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Emergence in 2017-2019 of novel reassortant equine-like G3 rotavirus strains in Palermo, Sicily.

2021

Rotavirus A (RVA) is a major etiologic agent of gastroenteritis in children worldwide. Hospital-based surveillance of viral gastroenteritis in paediatric population in Palermo (Italy) from 2017 onwards revealed a sharp increase in G3P[8] RVAs, accounting for 71% of all the RVAs detected in 2019. This pattern had not been observed before in Italy, with G3 RVA usually being detected at rates lower than 3%. In order to investigate this unique epidemiological pattern, the genetic diversity of G3 RVAs identified during a 16-year long surveillance (2004-2019) was explored by systematic sequencing of the VP7 and VP4 genes and by whole genome sequencing of selected G3 strains, representative of the…

Evolution of DS-1-like human G2P[4] rotaviruses assessed by complete genome analyses

2013

Group A rotaviruses (RVAs) are a leading cause of viral gastroenteritis in children, with G2P[4] RVA being one of the most common human strain worldwide. The complete genome sequences of nine G2P[4] RVA strains, selected from a 26-year archival collection (1985-2011) established in Palermo/Italy, were determined. A strain associated with a peak of G2P[4] RVA activity in 1996 resembled a reassortant strain identified in Kenya in 1982 and completely differed in the genomic make up from more recent strains that circulated during 2004-2011. Conversely, the 2004-2011 G2P[4] RVAs were genetically more similar to contemporary RVA strains circulating globally. Recent G2P[4] strains possessed either…

A feline rotavirus G3P[9] carries traces of multiple reassortment events and resembles rare human G3P[9] rotaviruses.

2011

The full-length genome sequence of a feline G3P[9] rotavirus (RV) strain, BA222, identified from the intestinal content of an adult cat, was determined. Strain BA222 possessed a G3-P[9]-I2-R2-C2-M2-A3-N1-T3-E2-H3 genomic constellation, differing substantially from other feline RVs. Phylogenetic analyses of each genome segment revealed common origins with selected animal and zoonotic human RVs, notably with rare multi-reassortant human G3P[9] RVs (Ita/PAI58/96 and Ita/PAH136/96). Altogether, the findings suggest that feline RVs are genetically diverse and that human RVs may occasionally originate either directly or indirectly (via reassortment) from feline RVs.

Bezier curves approximation of triangularized surfaces using SVG

2006

This paper presents a technique to convert surfaces, obtained through a Data Dependent Triangulation, in Bezier Curves by using a Scalable Vector Graphics File format. The method starts from a Data Dependent Triangulation, traces a map of the boundaries present into the triangulation, using the characteristics of the triangles, then the estimated barycenters are connected, and a final conversion of the resulting polylines in curves is performed. After the curves have been estimated and closed the final representation is obtained by sorting the surfaces in a decreasing order. The proposed techniques have been compared with other raster to vector conversions in terms of perceptual quality.

Ubiquitin ligase Rsp5p is involved in the gene expression changes during nutrient limitation inSaccharomyces cerevisiae

2009

Rsp5p is an essential ubiquitin ligase involved in many different cellular events, including amino acid transporters degradation, transcription initiation and mRNA export. It plays important role in both stress resistance and adaptation to the change of nutrients. We have found that ubiquitination machinery is necessary for the correct induction of the stress response SPI1 gene at the entry of the stationary phase. SPI1 is a gene whose expression is regulated by the nutritional status of the cell and whose deletion causes hypersensitivity to various stresses, such as heat shock, alkaline stress and oxidative stress. Its regulation is mastered by Rsp5p, as mutations in this gene lead to a lo…

Transformando las prácticas de evaluación en las agencias de innovación para fomentar transiciones hacia la sostenibilidad

2019

The aim of the study is to identify different styles and practices for evaluation of innovation policies based on different orientations, focusing on the case of the paradigm of transformative change to foster transitions towards sustainability, and the problems associated with its application. The study is exploratory, and it uses public funding agencies for innovation as strategic research settings. Based on the information provided by the experience of an international consortium participated by funding agencies from different countries, the main concepts and problems presented in the theoretical debate are illustrated. Finally, the main contributions of the study to the theory and pract…

ENHANCEMENT OF WHEAT VIRUS-RESISTANCE AT APPLICATION OF THE SE NANOPARTICLES CITRATES AND CONSORTIUM OF SOIL MICROORGANISMS

2021

The influence of pre-sowing seed treatments of selenium nanocitrates (SeNPs) and application of soil formed microorganism consortium (biological preparation (BP) Extrakon) on wheat plants infected with wheat streak mosaic virus (WSMV) were investigated in greenhouse and fields conditions in 2018-2019 (on territories of Zabolotny Institute of Microbiology and Virology of NASU). The pre-sowing seed treatments of 1% selenium nanocitrates (SeNPs) with application of BP Extrakon initiating the growth of juvenile wheat in laboratory experiments were found. In the field experiment on variants of WSMV-infected plants, two weeks after inoculation (tillering stage), we observed the appearance of char…

ChemInform Abstract: Dimerization and Self-Sorting of Tetraurea Calix[4]arenes

2009

Mechanics and self-organization in tissue development

2021

Self-organization is an all-important feature of living systems that provides the means to achieve specialization and functionality at distinct spatio-temporal scales. Herein, we review this concept by addressing the packing organization of cells, the sorting/compartmentalization phenomenon of cell populations, and the propagation of organizing cues at the tissue level through traveling waves. We elaborate on how different theoretical models and tools from Topology, Physics, and Dynamical Systems have improved the understanding of self-organization by shedding light on the role played by mechanics as a driver of morphogenesis. Altogether, by providing a historical perspective, we show how i…

Sermon que en la solemne accion de gracias celebrada por el feliz alumbramiento de la princesa nuestra señora, y beneficio de la paz, el dia 21 de di…

Fris, filets Text a 1 col. - Notes a peu de p. - Reclams Sign.: A-E4