI discontinued during the 12 months of follow-up (51.4 and 62.5% respectively). In multivariate analysis being prescribed olanzapine LAI and poor medication adherence at baseline were signifcantly associated with higher discontinuation risk.HumanAntipsychotic Agentsmedicine.drugPsychopathologyAdultmedicine.medical_specialtyDiscontinuationFollow-Up StudieMedication Adherence03 medical and health sciencesmedicineHumansPaliperidoneAdverse effectSettore MED/25 - Psichiatriadiscontinuation ratesPsychiatric Status Rating Scalesrespectively). In multivariate analysisbusiness.industryLong-Acting Antipsychoticlong-acting injectable antipsychoticsSurvival AnalysisConfidence intervalparticipant refusal to continue LAIs and LAIs no longer being required were the most frequently reported reasons for discontinuation. Paliperidone LAI and aripiprazole LAI were the least discontinued medications (33.9 and 35.4%030227 psychiatryDiscontinuationProspective StudieAntipsychotic Agentoccurring in almost 40% of the entire sampleDelayed-Action PreparationsNeurology (clinical)business030217 neurology & neurosurgerybeing prescribed olanzapine LAI and poor medication adherence at baseline were signifcantly associated with higher discontinuation riskFollow-Up Studies
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Esquisse d'une réforme sur la réparation des dommages subis par un sportif

2021

International audience

Mutualisation de l'indemnisation des accidents[SHS.DROIT]Humanities and Social Sciences/Law[SHS.DROIT] Humanities and Social Sciences/LawRéformeResponsabilité CivileNon-respect du droit à la sécuritéComputingMilieux_MISCELLANEOUS
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Integration of both the derivatives with respect to P-paths and approximative derivatives

2009

In the present paper, in terms of generalized absolute continuity, we present a descriptive characteristic of the primitive with respect to a system of P-paths and study the relationship between the Denjoy-Khinchin integral and the Henstock H P-integral. © 2009 Pleiades Publishing, Ltd.

Pure mathematicsDenjoy-Khinchin integralMeasurable setGeneral MathematicsCalculusDerivative with respect to P-pathHenstock H P-integralMathematics (all)Absolute continuityAbsolute continuityBaire theoremMathematics
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Même prononcée dans l'intérêt du service, même concernant un militaire, une mutation peut porter atteinte au droit au respect de la vie privée et fam…

2012

International audience

Respect de la vie privée et familiale[SHS.DROIT]Humanities and Social Sciences/Law[SHS.DROIT] Humanities and Social Sciences/LawCARRIERE DES AGENTS PUBLICSSITUATIONS STATUTAIRESMutationComputingMilieux_MISCELLANEOUS
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La sentenza Di Sarno e altri c. Italia: un ulteriore passo avanti della Corte di Strasburgo nell'affermazione di obblighi di protezione dell'ambiente

2013

The work analyses the Di Sarno and others v. Italy ruling made by the European Court of Human Rights. After a brief description of the case, the author focuses on the main elements of the ruling showing the Court’s propensity to foster the safeguard of instances in the field of environmental protection. In particular, the elements examined are: the fact that the Court makes explicit reference to the right to enjoy a healthy and safe environment, the ready attribution of the victim status to the applicants, the assessment concerning the serious and direct interference with the applicant’s private sphere, the question concerning a lack of proof of a threat to an individual’s health and well-b…

Right to respect for private and family lifepositive obligationobblighi positiviright to environmentDiritto al rispetto della vita privata e familiareSettore IUS/13 - Diritto Internazionaleart. 8 della Convenzione europea dei diritti dell'uomo.art. 8 of the European Convention of Human Rights.diritto all'ambiente
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La decadenza nel diritto del lavoro tra vicende traslative e fattispecie interpositorie

2020

L’art. 32 della legge n. 183/2010 ha sollevato molteplici questioni applicative legate alla sua infelice formulazione. Il saggio analizza il controverso perimetro applicativo del comma 4, lett. c) e d), inerenti rispettivamente la cessione del contratto di lavoro avvenuta ai sensi dell’art. 2112 c.c. e i casi in cui si chieda la costituzione o l’accertamento di un rapporto di lavoro in capo a un soggetto diverso dal titolare del contratto. L’Autore fornisce le coordinate per una corretta interpretazione, opportunamente restrittiva, delle previsioni decadenziali alla luce del dato letterale e del diritto dell’Unione europea.

Settore IUS/07 - Diritto Del LavoroArt. 32 L. 183/2010 raises several questions related to its application mainly due to its poor drafting. This essay analyses the controversial issue of the meaning of paragraph 4 letter c) and letter d) which concern respectively the transfer of the employment contract in accordance with Art. 2112 Civil Code and the creation and/or the ascertaining of an employment relationship with someone other than the holder of the contract. The Author provides the coordinates for a proper and duly restrictive understanding of the norms on limitation in the light of its literal interpretation and in accordance with EU law.
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On fixed points of alpha-eta-psi-contractive multifunctions

2014

Recently Samet et al. [B. Samet, C. Vetro, P. Vetro, Fixed point theorem for alpha-psi-contractive type mappings, Nonlinear Anal., 75 (2012), 2154{2165] introduced the notion of alpha-psi-contractive type mappings and established some fixed point theorems in complete metric spaces. Succesively, Asl et al. [J.H. Asl, SH. Rezapour, N. Shahzad, On fixed point of alpha-contractive multifunctions, Fixed Point Theory Appl., 2012, 212 (2012)] introduced the notion of alpha_*-psi-contractive multifunctions and give a fixed point result for these multifunctions. In this paper we obtain certain new fixed point and common fixed point theorems via alpha_*-admissible multifuncions with respect to eta. T…

Settore MAT/05 - Analisi MatematicaMetric spaces alpha_*-admissible multifuncions with respect to a function eta pair of multifunctions alpha_*-admietassible with respect to a function eta fixed points common fixed points.
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Respect and hope a binomial relationship supporting the creation of a true entrepreneurial model

2009

Il paper riflette sul ruolo delle virtù del rispetto e della speranza rispetto all'efficacia dell'azione imprenditoriale e quindi con riferimento alla funzione specifica esercitata

Settore SECS-P/07 - Economia AziendaleRespect hope entrepreneurial virtues
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DECORIN EFFECTS ON PROTEOMIC PROFILING OF BREAST CANCER CELLS: AN UPDATED STUDY

2015

The malignant carcinomas are characterized by several capabilities acquired by the neoplastic cells, among which the ability to invade the extracellular matrix (ECM) and to establish a crosstalk with several ECM components. Under this respect, the extracellular microenvironment is an entity extraordinarily rich of information with opposite signals. Our group has long undertaken the study of the effects of ECM molecules on the behavior of cancer cells in vitro. Among the studied molecules, the decorin was found to exert a non-permissive effect on the growth and motility of the transfected tumor cells. The decorin, belongs to the family of small leucine-rich proteoglycans (SLRP) and is involv…

The malignant carcinomas are characterized by several capabilities acquired by the neoplastic cells among which the ability to invade the extracellular matrix (ECM) and to establish a crosstalk with several ECM components. Under this respect the extracellular microenvironment is an entity extraordinarily rich of information with opposite signals. Our group has long undertaken the study of the effects of ECM molecules on the behavior of cancer cells in vitro. Among the studied molecules the decorin was found to exert a non-permissive effect on the growth and motility of the transfected tumor cells. The decorin belongs to the family of small leucine-rich proteoglycans (SLRP) and is involved physiologically in the fibrillogenesis of collagen. In the last few year a new anti-oncogenic role has been proposed for decorin1. This study aimed to implement the knowledge on the effects of ectopic decorin on breast cancer cells using as a reference point the results already achieved by our research group2 on the experimental model format. By breast cancer cell line 8701-BC and its transfected clone DEC-C2. The extension of the proteomic analysis combined with the mass spectrometry allowed to triplicate the number of identified proteins in our model. Among the newly identified proteins were members of the classes of metabolic enzymes S100 family and cell motility proteins which revealed a net decrease in the decorin transfected cells. Of considerable importance is the observation that these classes of proteins are the most involved in metastatic progression. These results confirm and reinforce the anti-oncogenic role hypothesized for decorin. The work was co-funded by the Italian 5x1000 to COBS.DECORIN
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Ambiente e diritto penale: brevi riflessioni fra le modifiche agli artt.9 e 41 Cost. e le prospettive di riforma in ambito internazionale

2023

l contributo analizza l’impatto che il recente inserimento dell’ambiente in Costituzione può dispiegare in ambito penale, tanto rispetto all’ambiente quale oggetto della tutela penale, quanto sul versante della selezione dei modelli di illecito, soffermandosi in particolare sul problema delle possibili ricadute penalistiche del nuovo vincolo di solidarietà ecologica di tipo intergenerazionale. Seguendo il fil rouge del bene giuridico, la seconda parte del saggio ricostruisce invece i punti critici e le prospettive di sviluppo del diritto penale ambientale internazionale, alla luce della nozione di ambiente quale bene giuridico comune ed universale.

The paper analyses the impact that the recent inclusion of the environment in the Italian Constitution may have in the criminal law both with respect to the criminally relevant notion of the environment and with regard to the selection of the types of criminal offences. From this point of view the paper also takes into consideration the penal significance of the new bond of intergenerational ecological solidarity. Following the file rouge of the “bene giuridico” the second part of the essay is instead dedicated to the description of the critical points and the possible developments of international environmental criminal law in the light of a conception of the environment as a common and universal legal good.Settore IUS/17 - Diritto Penale
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