Search results for "rius"

showing 10 items of 278 documents

Ancistrocyclinones A and B, unprecedented pentacyclic N,C-coupled naphthylisoquinoline alkaloids, from the Chinese liana Ancistrocladus tectorius

2018

Two unique pentacyclic N,C-coupled naphthylisoquinolines, the ancistrocyclinones A (5) and B (6), were discovered in the Chinese liana Ancistrocladus tectorius. Furthermore, six known, likewise N,C-coupled alkaloids, viz., ancistrocladinium A (7a) and its mono- and bisphenolic analogs 8a and 9a were isolated, along with their atropo-diastereomers 7b, 8b, and 9b. The stereostructures of 5 and 6 were determined by HRESIMS, 1D and 2D NMR, oxidative degradation, and ECD calculations. The pentacyclic ancistrocyclinones A (5) and B (6) are structurally similar to berberine alkaloids - yet arising from a most different biosynthetic pathway: they are apparently formed by N,C-coupling of their polyk…

Human leukemiaOxidative degradationStereochemistryTumor cellsOxidative phosphorylation010402 general chemistry01 natural sciencesBiochemistryAlkaloidsCell Line TumorHumansPhysical and Theoretical ChemistryCell Proliferationbiology010405 organic chemistryChemistryOrganic ChemistryAncistrocladus tectoriusIsoquinolinesbiology.organism_classificationAntineoplastic Agents PhytogenicCaryophyllalesDrug Resistance Multiple0104 chemical sciencesLianaTwo-dimensional nuclear magnetic resonance spectroscopyBerberine AlkaloidsOrganic and Biomolecular Chemistry
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Tras un denário imitativo de Turiasu hallado en Vila Real (Portugal)

2017

El artículo da a conocer el hallazgo aislado de un importante denario procedente del norte de Portugal. La moneda se caracteriza por ser forrada o falsa de época y por presentar un arte imitativo de Turiasu. También se ofrecen algunas reflexiones y nuevo material numismático en torno a los denarios forrados, imitativos, híbridos e incusos.

Iberian denariusGeographyhybridlcsh:Archaeologylcsh:CC1-960Ancient historycoin platedTuriasuPortugalia: Revista de Arqueologia do Departamento de Ciências e Técnicas do Património da Faculdade de Letras da Universidade do Porto
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Riusi creativi e sezioni complesse: spazi infrastrutturali per il riempimento di relazione

2017

Il saggio affronta una riflessione sulle pratiche della creatività tese a fertilizzare i tessuti urbani in termini di iper-relazionalità sociale, prendendo in considerazione gli assi sopraelevati di attraversamento in disuso, allo scopo di proporre soluzioni di socio-architettura che consentano una rivisitazione in termini slow spaces e favoriscano una riappropriazione vissuta basata su relazioni sociali dense. Da tempo gli spazi aperti di attraversamento sono i luoghi dove si possono sperimentare assetti variabili delineando insieme al disegno delle maglie infrastrutturali nuovi equilibri e nuove configurazioni urbane a percorso lento. Il riuso dei cavalcavia e degli assi sopraelevati sott…

InfrastruttureRiusoCavalcaviaCittà Spazio pubblico Creatività InfrastruttureSettore ICAR/14 - Composizione Architettonica E UrbanaCittà; Spazio Pubblico; Creatività; Infrastrutture.Riuso Spazi pubblici Cavalcavia Sopraelevate Socio-architettura.Spazi pubbliciSopraelevateCreativitàSocio-architetturaCittàSpazio Pubblico
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Preliminary data revealing efficacy of Streptococcus salivarius K12 (SSK12) in Periodic Fever, Aphthous stomatitis, Pharyngitis, and cervical Adeniti…

2023

ObjectiveTo evaluate the potential role of Streptococcus salivarius K12 (SSK12) in controlling febrile flares in patients with Periodic Fever, Aphthous stomatitis, Pharyngitis, and cervical Adenitis (PFAPA) syndrome. Further aims were to assess the impact of SSK12 on (i) flare duration, (ii) variation in the degree of the highest body temperature during flares, (iii) steroid-sparing effect, and (iv) change of PFAPA accompanying symptoms before and after SSK12 introduction.Patients and methodsThe medical charts from 85 pediatric patients with PFAPA syndrome (49 males and 36 females) enrolled in the AIDA registry and treated with SSK12 for a median period of 6.00 ± 7.00 months in the period b…

International Registry PFAPA syndrome Streptococcus salivarius K12 autoinflammatory disease probiotic prophylaxis tonsillitisSettore MED/38 - Pediatria Generale E SpecialisticaAutoinflammationGeneral MedicineHuman medicinePFAPA syndromeFrontiers in Medicine
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The inverse eigenvalue problem for a Hermitian reflexive matrix and the optimization problem

2016

The inverse eigenvalue problem and the associated optimal approximation problem for Hermitian reflexive matrices with respect to a normal {k+1}-potent matrix are considered. First, we study the existence of the solutions of the associated inverse eigenvalue problem and present an explicit form for them. Then, when such a solution exists, an expression for the solution to the corresponding optimal approximation problem is obtained.

Inverse iterationOptimization problemApplied Mathematics010102 general mathematicsMathematical analysisInverseGeneralized inversesEigenvalues010103 numerical & computational mathematicsExpression (computer science)Hermitian matrixMatrius (Matemàtica)01 natural sciencesHermitian matrixComputational MathematicsMatrix (mathematics)Applied mathematics0101 mathematicsDivide-and-conquer eigenvalue algorithmÀlgebra linealOptimization problemMATEMATICA APLICADAEigenvalues and eigenvectorsMathematics
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Characterizations of {K,s+1}-Potent Matrices and Applications

2012

Recently, situations where a matrix coincides with some of its powers have been studied. This kind of matrices is related to the generalized inverse matrices. On the other hand, it is possible to introduce another class of matrices that involve an involutory matrix, generalizing the well-known idempotent matrix, widely useful in many applications. In this paper, we introduce a new kind of matrices called {K,s+1}-potent, as an extension of the aforementioned ones. First, different properties of {K,s+1}-potent matrices have been developed. Later, the main result developed in this paper is the characterization of this kind of matrices from a spectral point of view, in terms of powers of the ma…

Inverse problemsMatrixGroup inverse matrixBlock representationLinear combinationsInvolutory matrixINGENIERIA TELEMATICAMatrius (Matemàtica)Idempotent matrixMatrix algebraSpectrumGroup inverseGeneralized inverseÀlgebra linealMATEMATICA APLICADA
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L'usurpazione di Giovanni: la ricerca della legittimazione, la vittoria sul tyrannus

2020

John’s usurpation: the pursuit of legitimacy, the victory over the tyrannus · In November 423, three months after the death of Honorius, the usurper John was proclaimed em- peror in Rome. He had been primicerius notariorum at the court of Ravenna and his elevation was made by the members of the aulé, as Procopius reports. Neverthless, the sources are not agreed: Malala says that John was a synkletikoi and ruled supported by the synkletikoi The literary and numismatic evidence shows that John aspired to recognition as lawful sovereign in the two parts of the Empire. Theodosius restored order and legitimacy to the West with the military intervention and the proclamation of Valentinian III as…

John Usurper Honorius Theodosius Galla Placidia Valentinian III Aetius OlympiodorusSettore L-ANT/03 - Storia Romana
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385 MOLECULAR STAGES OF PDGFB DRIVEN LIVER FIBROSIS: LESONS FROM A TRANSGENIC MOUSE MODEL

2012

underlying pathomechanisms is hampered by the lack of a suitable animal model. To circumvent this problem, we studied hepcidinknockout (KO) mice as a model of iron-overload associated liver disease. Methods: 6 and 12 month-old hepcidin-KO and -wild type (WT) mice fed 3% iron carbonyl-containing diet (Fe-diet) since four weeks of age were compared to age-matched WT and KO animals kept on standard diet. The liver phenotype was quantified serologically as well as morphometrically based on hematoxylin & eosin, Prussian blue and Sirius red stainings. Liver iron content was determined by atomic mass absorption. Liver fibrosis development was determined by collagen RT-PCR and hydroxyproline assay.…

Liver injuryPathologymedicine.medical_specialtyHepatologymedicine.diagnostic_testbiologyH&E stainmedicine.diseaseHepatic stellate cell activationHydroxyprolinechemistry.chemical_compoundLiver diseaseEndocrinologychemistryHepcidinInternal medicineSerum ironmedicinebiology.proteinSirius RedJournal of Hepatology
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Data from: A link between heritable parasite resistance and mate choice in dung beetles

2019

Parasites play a central role in the adaptiveness of sexual reproduction. Sexual selection theory suggests a role for parasite resistance in the context of mate choice, but the evidence is mixed. The parasite-mediated sexual selection (PMSS) hypothesis derives a number of predictions, among which that resistance to parasites is heritable, and that female choice favours parasite resistance genes in males. Here we tested the PMSS hypothesis using the dung beetle Onthophagus taurus, a species that can be heavily parasitised by Macrocheles merdarius mites, which are known to affect adult survival. We investigated the heritability of resistance to M. merdarius, as well as whether female O. tauru…

MacrochelesOnthophagusintegumentary systemOnthophagus taurusectoparasitismparasitic diseasesMacrocheles merdarius
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Scientific Reports

2020

.-- Halimubieke, Naerhulan et al.

Male0106 biological sciences0301 basic medicineEvolutionQH301 Biologylcsh:MedicineBreedingeläinten käyttäytyminen010603 evolutionary biology01 natural sciencesArticlekurmitsatCharadriiformesSexual Behavior AnimalQH30103 medical and health sciencesNestDivorceAnimalsMatinglcsh:ScienceAuthor CorrectionEvolutionary theorypesintäPair BondQLMultidisciplinarylisääntymiskäyttäytyminenEcologybiologyReproductive successReproductionPloverlcsh:RDASQL Zoologybiology.organism_classificationBiological EvolutionCharadriusPair bondBreed030104 developmental biologylinnutlcsh:QFemalepariutuminenZoologyDemography
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