Search results for "severity"

showing 10 items of 1287 documents

Disability, and not diabetes, is a strong predictor of mortality in oldest old patients hospitalized with pneumonia

2018

Abstract Background Pneumonia causes more deaths than any other infectious disease, especially in older patients with multiple chronic diseases. Recent studies identified a low functional status as prognostic factor for mortality in elderly patients with pneumonia while contrasting data are available about the role of diabetes. The aim of this study was to evaluate the in-hospital, 3-month and 1-year mortality in elderly subjects affected by pneumonia enrolled in the RePoSi register. Methods We retrospectively analyzed the data collected on hospitalized elderly patients in the frame of the REPOSI project. We analyzed the socio-demographic, laboratory and clinical characteristics of subjects…

Malemedicine.medical_specialtyMultivariate analysisBarthel indexSocio-culturaleComorbidity030204 cardiovascular system & hematologyDiabeteSeverity of Illness IndexComorbidity; Diabetes; Disability; Elderly; Pneumonia; Aged; Aged 80 and over; Comorbidity; Diabetes Mellitus; Disabled Persons; Female; Geriatric Assessment; Hospitalization; Humans; Italy; Logistic Models; Male; Multivariate Analysis; Pneumonia; Retrospective Studies; Risk Factors; Severity of Illness Index03 medical and health sciences0302 clinical medicineElderlyRisk FactorsDiabetes mellitusInternal medicineSeverity of illnessmedicine80 and overDiabetes MellitusInternal MedicineHumansDisabled Persons030212 general & internal medicineGeriatric AssessmentAgedRetrospective StudiesAged 80 and overDisabilitybusiness.industrySettore MED/09 - MEDICINA INTERNADiabetesRetrospective cohort studyOdds ratioPneumoniamedicine.diseaseOldest oldComorbidityPneumonia; Elderly; Disability; Diabetes; ComorbidityHospitalizationLogistic ModelsItalyMultivariate AnalysisFemaleComorbidity Diabetes Disability Elderly Pneumoniabusiness
researchProduct

Mannheim Peritonitis Index (MPI) and elderly population: prognostic evaluation in acute secondary peritonitis

2016

Introduction. Acute Secondary Peritonitis due to abdominal visceral perforation is characterized by high mortality and morbidity risk. Risk stratification allows prognosis prediction to adopt the best surgical treatment and clinical care support therapy. In Western countries elderly people represent a significant percentage of population Aim. Evaluation of Mannheim Peritonitis Index (MPI) and consideration upon old people. Patients and methods. Retrospective study on 104 patients admitted and operated for “Acute Secondary Peritonitis due to visceral perforation”. MPI was scored. In our study we want to demonstrate efficacy of MPI and the possibility to consider older age an independent …

Malemedicine.medical_specialtyMultivariate analysisPrognosiPerforation (oil well)PopulationPeritonitisPeritonitis030230 surgeryLower riskSeverity of Illness IndexScore system03 medical and health sciencesElderly0302 clinical medicineInternal medicineSeverity of illnessmedicineHumansMortalityEvaluationeducationAgedRetrospective StudiesAcute secondary peritonitiAged 80 and overAcute secondary peritonitis; Elderly; Evaluation; High mortality risk; Mannheim Peritonitis Index (MPI); Mortality; Perforative peritonitis; Prognosis; Score systems; SurgeryMannheim Peritonitis Index (MPI)education.field_of_studyPerforative peritonitibusiness.industryMortality rateRetrospective cohort studyMiddle AgedPrognosismedicine.diseaseSurgeryHigh mortality riskIntestinal PerforationAcute DiseaseOriginal ArticleFemaleSurgery030211 gastroenterology & hepatologybusinessGiornale di Chirurgia - Journal of Surgery
researchProduct

Smoking Status and Severity of Ischemic Stroke. A Population-Based Study

2013

We aimed to investigate the impact of smoking status on clinical severity in patients with ischemic stroke event (IS). Patients were prospectively identified among residents of the city of Dijon, France (ca. 151,000 inhabitants), using a population-based registry, between 2006 and 2011. Demographic and clinical data were recorded. The initial clinical severity was quantified by the means of the National Institutes of Health Stroke Scale (NIHSS). Multivariable ordinal logistic regression was used to assess the effect of smoking status on severity. Among the 1,056 recorded patients with IS, data about smoking status were available for 973 (92.1%), of whom 658 (67.3%) were non-smokers, 187 (19…

Malemedicine.medical_specialtyMultivariate analysismedicine.medical_treatmentPopulationSeverity of Illness IndexBrain IschemiaInternal medicineEpidemiologySeverity of illnessmedicineHumansProspective StudiesRegistrieseducationProspective cohort studyAgededucation.field_of_studybusiness.industrySmokingMiddle AgedFormer SmokerStrokeLogistic ModelsNeurologyMultivariate AnalysisPhysical therapySmoking cessationFemaleSmoking CessationFranceNeurology (clinical)Ordered logitbusinessEuropean Neurology
researchProduct

Relationship between fragmented QRS and no-reflow, infarct size, and peri-infarct zone assessed using cardiac magnetic resonance in patients with myo…

2014

International audience; BACKGROUND: The relation between fragmented QRS complex (fQRS) and cardiac magnetic resonance parameters is poorly documented in ischemic cardiopathy. METHODS: Among 209 consecutive patients, those with fQRS were compared with those without fQRS. Cardiac magnetic resonance studies with late gadolinium-enhanced sequences were done during the week after acute myocardial infarction. RESULTS: fQRS was present in 113 (54%) patients, and associated with a significantly lower left ventricular ejection fraction, increased left ventricular volumes, a larger infarct size (IS), and a larger peri-infarct zone. Microvascular obstruction was more frequent in patients with fQRS (62…

Malemedicine.medical_specialtyMyocardial InfarctionMagnetic Resonance Imaging Cine[SDV.IB.MN]Life Sciences [q-bio]/Bioengineering/Nuclear medicineSeverity of Illness IndexVentricular Function Left[ SDV.IB.MN ] Life Sciences [q-bio]/Bioengineering/Nuclear medicineElectrocardiographyVentricular Dysfunction LeftInternal medicineMedicineHumansMyocardial infarctionProspective StudiesVentricular remodelingAgedUltrasonographyEjection fractionmedicine.diagnostic_testVentricular Remodelingbusiness.industryMagnetic resonance imagingStroke VolumeStroke volumeMiddle Agedmedicine.diseasePrognosiscardiovascular systemCardiologyDisease ProgressionMyocardial infarction complicationsFemaleMyocardial infarction diagnosisCardiology and Cardiovascular MedicinebusinessElectrocardiographyFollow-Up StudiesThe Canadian journal of cardiology
researchProduct

Enhanced external counterpulsation for treatment of refractory angina pectoris

2006

OBJECTIVE: Enhanced external counterpulsation (EECP) is a noninvasive, well-tolerated treatment, effective for managing patients with refractory angina pectoris. The aim of this study was to evaluate the efficacy of EECP to relieve symptoms, to decrease myocardial ischaemia and to improve cardiac performance in patients with intractable angina, refractory to surgical and medical treatment. METHODS: Twenty-five patients (24 men and one woman, mean age 65 years) with persistent ischaemia notwithstanding optimal medical therapy or after interventional or surgical procedure, received EECP sessions for 35 h. Each patient underwent dobutamine stress echocardiography before and after treatment. We…

Malemedicine.medical_specialtyMyocardial IschemiaIschemiaSeverity of Illness IndexVentricular Function LeftEnhanced external counterpulsationAngina PectorisAnginaRefractoryCounterpulsationInternal medicinemedicineHumansIn patientAgedAged 80 and overMedical treatmentbusiness.industrySignificant differenceStroke VolumeEnhanced external counterpulsation angina pectoris counterpulsationGeneral MedicineMiddle Agedmedicine.diseaseMyocardial ContractionTreatment OutcomeResearch DesignChronic DiseaseQuality of LifeCardiologyFemaleCardiology and Cardiovascular MedicineRefractory anginabusinessEchocardiography StressFollow-Up StudiesJournal of Cardiovascular Medicine
researchProduct

The neuropsychiatric profile of Parkinson's disease subjects with and without mild cognitive impairment

2012

Neuropsychiatric symptoms (NPS) are common clinical features of Parkinson's disease (PD). However, NPS profiles in PD subjects with mild cognitive impairment (MCI) have scarcely been investigated. We aimed to describe the NPS profiles of non-demented PD subjects with and without MCI. A total of 410 non-demented PD subjects were included. Of these, 164 were cognitively normal PD subjects (PD-cn), 142 PD had amnestic MCI (PD-aMCI), and 104 had PD with non-amnestic MCI (PD-naMCI). NPS were evaluated in accordance with the Neuropsychiatric Inventory (NPI). PD-aMCI subjects revealed the highest NPS burden, followed by PD-naMCI and then PD-cn. Overall, the most common NPS in PD-MCI were in order:…

Malemedicine.medical_specialtyNeurologyParkinson's diseaseNeuropsychological TestsIrritabilitySeverity of Illness Indexbehavioral disciplines and activitiesCognitionInternal medicinemental disordersSeverity of illnessmedicineHumansCognitive DysfunctionApathyParkinson’s disease Cognitive impairment Neuropsychiatric symptoms EpidemiologyBiological PsychiatryDepression (differential diagnoses)AgedSleep disordertechnology industry and agricultureParkinson DiseaseMiddle Agedmedicine.diseasePsychiatry and Mental healthNeurologyPhysical therapyAnxietyFemaleSettore MED/26 - NeurologiaAmnesiaNeurology (clinical)medicine.symptomPsychology
researchProduct

Predictive variables of spontaneous micturition recovery after acute urinary retention in men with benign prostatic enlargement: An observational pro…

2017

Objective: Acute urinary retention (AUR) is the sudden and painful inability to urinate spontaneously. AUR is one of the most significant complications of benign prostatic enlargement. The management of AUR is based on transurethral catheterization. Subsequent therapy is uncertain, but AUR seems to benefit from the use of alpha-blockers. The aim of this study was to evaluate the variables that could predict which patients would recover spontaneous micturition after trial without catheter. Methods: The present prospective observational study included men with AUR in an Italian tertiary care institute in 2016. Patients were catheterized and treated orally with fluoroquinolones, alpha-blockers…

Malemedicine.medical_specialtyNeurologymedia_common.quotation_subjectUrology030232 urology & nephrologyUrologyProstatic HyperplasiaUrinationUrinationSeverity of Illness IndexC-reactive protein03 medical and health sciences0302 clinical medicineProstatemedicineHumansProspective Studiesacute urinary retentionProspective cohort studymedia_commonAgedspontaneous micturition recoveryInternational Prostate Symptom ScorebiologyUrinary retentionbusiness.industryC-reactive proteinArea under the curveProstateOrgan SizeRecovery of FunctionMiddle AgedUrinary Retentionmedicine.anatomical_structureROC CurveNeurology030220 oncology & carcinogenesisArea Under CurveAcute Diseasebiology.proteinInternational Prostate Symptom Scoremedicine.symptombusinessUrinary Catheterization
researchProduct

Predicting conversion to dementia in mild cognitive impairment by volumetric and diffusivity measurements of the hippocampus.

2005

In our prospective study of diffusion tensor imaging (DTI), we measured hippocampal mean diffusivity (MD) and volumes in amnestic mild cognitive impairment (MCI). Thirteen MCI patients were followed-up by clinical assessment over a mean 112-year period. MCI patients who converted to dementia (6 of 13) during the observation period had slightly elevated left hippocampal mean diffusivity at baseline compared with MCI patients who remained clinically stable. Hippocampal volumes as well as baseline verbal memory and MMSE did not differ significantly between stable MCI patients and converters. Hippocampal diffusivity was superior to hippocampal volumes for prediction of conversion to dementia in…

Malemedicine.medical_specialtyNeuroscience (miscellaneous)Hippocampal formationNeuropsychological Testsbehavioral disciplines and activitiesHippocampusSeverity of Illness IndexCentral nervous system diseasePredictive Value of TestsInternal medicinemental disordersmedicineHippocampus (mythology)DementiaHumansRadiology Nuclear Medicine and imagingProspective StudiesProspective cohort studyAgedCognitive disordermedicine.diseasenervous system diseasesPsychiatry and Mental healthDiffusion Magnetic Resonance ImagingCardiologyDementiaFemaleVerbal memoryPsychologyCognition Disordershuman activitiesNeuroscienceDiffusion MRIPsychiatry research
researchProduct

Recurrence of Acute Gallstone Pancreatitis and Relationship with Cholecystectomy or Endoscopic Sphincterotomy

2004

To determine the prevalence of recurrence of gallstone pancreatitis, its clinical features, and the presence of prognostic factors of recurrence.From January 1, 2000 to August 31, 2003, 233 patients admitted with acute gallstone pancreatitis (AGP) were prospectively studied. Patients were divided into two groups: recurrent and nonrecurrent group. Clinical, analytical, radiological, prognostic parameters, and severity (Atlanta criteria) were assessed, along with the performance of cholecystectomy or endoscopic sphincterotomy (ES). Clinical features of recurrence were analyzed. Univariate (chi(2), Student's t-test) and multivariate tests were performed. Statistical significance was assumed if…

Malemedicine.medical_specialtyPancreatic diseasemedicine.medical_treatmentGallstonesSeverity of Illness IndexSphincterotomy EndoscopicRecurrenceRisk FactorsSeverity of illnessPrevalenceHumansMedicineCholecystectomyProspective StudiesProspective cohort studyAgedChi-Square DistributionHepatologymedicine.diagnostic_testbusiness.industryGallbladderGeneral surgeryGastroenterologyMiddle AgedPrognosismedicine.diseaseSurgeryEndoscopyLogistic Modelsmedicine.anatomical_structurePancreatitisAcute DiseasePancreatitisFemaleCholecystectomybusinessChi-squared distributionThe American Journal of Gastroenterology
researchProduct

Effects of supervised slackline training on postural instability, freezing of gait, and falls efficacy in people with Parkinson's disease.

2016

The aim of this study was to assess whether supervised slackline training reduces the risk of falls in people with Parkinson's disease (PD).Twenty-two patients with idiopathic PD were randomized into experimental (EG, N = 11) and control (CG, N = 11) groups. Center of Pressure (CoP), Freezing of Gait (FOG), and Falls Efficacy Scale (FES) were assessed at pre-test, post-test and re-test. Rate perceived exertion (RPE, Borg's 6-20 scale) and local muscle perceived exertion (LRPE) were also assessed at the end of the training sessions.The EG group showed significant improvements in FOG and FES scores from pre-test to post-test. Both decreased at re-test, though they did not return to pre-test l…

Malemedicine.medical_specialtyParkinson's diseasemedicine.medical_treatmentFalls efficacyPostural instabilityPoison controlSeverity of Illness Index03 medical and health sciences0302 clinical medicineLumbarPhysical medicine and rehabilitationInjury preventionmedicineHumansExerciseGaitPostural BalanceFatigueAgedAged 80 and overRehabilitationbusiness.industryRehabilitationMotor controlParkinson Disease030229 sport sciencesFearMiddle Agedmedicine.diseaseExercise TherapyLower ExtremitySpainPhysical therapyAccidental FallsFemalebusiness030217 neurology & neurosurgeryDisability and rehabilitation
researchProduct