Search results for "restriction"
showing 10 items of 527 documents
Alterations in eating behavior in patients with substance abuse disorders
2018
RESUMEN La comorbilidad psiquiátrica entre los trastornos de la conducta alimentaria (TCA) y los trastornos por uso de sustancias (TUS) suele darse con frecuencia, complicando el tratamiento y pronóstico de ambos. En el presente trabajo se estudió la prevalencia de los trastornos alimentarios en pacientes que demandan tratamiento por un TUS, principalmente alcohol, cocaína y cannabis, así como el papel modulador de la impulsividad y la adicción a la restricción alimentaria. Los instrumentos utilizados fueron la escala de impulsividad de Barratt, el Inventario de Trastornos Alimenticios (EDI) y el Cuestionario Valencia de Adicción a la Restricción (CVAR). Los resultados muestran que los paci…
In a randomized trial in prostate cancer patients, dietary protein restriction modifies markers of leptin and insulin signaling in plasma extracellul…
2017
Obesity, metabolic syndrome, and hyperleptinemia are associated with aging and age-associated diseases including prostate cancer. One experimental approach to inhibit tumor growth is to reduce dietary protein intake and hence levels of circulating amino acids. Dietary protein restriction (PR) increases insulin sensitivity and suppresses prostate cancer cell tumor growth in animal models, providing a rationale for clinical trials. We sought to demonstrate that biomarkers derived from plasma extracellular vesicles (EVs) reflect systemic leptin and insulin signaling and respond to dietary interventions. We studied plasma samples from men with prostate cancer awaiting prostatectomy who particip…
Bene : Adverb or noun?
2013
International audience; When Italian bene ‘good / well’ occurs with fare ‘do / make’, several constructs with remarkably different argument frames are involved. This paper deals with three of them: (a) Il latte fa bene ai bambini ‘Milk is good for children’; (b) Fa bene il suo lavoro ‘She does her job well’, and (c) Faresti bene a non dire niente ‘You would do well to say nothing about it’. We discuss dictionary discrepancies concerning the lexical category of 'bene' in (a), which we take to be a noun predicate, and draw a distinction between the adverbial uses in (b) and (c).
La interacción de los códigos en doblaje: juegos de palabras y restricciones visuales
2012
El siguiente artículo profundiza en la complejidad del trasvase del humor, basándose en un problema recurrente en el doblaje de comedias: los juegos de palabras transmitidos parcialmente a través de la imagen. El estudio analiza los factores que inciden en su traducción e ilustra las distintas técnicas de traducción con escenas de la filmografía de los Hermanos Marx. Finalmente, muestra las conclusiones obtenidas a partir del análisis del doblaje de 74 juegos de palabras con restricción visual y su comparación con 116 casos en los que no hay dicha restricción. The following paper delves into the complex transfer of humour, focusing on a recurring problem that appears when dubbing comedies: …
Sophisticated humor against COVID-19 : the Polish case
2021
Abstract The analysis undertaken in the article focuses on a group of memes selected from the database which drew on culture-specific references. Specifically, they embrace the memories of socialist times and call on references to comic films and easily recognized characters in order to bring out the re-discovered absurdity of the current COVID-19 situation. This material seems ideal to revisit Raskin’s early notion of sophistication, which was broadly argued to derive from intertextuality as well complexity of references that function as sources of humor. In all the examples discussed we can observe the intertextual and metatextual elements, multiple levels and shifts in points of view and…
IL-6 -174G/C polymorphism and IL-6 serum levels in patients with liver cirrhosis and hepatocellular carcinoma.
2011
Recently, a link between high levels of circulating IL-6 and hepatocellular carcinoma (HCC) has been proposed. In addition, single nucleotide polymorphisms (SNPs) in the promoter region of the IL-6 gene have been reported to be related to several inflammatory-related conditions, including cancer. The purpose of this article is: (1) to evaluate the frequencies of SNPs in the IL-6 promoter region at position -174 and IL-6 serum levels in a group of patients with HCC and underlying liver cirrhosis (LC), and compare them with a group of LC patients without HCC; (2) to determine whether a possible correlation exists between the allelic variations, IL-6 serum levels, and the risk of developing HC…
Identification of Cpgp40/15 Type Ib as the Predominant Allele in Isolates of Cryptosporidium spp. from a Waterborne Outbreak of Gastroenteritis in So…
2006
ABSTRACT Cryptosporidium sp. isolates from a waterborne outbreak of diarrhea in France were analyzed by PCR-restriction fragment length polymorphism analysis and sequencing of the Cpgp40/15 locus. Ninety-one percent of the isolates were Cryptosporidium hominis type Ib. The results of this study and those of studies of other outbreaks suggest that the type Ib allele is the predominant allele associated with waterborne cryptosporidiosis.
Major histocompatibility complex class I-restricted activation of cloned T cells by a soluble protein in the absence of accessory cells.
1989
A T-cell clone, 10BK.1, was established from the draining lymph nodes of (B10 x B10.BR)F1 mice immunized with ovalbumin (OVA) according to standard protocols. Upon coculture with the antigen, 10BK.1 cells reacted by production of lymphokines and by proliferation despite the absence of additional antigen-presenting cells. These T cells do not express major histocompatibility complex (MHC) class II molecules on the cell surface as assessed on the basis of several criteria: by cytofluorometric analysis I-A and I-E determinants were not detectable; 10BK.1 cells could not act as antigen-presenting cells for long-term-cultured MHC class II-restricted T-cell clones; and monoclonal antibodies direc…
Requirements of Exogenous Protein Antigens for Presentation to CD4+ T lymphocytes By MHC Class II-Positive APC
1993
The antigen-specific activation of CD4-positive T helper cells depends on the recognition of a complex of MHC class II molecules and an antigen-derived peptide on the surface of antigen-presenting cells (APC). For most antigens generation of this MHC/peptide complex requires the uptake of the respective antigen by APC, followed by intracellular processing. The latter leads to suitable peptides of the antigen which are able to bind to MHC class ll-molecules. Subsequently the resulting complexes are transported to the cell surface. Evidence supporting this concept came mainly from the finding that agents such as chloroquine1, interfering with the function of endosomes and lysosomes, can block…
Moderate weight loss attenuates chronic endoplasmic reticulum stress and mitochondrial dysfunction in human obesity
2018
Abstract Objective In obese patients undergoing caloric restriction, there are several potential mechanisms involved in the improvement of metabolic outcomes. The present study further explores whether caloric restriction can modulate endoplasmic reticulum (ER) stress and mitochondrial function, as both are known to be mechanisms underlying inflammation and insulin resistance (IR) during obesity. Methods A total of 64 obese patients with BMI ≥35 kg/m2 underwent a dietary program consisting of 6 weeks of a very-low-calorie diet followed by 18 weeks of low-calorie diet. We evaluated changes in the metabolic and inflammatory markers -TNFα, hsCRP, complement component 3 (C3c), and retinol bindi…