Search results for "risk factor"

showing 10 items of 4321 documents

30 Years on: How the Neurodevelopmental Hypothesis of Schizophrenia Morphed into the Developmental Risk Factor Model of Psychosis

2017

At its re-birth 30 years ago, the neurodevelopment hypothesis of schizophrenia focussed on aberrant genes and early neural hazards, but then it grew to include ideas concerning aberrant synaptic pruning in adolescence. The hypothesis had its own stormy development and it endured some difficult teenage years when a resurgence of interest in neurodegeneration threatened its survival. In early adult life, it over-reached itself with some reductionists claiming that schizophrenia was simply a neurodevelopmental disease. However, by age 30, the hypothesis has matured sufficiently to incorporated childhood and adult adversity, urban living and migration, as well as heavy cannabis use, as importan…

Striatal dopaminePsychosismedicine.medical_specialtyDopamineSynaptic pruningDiseaseHistory 21st CenturyRisk factor model03 medical and health sciences0302 clinical medicinesociodevelopmentmedicineHumansrisk factorsPsychiatryUrban livingPsychiatryneurodevelopmentdopamine neurodevelopment risk factors sociodevelopment Dopamine History 20th Century History 21st Century Humans Psychiatry Psychotic Disorders SchizophreniaHistory 20th Centurymedicine.disease030227 psychiatryPsychiatry and Mental healthAdult lifemedicine.anatomical_structurePsychotic DisordersSchizophreniaSchizophreniadopaminePsychology030217 neurology & neurosurgeryRegular ArticlesClinical psychology
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Risk Factors and treatment needs of batterer intervention program participants with substance abuse problems

2021

espanolEl objetivo de este estudio fue identificar los principales factores de riesgo y necesidades de tratamiento de los participantes en un programa de intervencion con maltratadores (BIP) con problemas de abuso de alcohol y/o drogas (ADAP), mas alla de sus problemas de abuso de substancias, teniendo en cuenta cuatro conjuntos de variables: sociodemograficas (i.e., edad, nivel educativo, ingresos, empleo y estatus de inmigrante), trastornos de personalidad y ajuste psicologico (i.e., sintomatologia clinica, trastornos de personalidad, ira, impulsividad y autoestima), variables socio-relacionales (i.e., apoyo comunitario, apoyo intimo, eventos vitales estresantes y rechazo social percibido…

Substance abusealcohol abuseAlcohol abuseintimate partner violenceDelinqüents RehabilitacióBatterer intervention programssubstance abuserisk factorsPsychologyApplied Psychologypartner violence offendersK5000-5582batterer intervention programsTreatment needsIntimate partner violenceBF1-990Criminal law and procedureRisk factorsParellatreatment needsDroguesPsychologyAlcoholPartner violence offendersLawHumanities
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External strength, inner weakness: main factors in child-to-parent violence

2019

[EN] Child-to-parent violence (CPV) is an increasingly frequent problem in young people, as a result of a process of social transformation and ineffective parental styles. As a consequence, it has shaped a change in the leading head within the family. The prevalence and incidence rates of CPV have increased in the recent years. For that reason, our main objective is to perform a bibliographic review in order to analyze the main axes that revolve around it, and provide information to increase the scientific studies. More specifically, this article begins by defining the CPV and its types, associated breeding styles and prevalence data in recent years. In the second chapter, the clinical, edu…

SubstancesmenoresAdolescentsBiochemistryDrogasPersonalidadterapia sistémicaChild-to-parent violencelcsh:Jurisprudence. Philosophy and theory of lawhijos maltratadoresPsychopathologySystemic therapyMaltrato05 social sciencesDrugsFamily violenceIntervenciónTerapia sistémicaMenores050902 family studiesHijos maltratadorespersonalidadintervenciónConsumoestilo de crianzamaltrato050104 developmental & child psychologyViolencia Filio-ParentalFactores de riesgoPersonalitypsicopatologíaInterventionAbuseabusoconsumodrogasfactores de riesgo0501 psychology and cognitive sciencesAdolescentesviolencia familiarEstilo de crianzaOrganic ChemistryadolescentesPsicopatologíasustanciasMinorsRisk factorsAbusolcsh:K201-4870509 other social sciencesViolencia familiarSustancias
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Recommended practice for out-of-hospital emergency anaesthesia in adults: Statement from the Out-of-Hospital Emergency Anaesthesia Working Group of t…

2016

Emergency anaesthesia is an important therapeutic measure in out-of-hospital emergency medicine. The associated risks are considerably higher than those of in-hospital anaesthesia. The primary objectives of emergency anaesthesia are hypnosis, analgesia, oxygenation and ventilation through airway management. The secondary objectives of emergency anaesthesia are amnesia, anxiolysis, the reduction of oxygen consumption and respiratory work, the protection of vital organs and the avoidance of secondary myocardial and cerebral damage. A critical evaluation of the indications for outof- hospital emergency anaesthesia must take into consideration patient, case and provider-related factors. Rapid s…

Suction (medicine)medicine.medical_specialtyEmergency Medical ServicesCritical Caremedicine.medical_treatmentlaw.invention03 medical and health sciences0302 clinical medicine030202 anesthesiologylawAnesthesiologyRisk FactorsIntensive careGermanymedicineIntubationHumansAnesthesiaSocieties MedicalCapnographymedicine.diagnostic_testbusiness.industry030208 emergency & critical care medicineRapid sequence induction3. Good healthPulse oximetryAnesthesiology and Pain MedicineAnesthesiaEmergency medicineVentilation (architecture)Practice Guidelines as TopicEmergency MedicineAirway managementbusinessEuropean journal of anaesthesiology
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Skin flap-like wounds debridement considerations: What to do in Emergency Department.

2019

Surgical repairmedicine.medical_specialtyDebridementSuturesbusiness.industrymedicine.medical_treatmentSkin flapEmergency trauma Flap necrosis Flap-like wound Surgical repairGeneral MedicineEmergency departmentSkin TransplantationSurgeryDebridementRisk FactorsEmergency MedicinemedicineFlap necrosisbusinessEmergency Service HospitalThe American journal of emergency medicine
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Language Development and Symbolic Play in Children With and Without Familial Risk for Dyslexia

2001

The purposes of this study were to investigate (a) whether children in families with a positive history of dyslexia were more likely to show delays in language development than children without family risk and (b) whether a delayed onset of expressive language (late talking) predicted later language development. We analyzed the language development of 200 children longitudinally at 14, 24, 30, and 42 months and assessed their symbolic play at 14 months. Half of the children ( N =106) were from families with a history of dyslexia (the Dyslexia Risk [DR] group), and other children served as age-matched controls. Parental reports and structured tests were used to assess children’s receptive a…

SymbolismLinguistics and LanguageLanguage delayDyslexiamedicine.diseaseLanguage acquisitionLanguage DevelopmentChild developmentLanguage and LinguisticsPlay and PlaythingsDevelopmental psychologyDyslexiaSpeech and HearingLanguage developmentCommunication disordermedicineHumansLanguage disorderRisk factorPsychologyJournal of Speech, Language, and Hearing Research
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How to manage patients with polyvascular atherosclerotic disease. Position paper of the International Union of Angiology

2020

Atherosclerosis is a systemic disease affecting multiple arterial territories. Patients with clinical atherosclerotic disease in one vascular bed are likely to have asymptomatic or symptomatic atherosclerotic lesions in other vascular beds. Specifically, peripheral arterial disease (PAD) often coexists with coronary and carotid disease. With progression of atherosclerotic disease in one vascular bed, the risk of clinical manifestations in other territories increases and the incidence of adverse cardiovascular events increases substantially with the number of affected vascular beds. Classical risk factors are associated with the development of polyvascular atherosclerotic disease (PVD) in di…

Systemic diseasemedicine.medical_specialtymedicine.medical_treatmentCardiologyDisease030204 cardiovascular system & hematology030230 surgeryRevascularizationAsymptomaticPeripheral Arterial Disease03 medical and health sciences0302 clinical medicineRisk FactorsmedicineHumansIntensive care medicineAngiologybusiness.industryIncidence (epidemiology)GuidelineAtherosclerosismedicine.diseasePosition papermedicine.symptomCardiology and Cardiovascular MedicinebusinessInternational Angiology
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Global, regional, and national burden of chronic kidney disease, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017

2020

Abstract: Background Health system planning requires careful assessment of chronic kidney disease (CKD) epidemiology, but data for morbidity and mortality of this disease are scarce or non-existent in many countries. We estimated the global, regional, and national burden of CKD, as well as the burden of cardiovascular disease and gout attributable to impaired kidney function, for the Global Burden of Diseases, Injuries, and Risk Factors Study 2017. We use the term CKD to refer to the morbidity and mortality that can be directly attributed to all stages of CKD, and we use the term impaired kidney function to refer to the additional risk of CKD from cardiovascular disease and gout. Methods Th…

Systems AnalysisGoutCost effectiveness030204 cardiovascular system & hematologyGlobal HealthGLOMERULAR-FILTRATION-RATEGlobal Burden of DiseaseCOST-EFFECTIVENESS0302 clinical medicineCause of DeathPrevalenceGlobal healthDiabetic NephropathiesRegistries030212 general & internal medicineSUB-SAHARAN AFRICA11 Medical and Health SciencesIncidenceMortality rate1. No povertyGeneral MedicineHälsovetenskaperGBD Chronic Kidney Disease CollaborationCKD-EPI EQUATION3. Good healthEuropeCardiovascular Diseases/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingQuality-Adjusted Life YearsLife Sciences & BiomedicineAsiaOceania195 COUNTRIESATHEROSCLEROSIS RISKCARDIOVASCULAR OUTCOMESRisk AssessmentArticle03 medical and health sciencesMedicine General & InternalSDG 3 - Good Health and Well-beingRISK-FACTORGeneral & Internal MedicineEnvironmental healthHealth SciencesmedicineHumansGBD chronic kidney diseaseMortalityRisk factorRenal Insufficiency ChronicDisease burdenQMScience & TechnologyAustralasiabusiness.industryPERIPHERAL ARTERIAL-DISEASEBayes Theoremmedicine.diseaseHealth SurveysQuality-adjusted life yearRENAL-DISEASELatin AmericaYears of potential life lostAfricaNorth AmericaHuman medicinebusinessRCKidney disease
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Use of Different Food Classification Systems to Assess the Association between Ultra-Processed Food Consumption and Cardiometabolic Health in an Elde…

2021

The PREDIMED-Plus trial was supported by the European Research Council (Advanced Research grant 2014–2019; agreement #340918; granted to M.Á.M.-G.); the official Spanish institutions for funding scientific biomedical research, CIBER Fisiopatología de la Obesidad y Nutrición (CIBEROBN) and Instituto de Salud Carlos III (ISCIII) through the Fondo de Investigación para la Salud (FIS) which is co-funded by the European Regional Development Fund (coordinated FIS projects led by J.S-S. and J.V., including the following projects: PI13/00673, PI13/00492, PI13/00272, PI13/01123, PI13/00462, PI13/00233, PI13/02184, PI13/00728, PI13/01090, PI13/01056, PI14/01722, PI14/00636, PI14/00618, PI14/00696, PI…

Síndrome metabólicoMaleFood processingMediterranean dietNOVAObesidadÍndice de masa corporal:Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings]0302 clinical medicineultra-processed foodMedicineTX341-641:Diseases::Pathological Conditions Signs and Symptoms::Signs and Symptoms::Body Weight::Overweight [Medical Subject Headings]Body mass indexclassification systemsIncidenceIARC:Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Data Collection::Questionnaires [Medical Subject Headings]Metabolic syndrome3. Good healthNutriciónCohortManipulación de alimentosDietaFactores de riesgo cardiometabólicoConcordanceUNC:Check Tags::Male [Medical Subject Headings]ClasificaciónClassification systemsDiet SurveysArticle03 medical and health sciencesfood processingHumans:Diseases::Cardiovascular Diseases [Medical Subject Headings]Aged030109 nutrition & dietetics:Health Care::Health Care Economics and Organizations::Organizations::International Agencies [Medical Subject Headings]:Persons::Persons::Age Groups::Adult::Middle Aged [Medical Subject Headings]PREDIMED-Plusmedicine.diseaseObesity:Diseases::Nutritional and Metabolic Diseases::Nutrition Disorders::Overnutrition::Obesity [Medical Subject Headings]Blood pressure:Check Tags::Female [Medical Subject Headings]:Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Cohort Studies [Medical Subject Headings]Linear ModelsFast FoodsMetabolic syndromeOlder people0301 basic medicineSíndrome metabòlicaFood HandlingOverweightDiet MediterraneanPersones gransCohort Studiescardiometabolic riskEndocrinología030212 general & internal medicine:Persons::Persons::Age Groups::Adult::Aged [Medical Subject Headings]2. Zero hungerMetabolic SyndromeNutrition and Dietetics:Technology and Food and Beverages::Technology Industry and Agriculture::Industry::Food Industry::Food Handling [Medical Subject Headings]:Analytical Diagnostic and Therapeutic Techniques and Equipment::Therapeutics::Nutrition Therapy::Diet Therapy::Diet Mediterranean [Medical Subject Headings]Middle Aged:Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Data Collection::Health Surveys::Nutrition Surveys::Diet Surveys [Medical Subject Headings]Female:Technology and Food and Beverages::Food and Beverages::Food::Fast Foods [Medical Subject Headings]medicine.symptom:Diseases::Nutritional and Metabolic Diseases::Metabolic Diseases::Glucose Metabolism Disorders::Hyperinsulinism::Insulin Resistance::Metabolic Syndrome X [Medical Subject Headings]Dietética y nutrición:Analytical Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Physical Examination::Body Constitution::Body Weights and Measures::Body Mass Index [Medical Subject Headings]:Phenomena and Processes::Physiological Phenomena::Nutritional Physiological Phenomena::Diet [Medical Subject Headings]:Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Data Collection::Vital Statistics::Morbidity::Incidence [Medical Subject Headings]Environmental healthMediterranean dietObesityAlimentos ultraprocesados:Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Models Statistical::Linear Models [Medical Subject Headings]NutricióNutrition:Geographical Locations::Geographic Locations::Europe::Spain [Medical Subject Headings]business.industryNutrition. Foods and food supplyCardiometabolic Risk FactorsOverweightDieta mediterráneaCardiometabolic riskUltra-processed foodDietSpainIFICSobrepesoFood processingbusinessdietFood ScienceNutrients
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The problems and promises of research into human immunology and autoimmune disease

2012

Translational research in autoimmunity is hampered by a number of hurdles, including a lack of knowledge regarding initiating and pathologically relevant autoantigens, the low frequency of autoreactive pathogenic B and T cells, difficulty in accessing the affected tissue, differences between self-reactive and pathogen-specific lymphocytes, a lack of etiologically relevant preclinical animal models and the heterogeneity of disease presentation. Given the need for biomarkers and new therapeutics, it is imperative that these hurdles be surmounted.

T-LymphocytesTranslational researchmedicine.disease_causeAutoantigensGeneral Biochemistry Genetics and Molecular BiologyAutoimmunityAutoimmune DiseasesTranslational Research BiomedicalMiceRisk FactorsmedicineAnimalsHumansLack of knowledgeGenetic Predisposition to DiseaseAutoimmune diseaseB-Lymphocytesbusiness.industryGeneral Medicinemedicine.diseaseDisease Models AnimalDisease PresentationImmunologybusinessBiomarkersGenome-Wide Association Study
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