Search results for "solu"
showing 10 items of 7577 documents
Control of Morphology and Corona Composition in Aggregates of Mixtures of PS-b-PAA and PS-b-P4VP Diblock Copolymers: Effects of Solvent, Water Conten…
2014
The morphologies and corona compositions in aggregates of mixtures of PS-b-PAA and PS-b-P4VP diblock copolymers are influenced by controllable assembly parameters such as water content, block copolymer molar ratios, and solvent effects as well as the hydrophilic block lengths and block length ratios. All these factors can affect the morphology of the aggregates as well as their corona composition, the latter especially in vesicles, where two interfaces are involved. The morphologies and corona compositions of the aggregates were investigated by transmission electron microscopy and electrophoretic mobility, respectively. They depend, to a large extent, on the solubility of P4VP and PAA in th…
Control of Corona Composition and Morphology in Aggregates of Mixtures of PS-b-PAA and PS-b-P4VP Diblock Copolymers: Effects of pH and Block Length
2014
The corona compositions and morphologies in aggregates of mixtures of amphiphilic polystyrene-block-poly(acrylic acid) (PS-b-PAA) and polystyrene-block-poly(4-vinylpyridine) (PS-b-P4VP) diblock copolymers are influenced by controllable assembly parameters such as the hydrophilic block length and solution pH. The morphologies and corona compositions of the aggregates were investigated by transmission electron microscopy and electrophoretic mobility, respectively. When mineral acids or bases are present during aggregate formation, they can exert a strong influence on the corona composition. Morphology changes were also seen with changing pH, as well as changes in corona composition, specifica…
Plasticizer extraction of Taxol infusion solution from various infusion devices.
1996
Taxol solution extracts the plasticizer DEHP (di(2-ethylhexyl)phthalate) from polyvinyl chloride (PVC) materials. In order to minimize patient exposure to DEHP, Taxol solutions should be prepared and administered in PVC-free materials. Particulate matter may form in Taxol infusion solution over time, so that in-line filtration with microporous membranes not greater than 0.22 microns is advisable. The purpose of this study was to evaluate the suitability of various administration- and in-line filter-sets for Taxol application. The extent of leached DEHP was determined using a Reversed Phase HPLC assay specific for DEHP. The four tested administration-sets, labeled as PVC-free, were all found…
M11_Microfluidics_for_CNT
2018
The subtle solubility of water in n-decane causes leaking of the droplet content. If the n-decane flows by static droplets, it carries the water slowly away up to the total disappearance of the droplets.
Prolactin supplementation to culture medium improves beta-cell survival
2010
OBJECTIVES.: Recent studies demonstrated that prolactin (PRL) has beneficial effects on β cells for islet transplantation. We examined the effect of human recombinant PRL (rhPRL) supplementation to the culture media to determine its potential use in the context of clinical islet transplantation. MATERIALS AND METHODS.: Each human islet isolated from 14 deceased multiorgan donors was cultured in Miami modified media-1 supplemented with or without rhPRL (500 μg/L) for 48 hr. β-Cell survival and proliferation (BrdU and Ki-67) were determined by laser scanning cytometry. The cytoprotective effects of rhPRL against noxious stimuli were assessed by flow cytometry (tetramethylrhodamine ethyl ester…
Ocular gelling microspheres: in vitro precorneal retention time and drug permeation through reconstituted corneal epithelium.
2008
Purpose: The model drug norfloxacin (NOR)was encapsulated into trehalose (TRH) and hydroxyethylcellulose(NAT) microspheres to obtain a novel gelling ophthalmic delivery system for prolonged release on corneal tissue. Methods: We assessed NOR release from microspheres, prepared by the emulsion-solvent evaporation method. A new in vitro tear turnover model, including inserts containing reconstituted human corneal epithelium (RHC), was designed to evaluate the TRH/NAT microspheres’ precorneal retention time. Bioadhesive properties of TRH/NAT microspheres were validated by using drug-loaded microspheres prepared with gelatine (GLT) commonly used as reference material in adhesion studies. Result…
The Large Hadron–Electron Collider at the HL-LHC
2021
The Large Hadron-Electron Collider (LHeC) is designed to move the field of deep inelastic scattering (DIS) to the energy and intensity frontier of particle physics. Exploiting energy-recovery technology, it collides a novel, intense electron beam with a proton or ion beam from the High-Luminosity Large Hadron Collider (HL-LHC). The accelerator and interaction region are designed for concurrent electron-proton and proton-proton operations. This report represents an update to the LHeC's conceptual design report (CDR), published in 2012. It comprises new results on the parton structure of the proton and heavier nuclei, QCD dynamics, and electroweak and top-quark physics. It is shown how the LH…
Partition of volatile compounds in pea globulin–maltodextrin aqueous two-phase system
2014
International audience; This study is based on the assumption that the off-flavour of pea proteins might be decreased using the retention of volatile compounds by a mixture with another biopolymer. The partition of volatile compounds in an aqueous system containing pea protein and maltodextrins was followed under thermodynamic incompatibility conditions. Firstly, the phase diagram of the system was established. Then, the partition of aroma compounds between the phase rich in protein and the phase rich in maltodextrin was measured by SPME–GC–MS. There was a transfer of volatile compounds during phase separation. Variations of pH were also used to vary the retention of volatile compounds by p…
Didáctica de las ciencias experimentales y sociales
2006
Resumen tomado de la publicación Propone un conjunto de ideas que pretenden contribuir a una mayor formalización de la didáctica de las ciencias, con especial atención a la enseñanza por investigación. La enseñanza por investigación es el método recomendado por la mayoría de especialistas en didáctica de las ciencias desde los albores de la disciplina. Sin embargo no existe un discurso coherente entre los distintos investigadores. Valencia Universidad de León. Facultad de Educación. Servicio de Biblioteca; Campus de Vegazana, s. n.; 24071 León; Tel. +34987291146; Fax +34987291145; bufed@unileon.es; bufed1@unileon.es ESP
Percepción del alumnado de Educación Secundaria sobre la mediación escolar en Castellón y Valencia
2016
La realidad social, en constante proceso de cambio, exige al sistema educativo un esfuerzo por actualizar las respuestas educativas frente a la mejora de la convivencia. Es en este contexto en el que la mediación ha dejado ver sus potencialidades educativas, ya que influye sobre la mejora del individuo, de las relaciones interpersonales y del clima escolar. No obstante, son escasas las investigaciones orientadas a conocer el impacto de la misma. En este artículo presentamos un estudio dirigido a conocer la valoración de la mediación atendiendo a las opiniones del alumnado de cinco centros educativos de secundaria de Valencia y cuatro de Castellón. Asimismo, se pretende detectar si existen d…