Search results for "rigidity"
showing 10 items of 83 documents
A comparative review of CASE shells: A preliminary framework and research outcomes
1993
Abstract Because of rigidity and weak support of the user's native methods and methodologies in existing CASE tools, there is a growing need for customizable CASE tools (CASE shells). The nature of CASE shells is different from ordinary CASE tools supporting a fixed set of methods. With CASE shells, organizations can define tools to support their own methods, instead of choosing a tool that supports them. Existing CASE shells have different features and architectural principles that make them appropriate for different tasks. Obviously, a framework for comparing them is needed. In this paper we develop one such framework. It takes into account different tasks in customization and the effecti…
A Note on the Shear Influence on Belt Drive Mechanics
2007
Abstract Belt drives work often with short center distances and very different wrap arcs so that high adherence characteristics are required at the belt-pulley contact. In addition, the belt flexural stiffness reduces the contact width, but this decrease may be compensated in part by the belt softening due to the shear compliance.
Dynamic evaluation of aggregation and agglutination of red blood cells.
1984
Viscoelastic evaluation of aggregation and agglutination of red blood cells was attempted. A concentric double cylinder viscoelastometer was used for determining the dynamic rigidity modulus and loss modulus of blood sample. The dynamic rigidity modulus of horse blood were measured over a wide range of hematocrit. The relation between the viscoelastic behavior and the erythrocyte sedimentation was examined. The change in the amount of surface charge of enzyme treated red blood cells was qualitatively estimated from the measurements of dynamic viscoelasticity of red blood cells suspension with added poly-L-lysine. The dynamic rigidity modulus of red blood cells agglutinated by adding lectin …
Bond length compressibility in hard ReB2 investigated by x-ray absorption under high pressure
2010
International audience; This work describes x-ray absorption measurements under high pressure in ReB2 , complemented by ab initio calculations. The EXAFS analysis yields the average Re–B bond compressibility, which turns out to be χReB = 5.6(9) × 10− 4 GPa−1 . Combining this information with previous x-ray diffraction experiments we have characterized the network of covalent bonds responsible for the rigidity of the structure. The main conclusion is that the compression is anisotropic and nonhomogeneous, reflecting bonding differences between Re–B and B–B bonds and also between nonequivalent Re–B bonds. The layer defined by boron atoms tends to become flatter under high pressure. As a conse…
The Important Role of the Nuclearity, Rigidity, and Solubility of Phosphane Ligands in the Biological Activity of Gold(I) Complexes
2018
A series of 4-ethynylaniline gold(I) complexes containing monophosphane (1,3,5-triaza-7-phosphaadamantane (pta; 2), 3,7-diacetyl-1,3,7-triaza-5-phosphabicyclo[3.3.1]nonane (3), and PR3 , with R=naphthyl (4), phenyl (5), and ethyl (6)) and diphosphane (bis(diphenylphosphino)acetylene (dppa; 7), trans-1,2-bis(diphenylphosphino)ethene (dppet; 8), 1,2-bis(diphenylphosphino)ethane (dppe; 9), and 1,3-bis(diphenylphosphino)propane (dppp; 10)) ligands have been synthesized and their efficiency against tumor cells evaluated. The cytotoxicity of complexes 2-10 was evaluated in human colorectal (HCT116) and ovarian (A2780) carcinoma as well as in normal human fibroblasts. All the complexes showed a hi…
Topological optimization of a structural naval component manufactured in FDM
2019
In this paper, a topological optimization procedure has been applied on a real component of the deck of a sailing multi-hull in order to find the internal shape that best save the material used in the manufacturing process without a relevant loss of structural rigidity. The multi-hull boat is a 16 feet length catamaran equipped with an asymmetric foil on both centerboards and with a symmetric foil on both rudders. The task of the analyzed object is to act as a cylindrical support for the screw that drives the rotation of the centerboard. The process adopted to manufacture this object is the Fused Deposition Modeling (FDM) technique, because of its high versatility and its relative low-cost …
Oligothienoacenes versus oligothiophenes: Impact of ring fusion on the optical properties
2010
The impact of backbone rigidity on the optical properties of thiophene-based compounds is studied by analyzing in detail the geometrical, electronic, optical and vibronic features of a family of oligothienoacenes (nnTAs) in comparison to non-fused α-oligothiophenes (nnTs) by means of quantum-chemical calculations. Ring fusion in nnTAs provokes a greater conjugation in the ground state. However, the change in the bond length alternation upon electronic excitation is very similar in both systems, which is also reflected in a similar evolution of the first optical transition energy with increasing oligomer size. Larger transition energies in nnTAsvs.nnTs arise from an electronic effect rather …
Experimental Evidence of Leaks in Elastic Pipes
2016
Several studies have been carried out in recent decades to establish a relationship between total head and leaks. In literature, the leakage governing equations have been analysed in light of pipe materials, water head, leak dimension or shape. Most of these contributions questioned the classical Torricelli equation, demonstrating through experimental evidence that the classical orifice law can give unsatisfactory results. Nevertheless, starting from the Torricelli equation, other exponential or linear governing equations have been proposed as mathematical models able to reproduce the leakages in water distribution systems (WDSs). To investigate the validity of the proposed governing equati…
New Hyperekplexia Mutations Provide Insight into Glycine Receptor Assembly, Trafficking, and Activation Mechanisms*
2013
Hyperekplexia is a syndrome of readily provoked startle responses, alongside episodic and generalized hypertonia, that presents within the first month of life. Inhibitory glycine receptors are pentameric ligand-gated ion channels with a definitive and clinically well stratified linkage to hyperekplexia. Most hyperekplexia cases are caused by mutations in the α1 subunit of the human glycine receptor (hGlyR) gene (GLRA1). Here we analyzed 68 new unrelated hyperekplexia probands for GLRA1 mutations and identified 19 mutations, of which 9 were novel. Electrophysiological analysis demonstrated that the dominant mutations p.Q226E, p.V280M, and p.R414H induced spontaneous channel activity, indicat…
The influence of wearing ski-boots with different rigidity characteristics on postural control
2018
External supports that reduce ankle joint mobility such as ski-boots can impair postural control of healthy participants. Although this disruptive effect has been attributed to the rigidity of the external supports, the results remained controversial and no study has been conducted in order to evaluate the influence of ski-boots rigidity. Hence, the question about the influence of ankle support rigidity on postural control remains open. This study was therefore undertaken in order to investigate the effect of ski-boots rigidity on postural control. Ten healthy active participants were recruited. The wearing of soft and rigid ski-boots was compared to barefoot while standing on a seesaw gene…