Search results for "s disease"

showing 10 items of 5637 documents

A case of guillain-barre syndrome in a patient with non small cell lung cancer treated with chemotherapy

2006

Guillain-Barré Syndrome (GBS) is a demyelinating polyneuropathy of probable autoimmune pathogenesis characterized by rapidly progressive symmetric paralysis. In the literature some cases of GBS associated with anticancer chemotherapy are reported. We present a case of a 55-year old woman who complained of progressive motor deficit in four limbs, areflexia in lower limbs and facial nerve paralysis one week after beginning cisplatin-gemcitabine chemotherapy for metastatic lung cancer. The cerebrospinal fluid analysis showed a strong positive Pandy reaction with 435 mg/dl total protein. The electromyography and the electroneuronography established the diagnosis of inflammatory demyelinating po…

medicine.medical_specialtyLung Neoplasmsmedicine.medical_treatmentBone NeoplasmsGuillain-Barre SyndromeDeoxycytidineGastroenterologyPathogenesisCerebrospinal fluidCarcinoma Non-Small-Cell LungInternal medicineAntineoplastic Combined Chemotherapy ProtocolsElectroneuronographyParalysismedicineHumansPharmacology (medical)Lung cancerPharmacologyChemotherapyGuillain-Barre syndromebusiness.industryGuillain-Barré Syndrome neuropathy chemotherapy toxicity lung cancerImmunoglobulins IntravenousMiddle Agedmedicine.diseaseGemcitabineFacial nerveSurgeryInfectious DiseasesOncologyFemaleCisplatinmedicine.symptombusiness
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Effects of 1-(halogenalkoxy)alkyl-5-fluorouracil derivatives on cell growth, cell volume and nucleus size of mouse lymphoma cells.

1992

The effects of three 1-(halogenalkoxy)alkyl-5-fluorouracil derivatives on cultured mouse lymphoma cells were studied and compared with those of N-methyl-bis-(2-chloroethyl)amine hydrochloride (Lost). The derivatives exert only little influence on cell proliferation and cell volume. However, all derivatives cause a concentration-dependent nucleus contraction, probably due to DNA cross-linkings. Bromodesoxyuridine modulates the effects of the derivatives on the DNA, leading to swelling of the nucleus, which may be caused by DNA strand-breaks. It is suggested that the derivatives exert synergistic effects with other factors. It is concluded that these studies are suitable for the prescreening …

medicine.medical_specialtyLymphomaHydrochlorideDNA damageBiologychemistry.chemical_compoundMiceInternal medicineDrug DiscoverymedicineTumor Cells CulturedAnimalsPharmacology (medical)PharmacologyCell NucleusCell growthBiological activityGeneral Medicinemedicine.diseaseMolecular biologyIn vitroLymphomaInfectious Diseasesmedicine.anatomical_structureEndocrinologyOncologychemistryFluorouracilNucleusDNACell DivisionChemotherapy
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Assessment of etanercept efficacy in the treatment of psoriatic arthritis: ultrasonography of Achilles tendon

2015

medicine.medical_specialtyMEDLINEArthritisDermatologyAchilles TendonEtanerceptEtanercept030207 dermatology & venereal diseases03 medical and health sciencesPsoriatic arthritis0302 clinical medicinemedicineHumansUltrasonography030203 arthritis & rheumatologyAchilles tendonbusiness.industryArthritis Psoriaticmedicine.diseaseDermatologymedicine.anatomical_structureInfectious DiseasesUltrasonographybusinessmedicine.drugHuman2708
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Meta-analysis of the placebo rates of clinical relapse and severe endoscopic recurrence in post-operative Crohn's disease

2008

Meta-analysis of the placebo rates of clinical relapse and severe endoscopic recurrence in postoperative Crohn's disease. Renna S, Cammà C, Modesto I, Cabibbo G, Scimeca D, Civitavecchia G, Mocciaro F, Orlando A, Enea M, Cottone M. Dipartimento di Medicina, Pneumologia e Fisiologia della Nutrizione Umana, Università di Palermo, Palermo, Italy. BACKGROUNDS & AIMS: The benefit of therapy for prevention of postoperative recurrence of Crohn's disease (CD) is limited. Clinical relapse and severe endoscopic recurrence are the main outcomes in the evaluation of trials on prevention of recurrence. The aim of this meta-analysis was to focus on knowledge of the placebo rates of relapse and recurr…

medicine.medical_specialtyMEDLINEDiseasePlaceboEndoscopy Gastrointestinallaw.inventionCrohn DiseaseRandomized controlled triallawInternal medicineSecondary PreventionmedicineHumansPostoperative PeriodDigestive System Surgical ProceduresRandomized Controlled Trials as TopicCrohn's diseaseHepatologybusiness.industryGastroenterologyOdds ratioPrognosismedicine.diseaseConfidence intervalSurgeryMeta-analysisMeta-analysis placebo relapse severe endoscopic recurrencebusiness
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The Management of Dental Practices in the Post-COVID 19 Era: An Economic and Operational Perspective

2020

Background: In order to protect dental teams and their patients during the COVID-19 pandemic, dentists have had to adopt several measures (operating and post-operating procedures) which may increase the total treatment time and costs relating to individual protective measures. This paper will propose a thorough analysis of operating dentistry procedures, comparing the economic performance of the activity in a dental surgery before and after the adoption of these protective measures, which are required to contain the risk of SARS-COV-2 infections. Methods: The economic analysis is articulated in three approaches. Firstly, it assesses a reduction in markup by maintaining current charges (A)

medicine.medical_specialtyMarkup language010504 meteorology & atmospheric sciencesCoronavirus disease 2019 (COVID-19)Health Toxicology and Mutagenesislcsh:Medicine01 natural sciencesArticle03 medical and health sciences0302 clinical medicineOrder (exchange)medicineEconomic analysisHumansOperations managementEconomic impact analysisPandemicsEconomic consequences0105 earth and related environmental sciencesInfection ControldentistrySARS-CoV-2Perspective (graphical)lcsh:REconomics DentalPublic Health Environmental and Occupational HealthCOVID-19030206 dentistryeconomicsDental surgeryBusinessmanagement
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Japanese, Mediterranean and Argentinean diets and their potential roles in neurodegenerative diseases

2019

Environmental factors are responsible of cellular senescence and processes found in the development of cognitive disorders. The aim of this paper is to compare benefits of the Japanese, Mediterranean, and Argentinian Diet on the onset or prevention of senile dementia (SD) and Alzheimer's Disease (AD). Special focus was on the effects of specific compounds such as polyunsaturated fatty acids (PUFAs), antioxidants, and saturated and trans fatty acids. A high adherence to diets rich in PUFAs, monounsaturated fatty acids (MUFAs) and antioxidants may decrease the risk of developing neurodegenerative diseases ; while the predominance of saturated and trans fatty acids possibly rises it.

medicine.medical_specialtyMediterranean diet030309 nutrition & dieteticsArgentinaCellular senescenceDiseaseBiologySenile dementiaDiet MediterraneanNeuroprotection03 medical and health sciences0404 agricultural biotechnologyJapanAlzheimer DiseaseInternal medicinealzheimer's disease ; neuroprotection ; mediterranean diet ; japanese style diet ; food patternmedicineHumanschemistry.chemical_classification0303 health sciencesMediterranean RegionNeurodegenerative Diseases04 agricultural and veterinary sciences040401 food scienceNeuroprotectionDietEndocrinologychemistryFatty Acids UnsaturatedDementiaFood SciencePolyunsaturated fatty acidFood Research International
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Neurotropism in newborn hamsters of plaque purified measles virus clones

1976

Three plaque purified measles virus clones displayed a different neurotropism in newborn hamsters.

medicine.medical_specialtyMesocricetusVirulencebiologyvirusesNeurotropismBrainGenetic VariationGeneral MedicineVirus Replicationbiology.organism_classificationVirologyCell LineMeasles virusMedical microbiologyAnimals NewbornCytopathogenic Effect ViralMeasles virusViral releaseInfectious disease (medical specialty)CricetinaeVirologymedicineAnimalsArchives of Virology
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2019

OBJECTIVE With a combination of different sympathetic tests, we aimed to elucidate whether impairment of sympathetic function in Parkinson's disease (PD) is the consequence of a central or peripheral efferent dysfunction. METHODS Thirty-five patients with early-to-intermediate PD (median age: 63 years; IQR: 57-67 years; disease duration 1-9 years, 15 women) and 20 age- and sex-matched healthy controls (median age: 64.5 years; IQR: 58-68 years; 10 women) were recruited. Autonomic testing was performed in two subgroups and included the assessment of resting cardiovascular parameters, postprandial hypotension (PPH), orthostatic hypotension (OH), and vasoconstriction induced by intradermal micr…

medicine.medical_specialtyMicrodialysisParkinson's diseasebusiness.industry05 social sciencesMicroneurographymedicine.disease050105 experimental psychology03 medical and health sciencesBehavioral NeuroscienceOrthostatic vital signsNorepinephrine0302 clinical medicineBlood pressureInternal medicinemedicineCardiology0501 psychology and cognitive sciencesmedicine.symptomPure autonomic failurebusiness030217 neurology & neurosurgeryVasoconstrictionmedicine.drugBrain and Behavior
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Stay Home, Stay Active with SuperJump®: A Home-Based Activity to Prevent Sedentary Lifestyle during COVID-19 Outbreak

2020

The purpose of this study was to investigate the intensity of SuperJump® workout as a home-based activity for fulfilling physical activity recommendations during COVID-19 home-confinement. Seventeen (males: n = 10; females: n = 7) college students (age: 25.8 ± 2.7 years; height: 1.7 ± 0.1 m; weight: 66.2 ± 12.1 kg) participated in the study. To assess the intensity of the activity (30-min), heart rate (HR), expressed as percentages of age-predicted maximal HR (%HRmax), and session ratings of perceived exertion (sRPE), collected on a CR10 scale, were used. %HRmax data were categorically separated in five classes of intensity according to the American College of Sport…

medicine.medical_specialtyMini-trampolineCoronavirus disease 2019 (COVID-19)Geography Planning and DevelopmentHeart rateTJ807-830Perceived exertionManagement Monitoring Policy and LawTD194-195Renewable energy sources03 medical and health sciences0302 clinical medicineHeart ratehome training; coronavirus; exercise; heart rate; mini-trampoline; rate of perceived exertionmedicineGE1-350030212 general & internal medicineExerciseSedentary lifestyleEnvironmental effects of industries and plantsRenewable Energy Sustainability and the Environmentbusiness.industryHome trainingRate of perceived exertionRepeated measures design030229 sport sciencesHome basedIntensity (physics)Environmental sciencesCoronavirusCoronavirus; Exercise; Heart rate; Home training; Mini-trampoline; Rate of perceived exertionPhysical therapyExercise intensitybusinesshuman activitiesSustainability; Volume 12; Issue 23; Pages: 10135
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Use of drug treatments for Alzheimer's disease in France: a study on a national level based on the National Alzheimer's Data Bank (Banque Nationale A…

2012

Purpose To examine the way in which specific drug treatments for Alzheimer's disease are used and whether their use complies with clinical practice guidelines issued by the French National Authority for Health in patients with Alzheimer's disease. Methods We analysed a cross-section of the French National Alzheimer's databank (BNA). Participants were individuals who consulted centres contributing to the BNA in 2010 and diagnosed with Alzheimer's disease and with at least one Mini Mental State Examination (MMSE) score recorded during the course of the year. Results Of 191 919 consultations recorded in the database, 29.9% involved a diagnosis of Alzheimer's disease, and 26 809 patients had co…

medicine.medical_specialtyMini–Mental State Examinationmedicine.diagnostic_testEpidemiologyCross-sectional studybusiness.industrymedicine.drug_classMemantineDiseasePharmacoepidemiologymedicine.diseaseAcetylcholinesterase inhibitorInternal medicinemedicinePharmacology (medical)Alzheimer's diseaseMedical prescriptionPsychiatrybusinessmedicine.drugPharmacoepidemiology and Drug Safety
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