Search results for "sequence"

showing 10 items of 4987 documents

Genome-wide association study and mouse expression data identify a highly conserved 32 kb intergenic region between WNT3 and WNT9b as possible suscep…

2014

Item does not contain fulltext Bladder exstrophy-epispadias complex (BEEC), the severe end of the urorectal malformation spectrum, has a profound impact on continence as well as sexual and renal functions. It is widely accepted that for the majority of cases the genetic basis appears to be multifactorial. Here, we report the first study which utilizes genome-wide association methods to analyze a cohort comprising patients presenting the most common BEEC form, classic bladder exstrophy (CBE), to identify common variation associated with risk for isolated CBE. We employed discovery and follow-up samples comprising 218 cases/865 controls and 78 trios in total, all of European descent. Our disc…

genetics [Wnt3 Protein]Genome-wide association studyGenomeConserved sequenceMiceIntergenic regionMedizinische FakultätSALL1 protein humanGenetics (clinical)Conserved SequenceGeneticsgenetics [Wnt Proteins]Association Studies ArticlesGeneral Medicinegenetics [Transcription Factors]genetics [European Continental Ancestry Group]WNT3 protein humanReconstructive and regenerative medicine Radboud Institute for Molecular Life Sciences [Radboudumc 10]metabolism [Wnt3 Protein]Medical geneticsmedicine.medical_specialtygenetics [White People]WNT9B protein human-BiologyPolymorphism Single NucleotideWhite Peopleembryology [Genitalia]Wnt3 Proteinpathology [Bladder Exstrophy]metabolism [Wnt Proteins]genetics [Bladder Exstrophy]ddc:570GeneticsmedicineAnimalsHumansGenetic Predisposition to Diseaseddc:610GenitaliaMolecular BiologyGeneBase SequenceBladder ExstrophyCase-control studymedicine.diseasemetabolism [Genitalia]Bladder exstrophyWnt ProteinsReconstructive and regenerative medicine Radboud Institute for Health Sciences [Radboudumc 10]Case-Control StudiesGenome-Wide Association StudyTranscription Factors
researchProduct

In vitro evolution of an atrazine-degrading population under cyanuric acid selection pressure: Evidence for the selective loss of a 47kb region on th…

2011

International audience; The adaptation of microorganisms to pesticide biodegradation relies on the recruitment of catabolic genes by horizontal gene transfer and homologous recombination mediated by insertion sequences (IS). This environment-friendly function is maintained in the degrading population but it has a cost which could diminish its fitness. The loss of genes in the course of evolution being a major mechanism of ecological specialization, we mimicked evolution in vitro by sub-culturing the atrazine-degrading Pseudomonas sp. ADP in a liquid medium containing cyanuric acid as the sole source of nitrogen. After 120 generations, a new population evolved, which replaced the original on…

genetics and hereditypseudomonas sp adp[SDV]Life Sciences [q-bio]PopulationAdaptation BiologicaladaptationBiology03 medical and health sciencesPlasmidMolecular evolutionPseudomonasGene duplicationGeneticsDirect repeatexperimental evolutionSelection GeneticInsertion sequenceHomologous RecombinationeducationGeneComputingMilieux_MISCELLANEOUS030304 developmental biology2. Zero hungerGenetics0303 health scienceseducation.field_of_studygenetic plasticitymolecular evolutionHerbicidesTriazines030306 microbiologycyanuric acidGeneral MedicineBiological EvolutionGenes Bacterial[SDE]Environmental SciencesAtrazineHomologous recombinationGene Deletion
researchProduct

The influence of backslopping on lactic acid bacteria diversity in tarhana fermentation

2020

Tarhana is produced at batch systems in which the microbiota has changed accordingly to the microbial load from ingredients. In order to stabilize the microbiota, the effects of backslopping carried out under different temperature regimes (25 and 30 °C), pH (3.70 and 4.00) and inoculation rates (5, 10 and 15%) on lactic acid bacteria (LAB) diversity were determined in tarhana dough. LAB and Total Aerobic Mesophilic Bacteria (TAMB) numbers increased in all tarhana dough samples subjected to backslopping. Temperature and pH significantly affected the microbiological diversity of tarhana whereas the different inoculation rates did not. Tarhana dough showed complex tarhana microbiota following …

genomic DNAtomatochemistry.chemical_compoundCereal fermentationpepperLactobacillalesLactococcusFermented Foods and BeveragesLactic acid bacteriageneticsFood scienceyoghurtfermentationonionbiodiversity0303 health sciencesbiologyLactobacillus brevisBacksloppingpHMicrobiotaTemperaturefermented productGeneral MedicineBreadHydrogen-Ion ConcentrationLactobacillus brevisLactic acidStarter cultureclassificationBatch Cell Culture TechniquesTarhana microbiotasodium chlorideFermented Foodsmicrobial communityMesophilelactic acid bacteriumRNA 16Sgene sequenceArticlewheat flour03 medical and health sciencesinoculationproceduresacidity030304 developmental biologydoughnonhuman030306 microbiologyisolation and purificationmicrobiologyStreptococcusbiology.organism_classificationLactobacilluschemistrymicrobial diversityWeissellaCarnobacteriumFermentationpolymerase chain reaction denaturing gradient gel electrophoresismicrofloraLactobacillus alimentariusbatch cell culturemetabolismLactobacillus alimentariusLactobacillus plantarumBacteriaEnterococcusLeuconostocSettore AGR/16 - Microbiologia AgrariaFood ScienceLactobacillus plantarum
researchProduct

Predicting the potential global range of common ragweed (Ambrosia artemisiifolia) using biologically informed and correlative species distribution mo…

2012

National audience

geographical origin[SDV.BA] Life Sciences [q-bio]/Animal biologybotanical gardenunique vector[SDV.BA]Life Sciences [q-bio]/Animal biologyconsequence[SDE.BE] Environmental Sciences/Biodiversity and EcologyEurope[SDV.BDD] Life Sciences [q-bio]/Development Biologyinvasion of ragweed[SDE.BE]Environmental Sciences/Biodiversity and Ecology[SDV.BDD]Life Sciences [q-bio]/Development BiologyComputingMilieux_MISCELLANEOUSAmbrosia artemisiifolia
researchProduct

An unbounded family of log Calabi–Yau pairs

2016

We give an explicit example of log Calabi-Yau pairs that are log canonical and have a linearly decreasing Euler characteristic. This is constructed in terms of a degree two covering of a sequence of blow ups of three dimensional projective bundles over the Segre-Hirzebruch surfaces ${\mathbb F}_n$ for every positive integer $n$ big enough.

geography of threefoldSequenceDegree (graph theory)Projective bundleGeneral Mathematics14J30 14J32 14J60CombinatoricsMathematics - Algebraic Geometrysymbols.namesakeMathematics::Algebraic Geometryprojective bundlesIntegerEuler characteristicLog Calabi-Yau pairFOS: MathematicssymbolsCalabi–Yau manifoldSettore MAT/03 - GeometriaAlgebraic Geometry (math.AG)Mathematics::Symplectic GeometryMAT/03 - GEOMETRIAMathematicsRendiconti Lincei - Matematica e Applicazioni
researchProduct

Plio-Pleistocene geological evolution of the northern Sicily continental margin (southern Tyrrhenian Sea): new insights from high-resolution, multi-e…

2003

High-resolution seismic profiles were acquired in the north Sicily offshore region with an innovative, multi-tip sparker array which lacks ringing and has a base frequency around 600 Hz. The new data, combined with published data, suggest that intra-slope and extensional basins formed as a consequence of the late Miocene (?)–early Pliocene shortening and thrusting, and the middle (?)–late Pliocene continental rifting affecting the internal side of the Sicilian-Maghrebian chain. Early (?) Pleistocene to Holocene high-amplitude and high-frequency sea-level changes resulted in repeated sub-aerial exposure and flooding of the shelf, and the deposition of cyclically arranged hemipelagic and shel…

geographyRiftgeography.geographical_feature_categoryHigh-resolution seismic profilePleistoceneSettore GEO/02 - Geologia Stratigrafica E SedimentologicaContinental shelfNorth Sicily offshoreSequence StratigraphyPlio-PleistoceneEnvironmental Science (miscellaneous)Late MioceneGeotechnical Engineering and Engineering GeologyOceanographyNorth Sicily offshore; High-resolution seismic profiles; Cefalù basin; Sequence StratigraphyPaleontologyContinental marginCefalù basinEarth and Planetary Sciences (miscellaneous)TransgressiveGeologyHolocene
researchProduct

1993

The miocene deposits of the Quesa basin (Betic foreland) outcrops in the central part of the Valencia province (Spain). Quesa basin is a subsiding hanging-wall basin related to an ENE-WSW listric fault system. The deposits of this basin are formed by a 440 metres thick sequence of red clays, containing few intercalations of sandstones and micritic white limestones, and breccias. The upper 70 metres of this sequence is a wedge-shaped unit composed by breccias containing megablocks, wich interfinger with tabular limestones towards the central part of the basin. The breccias are foot-wall derived debris fiow deposits formed during normal faulting. A mammal site close to the base of the breccia…

geographyTectonicsSequence (geology)geography.geographical_feature_categoryOutcropBrecciaGeochemistryGeologyStructural basinFault (geology)DebrisForeland basinGeologyEstudios Geológicos
researchProduct

Stratigraphy of the Neoproterozoic Damara Sequence in northwest Namibia: Slope to basin sub-marine mass-transport deposits and olistolith fields

2016

Abstract The Neoproterozoic Damara Sequence (>1000 m thick) is composed of siliciclastic and carbonate rocks that crop out in the Damara Belt, Namibia. In Damaraland (including the Vrede, Bethanis, Austerlitz and Toekoms farms), these rocks were deformed and metamorphosed under greenschist facies (biotite zone) conditions during the Damara Orogeny. The stratigraphy and paleoenvironments of the Damara Sequence rocks are debated by the scientific community. We use field data, including detailed 1:25,000 geological mapping, elaboration of stratigraphic profiles and observation of preserved primary structures, textures and composition, to identify lithofacies and lithofacies associations, and t…

geographygeography.geographical_feature_category010504 meteorology & atmospheric sciencesAlluvial fanGeology010502 geochemistry & geophysics01 natural sciencesUnconformityOnlapPaleontologySequence (geology)Basement (geology)Geochemistry and PetrologyCarbonate rockThrust faultSiliciclasticGeology0105 earth and related environmental sciencesPrecambrian Research
researchProduct

Stratigraphy, geochemistry and geochronology of a Quaternary pyroclastic sequence of the Chichontepec volcano, El Salvador

2013

In this paper we present sedimentological, chemical and geochronological data on a pyroclasticsequence deposited at Chichontepeque Volcano (El Salvador) during a caldera-forming Plinian phase.Granulometric analyses and width distribution patterns of airfall pyroclastics showed that these are the result ofat least two eruptions, the oldest being the more complete. The Basal Fall, which marks the beginning of thePlinian eruption, shows the typical features of Plinian air-fall deposits.Chemical trends mirror roughly a downward tapping from a zoned magma chamber; inside each fall unit crys-tal fractionation trends can be recognized. 39Ar/40Ar dating of lavas underlying and overlying the pyrocla…

geographygeography.geographical_feature_categoryGeochemistryPyroclastic rockGeneral MedicineMagma chamberBefore PresentSequence (geology)VolcanoStratigraphy550 Earth sciences & geologyGeochronologyQuaternary550 Earth sciences & geologyGeologyRevista Geológica de América Central
researchProduct

Vertical movements in NE Sicily and its offshore: Outcome of tectonic uplift during the last 125 ky

2013

New data in the coastal area between Acquedolci and Patti (northeastern Sicily, Italy) have been collected to calculate vertical tectonic rates in a key sector between the Kabilian-Calabrian and the Sicilian-Maghrebian chain. The comparison among marine geology data (multibeam and seismic reflection profiles) on the continental shelf-slope system and the radiocarbon ages on geomorphological markers collected during a coastal survey, provided new stratigraphic, geomorphological and biological data, contributing to the knowledge of the geological evolution of this sector for the last 125 ky.This coastal area is framed between two main structural features active during the Pleistocene in north…

geographygeography.geographical_feature_categoryPleistoceneHoloceneLast Glacial MaximumSettore GEO/02 - Geologia Stratigrafica E SedimentologicaSettore GEO/03 - Geologia StrutturaleSettore GEO/04 - Geografia Fisica E GeomorfologiaMarine geologyLast Glacial MaximumFault (geology)Last Interglaciallaw.inventionTectonicsTectonic upliftlawRelative Sea level changeUplift rateLate Quaternary depositional sequenceRadiocarbon datingGeomorphologyGeologyHoloceneEarth-Surface Processes
researchProduct