Search results for "road"
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Memorands jaunbūvējamās dzelzceļu līnijas Rīga-Ērgļi-Kārsava posma Ērgļi-Madona lietā
1934
Mašīnraksta kopija
Strategies to gain novel Alzheimer’s disease diagnostics and therapeutics using modulators of ABCA transporters
2021
Adenosine-triphosphate-(ATP)-binding cassette (ABC) transport proteins are ubiquitously present membrane-bound efflux pumps that distribute endo- and xenobiotics across intra- and intercellular barriers. Discovered over 40 years ago, ABC transporters have been identified as key players in various human diseases, such as multidrug-resistant cancer and atherosclerosis, but also neurodegenerative diseases, such as Alzheimer���s disease (AD). Most prominent and well-studied are ABCB1, ABCC1, and ABCG2, not only due to their contribution to the multidrug resistance (MDR) phenotype in cancer, but also due to their contribution to AD. However, our understanding of other ABC transporters is limited…
Forest Road Planning, Construction and Maintenance to Improve Forest Fire Fighting: a Review
2019
Forest roads play a key-role in fire fighting activities. In fact, all ground-based activities are strictly related to the presence of forest roads as access to fire edge. In spite of this important role, forest roads are often planned and built without considering their use in fire fighting, and this also occurs in literature, where few studies are dedicated to the importance of forest roads in fire fighting. A well-developed and well-maintained forest road network is the answer to different needs in fire management. The objective of this review is to clarify basic principles for obtaining efficient road network also for fire fighting, collecting, defining and resuming the main roles, the …
Mobile Phone Data Statistics as Proxy Indicator for Regional Economic Activity Assessment
2019
The mobile data analysis is an authoritative source of information for problems solving in the fields of human activity recognition, population dynamics, tourism, transport planning, traffics measuring, public administration and other activities and could be the source for valuable information as a proxy indicator. One of the obstacles to user data from mobile operators is compliance to the General Data Protection Regulation, so the development of data analytics approach that protects personal data without a necessity to identify mobility of particular persons was developed, that still provides economically relevant data. In the present research, the method for the economic activity assessm…
Motor Vehicles Not Used in Road Traffic Are Also Subject to Compulsory Insurance in Europe - CJEU Clarification in Case C-80/17
2019
The article analyses a recent significant case in the Court of Justice of the European Union on the extent of compulsory insurance in the field of motor insurance. The judgment delivered by the Grand Chamber of the CJEU on 04 September 2018 clarifies the obligation to conclude a motor insurance contract in a situation when a motor vehicle is no longer intended to be used in road traffic. If previously there was no doubt that motor vehicles that are used in road traffic are subject to compulsory insurance, it was unclear whether compulsory insurance in the field of motor insurance also extends to vehicles which are no longer intended to be used in road traffic. The Court formulated the ‘thre…
OXA-163-Producing Klebsiella pneumoniae in Cairo, Egypt, in 2009 and 2010
2012
ABSTRACT Two genetically unrelated OXA-163-carrying Klebsiella pneumoniae strains were identified from two infection cases in June 2009 and May 2010 in Cairo, Egypt. OXA-163-producing Enterobacteriaceae had been previously reported in Argentina only. Both patients had no history of travel abroad. The emergence of this newly recognized OXA-48-related β-lactamase able to hydrolyze cephalosporins and carbapenems is especially worrying in a geographic area where OXA-48 is endemic and effective surveillance for antibiotic resistance is largely unaffordable.
Patients' and therapists' experiences of general change mechanisms during bug-in-the-eye and delayed video-based supervised cognitive-behavioral ther…
2016
Objective This secondary analysis of a randomized controlled trial investigated whether bug-in-the-eye (BITE) supervision (live computer-based supervision during a psychotherapy session) affects the manner in which patients and therapists experience general change mechanisms (GCMs) during cognitive-behavioral therapy (CBT). Method A total of 23 therapists were randomized either to the BITE condition or the control condition (delayed video-based [DVB] supervision). After each session, both patients (BITE: n = 19; DVB: n = 23) and therapists (BITE: n = 11; DVB: n = 12) completed the Helping Alliance Questionnaire (HAQ) and the Bernese Post Session Report (BPSR). The HAQ total score and the 3 …
The age-related performance decline in ultraendurance mountain biking
2013
Haupt, Samuel | Knechtle, Beat | Knechtle, Patrizia | Ruest, Christoph Alexander | Rosemann, Thomas | Lepers, Romuald; International audience; ''The age-related changes in ultraendurance performance have been previously examined for running and triathlon but not mountain biking. The aims of this study were (i) to describe the performance trends and (ii) to analyze the age-related performance decline in ultraendurance mountain biking in a 120-km ultraendurance mountain bike race the Swiss Bike Masters from 1995 to 2009 in 9,325 male athletes. The mean (+/- SD) race time decreased from 590 +/- 80 min to 529 +/- 88 min for overall finishers and from 415 +/- 8 min to 359 +/- 16 min for the top …
Driving under the influence of alcohol: frequency, reasons, perceived risk and punishment
2015
Background The aim of this study was to gain information useful to improve traffic safety, concerning the following aspects for DUI (Driving Under the Influence): frequency, reasons, perceived risk, drivers' knowledge of the related penalties, perceived likelihood of being punished, drivers’ perception of the harshness of punitive measures and drivers’ perception of the probability of behavioral change after punishment for DUI. Methods A sample of 1100 Spanish drivers, 678 men and 422 women aged from 14 to 65 years old, took part in a telephone survey using a questionnaire to gather sociodemographic and psychosocial information about drivers, as well as information on enforcement, clustered…
The link between mitochondrial DNA hypervariable segment I heteroplasmy and ageing among genetically unrelated Latvians
2011
International audience; Various studies have demonstrated that mitochondrial DNA (mtDNA) heteroplasmy tends to increase with age and that the observed frequency of heteroplasmy among populations mostly depends on the way it is measured. Therefore, we investigated age-related association on the presence of mtDNA heteroplasmy within the hypervariable segment 1 (HVS-I) in a selected study group. The study group consisted of 300 maternally unrelated Latvians ranging in age from 18 to over 90years. To determine the optimal method for mtDNA heteroplasmy detection, three approaches were used: (i) SURVEYORTM Mutation Detection Kit, (ii) sequencing and (iii) denaturing gradient-gel electrophoresis (…